A vertical centrifugal separator includes a casing, a bowl that is rotatably housed in the casing and provided to separate a solution to be processed which is supplied to an interior of the bowl into a liquid and a solid by an action of centrifugal force and discharge the liquid and the solid, and a discharge assembly that is rotatably housed in the bowl and provided to discharge the solid in the bowl. The bowl and the discharge assembly each have an engagement portion that is engaged or disengaged when the bowl and the discharge assembly are moved relative to each other in an axial direction and a position adjustment mechanism for adjusting a phase between the discharge assembly and the bowl relative to a rotation axis, for example, at a single relative position.

Embodiments of the present invention generally relate to methods and apparatus for centrifugal separation. In one embodiment, a separator includes an outer tubular having ends sealed from the environment and an inner tubular. The inner tubular is disposed within the outer tubular, has ends in fluid communication with a bore of the outer tubular, and is attached to the outer tubular. The separator further includes an inlet. The inlet is disposed through a wall of the outer tubular, in fluid communication with a bore of the inner tubular, and tangentially attached to the inner tubular so that fluid flow from the inlet to the inner tubular is centrifugally accelerated. The separator further includes a gas outlet in fluid communication with the outer tubular bore; and a liquid outlet in fluid communication with the outer tubular bore.

In a decanter centrifuge a bowl is provided and rotates in use around a horizontal axis of rotation, a base plate provided at one longitudinal end of said bowl, the base plate having an internal side and an external side, an outlet opening provided in said base plate, the outlet opening extending through a first angular interval relative to the axis of rotation, and a wall projecting from the external side of said base plate, wherein the wall extends from the vicinity of the outlet opening towards a rim of the base plate, the wall extending through a second angular interval, the second angular interval being at least 30°, and the wall having in a radial plane perpendicular to the axis of rotation an inclination relative to the radial direction of at least 60°.

A separation cone (30) is mounted into the interior chamber of a centrifugal separator rotor (10), which comprises a cover (14) releasably connected to a base (16), in order to provide a frusto-conical wall subdividing the chamber into upper and lower regions. This slows the passage of fluid from the upper to the lower region, which takes place via openings (24) and/or via a gap between the inner rim (32) of the cone (30) and the axial inlet tube (12). The separation cone (30) is connected to the cover (14) by a releasable snap fit arrangement, such as by deflectable tabs (38) around the periphery of the separation cone (30) engaging into a groove (15) around the interior surface adjacent a lower edge of the cover (14). This allows there to be a predetermined sequence of servicing operations and ensures that the separation cone (30) will reliably stay with the cover (14) when the cover is removed.

Disclosed are a polysiloxane-modified polyhydroxy polyurethane resin characterized by being derived from a reaction between a 5-membered cyclic carbonate polysiloxane compound represented by the below-described formula (1) and an amine compound, and its production process; and a resin composition, thermal recording medium, imitation leather, thermoplastic polyolefin resin skin material, weather strip material, and weather strip, all of which make use of the resin. wherein A means

A biomass gasification gas purification system includes a dust collector for removing dust in biomass gasification gas (containing tar components) acquired by gasifying biomass by a biomass gasification furnace, a desulfurizer for removing sulfur oxide components in the dust-removed biomass gasification gas, a pre-reforming reactor for reforming tar components in the desulfurized biomass gasification gas, a steam feed unit for feeding steam to an upstream side of the pre-reforming reactor, and a natural-gas feed unit for feeding natural gas on an upstream side of the desulfurizer.

A gasification-liquefaction disposal method, system and equipment for MSW are disclosed. The method involves the MSW pretreatment of dehydrating and separating, thus reducing water and inorganic substance content of the waste. Then, the MSW is introduced into a plasma gasifier (23) by a carbon dioxide air-sealed feeding device (13) and gasified therein to obtain hydrogen-rich syngas. The hydrogen-rich syngas is then cooled, deacidified, dedusted and separated to obtain carbon dioxide. Then, the hydrogen-rich syngas is catalyzed to produce methanol product in a methanol synthesis reactor (52). The separated carbon dioxide is sent back to a carbonation reaction chamber (2007) of a gasification system to perform carbonation reaction with calcium oxide, thereby releasing heat to provide assistant heat energy for gasification and avoiding greenhouse gas from being discharged into environment. Exhaust gas is returned to the plasma gasifier (23) for remelting treatment, thus forming a closed-loop circulation production system and realizing the disposal of the MSW with zero discharge and no pollution, thereby avoiding dioxin pollution and converting the MSW to chemical raw materials and fuel needed by mankind. The method, system and equipment are suitable for harmless and recycling disposal of MSW, industrial high polymer waste, composting waste and waste in waste sorting sites.

