program Nigerian military, Reuters at odds over reports on alleged mass abortion program By www.voanews.com Published On :: Mon, 11 Nov 2024 17:25:20 -0500 Abuja, Nigeria — The Nigerian military welcomed a report by a human rights group that found “no evidence” the military secretly carried out thousands of illegal abortions as part of its fight against Islamist insurgency. The Reuters news agency says it stands by its three reports in 2022 which lodged the allegations. In a statement over the weekend, Nigerian Defense Chief General Christopher Musa praised the report by the seven-member investigative panel set up by the National Human Rights Commission of Nigeria. Musa said no amount of false accusations will distract the armed forces from defending Nigeria's integrity. On Friday, the Nigerian investigative panel said it found “no evidence” that the Nigerian military secretly carried out illegal abortions or had such a policy in its operations against terror groups. The panel's probe lasted 18 months and was based on 199 testimonies from witnesses including Musa, who was leading the counterinsurgency campaign at the time. In December 2022, Reuters news agency published three reports alleging that the Nigerian military ran a mass abortion program for victims of the long-running Boko Haram insurgency and massacred children in the northeast. The report alleged that the military had carried out more than 10,000 abortions since 2013. "The panel made its findings meticulously on each of the issues," said Hillary Ogbonna, secretary to the investigative panel. "For the abortion assault, the panel did not find evidence that the Nigerian armed forces committed a systematic, secret or policy-driven abortion in the northeast to the tune of 10,000 abortions." The committee, however, agreed with a Reuters report alleging the military committed human rights violations, including infanticide, during a military operation in June 2016. "The panel found the military culpable of infanticide and the killing of community members in the village of Abisare in Borno State. We've received witness testimonies including those of the survivors and relations of the deceased," Ogbonna said. Responding to the panel's report, Reuters said it stands by its investigation, stating that it satisfied their standards for independence, accuracy and impartiality. On Monday, a Nigerian human rights group, Women Concerns, called on Reuters to withdraw the report and apologize to the Nigerian military. But security analyst Chidi Omeje said when there's disagreement between two parties, an independent committee can be set up to review the reports. "I don't know how the human rights commission went about the investigation. I really cannot say whether it was a thorough job done or whether there was some influence somewhere. Maybe some other independent organizations should be able to wade in," Omeje said. "I know that [the] human rights commission, even though I'm not trying to doubt their integrity, it has some allegiance to the government because it's a government agency." Years of military offensives against terror groups in Nigeria have been embroiled in allegations of human rights violations. Soldiers have been accused of mistreating civilians and carrying out extrajudicial killings. "It tells you how it is very difficult to maintain or stick to that professionalism if you're dealing with this kind of asymmetric warfare. Sometimes it is difficult to distinguish who the adversaries are," Omeje said. Recently, the military launched a public relations campaign, seeking to repair its reputation. Full Article Africa
program Government Programs Have Begun to Reduce Maternal Deaths in Lao PDR: Now What Comes Next? By www.eastwestcenter.org Published On :: Tue, 23 Oct 2018 21:52:03 +0000 Government Programs Have Begun to Reduce Maternal Deaths in Lao PDR: Now What Comes Next? Government Programs Have Begun to Reduce Maternal Deaths in Lao PDR: Now What Comes Next? Anonymous (not verified) Tue, 10/23/2018 - 11:52 Mar 30, 2018 Mar 30, 2018 Gender Equality Gender Equality Public Health Public Health Social Issues Social Issues Laos Laos East-West Wire Tagline News, Commentary, and Analysis Home EWC Feeds East-West Wire The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here. For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists. Explore search All Programs All Regions All Topics Release Date Filters Reset filters East-West Wire Tagline News, Commentary, and Analysis Home EWC Feeds East-West Wire The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here. For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists. Explore search All Programs All Regions All Topics Release Date Filters Reset filters Full Article
