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Ivey introduced as new Notre Dame coach, succeeding McGraw

Niele Ivey is coming home.




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Q&A with Adam Ferguson

Each year the Library hosts the popular World Press Photo exhibition, bringing together award-winning photographs from t




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Fundamentals of cone regression

Mariella Dimiccoli.

Source: Statistics Surveys, Volume 10, 53--99.

Abstract:
Cone regression is a particular case of quadratic programming that minimizes a weighted sum of squared residuals under a set of linear inequality constraints. Several important statistical problems such as isotonic, concave regression or ANOVA under partial orderings, just to name a few, can be considered as particular instances of the cone regression problem. Given its relevance in Statistics, this paper aims to address the fundamentals of cone regression from a theoretical and practical point of view. Several formulations of the cone regression problem are considered and, focusing on the particular case of concave regression as an example, several algorithms are analyzed and compared both qualitatively and quantitatively through numerical simulations. Several improvements to enhance numerical stability and bound the computational cost are proposed. For each analyzed algorithm, the pseudo-code and its corresponding code in Matlab are provided. The results from this study demonstrate that the choice of the optimization approach strongly impacts the numerical performances. It is also shown that methods are not currently available to solve efficiently cone regression problems with large dimension (more than many thousands of points). We suggest further research to fill this gap by exploiting and adapting classical multi-scale strategy to compute an approximate solution.




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Chaffetz: I don't understand why Adam Schiff continues to have a security clearance

Fox News contributor Jason Chaffetz and Andy McCarthy react to House Intelligence transcripts on Russia probe.





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god damn you john bolton for trying to kill me





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Notre-Dame Restoration Pauses Amid France's Two-Week Lockdown

Lead decontamination policies enacted in August are now in conflict with measures to prevent spread of COVID-19




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5.4-Magnitude Earthquake Damages Zagreb Cathedral, Museums

The tremors, which arrived in the midst of the COVID-19 pandemic, was the worst the Croatian capital has seen in 140 years




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Two Men Arrested After Trying to Steal Stones From Notre-Dame

The suspects were found drunk and hiding under a tarpaulin, reportedly in possession of small stones from the fire-ravaged cathedral




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5.4-Magnitude Earthquake Damages Puerto Rican Museums

The Museo de la Massacre de Ponce and Casa Paoli were among the buildings affected by Saturday's tremors




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A Tour of Beauty Industry Pioneer Madam C.J. Walker’s Indianapolis

The hair-care magnate at the center of the new Netflix series 'Self Made' left her imprint on the city where she launched her career




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Fifty Years Ago, the Crew of the Damaged Apollo 13 Came Home

Using the lunar module as a lifeboat and employing techniques never before considered, the astronauts' ordeal ended triumphantly




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What Kind of Damage Can a Medieval War Hammer Do?

A contemporary weapons expert is about to test a medieval war hammer on a steel breastplate from that era. The aim is to find out how much damage this fearsome instrument of death could deal.




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Industrial building in Thunder Bay damaged in Thursday afternoon fire

An industrial building in Thunder Bay was slightly damaged in a fire late Thursday afternoon.



  • News/Canada/Thunder Bay

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Fort Vermilion residents deal with extensive flood damage

Residents are cleaning up damage to hundreds of homes and businesses caused by floods in the northern Alberta hamlet of Fort Vermilion.



  • News/Canada/Edmonton

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Province to spend $147 million on northern Alberta communities damaged by floods

Disaster relief funding for punishing spring floods is welcome news to civic leaders in northern Alberta.



  • News/Canada/Edmonton

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Fehmi Mehmeti: The Central Bank of the Republic of Kosovo has taken steps to protect the economy from Covid-19 damages

Speech by Mr Fehmi Mehmeti, Governor of the Central Bank of the Republic of Kosovo, at the press conference where the details of the measures taken by the CBK for maintaining health in the economy were given, Pristina, 3 April 2020.