The present invention aims to simulate a response more similar to a actual machine while inhibiting load increase in analog operation. Program configuration of the present invention is a component of a simulation program for circuit design, which is executed by a computer. The computer includes an operation portion, a storage portion, a manipulation portion, and a display portion, so that the computer exerts a function of a circuit design simulator, and as a macro model of an operational amplifier for use in the circuit design simulator, enabling the computer to act by simulating a response of the operational amplifier on the circuit design simulator. The macro model of the operational amplifier includes a control portion (LMT1) for generating output exception in the event of input exception or power supply exception of the operational amplifier.

Embodiments include methods of identifying a personalized cardiovascular device based on patient-specific geometrical information, the method comprising acquiring an anatomical model of at least part of the patient's vascular system; performing, using a processor, one or more of geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis on the anatomical model; and identifying, using the processor, a personalized cardiovascular device for the patient, based on results of one or more of the geometrical analysis, computational fluid dynamics analysis, and structural mechanics analysis of anatomical model.

Embodiments include methods of identifying a personalized cardiovascular device based on patient-specific geometrical information, the method comprising: generating a patient specific model of at least a portion of a patient's vasculature from image data of the patient's vasculature and one or more measured or estimated physiological or phenotypic parameters of the patient; determining pathology characteristics from cardiovascular geometry of the patient specific model; defining an objective function for a device based on design considerations and one or more estimates of hemodynamic and mechanical characteristics; optimizing the objective function, by simulating at least one change in devices and evaluating the objective function using fluid dynamic or structural mechanic analysis; and using the optimized objective function to either (i) select a device from a set of available devices or (ii) manufacture a desired device.

A method is described for improving the uniformity over a predetermined substrate area of a spectral response of photonic devices fabricated in a thin device layer. The method includes (i) establishing an initial device layer thickness map for the predetermined area, (ii) establishing a linewidth map for the predetermined area, and (iii) establishing an etch depth map for the predetermined area. The method further includes, based on the initial device layer thickness map, the linewidth map and the etch depth map, calculating an optimal device layer thickness map and a corresponding thickness correction map for the predetermined substrate area taking into account photonic device design data. Still further, the method includes performing a location specific corrective etch process in accordance with the thickness correction map.

An implantable medical device lead having a flow measurement sensor mounted thereon is provided with a capsule mounted proximate to the sensor. The capsule is used to house electrical circuitry corresponding to the sensor in order to prevent impedance on conductors of the lead, which gradually decreases over chronic periods, from directly affecting signal transmission between the sensor and the electrical circuitry. The electrical circuitry includes a charge amplifier used for processing signals from the sensor. In some cases, the amplifier can be initially calibrated and periodically tuned so as to have consistent functioning with the sensor over chronic periods.

An actuator for an injection molding tool includes a housing, a plunger and a slide member. The housing includes an aperture extending therethrough and a first recess extending through an open end of the aperture. The plunger is slidably received in the aperture and is movable therein relative to the housing between first and second positions. The plunger may include a second recess formed therein that cooperates with the first recess to define a cavity when the plunger is in the first position. The slide member slidably engages the plunger for movement relative to the plunger between an extended position in which the slide member extends into the cavity and a retracted position in which the slide member is retracted out of the cavity.

A photoresist composition. The composition has the following: (a) one or more resin binders that include one or more acid sensitive groups and that are substantially free of phenolic groups protected by acetal or ketal groups; (b) one or more photo acid generators, that, upon exposure to a source of high energy, decompose and generate a photoacid strong enough to remove the one or more acid sensitive groups; (c) one or more ionic non-photosensitive additives including an iminium salt; and (d) one or more solvents. There is also a process for patterning relief structures on a substrate employing the photoresist composition.