program Head of UN nuclear watchdog: 'Dire straits dynamic' with Iran's nuclear program amid Mideast wars By www.voanews.com Published On :: Tue, 12 Nov 2024 13:54:27 -0500 BAKU, Azerbaijan — The head of the United Nations' nuclear watchdog said Tuesday he's hopeful that meetings this week with Iranian officials, including the country's new president, can lead to a breakthrough in monitoring the country's nuclear program, a longstanding issue that has gained new urgency as Israel has twice struck Iran amid rising tensions in the Middle East. Rafael Mariano Grossi, director general of the International Atomic Energy Agency, will travel to Iran on Wednesday to meet for the first time with President Masoud Pezeshkian, who was elected in July. Grossi said he hopes to build on positive discussions he had with Iranian Foreign Minister Abbas Araghchi during the U.N. General Assembly in September. "We have a problem that we need to solve," Grossi said in an interview at the U.N. climate conference in Azerbaijan. "That is this gap, this lack of confidence, which we should not allow to grow into a self-fulfilling prophecy of using nuclear facilities as targets." He added: "There has been a bit of a dire straits dynamic with Iran that we want to go beyond." Iran is rapidly advancing its atomic program while increasing stockpiles of uranium enriched to near weapons-grade levels, all in defiance of international demands, according to the IAEA. Iran says its program is for energy purposes, not to build weapons. Grossi's visit comes as Israel and Iran have traded missile attacks in recent months after more than a year of war in Gaza, which is governed by Hamas, a group supported by Iran. Grossi noted that international law prohibits the attack of nuclear facilities and "it's obvious that is something that can have radiological consequences." The Biden administration said last month that it had won assurances from Israel that it would not attack nuclear or oil sites. A 2015 nuclear agreement between Iran and world powers put limits on Iran's nuclear program, which the West fears could be used to make nuclear weapons. The deal included the lifting of economic sanctions on Iran. But that deal collapsed after Donald Trump's administration in 2018 pulled the United States from it. That led Iran to abandon all limits put on its program and enrich uranium to up to 60% purity. When asked if the IAEA feared Iran may be developing a bomb, Grossi said he didn't "have any information that would sustain that." He added that inspectors' job was not to "judge intentions," but rather verify that what Iran says about its nuclear program was true. Trump's reelection last week raises questions about whether and how the incoming administration and Iran may engage. Grossi said he had worked with the first Trump administration, which he said engaged in "seamless, professional work," and looked forward to looking with Trump's second administration. "Circumstances have changed in that the problem has grown bigger than it was," said Grossi. "The problem of not finding a solution." Full Article Iran Middle East
program ADB-DROP Program By www.eastwestcenter.org Published On :: Fri, 14 Oct 2022 00:24:49 +0000 ADB-DROP Program fairfieb Thu, 10/13/2022 - 14:24 Mar 7, 2023 Pacific Education & Exchange Full Article
program Congressional Staff Program on Korea Application By www.eastwestcenter.org Published On :: Mon, 17 Oct 2022 18:09:53 +0000 Congressional Staff Program on Korea Application lynchk Mon, 10/17/2022 - 08:09 Mar 26, 2023 North Korea South Korea Economics Environment & Climate Governance Leadership Politics & International Relations Science & Technology Full Article