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Notre Dame women's basketball coach Muffet McGraw retires after 33 years, 2 titles

Notre Dame women's basketball coach Muffet McGraw is retiring after winning two national championships in 33 years with the Irish.




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Film view with Damien Smith

RADIOACTIVE (12A)




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Letters: SPFL has thrown money at immediate issue without making any fundamental changes

LIKE many of your readers, I would imagine, I am a fairly enthusiastic armchair football supporter with no real club affiliation.




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Amsterdam final secures grassroots legacy

Youth and grassroots football was the focus as UEFA President Michel Platini attended the finals of a grassroots programme and a new maxi-pitch was opened in Amsterdam.




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Report Suggests Ways to Offset Economic Damage of Climate Change

Source: Public News Service - Economists warn that the costs of climate change in the U.S. – including from the health impacts of air pollution and natural disasters such as hurricanes and wildfires – could top $350 billion annually in the next 10 years.




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Parental Smoking and Vascular Damage in Their 5-year-old Children

Smoking during pregnancy has been related to thicker carotid intima media thickness in young adults, and this was also shown in neonates.

This study is the first to show that the effect of smoking during pregnancy on the vasculature of children is (still) visible at the age of 5 years. Pregnancy appears to be the critical period for this damage to occur. (Read the full article)




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Prevalence and Correlates of Low Fundamental Movement Skill Competency in Children

Children’s mastery of fundamental movement skills is correlated with a number of health benefits, including higher levels of physical activity, cardiorespiratory fitness, perceived scholastic and athletic competence, and lower levels of overweight.

This is the first study to examine the associations between low skill competence (a new and novel way to report motor skills) and a range of health-related and sociodemographic factors in a large representative sample of children and youth. (Read the full article)




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Moisture Damage and Asthma: A Birth Cohort Study

Moisture damage and mold increase the risk of asthma and asthmatic symptoms. However, the location of the damage, or the specific group of children who are at greater risk of asthma, is rarely taken into account.

Inspector-observed moisture damage or mold in the child’s bedroom, living room, or kitchen increased the risk of asthma and persistent asthma during a 6-year follow-up. Atopic children may be more susceptible to the effects of moisture damage and mold. (Read the full article)




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John Solomon on Adam Schiff: he’s “a modern day Joe McCarthy”

Source: www.letfreedomringblog.com - Saturday, May 09, 2020
John Solomon has worked overtime and then some to rip Adam Schiff’s mask off. So have Catherine Herridge, Sara Carter, Lee Smith, Gregg Jarrett, Kim Strassel, Mollie Hemmingway and Byron York. Solomon’s article highlights how utterly dishonest Adam Schiff is. Ditto with the upper echelon of the FBI. Strap yourself in. This isn’t a short ride. The pursuit of the truth ended Thursday when the Justice Department formally asked a court to vacate Flynn’s conviction and end the criminal case, acknowledging the former general had indeed been cleared by FBI agents and that the bureau did not have a lawful purpose when it interviewed him in January 2017. Attorney General William Barr put it more bluntly in an interview Thursday : “They kept it open for the express purpose of trying to catch, to lay a perjury trap for General Flynn.” According to Solomon’s reporting, the FBI didn’t have a reason to investigate Gen. Flynn: 3. Case closed memo. FBI agents wrote a memo to close the investigation of Flynn on Jan. 4, 2017, writing they found “no derogatory” evidence that Flynn committed a crime or posed a national security threat. FBI management then ordered the closure to be rescinded and pivoted toward trying lure Flynn into an interview. https://justthenews.com/accountability/russia-and-ukraine-scandals/fbi-found-no-derogatory-russia-evidence-flynn-planned Corrupt FBI agent Peter Strzok allegedly ordered Crossfire Razor, the codename for th

All Related




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Novel peptide from commensal Staphylococcus simulans blocks MRSA quorum sensing and protects host skin from damage [Mechanisms of Action]