A solution of a gallium phthalocyanine contains a compound of formula (1) and a gallium phthalocyanine of formula (2), H2N—CH2—R1—CH2—NH2 (1) wherein R1 represents a single bond, or a substituted or unsubstituted alkylene group having 1 to 10 main-chain carbon atoms, a substituent of the substituted alkylene group is an alkyl group having 1 to 3 carbon atoms, an alkyl group having 1 to 3 carbon atoms and being substituted with an amino group, or a hydroxy group, one of the carbon atoms in the main chain of the alkylene group may be replaced with an oxygen atom, a sulfur atom, or a bivalent group represented by the formula —NR2—, and R2 represents a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, or an alkyl group having 1 to 3 carbon atoms and being substituted with an amino group, and wherein X1 represents a chlorine atom or hydroxy group.

A technique dynamically configures and verifies routing information of broadcast networks using link state protocols in a computer network. According to the novel technique, a router within the broadcast network receives a link state protocol routing information advertisement from an advertising router, e.g., a designated router or other adjacent neighbor. The router learns of a next-hop router (“next-hop”) to reach a particular destination from the advertisement, and determines whether the next-hop is located within the same broadcast network (e.g., subnet) as the designated router. If so, the router further determines whether the next-hop is directly addressable (i.e., reachable), such as, e.g., by checking for link adjacencies to the next-hop or by sending request/reply messages (e.g., echo messages or “ping” messages) to the next-hop. In the event the next-hop for the destination is not directly addressable by the router (e.g., no adjacency or reply), the router installs a route to the destination via the designated router. Otherwise, the router installs a route to the destination via the next-hop.

A method for tracking a user's movements between network addresses can include, subsequent to a request for a (current) network address from a user, receiving the network address and an identifier for a region associated with the network address. The method can also include locating a record that contains the identifier for the region and a time that immediately precedes the request for the network address from the user. The record may further contain a prior network address. The method can further include generating an entry for a table that includes the identifier for the region, the current network address, and the prior network address. A server computer or a client computer can generate the entry. Improved accountability and improved user profile accuracy can be obtained with the method. A data processing system readable medium can comprise code that includes instructions for carrying out the method.

A bicycle gear shift control system capable of avoiding frequent gear shifting includes: a power module; a microcomputer electrically connected to the power module for allowing a cyclist to switch between the automatic gear shifting mode and a manual gear shifting mode; a gear shifting driver electrically connected to the microcomputer, substantially connected to a derailleur, and instructed by the microcomputer to drive the derailleur to perform gear shift control; and a manual shifting controller electrically connected to the microcomputer. The microcomputer has an automatic gear shifting logic whereby the microcomputer determines the timing of automatic gear shifting and performs gear shifting. The microcomputer further has a gear shifting delay logic that involves delaying for a delay time interval from commencement of gear shifting according to a gear shifting criterion and ruling out all other gear shifting commands during the delay time interval.

A method for electronically controlling a bicycle gearshift comprising at least one derailleur is disclosed, comprising the sequential steps of: a) imparting a movement on the derailleur of the gearshift until the derailleur is in an intended position;b) waiting for a predetermined time period,c) performing a check whether the derailleur is in the intended position, within a possible predetermined tolerance,d) in case said check has a negative outcome, imparting a movement on the derailleur of the gearshift until the derailleur is in the intended position. A derailleur and an electronically servo-assisted bicycle gearshift comprising control electronics comprising modules adapted to carry out the method outlined above are also disclosed.

A derailleur device, particularly a rear derailleur, includes at least one locking device for locking a chain guide at least in one locking position that is different from the starting position in relation to a movable element, and it is provided therein that the locking device includes a locking element displaceable between a passive position, in which the chain guide is released in relation to the movable element, and at least one active position, in which the chain guide is held in the at least one locking position.

The present invention relates to methodology and constructs for modifying plant architecture and enhancing plant biomass and/or sucrose yield.

The invention provides specific transgenic soybean plants, plant material and seeds, characterized in that these products harbor a stack of specific transformation events at specific locations in the soybean genome (elite event EE-GM3 and elite event EE-GM2, or elite event EE-GM3 and elite event EE-GM1). The invention also provides for methods of producing soybean plants and seeds having elite event EE-GM3 and elite event EE-GM2, or elite event EE-GM3 and elite event EE-GM1.