program Professional Fellows Program for Young Economic Empowerment Leaders By www.eastwestcenter.org Published On :: Fri, 03 Mar 2023 20:41:55 +0000 Professional Fellows Program for Young Economic Empowerment Leaders kroekers Fri, 03/03/2023 - 10:41 Aug 7, 2023 Pacific Economics Education & Exchange Leadership Full Article
program POSCO Visiting Fellowship Program By www.eastwestcenter.org Published On :: Wed, 30 Nov 2022 07:47:15 +0000 POSCO Visiting Fellowship Program laupolaj Tue, 11/29/2022 - 21:47 Oct 31, 2023 North Korea South Korea Full Article
program Congressional Program on US-Japan Relations and the Indo-Pacific Application By www.eastwestcenter.org Published On :: Wed, 30 Nov 2022 16:49:07 +0000 Congressional Program on US-Japan Relations and the Indo-Pacific Application lynchk Wed, 11/30/2022 - 06:49 Dec 5, 2023 Japan Governance Leadership Politics & International Relations Full Article
program Asia Matters for America Governors' Staff Program By www.eastwestcenter.org Published On :: Wed, 02 Aug 2023 17:48:03 +0000 Asia Matters for America Governors' Staff Program hulla Wed, 08/02/2023 - 07:48 Aug 2, 2023 East Asia Japan South Korea Leadership Full Article
program Congressional Staff Program on Australia (CSPAUS) Application By www.eastwestcenter.org Published On :: Mon, 07 Aug 2023 16:47:29 +0000 Congressional Staff Program on Australia (CSPAUS) Application jacksonl1 Mon, 08/07/2023 - 06:47 Aug 7, 2023 Australia Politics & International Relations Full Article
program Advanced Leadership Program By www.eastwestcenter.org Published On :: Wed, 27 Mar 2024 23:00:32 +0000 Advanced Leadership Program tokitac Wed, 03/27/2024 - 13:00 Apr 1, 2024 Education & Exchange Leadership Full Article
program Asian Development Bank-Japan Scholarship Program By www.eastwestcenter.org Published On :: Fri, 14 Oct 2022 00:44:54 +0000 Asian Development Bank-Japan Scholarship Program fairfieb Thu, 10/13/2022 - 14:44 Aug 2, 2024 West Asia Education & Exchange Full Article
program Asia Pacific Leadership Program By www.eastwestcenter.org Published On :: Thu, 26 Aug 2021 01:17:01 +0000 Asia Pacific Leadership Program tokitac Wed, 08/25/2021 - 15:17 Sep 1, 2024 Full Article
program East-West Center Student Affiliate Program By www.eastwestcenter.org Published On :: Fri, 23 Aug 2019 23:30:16 +0000 East-West Center Student Affiliate Program fairfieb Fri, 08/23/2019 - 13:30 Mar 1, 2024 Education & Exchange Full Article
program East-West Center in Washington Young Professionals Program By www.eastwestcenter.org Published On :: Fri, 14 Oct 2022 18:32:38 +0000 East-West Center in Washington Young Professionals Program hulla Fri, 10/14/2022 - 08:32 Sep 6, 2024 Leadership Full Article
program 2024 Pacific Islands Leadership Program with Taiwan (PILP) By www.eastwestcenter.org Published On :: Fri, 19 Jan 2024 19:50:14 +0000 2024 Pacific Islands Leadership Program with Taiwan (PILP) concepcl Fri, 01/19/2024 - 09:50 Jan 22, 2024 Pacific Leadership Full Article
program US South Pacific Scholarship Program By www.eastwestcenter.org Published On :: Fri, 14 Oct 2022 00:53:24 +0000 US South Pacific Scholarship Program fairfieb Thu, 10/13/2022 - 14:53 Aug 2, 2024 Pacific Education & Exchange Full Article
program Girl Effect drives social change through innovative programmes for young girls in South Africa By www.iol.co.za Published On :: Mon, 11 Nov 2024 11:41:32 GMT Full Article
program El programa de la oración A By feeds.gracia.org Published On :: Tue, 09 Jan 2024 00:00:00 PST La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.Click the icon below to listen. Full Article
program El programa de la oración B By feeds.gracia.org Published On :: Wed, 10 Jan 2024 00:00:00 PST La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.Click the icon below to listen. Full Article
program 23rd Ministerial Conference of the Central Asia Regional Economic Cooperation Program - Masatsugu Asakawa By www.adb.org Published On :: 2024-11-08 Keynote address by Masatsugu Asakawa, President, Asian Development Bank, at the 23rd Ministerial Conference of the Central Asia Regional Economic Cooperation Program, 8 November 2024 Full Article
program Senior Ombuds Programs Officer By www.adb.org Published On :: 2024-10-16 ADB has a vacancy for the position of Senior Ombuds Programs Officer in the Office of the Ombudsperson. The deadline for submitting applications is on 13-NOV-2024. Full Article