Recent studies highlight the abundance of commensal coagulase-negative staphylococci (CoNS) on healthy skin. Evidence suggests that CoNS actively shape the skin immunological and microbial milieu to resist colonization or infection by opportunistic pathogens, including methicillin resistant Staphylococcus aureus (MRSA), in a variety of mechanisms collectively termed colonization resistance. One potential colonization resistance mechanism is the application of quorum sensing, also called the Accessory Gene Regulator (agr) system, which is ubiquitous among staphylococci. Common and rare CoNS make autoinducing peptides (AIPs) that function as MRSA agr inhibitors, protecting the host from invasive infection. In a screen of CoNS spent media we found that Staphylococcus simulans, a rare human skin colonizer and frequent livestock colonizer, released potent inhibitors of all classes of MRSA agr signaling. We identified three S. simulans agr classes, and have shown intraspecies cross-talk between non-cognate S. simulans agr types for the first time. The S. simulans AIP-I structure was confirmed, and the novel AIP-II and AIP-III structures were solved via mass spectrometry. Synthetic S. simulans AIPs inhibited MRSA agr signaling with nanomolar potency. S. simulans in competition with MRSA reduced dermonecrotic and epicutaneous skin injury in murine models. Addition of synthetic AIP-I also effectively reduced MRSA dermonecrosis and epicutaneous skin injury in murine models. These results demonstrate potent anti-MRSA quorum sensing inhibition by a rare human skin commensal, and suggest that cross-talk between CoNS and MRSA may be important in maintaining healthy skin homeostasis and preventing MRSA skin damage during colonization or acute infection.




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P Chidambaram Welcomes Centre's Decision To Borrow Rs 4.2 Lakh Crore

Senior Congress leader P Chidambaram today welcomed the Centre's decision to borrow additional 4.2 lakh crore and said it should be used to provide relief to the poor and re-start the economy.




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Delaware requests emergency declaration from USDA for crop damage due to recent storms

DOVER, Del. — Too much rain at the wrong time, like Delaware experienced in April and May, has destroyed several high dollar crops and threatens the yield of many others, leaving farmers to wonder what the future holds. In surveying the state and listening to farmers, Secretary of Agriculture Michael T. Scuse made a request […]




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Severe crop damage at Redden State Forest creates public deer harvest opportunities to assist local farmers

DOVER, Del. — A recent increase in severe deer damage to agricultural crops on two portions of Redden State Forest in Sussex County has created public deer harvest opportunities to assist local farmers. Through a partnership with DNREC’s Division of Fish & Wildlife, the Delaware Department of Agriculture’s Forest Service is opening specific portions of […]




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TRAFFIC ALERT - Closure of Records Pond Dam for Improvements

Laurel --

Time and Dates: 7:00 a.m. on March 2, 2020 until spring 2021

Location: Willow Street (Records Pond Dam) between Delaware Avenue and Front Street, Laurel

The Delaware Department of Transportation in conjunction with the Delaware Department of Natural Resources and Environmental Control announces that Records Pond Dam will be closed for improvements to the dam. The closure will include Willow Street across Records Pond Dam and all facilities located adjacent to the dam. These facilities include but are not limited to the boat ramp, pier, parking areas, and pedestrian fishing points. [More]




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TRAFFIC ALERT - Railroad Maintenance Will Require the Closure of Adams Road

Greenwood --

DelDOT announces to motorists that Delmarva Central Railroad will be resurfacing and performing general maintenance on their railroad crossing at Adams Road between Newton Road and US 13.

The closure will begin at 5:00 a.m. on Sunday, April 19, 2020 until 11:45 p.m. on Tuesday, April 21, 2020, pending weather.

Detour Routes:

Northbound: Adams Road on Newton Road to US 13 and return to Adams Road. [More]




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Records Pond dam and fishing piers closing March 2

The dam and associated fishing access areas at Records Pond in Laurel will be closed to public use during reconstruction of the dam beginning March 2.