A method for engineering and utilizing large DNA vectors to target, via homologous recombination, and modify, in any desirable fashion, endogenous genes and chromosomal loci in eukaryotic cells. These large DNA targeting vectors for eukaryotic cells, termed LTVECs, are derived from fragments of cloned genomic DNA larger than those typically used by other approaches intended to perform homologous targeting in eukaryotic cells. Also provided is a rapid and convenient method of detecting eukaryotic cells in which the LTVEC has correctly targeted and modified the desired endogenous gene(s) or chromosomal locus (loci) as well as the use of these cells to generate organisms bearing the genetic modification.

The present invention provides compounds having the general structural formula (I), and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving abnormal or excessive fibrosis.

Herein are disclosed fluorescent dyes based around a framework for a ligand comprising a pyridyl group linked to a diaryl anilido unit. A variety of ligands based on this framework are disclosed. The ligands chelate to a BF2 center to produce the fluorescent dye. The disclosed dyes combine longer Stokes shifts (approximately 100 nm) with increased quantum yields. They are also photostable in aqueous and organic solutions for several hours. These dyes may be used in the labeling of biomolecules for bioimaging and assays. Also disclosed are methods for the synthesis of these dyes.

The present invention is concerned with a process for preparing 5-(2{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(R)-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one or a pharmaceutically acceptable salt thereof.

A knife sharpener having an angled bolster for providing predetermined sharpening angles with respect to the sharpening surface is provided. The angled bolster of the knife sharpener preferably includes two different angled surfaces for establishing at least two different predetermined sharpening angles for a cutting implement to be sharpened. The angled bolster is configured to set up the knife sharpening angle at predetermined angles with respect to the sharpening surface.

Polymeric compositions and methods for making and using the same are provided. The polymeric composition can include a first ethylene-based copolymer and a second ethylene-based copolymer. The first ethylene-based copolymer can have a weight percent of ethylene-derived units based on a weight of the polymeric composition (EA) ranging from about 35 wt % to about 52 wt % and a weight-average molecular weight (MwA) of less than or equal to 130,000. The second ethylene-based copolymer can have a weight percent of ethylene-derived units based on the weight of the polymeric composition (EB) ranging from about 65 wt % to about 85 wt % and a weight-average molecular weight (MwB) of less than 130,000.

A composition is provided for use as a friction modifier for an automatic transmission, which comprises a condensation product of a hydroxypolycarbox-ylic acid, such as 2,3-di-hydroxybutanedioic acid or 2-hydroxybutanedioic acid, with an N,N-di(hydrocarbyl)alkylenediamine, where each hydrocarbyl group contains 1 to 22 carbon atoms, provided that the total number of carbon atoms in the two hydrocarbyl groups is at least about 9, and the alkylene group contains 2 to 4 carbon atoms.

Disclosed are rheology modifiers comprising compositionally disperse polymeric compositions and/or crystallinity disperse polymeric compositions that may be useful in modifying the rheological properties of lubrication fluids, and methods for making such compositions. The compositionally disperse polymeric composition are formed from at least two discrete compositions of ethylene copolymers. The crystallinity disperse polymeric composition are formed from ethylene copolymers having at least two discrete values of residual crystallinity.

A device and method for adjusting the magnetic strength of a magnetic end effector for lift systems is described. The magnetic end effector is capable of lifting discriminate payloads by selectively varying the strength of the magnetic forces output by the magnetic end effector. An actuator can be operatively coupled to the variable strength magnet end effector, wherein the actuator is selectively actuatable to control the adjustment of the variable strength magnet. The actuator may also be configured to maintain the variable strength magnet at a desired magnetic force output strength once achieved for any given amount of time.

The present invention refers to a method for adjusting power levels of channels (15) in an optical link (7) of an optical network comprising at least one optical amplifier (9) wherein the power distribution among the channels (15) of the optical link (7) is achieved in function of: target power levels based on the features of corresponding connections and of link physical features,total available power in said at least one amplifier (9),features of control means allowing the power distribution, and wherein for a channel corresponding to a connection having a higher vulnerability characterizing parameter, the tolerated difference between an actual channel power level and the target power level is lower than for a channel corresponding to a connection having a lower vulnerability characterizing parameter.

The device identification apparatus includes: a remote controller signal detecting section for detecting an optical signal from a remote controller; a receiving section for receiving the optical signal from the remote controller; a signal decryption section for decrypting the optical signal received by the receiving section; and a transmitting section for transmitting a device identification signal when the optical signal is a device selecting signal, and configured such that operations of the receiving section, the signal decryption section, and the transmitting section are started in response to a detecting signal of the remote controller signal detecting section, thereby realizing a device identification apparatus in which power consumption during standby is minimized.