program 54110d programming user guide By english.al-akhbar.com Published On :: 54110d programming user guide Full Article
program 11c programmer manual By english.al-akhbar.com Published On :: 11c programmer manual Full Article
program 11757b programming user guide By english.al-akhbar.com Published On :: 11757b programming user guide Full Article
program Loan No. 2972-PAK: Power Distribution Enhancement Investment Program, Tranche-III [ADB-TRANCHE-III-MEPCO-01] By www.adb.org Published On :: Full Article
program Loan No. 2924-IND: Uttarakhand Power Sector Investment Program - Project 4 [ICB No. 3-P/ADB/PTCUL/2012-13] By www.adb.org Published On :: Full Article
program Loan No. 3411-AZE: Water Supply and Sanitation Investment Program - Tranche 4 [MFF42408-044-T4-ICB-1.02] By www.adb.org Published On :: Full Article
program Loan No. 42486-IND: Madhya Pradesh Urban Services Improvement Program [MPUSIP 6D REBIDDING] By www.adb.org Published On :: Full Article
program Loan Nos. 3076/3077-PNG: Highland Region Road Improvement Investment Program [CSTB No. 2946] By www.adb.org Published On :: Full Article
program Loan No. 42401-AZE: Power Distribution Enhancement Investment Program - Tranche 1 [AI/ADB-10.1 and AI/ADB-10.2] By www.adb.org Published On :: Full Article
program Loan No. 3203-PAK: Power Transmission Enhancement Investment Program Tranche 4 [ADB-79-2015] EXTENDED By www.adb.org Published On :: Full Article
program Loan No. 2972-PAK: Power Distribution Enhancement Investment Program - Tranche 3 [LESCO-10-2013] By www.adb.org Published On :: Full Article
program Loan No. 2830-IND: Madhya Pradesh Energy Efficiency Improvement Investment Program – Tranche 2 [MD / WZ / 06 / PUR / ADB /993] By www.adb.org Published On :: Full Article
program Climate and Disaster Resilience Enhancement Program (Subprogram 1) By www.adb.org Published On :: 2024-10-29 The proposed program will support the enhancement of Pakistan's resilience to disasters triggered by natural hazards and the impacts of climate change. Through an integrated approach, the program will support (i) strengthened institutional capacity for strategy, planning, and response; (ii) increased investment in disaster risk reduction (DRR) and climate resilience; and (iii) enhanced disaster risk financing (DRF) using a risk-layered approach. Full Article
program Fiscal Sustainability and Financial Markets Development Program (Subprogram 2) By www.adb.org Published On :: 2024-10-31 Full Article
program Health Care Quality Improvement Program By www.adb.org Published On :: 2024-11-06 The program aims to improve the quality of health care as stipulated in the Government Program, 2021-2026, Health Sector Strategy 2023-2026, the UHI Concept Paper, and the Quality of Care Strategy 2022-2026. Full Article
program Seismic Safety Improvement Program 3 By www.adb.org Published On :: 2025 The Republic of Armenia is located at the intersection of major tectonic faults, making it highly prone to seismic activity. The devastation of the 1988 Spitak earthquake claimed about 25,000 lives, including 6,000 school children; left 517,000 people homeless, destroyed 190 schools and many urban infrastructures; and incurred direct economic losses of $15 billion-$20 billion. The recent 7.8-magnitude earthquake in neighboring Trkiye and Syria in 2023 is a wake-up call for Armenia, posing a significant threat to the country. rkiye and Syria in 2023 is a wake-up call for Armenia, posing a significant threat to the country. Full Article
program Resilient Amu Darya River Basin Sector Development Program By www.adb.org Published On :: 2025 The proposed project will undertake a long-term and strategic approach to deliver climate adaptive solutions for water resources management in the Amu Darya River Basins in Uzbekistan. Predicted climate change impacts include increased temperatures, increased frequency and severity of extreme events such as floods and droughts, and a reduction of water availability and increased variability of water flows in the major river basins. Decreasing availability and increased water requirements by different sectors are leading to a growing seasonal and absolute supply-demand gap. Full Article
