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New Guidelines Suggest HIV Screening for All Adults

Title: New Guidelines Suggest HIV Screening for All Adults
Category: Health News
Created: 4/29/2013 6:36:00 PM
Last Editorial Review: 4/30/2013 12:00:00 AM




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Urologists' Group Issues Updated Guidelines on PSA Test

Title: Urologists' Group Issues Updated Guidelines on PSA Test
Category: Health News
Created: 5/3/2013 12:35:00 PM
Last Editorial Review: 5/3/2013 12:00:00 AM




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Trampolines Linked to More Than 1 Million ER Visits Over a Decade

Title: Trampolines Linked to More Than 1 Million ER Visits Over a Decade
Category: Health News
Created: 5/2/2014 12:35:00 PM
Last Editorial Review: 5/2/2014 12:00:00 AM




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Pediatricians Issue New Guidelines for Hospital Release of Newborns

Title: Pediatricians Issue New Guidelines for Hospital Release of Newborns
Category: Health News
Created: 4/27/2015 12:00:00 AM
Last Editorial Review: 4/27/2015 12:00:00 AM




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Study Challenges Salt Guidelines for Kids

Title: Study Challenges Salt Guidelines for Kids
Category: Health News
Created: 4/27/2015 12:00:00 AM
Last Editorial Review: 4/28/2015 12:00:00 AM




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New Guidelines Issued on Breast, Genital Plastic Surgery for Teen Girls

Title: New Guidelines Issued on Breast, Genital Plastic Surgery for Teen Girls
Category: Health News
Created: 4/22/2016 12:00:00 AM
Last Editorial Review: 4/25/2016 12:00:00 AM




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Trump Says Federal Guidelines on Social Distancing Set to Expire

Title: Trump Says Federal Guidelines on Social Distancing Set to Expire
Category: Health News
Created: 4/30/2020 12:00:00 AM
Last Editorial Review: 4/30/2020 12:00:00 AM




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CDC Draft Guidelines For Reopening U.S. Being Reviewed by White House

Title: CDC Draft Guidelines For Reopening U.S. Being Reviewed by White House
Category: Health News
Created: 5/1/2020 12:00:00 AM
Last Editorial Review: 5/1/2020 12:00:00 AM




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More Airlines to Make Passenger Face Coverings Mandatory

Title: More Airlines to Make Passenger Face Coverings Mandatory
Category: Health News
Created: 5/1/2020 12:00:00 AM
Last Editorial Review: 5/1/2020 12:00:00 AM




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Pregnancy Guidelines During COVID-19 Pandemic

Title: Pregnancy Guidelines During COVID-19 Pandemic
Category: Health News
Created: 4/2/2020 12:00:00 AM
Last Editorial Review: 4/2/2020 12:00:00 AM




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When Booze Labels Carry Health Warnings, Drinking Declines: Study

Title: When Booze Labels Carry Health Warnings, Drinking Declines: Study
Category: Health News
Created: 5/4/2020 12:00:00 AM
Last Editorial Review: 5/4/2020 12:00:00 AM




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Challenges with Adherence to Clinical Practice Guidelines: Lessons for Implementation Science




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Surviving Sepsis Campaign International Guidelines




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Factors Influencing Uptake of Changes to Clinical Preventive Guidelines

Background:

Despite widespread recognition that adherence to clinical preventive guidelines improves patient outcomes, clinicians struggle to implement guideline changes in a timely manner. Multiple factors influence guideline adoption and effective implementation. However, few studies evaluate their collective and inter-related effects. This qualitative study provides a comprehensive picture of the interplay between multiple factors on uptake of new or changed preventive guidelines.

Methods:

Semistructured interviews conducted in 2018 with a diverse sample of clinicians and practice leaders sought to understand patient, clinician, practice, health system, environment, and guideline factors of influence. An immersion-crystallization approach was used to identify emergent themes.

Results:

Interviewees expressed motivation to adhere to guidelines but also valued sharing decisions with patients. Personal biases and fears affected both clinician and patient guideline adoption. Practices facilitated implementation through workflow optimization and encouraging a culture of evidence-based practice while a key health system function was to maintain electronic health record alerts. More traditional environmental factors, such as insurance coverage or transportation, were less of a barrier to guideline adoption and implementation than the influence of media and specialists. Various specific guideline characteristics also affected ease of adoption and implementation. Different settings expressed greater health system, practice, or clinician-centric approaches to guideline implementation.

Conclusions:

Guideline uptake is influenced by a complex interplay of multiple levels of factors including the patient, clinician, practice, health system, environment, and guideline levels. Comprehensively understanding all levels of influence for each specific clinical setting may help to determine the optimal intervention(s) for improving uptake of evidence-based guidelines.




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Correction: Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase. [Additions and Corrections]

VOLUME 295 (2020) PAGES 4079–4092There was an error in the abstract. “The pyridinium cation hampers uptake of OPs into the central nervous system (CNS)” should read as “The pyridinium cation hampers uptake into the central nervous system (CNS).”




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Management of acute COPD exacerbations in Australia: do we follow the guidelines?