A laminated body composed of a holding member and an inner cylinder is arranged between a heat generation element, which is electrically energized to generate heat, and a case which covers the heat generation element, and the inner cylinder has an upstream side end portion extended to a more upstream side than an upstream side end face of said heat generation element and an upstream side end face of said holding member to form an extension portion, which is formed with a protruding portion protruding to an inner side in a diametrical direction. A flow of an exhaust gas, which flows backwards after colliding with the heat generation element, will be obstructed by said protruding portion. As a result, the backflow exhaust gas stops flowing into a gap between the case and the inner cylinder.

The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.

A transmissive diffraction grating includes a polarization conversion layer, a first diffractive layer disposed on one surface side of the polarization conversion layer, and a second diffractive layer disposed on the other surface side of the polarization conversion layer. Both the first diffractive layer and the second diffractive layer include refractive index modulation structures arranged with a period P in a first direction, and diffraction efficiency for a TE polarized light component is higher than a diffraction efficiency for a TM polarized light component.

The present disclosure relates to an improved device and methods for adapting to a laser diffraction apparatus used for measuring particle size distribution and density of the plume of a powder composition emitted from a dry powder inhaler.

Within machine vision, object movement is often estimated by applying image evaluation techniques to visible light images, utilizing techniques such as perspective and parallax. However, the precision of such techniques may be limited due to visual distortions in the images, such as glare and shadows. Instead, lidar data may be available (e.g., for object avoidance in automated navigation), and may serve as a high-precision data source for such determinations. Respective lidar points of a lidar point cloud may be mapped to voxels of a three-dimensional voxel space, and voxel clusters may be identified as objects. The movement of the lidar points may be classified over time, and the respective objects may be classified as moving or stationary based on the classification of the lidar points associated with the object. This classification may yield precise results, because voxels in three-dimensional voxel space present clearly differentiable statuses when evaluated over time.

A Low Forward Voltage Rectifier (LFVR) circuit includes a bipolar transistor, a parallel diode, and a capacitive current splitting network. The LFVR circuit, when it is performing a rectifying function, conducts the forward current from a first node to a second node provided that the voltage from the first node to the second node is adequately positive. The capacitive current splitting network causes a portion of the forward current to be a base current of the bipolar transistor, thereby biasing the transistor so that the forward current experiences a low forward voltage drop across the transistor. The LFVR circuit sees use in as a rectifier in many different types of switching power converters, including in flyback, Cuk, SEPIC, boost, buck-boost, PFC, half-bridge resonant, and full-bridge resonant converters. Due to the low forward voltage drop across the LFVR, converter efficiency is improved.

A high voltage full wave rectifier and doubler circuit having complementary serially connected low voltage MOSFET stacks to provide high voltage capability. The state of the MOSFETs in the MOSFET stacks is controlled by means of resistors coupled between the circuit's outputs and a time varying input signal. The resistance values of the resistors are selected to maintain operation of the stacked MOSFETs below their breakdown voltages.

A controller for a power converter and method of operating the same employable with a bridge rectifier having first and second synchronous rectifier switches. In one embodiment, the controller includes an amplifier configured to enable a turn-on delay for the first synchronous rectifier switch. The controller also includes a discharge switch having first and second switched terminals coupled to gate and source terminals, respectively, of the first synchronous rectifier switch and configured to discharge a gate-to-source capacitance of the first synchronous rectifier switch to enable a turn off thereof.

An apparatus is provided for mounting to a support for modifying an ankle-foot orthosis. The apparatus comprises a tooling device having a plurality of holes spaced over an outer surface of the tooling device. The tooling device includes a first portion having a longitudinal axis, and a second portion integral with the first portion and having a longitudinal axis substantially perpendicular to the longitudinal axis of the first portion. The second portion of the tooling device defines an opening for receiving the support. A peg is configured to be inserted into one of more holes of the tooling device. The peg comprises a body portion and a post depending from the body portion and configured to be received in the holes in the outer surface of the tooling device. In one embodiment, the body portion of the peg has a convex outer surface.