program MFF: Green and Resilience Financing Facility Investment Program By www.adb.org Published On :: 2026 The proposed program is a large-scale transformative and integrated initiative addressing the constraints. It aims to bridge the financing, capacity, institutional, and technical gaps in implementing the NAP and adaptation measures mentioned in the NDC and GRID while promoting mitigation, biodiversity, air pollution, and food security as co-benefits. Full Article
program Walking School Bus Programs Take Off By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: Walking School Bus Programs Take OffCategory: Health NewsCreated: 8/23/2011 11:01:00 AMLast Editorial Review: 8/23/2011 12:00:00 AM Full Article
program 'Pretend Mommy' Program Doesn't Deter Teen Pregnancy By www.medicinenet.com Published On :: Mon, 29 Aug 2022 00:00:00 PDT Title: 'Pretend Mommy' Program Doesn't Deter Teen PregnancyCategory: Health NewsCreated: 8/25/2016 12:00:00 AMLast Editorial Review: 8/26/2016 12:00:00 AM Full Article
program Implementation of an Opt-Out Outpatient HIV Screening Program By www.jabfm.org Published On :: 2024-10-25T09:26:14-07:00 Background: Screening rates for Human Immunodeficiency Virus (HIV) remain low despite guidelines by both the CDC and USPSTF recommending that all adolescents and adults be screened at least once. The aim of this quality improvement study was to increase HIV screening among eligible patients. Methods: This quality improvement study assessed the impact of interventions to increase HIV screening in an outpatient population at a large urban safety-net hospital. Outcomes were compared from the preintervention (December 2020 to November 2021) to postintervention years (December 2021 to November 2022). Stepwise electronic alerts to prompt HIV screening paired with provider financial incentives were implemented. The proportion of eligible individuals screened for HIV were compared after intervention implementation. Results: Average monthly HIV screening increased from 506 ± 97 to 2484 ± 663 between the pre- and postintervention periods, correlating to a 5.1-fold increase in screening (7.8% to 39.8%, P < .01). Increases were seen across all ages, and those aged 55 to 64 and 65+ had the highest relative increase in screening at 7.5 and 9.3-fold, respectively (P < .01). Screening rates increased for Hispanics (7.9% preintervention vs 43.6% postintervention, P < .01). In the pre- and postintervention periods, 41 patients with new HIV diagnoses were identified (13 preintervention and 28 postintervention) and 85.4% were linked to care within 30 days. Conclusions: Stepwise interventions targeted at primary care clinicians are an effective way to increase HIV screening rates, particularly in older demographics. Earlier HIV diagnosis coupled with linkage to care is an important strategy in ending the HIV epidemic. Full Article
program Perspectives on Using Race in Pulmonary Function Testing: A National Survey of Fellows and Program Directors By rc.rcjournal.com Published On :: 2024-10-25T05:44:12-07:00 BACKGROUND:Pulmonary function tests (PFTs) have historically used race-specific prediction equations. The recent American Thoracic Society guidelines recommend the use of a race-neutral approach in prediction equations. There are limited studies centering the opinions of practicing pulmonologists on the use of race in spirometry. Provider opinion will impact adoption of the new guideline. The aim of this study was to ascertain the beliefs of academic pulmonary and critical care providers regarding the use of race as a variable in spirometry prediction equations.METHODS:We report data from 151 open-ended responses from a voluntary, nationwide survey (distributed by the Association of Pulmonary Critical Care Medicine Program Directors) of academic pulmonary and critical care providers regarding the use of race in PFT prediction equations. Responses were coded using inductive and deductive methods, and a thematic content analysis was conducted.RESULTS:There was a balanced distribution of opinions among respondents supporting, opposing, or being unsure about the incorporation of race in spirometry prediction equations. Responses demonstrated a wide array of understanding related to the concept and definition of race and its relationship to physiology.CONCLUSIONS:There was no consensus among providers regarding the use of race in spirometry prediction equations. Concepts of race having biologic implications persist among pulmonary providers and will likely affect the uptake of the Global Lung Function Initiative per the American Thoracic Society guidelines. Full Article