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St. Jones Reserve trail in Dover temporarily closed due to storm damage

The trail at the St. Jones Reserve (DNERR) near Dover is temporarily closed past the first marsh boardwalk as a result of damage caused by storms.




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Paris: Builders back at Notre-Dame cathedral after coronavirus shutdown

French President Emmanuel Macron promised to rebuild within five years but work so far has been slow. Delays were caused by toxic lead released by the fire, winter storms and then by the COVID-19 epidemic which closed the site in March.




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RECORDS POND DAM IMPROVEMENTS

RECORDS POND DAM IMPROVEMENTS




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The best college sports comebacks we ever saw: Notre Dame's meltdown, George Mason's shocker

ESPN's team of college writers and reporters reflects on the stunning reversals of fortune they have covered during their careers.




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BoardSurfers: Training Insights - Fundamentals of PDN for Design and PCB Layout

What is a Power Distribution Network (PDN) after all but resistance, inductance, and capacitance in the PCB and components? And, of course, it is there to deliver the right current and voltage to each component on your PCB. But is that all? Are there oth...(read more)




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News18 Urdu: Latest News Andaman

visit News18 Urdu for latest news, breaking news, news headlines and updates from Andaman on politics, sports, entertainment, cricket, crime and more.




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News18 Urdu: Latest News Dama

visit News18 Urdu for latest news, breaking news, news headlines and updates from Dama on politics, sports, entertainment, cricket, crime and more.




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News18 Urdu: Latest News Damoh

visit News18 Urdu for latest news, breaking news, news headlines and updates from Damoh on politics, sports, entertainment, cricket, crime and more.





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The Lewis River Merwin Dam: harvest, habitat, hatcheries and hydro

On Tuesday, July 23, about 30 HydroVision attendees had to privilege of touring the 136-MW Lewis River hydropower plant located at the Merwin Dam in Ariel, Washington. The dam was constructed in 1931 and has four penstocks, which today feed three turbines. The turbines were installed in 1931, 1949 and 1958, respectively. The fourth penstock, which was the focus of much of the tour, is for fish passage.




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University of Notre Dame breaks ground on 2.5-MW hydroelectric generation facility

The University of Notre Dame and South Bend’s Venues Parks & Arts have broken ground on a 2.5-MW hydroelectric generation facility at an existing city-owned dam on the St. Joseph River in downtown South Bend, Ind.




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Thailand planning massive floating solar power plants on hydropower dam reservoirs

Thailand plans to build the world’s largest floating solar farms to power Southeast Asia’s second-largest economy and to boost the country’s share of clean energy.




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Thailand planning massive floating solar power plants on hydropower dam reservoirs

Thailand plans to build the world’s largest floating solar farms to power Southeast Asia’s second-largest economy and to boost the country’s share of clean energy.




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Dam safety, dam monitoring, dam repair news and more

Collection of articles covering safety and security of dams and civil structures




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Two Workers Die in “Landslide” at Hamzadere Dam Irrigation System in Turkey

Two construction workers died as the result of a landslide and additional workers were injured on May 22 at the construction site of the Hamzadere Dam Irrigation System in the Ipsala district of Edirne, Turkey. Edirne is in the northwestern-most part of the Turkey near its border with Greece.




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Strong fall chinook returns reported at Bonneville Dam

According to the Fish Passage Center website, adult fall chinook counted at Bonneville Dam were 212,618 as of Sept. 3, the second highest on record since counting began in 1938.




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Potsdam hydroelectric project has rehabilitation and new construction goals

According to the Federal Register, potential power is presently unutilized at the 800-kW East powerhouse and proposed 700-kW West powerhouse for the Potsdam hydroelectric project on the Raquette River in Lancaster County, New York. The proposed West powerhouse received a Federal Energy Regulatory Commission exemption from licensing in 1981.