Objective

We aimed to assess adherence to the Australian national guideline (COPD-X) against audited practice, and to document the outcomes of patients hospitalised with an acute exacerbation of chronic obstructive pulmonary disease (COPD) at discharge and 28 days after.

Methods

A prospective clinical audit of COPD hospital admission from five tertiary care hospitals in five states of Australia was conducted. Post-discharge follow-up was conducted via telephone to assess for readmission and health status.

Results

There were 207 admissions for acute exacerbation (171 patients; mean 70.2 years old; 50.3% males). Readmission rates at 28 days were 25.4%, with one (0.6%) death during admission and eight (6.1%) post-discharge within 28 days. Concordance to the COPD-X guidance was variable; 22.7% performed spirometry, 81.1% had blood gases collected when forced expiratory volume in 1 s was <1 L, 99.5% had chest radiography performed, 95.1% were prescribed systemic corticosteroids and 95% were prescribed antibiotic therapy. There were 89.1% given oxygen therapy and 92.6% when arterial oxygen tension was <80 mmHg; 65.6% were given ventilatory assistance when pH was <7.35. Only 32.4% were referred to pulmonary rehabilitation but 76.8% had general practitioner follow-up arranged.

Conclusion

When compared against clinical practice guidelines, we found important gaps in management of patients admitted with COPD throughout tertiary care centres in Australia. Strategies to improve guideline uptake are needed to optimise care.




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Advancing Biologics Development Programs with Legacy Cell Lines: Advantages and Limitations of Genetic Testing for Addressing Clonality Concerns Prior to Availability of Late Stage Process and Product Consistency Data

The bioprocessing industry uses recombinant mammalian cell lines to generate therapeutic biologic drugs. To ensure consistent product quality of the therapeutic proteins, it is imperative to have a controlled production process. Regulatory agencies and the biotechnology industry consider cell line "clonal origin" an important aspect of maintaining process control. Demonstration of clonal origin of the cell substrate, or production cell line, has received considerable attention in the past few years, and the industry has improved methods and devised standards to increase the probability and/or assurance of clonal derivation. However, older production cell lines developed before the implementation of these methods, herein referred to as "legacy cell lines," may not meet current regulatory expectations for demonstration of clonal derivation. In this article, the members of the IQ Consortium Working Group on Clonality present our position that the demonstration of process consistency and product comparability of critical quality attributes throughout the development life cycle should be sufficient to approve a license application without additional genetic analysis to support clonal origin, even for legacy cell lines that may not meet current day clonal derivation standards. With this commentary, we discuss advantages and limitations of genetic testing methods to support clonal derivation of legacy cell lines and wish to promote a mutual understanding with the regulatory authorities regarding their optional use during early drug development, subsequent to Investigational New Drug (IND) application and before demonstration of product and process consistency at Biologics License Applications (BLA) submission.




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Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells




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Vampire: The Masquerade - Bloodlines 2 Confirmed for Xbox Series X

It was confirmed at the Inside Xbox event today Vampire: The Masquerade - Bloodlines 2 will be getting a next generation release on the Xbox Series X. It was already confirmed the game will release on the PlayStation 4, Xbox One and Windows PC.

View the latest trailer below:

Here is an overview of the game:

Enter the World of Darkness and rise through vampire society. Experience Seattle - a city full of alluring, dangerous, characters and factions. You are dead now but stronger, quicker, more alluring and with potential for so much more. Choose to be brutal and unflinching or cultured and seductive. Use charm, cunning, terror and sheer will to rise through vampire society. What monster will you be?

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443424/vampire-the-masquerade-bloodlines-2-confirmed-for-xbox-series-x/




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Strange lines on Venus may be folded stacks of lava eroded by wind

Venus’s surface is covered in strange wiggling lines that may form when colossal stacks of lava are carved by gentle winds over hundreds of millions of years




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Chinese airlines eye Qantas

It could be a matter of time before a Chinese airline tries to buy a strategic stake in Qantas.




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Czech Airlines to restart some flights after coronavirus grounding




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White House Misled Public, Buried CDC Reopening Guidelines and is Now Preparing for Second Coronavirus Wave

The White House is making "contingency plans" for a second wave of coronavirus after emails reportedly contradict their claims that Centers for Disease Control and Prevention guidelines to safely reopen the economy were set aside because medical experts did not approve of them.




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When Will Vegas Reopen? Social Distancing Guidelines for Casinos, Drive-Ins, and Restaurants

Restaurants and drive-in movie theatres are allowed to reopen in Las Vegas today, with casinos hoping to reopen by Memorial Day.




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Britain to quarantine travellers for 14 days, UK airlines association says

The British government has told airlines it will introduce a 14-day quarantine period for most people arriving from abroad to try to avoid a second peak of the coronavirus pandemic, an association representing the airlines said on Saturday.




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Dr. Ben Carson: America's economy can reopen 'imminently' by following coronavirus health guidelines, data

America can take its next steps toward reopening by placing an emphasis on emerging health data and closely examining how early states are performing, Housing and Urban Development Secretary Dr. Ben Carson asserted Saturday.