program Promoting Male Involvement in Family Planning: Insights From the No-Scalpel Vasectomy Program of Davao City, Philippines By ghspjournal.org Published On :: 2024-10-29T12:28:39-07:00 ABSTRACTDespite global consensus on the importance of male involvement in family planning, disparities persist in low- and middle-income countries, where women continue to bear the responsibility for these initiatives. The Philippines, with a high fertility rate and unmet family planning needs, exemplifies this challenge. We present the experiences and lessons learned from implementing the no-scalpel vasectomy (NSV) program in Davao City, showcasing its potential for increasing male engagement in family planning decisions. Launched in 2008, the program aimed to address gender disparity by promoting NSV as a safe and effective contraceptive alternative to female-centric methods. Through the use of culturally sensitive information campaigns and couple-focused counseling, the program challenged traditional notions of masculinity and encouraged shared decision-making. Strong local government commitment and public-private partnerships played key roles in driving the program’s success. Results showed an average annual increase of 80% in NSV clients over the past 3 years compared to before the COVID-19 pandemic, underscoring its effectiveness. The program presents a compelling intervention model for similar initiatives, highlighting how overcoming cultural barriers, infrastructure limitations, and budgetary constraints through policy advocacy, strategic partnerships, and tailored approaches can significantly boost male involvement in family planning and improve reproductive health outcomes within communities. Full Article
program Can the International Conference on Population and Development Programme of Action and Cairo Consensus Normalize the Discourse on Population? By ghspjournal.org Published On :: 2024-10-29T12:28:39-07:00 Full Article
program Strengthening Capacity for Tailored Immunization Programs Using Adult Learning Principles: A Case Study from Nigeria By ghspjournal.org Published On :: 2024-10-29T12:28:39-07:00 ABSTRACTIntroduction: Nigeria has the highest number of children who have not received any vaccines in Africa. The training-of-trainers (TOT) model used to train program managers (PMs) and health care workers (HCWs) is ineffective for adult learning and limits immunization programs’ success. We incorporated adult learning principles (ALPs) in designing and delivering TOT for immunization PMs and HCWs to use data to engage communities for tailored immunization strategies.Methods: Our study was implemented in 3 local government areas (LGAs) of the Federal Capital Territory, Nigeria. A training curriculum was developed, integrating ALPs and technical and operational content based on best practices in delivering immunization training and the training needs assessment findings. State PMs (n=10), LGA PMs (n=30), and HCWs (n=42) were trained on the human-centered design for tailoring immunization programs (HCD-TIP) approaches using ALPs. We used interviews and surveys with purposively and conveniently sampled PMs and HCWs, respectively, and observations to assess participants’ satisfaction, knowledge and competence, behavior changes, and results. The interviews were analyzed thematically, and surveys were statistically.Results: There was a high level of satisfaction with the training among LGA PMs (100%), state PMs (91%), and HCWs (85%), with significant knowledge and competence improvements post-training (P<.001). The trained participants conducted 2 HCD sessions with 24 undervaccinated communities and co-designed 24 prototype solutions for testing. Results showed increased coverage of the pentavalent vaccine first dose (54%) and third dose (188%) across 12 participating communities. Improved community colaboration, communication skills, and data-driven approaches were the most cited behavior changes in practice.Conclusion: The application of ALPs in training, use of HCD-TIP approaches and tools, and supportive supervision enhanced PMs’ and HCWs’ capacity for tailored interventions. Countries should consider adopting a holistic approach that focuses on using these approaches in immunization programs to strengthen the health system for equitable vaccine coverage. Full Article