A wound dressing including a hydrophilic layer and a hydrophobic layer is described. The hydrophilic layer absorbs exudate from a wound and the hydrophobic layer absorbs the exudate from the hydrophilic layer and traps the exudate. Because the hydrophilic layer is used adjacent to the wound, the exudate is readily absorbed thereby reducing the risk of maceration and infection of the wound tissue by the exudate. The hydrophobic layer receives the absorbed exudate from the hydrophilic layer and traps the exudate through an interaction that in turn prevents lateral diffusion of the exudate through the bandage to healthy portions of the skin. The hydrophilic and hydrophobic layers are fabricated from polymer fibers that can be spun to include components that facilitate wound healing, such as poly(hexamethylene biguanide) and/or hyaluronic acid.

The present invention relates to a composite of a porous substrate and one-dimensional nanomaterial, which is manufactured by a hydrothermal method. The method for manufacturing the composite of the present invention is simple and low-cost, and the one-dimensional nanomaterial is homogeneously distributed on the porous substrate with tight binding at the interface. The present invention also relates to a surface-modified composite and a method for preparing the same. The composite of the present invention which is hydrophobically modified at the surface can adsorb organic solvents such as toluene, dichlorobenzene, petroleum ether and the like, and greases such as gasoline, lubricating oil, motor oil, crude oil and the like, with a weight adsorption ratio of >10.

A method for preparing lignin graft copolymer comprising: reacting lignocellulosic materials with an acrylic compound by bulk condensation under nitrogen atmosphere in the presence of a non-oxidizing strong organic acid as catalyst; separating the reaction mixture to obtain a solid phase mainly containing lignocellulosic materials and a liquid phase containing lignin graft copolymer and unreacted acrylic compound; and removing solvent from the liquid phase to obtain the lignin graft copolymer.

A polymer composition suitable for wood treatment or binding comprises a reaction product of at least a polyol and at least a crosslinking agent. The crosslinking agent has at least 2 carboxylic acid groups per molecule. A wood product comprising a wood substrate and a polymer composition as well as a wood treatment process are also disclosed.

Biomaterials that support cell attachment and growth are provided. In one aspect, biomaterials are provided comprising a first polymer matrix comprising reactive amino moieties and a second polymer matrix that interpenetrates with the first polymer matrix, where the second polymer matrix comprises a poly(alkylene oxide) comprising two or more alkylene oxide oligomers joined by gamma-thioether carbonyl linkages. In another aspect, biomaterials are provided comprising at least one biopolymer comprising amino groups, thiol groups, and bifunctional modifiers connecting at least some of the amino groups to at least some of the thiol groups; and at least one poly(alkylene oxide) cross-linked to at least two thiol groups of the biopolymer. The biomaterials may further comprise a pharmacologically active agent or cells. Methods of administering such biomaterials to a patient in need thereof are also provided.

An accommodating intraocular lens (AIOL) includes an optic adapted to produce a trapezoidal phase shift and a plurality of haptics. Each haptic extends from a haptic-optic junction to at least one transverse arm contacting a capsular bag of the eye, and each haptic has sufficient length and rigidity to stretch a capsular bag of the eye to contact ciliary muscles of the eye. The haptic-optic junctions vault the optic forward relative to the haptics and compression of the haptics by the ciliary muscles moves the anterior optic forward. A combined accommodative power produced by the motion of the anterior optic and the trapezoidal phase shift is at least 0.5 Diopters.

The present invention relates to an image-based, patient-specific medical spinal surgery technique and to a spinal prosthesis used in the surgery, and particularly, to an image-based, patient-specific medical spinal surgery technique and to a spinal prosthesis which are intended to solve a problem of damage to a spine caused by installing a spinal prosthesis used in spinal surgery, by introducing an image of a patient to manufacture an insertable spinal prosthesis that is customized for a shape of a spine of an individual patient in a polymer-based material.

The present invention relates to a rapid, sensitive, simple, and cost-effective spectrophotometric method of detecting and quantifying mycolic acid in a mycolic acid-fuschin dye complex with absorbance maxima ranging between 490-500 nm in the presence of various test compounds, for screening mycolic acid biosynthesis inhibitors useful as anti-microbial agents and a diagnostic kit thereof comprising basic fuschin dye in the concentration ranging between 0.1-1.0 gm/100 ml, phenol and 95% ethanol in the ratio ranging between 1:4 to 2:1 (v/v), and phenol and distilled water in the ratio ranging between 1:14 to 1:25.