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Student medics graduate early to join NHS frontlines in battle against coronavirus

Read our live coronavirus updates HERE Coronavirus: The symptoms




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US bishop who said &apos;God is larger than this dreaded virus&apos; and ignored social distancing guidelines dies after contracting coronavirus

Coronavirus: the symptoms Read our LIVE updates on the coronavirus here




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New police guidlines state driving to countryside for a walk IS allowed during coronavirus lockdown

Follow our live coronavirus updates HERE Coronavirus: The symptoms




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France outlines plans to ease coronavirus lockdown and reopen schools next month

Secondary school pupils in France will be required to wear masks from next month as they start returning to school under new measures set out by the country's prime minister to ease the coronavirus lockdown.




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Airlines should be able to issue vouchers instead of cash refunds for cancelled flights, EU members say

Airlines should be able to issue vouchers instead of cash refunds for cancelled flights, according to 12 EU member states who have requested a change in the rules to help carriers.




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Government back to work guidelines for businesses: What your workplace could look like after lockdown

Draft proposals for how to return to work safely have been leaked and they paint a very different picture of the workplace post lockdown.​




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Taylor Swift Pens A Thank You Letter To A Nurse Fighting At The Frontlines

Taylor Swift sent a care package to a registered nurse in Utah, Whitney Hilton, who just returned from New York after providing assistance at Northwell Health’s Long Island Jewish Medical Center. “I wanted to send you some presents and to let you know I am so grateful for you”, Swift began in her handwritten note, […]

The post Taylor Swift Pens A Thank You Letter To A Nurse Fighting At The Frontlines appeared first on Chart Attack.





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Mary Gaitskill’s Art of Loneliness

Maggie Doherty

Through her portraits of solitude, Gaitskill forces us to recognize those moments of subtle connection.

The post Mary Gaitskill’s Art of Loneliness appeared first on The Nation.





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Netflix's orc cop thriller sequel 'Bright 2' lines up a director

The sequel to 2017 orc-cop buddy movie Bright, starring Will Smith, has lined up a director.




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Rivers lines up high school job after NFL career

Philip Rivers already has his next job set up, though he won't start coaching the St. Michael Catholic High School football team in Alabama until he retires as an NFL quarterback.




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Trevor Noah calls out Trump for &apos;insane&apos; and &apos;vile&apos; guidelines for ending US lockdown

Presenter deemed president the 'moron-in-chief'




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Brooklyn Nine-Nine to write coronavirus plotlines into show &apos;without it being super tragic&apos;

The new season of the hit cop sitcom will deal with 'how [the characters] have been affected by the virus and the pandemic as first responders in New York City'




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How does coronavirus affect newborns and what guidelines are in place for new parents?

As Carrie Symonds and Boris Johnson welcome a baby boy just one month after the Prime Minister was diagnosed with COVID-19, we examine what to do if you have a new baby in the time of coronavirus




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Gyms &apos;may stay closed until autumn,&apos; as industry body publishes guidelines for fitness studios to open safely

A ban on sweat towels could be introduced under new guidelines from ukactive




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Music Canada applauds Government of Canada for clarifying CERB guidelines for artists and musicians

April 16, 2020, Toronto: Music Canada welcomes the recent clarification from the Federal Government on the guidelines for eligibility for the Canada Emergency Response Benefit (CERB). Prime Minister Justin Trudeau has responded to concerns around the preliminary rules that excluded people working reduced hours. These needed changes will help support artists and musicians who in […]

The post Music Canada applauds Government of Canada for clarifying CERB guidelines for artists and musicians appeared first on Music Canada.




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Dimitar Berbatov on why &apos;impatient&apos; Tottenham boss Jose Mourinho broke coronavirus guidelines

Dimitar Berbatov says Jose Mourinho broke government guidelines to meet with Tanguy Ndombele because the manager is "impatient for football to return".




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Manchester United to remind Marcos Rojo of his responsibilities after video of lockdown guidelines breach

Manchester United will speak to Marcos Rojo after the defender was filmed appearing to flout social distancing guidelines.





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Fear, loneliness, love and kangaroo cuddles what it's like to have a premature baby

The first time I saw my baby Billie was in a photo she'd been born 11 weeks early. The next few months brought agony, loneliness and love and sparked lasting friendships with other mums in the intensive care unit.




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AFP allegedly told ABC lawyer it 'did not want sensationalist headlines' prior to raids

A court hears an Australian Federal Police officer told ABC lawyers he did not want to see "sensationalist headlines" prior to a raid of the broadcaster's Sydney headquarters this year.




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Geoffrey Rush accused of 'delivering lines' during Daily Telegraph defamation appeal

A $2.9 million payout is being challenged in court today after it was found Nationwide News defamed actor Geoffrey Rush in a high-profile case earlier this year.




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Sydney woman Susan Leslie O'Brien sentenced after killing Balinese teenager with car

Sydney woman Susan Leslie O'Brien may be home before Christmas after being sentenced to three-and-a-half months in jail for hitting and killing a Balinese teenager with her car.