During his call with 3,000 members of the Obama Alumni Association, Obama urged his supporters to show their full support towards Democratic presidential candidate Joe Biden.

The UT excise and taxation department has extended the excise policy from May 15 to June 30 due to the Covid-19 pandemic and the ongoing lockdown.

Amid prevalent chaos and uncertainty over access to the essential services and commodities during the lockdown, we bring you the latest updates from your city.

The transmembrane intracellular lectin ER–Golgi intermediate compartment protein 53 (ERGIC-53) and the soluble EF-hand multiple coagulation factor deficiency protein 2 (MCFD2) form a complex that functions as a cargo receptor, trafficking various glycoproteins between the endoplasmic reticulum (ER) and the Golgi apparatus. It has been demonstrated that the carbohydrate-recognition domain (CRD) of ERGIC-53 (ERGIC-53CRD) interacts with N-linked glycans on cargo glycoproteins, whereas MCFD2 recognizes polypeptide segments of cargo glycoproteins. Crystal structures of ERGIC-53CRD complexed with MCFD2 and mannosyl oligosaccharides have revealed protein–protein and protein–sugar binding modes. In contrast, the polypeptide-recognition mechanism of MCFD2 remains largely unknown. Here, a 1.60 Å resolution crystal structure of the ERGIC-53CRD–MCFD2 complex is reported, along with three other crystal forms. Comparison of these structures with those previously reported reveal that MCFD2, but not ERGIC-53–CRD, exhibits significant conformational plasticity that may be relevant to its accommodation of various polypeptide ligands.

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This article reports conformational polymorphisms of the EF-hand protein MCFD2 which is involved in glycoprotein transport..

Timing was critical because female giant pandas ovulate only once a year. A short period of two to three days around ovulation is the only time she is able to conceive. Gestation typically lasts from 90 to 185 days.

The post Smithsonian scientists give giant pandas a helping hand at reproduction appeared first on Smithsonian Insider.

Astronomers using NASA's Chandra X-ray Observatory have found evidence of the youngest black hole known to exist in our cosmic neighborhood. The 30-year-old object is a remnant of SN 1979C, a supernova in the galaxy M100 approximately 50 million light years from Earth.

The post Chandra X-ray Observatory finds youngest nearby black hole appeared first on Smithsonian Insider.

Bats living in the dense urban area of Panama City, the scientists learned, represent just a small fraction of the roughly 25 species of high-flying insectivorous bats found in Panama’s rainforests.

The post Only large, fast-flying bats can handle life in the big city; small bats can’t adapt appeared first on Smithsonian Insider.

Using the deepest X-ray image ever taken, astronomers found the first direct evidence that massive black holes were common in the early universe. This discovery from NASA's Chandra X-ray Observatory shows that very young black holes grew more aggressively than previously thought, in tandem with the growth of their host galaxies.

The post Chandra X-Ray Observatory finds massive black holes common in early universe appeared first on Smithsonian Insider.

Astronomers are confident the Cygnus X-1 system contains a black hole, and with these latest studies they have remarkably precise values of its mass, spin, and distance from Earth.

The post New details on birth of black hole Cygnus X-1 revealed by Chandra X-ray Observatory appeared first on Smithsonian Insider.

The fastest wind ever discovered blowing off a disk around a stellar-mass black hole has been observed by a team of astronomers using NASA’s Chandra X-ray Observatory.

The post Chandra X-ray Observatory clocks stellar wind at 20 million mph appeared first on Smithsonian Insider.

A new study provides a possible explanation for the mysterious flares. The suggestion is that there is a cloud around Sgr A* containing hundreds of trillions of asteroids and comets, which have been stripped from their parent stars.

The post X-ray flares observed by Chandra are asteroids being torn to pieces in a black hole appeared first on Smithsonian Insider.

This composite image from the Chandra X-ray Observatory (operated for NASA by the Smithsonian Astrophysical Observatory) shows the distribution of dark matter, galaxies, and hot […]

The post Chandra image of the core of the merging galaxy cluster Abell 520 appeared first on Smithsonian Insider.

stronomers have used NASA's Chandra X-ray Observatory to find evidence our Milky Way Galaxy is embedded in an enormous halo of hot gas that extends for hundreds of thousands of light years.

The post Chandra X-ray Observatory shows Milky Way is surrounded by halo of hot gas appeared first on Smithsonian Insider.

New data from NASA's Chandra X-ray Observatory suggest a highly distorted supernova remnant (shown here) may contain the most recent black hole formed in the Milky Way galaxy.

The post Highly distorted supernova remnant seen by Chandra X-ray Observatory appeared first on Smithsonian Insider.

Using data from NASA’s Chandra X-ray Observatory, astronomers have discovered an unprecedented bonanza of black holes in the Andromeda Galaxy, one of the nearest galaxies […]

The post Chandra X-ray Observatory turns up black hole bonanza in galaxy next door appeared first on Smithsonian Insider.