program Efficacy and Toxicity of [177Lu]Lu-PSMA-617 for Metastatic Castration-Resistant Prostate Cancer: Results from the U.S. Expanded-Access Program and Comparisons with Phase 3 VISION Data By jnm.snmjournals.org Published On :: 2024-11-01T04:25:31-07:00 The phase 3 VISION trial demonstrated that [177Lu]Lu-PSMA-617 prolonged progression-free survival and overall survival (OS) in prostate-specific membrane antigen [PSMA]–positive metastatic castration-resistant prostate cancer (mCRPC) patients who progressed on taxane-based chemotherapy and androgen receptor–signaling inhibitors (ARSIs). The U.S. expanded-access program (EAP; NCT04825652) was opened to provide access to [177Lu]Lu-PSMA-617 for eligible patients until regulatory approval was obtained. This study aimed to evaluate the efficacy and safety profile of [177Lu]Lu-PSMA-617 within the EAP and compare the results with those from the VISION trial. Methods: Patients enrolled in the EAP at 4 institutions in the United States with available toxicity and outcome data were included. Outcome measures included OS, a prostate-specific antigen (PSA) response rate (RR) of at least 50%, and incidences of toxicity according to Common Terminology Criteria for Adverse Events version 5.0. Differences in baseline characteristics, outcome data, and toxicity between the EAP and VISION were evaluated using t testing of proportions and survival analyses. Results: In total, 117 patients with mCRPC who received [177Lu]Lu-PSMA-617 within the EAP between May 2021 and March 2022 were eligible and included in this analysis. Patients enrolled in the EAP were more heavily pretreated with ARSI (≥2 ARSI regimens: 70% vs. 46%; P < 0.001) and had worse performance status at baseline (Eastern Cooperative Oncology Group score ≥ 2: 19% vs. 7%; P < 0.001) than VISION patients. EAP and VISION patients had similar levels of grade 3 or higher anemia (18% vs. 13%; P = 0.15), thrombocytopenia (13% vs. 8%; P = 0.13), and neutropenia (3% vs. 3%; P = 0.85) and similar PSA RRs (42% vs. 46%; P = 0.50) and OS (median: 15.1 vs. 15.3 mo; P > 0.05). Conclusion: Patients with PSMA-positive mCRPC who received [177Lu]Lu-PSMA-617 within the EAP were later in their disease trajectory than VISION patients. Patients enrolled in the EAP achieved similar PSA RRs and OS and had a safety profile similar to that of the VISION trial patients. Full Article
program DayZ creator reveals a "Kerbal Space Program killer" with kittens and challenges license owners to sue him By www.rockpapershotgun.com Published On :: Thu, 31 Oct 2024 12:35:09 +0000 Stationeers and Icarus developers RocketWerkz are making a spiritual successor to beloved space sim Kerbal Space Program, which is currently titled "Kitten Space Agency" in a flagrant display of adherence to wholesome internet trends. It's based on an actual Kerbal Space Program 2 pitch the studio threw at Take-Two subsidiary Private Division back in the day. RocketWerkz CEO and original DayZ creator Dean Hall has hired several former KSP and KSP2 developers to work on the game, and is describing it on social media as a "KSP killer". Read more Full Article Private Division Indie MMORPG Third person Action Adventure Single Player Mod Xbox One PS4 Simulation Bohemia Interactive Kerbal Space Program 2 Dean "Rocket" Hall Multiplayer Competitive Multiplayer Cooperative PC First person DayZ RPG Shooter
program Stranded ISS astronauts reveal the US space programme is not in crisis By www.newscientist.com Published On :: Wed, 28 Aug 2024 21:00:46 +0100 The failure of Boeing's Starliner capsule has left two astronauts stuck in space for months – but also proved how private spaceflight can go right Full Article