AMERICUS, Ga. — Georgia Southwestern State University graduate guard Destiny Garrett was named the Peach Belt Conference Women's Basketball Player of the Week this afternoon by the league office. Garrett set a school record with 13 assists in the 17th-ranked Lady Hurricanes 85-61 win over Florida Tech on Saturday and completed her first-ever double-double with a career-best 21 points. Garrett ...

Kong-Fatt Wong
Jan 25, 2006; 26:1314-1328
BehavioralSystemsCognitive

Thalamocortical pathways from the rodent ventral posterior (VP) thalamic complex to the somatosensory cerebral cortex areas are a key model in modern neuroscience. However, beyond the intensively studied projection from medial VP (VPM) to the primary somatosensory area (S1), the wiring of these pathways remains poorly characterized. We combined micropopulation tract-tracing and single-cell transfection experiments to map the pathways arising from different portions of the VP complex in male mice. We found that pathways originating from different VP regions show differences in area/lamina arborization pattern and axonal varicosity size. Neurons from the rostral VPM subnucleus innervate trigeminal S1 in point-to-point fashion. In contrast, a caudal VPM subnucleus innervates heavily and topographically second somatosensory area (S2), but not S1. Neurons in a third, intermediate VPM subnucleus innervate through branched axons both S1 and S2, with markedly different laminar patterns in each area. A small anterodorsal subnucleus selectively innervates dysgranular S1. The parvicellular VPM subnucleus selectively targets the insular cortex and adjacent portions of S1 and S2. Neurons in the rostral part of the lateral VP nucleus (VPL) innervate spinal S1, while caudal VPL neurons simultaneously target S1 and S2. Rostral and caudal VP nuclei show complementary patterns of calcium-binding protein expression. In addition to the cortex, neurons in caudal VP subnuclei target the sensorimotor striatum. Our finding of a massive projection from VP to S2 separate from the VP projections to S1 adds critical anatomical evidence to the notion that different somatosensory submodalities are processed in parallel in S1 and S2.

GABAergic inhibitory interneurons comprise many subtypes that differ in their molecular, anatomical, and functional properties. In mouse visual cortex, they also differ in their modulation with an animal’s behavioral state, and this state modulation can be predicted from the first principal component (PC) of the gene expression matrix. Here, we ask whether this link between transcriptome and state-dependent processing generalizes across species. To this end, we analysed seven single-cell and single-nucleus RNA sequencing datasets from mouse, human, songbird, and turtle forebrains. Despite homology at the level of cell types, we found clear differences between transcriptomic PCs, with greater dissimilarities between evolutionarily distant species. These dissimilarities arise from two factors: divergence in gene expression within homologous cell types and divergence in cell-type abundance. We also compare the expression of cholinergic receptors, which are thought to causally link transcriptome and state modulation. Several cholinergic receptors predictive of state modulation in mouse interneurons are differentially expressed between species. Circuit modelling and mathematical analyses suggest conditions under which these expression differences could translate into functional differences.

A new exhibition co-presented by the National Portrait Gallery and the Archives of American Art explores the seminal artist’s work

Information Note.

A blockbuster exhibition in Paris is showcasing 500 artifacts and artworks in honor of the Surrealist Manifesto, which sparked a new artistic style that spread around the world

Antonia, a cloned black-footed ferret at the Smithsonian's National Zoo and Conservation Biology Institute, has produced two healthy offspring that will help build genetic diversity in their recovering population

The 1951 artwork, "La Grande Dame (The Cat Woman)," stands over six feet tall and features paintings of "hybrid creatures and lush dreamscapes"

Quebec provincial police have confirmed that the body found in a Montreal nature park on Oct. 30 was that of kidnapping victim and cryptocurrency influencer Kevin Mirshahi.

In a new biopic starring Kate Winslet, Miller's many lives—as an artist, model, muse, cook and war correspondent—need little embellishment

A Fredericton judge suggested a joint sentencing proposal Tuesday was too lenient in the case of a former peace officer who left a loaded gun in the house while his children were home.

The Surrey Police Service is less than three weeks from taking over from the RCMP to manage policing in British Columbia's second most populous municipality, but there's still no formal deal on how responsibilities will be split between the two forces.

A Remembrance Day ceremony in Sarnia, Ont., was disrupted Monday, police say, by the presence and arrest of multiple alleged members of an outlaw motorcycle gang.  

Canadian swingman RJ Barrett was upgraded to day-to-day and engaged in non-contact practise on Monday, two days before Toronto hosts the Cleveland Cavaliers at Scotiabank Arena.

People who experience depression and concussions simultaneously have significantly worse symptoms for both conditions and disruptions to brain connectivity, according to a study by researchers at Penn State.

A boy who knew about the crucifixion but not the resurrection, hears the truth about Jesus and becomes eager to share his discovery with others.

U.S. Supreme Court nominee Amy Coney Barrett said it would be "unthinkable" for the landmark "Brown" desegregation decision to be overruled.

Dig into what two leading Democratic presidential candidates have to say in their platforms about charter schools with Education Week's detailed analysis.

The three Somerville High School juniors allegedly entered a freshman cabin and sexually assaulted three victims.

A three-judge panel from the 9th U.S. Circuit Court of Appeals ruled against a proposed plan that would have paid certain student-athletes as much as $5,000 annually in deferred compensation.

Former Vice President Joe Biden’s recent remarks on his willingness to work with segregationists resurrected his long-ago efforts to oppose school busing. Will it hurt his campaign?

The swirl of attention around Democratic presidential candidate Elizabeth Warren’s story of being forced out of a teaching job when she was pregnant intensifies the spotlight on her background and K-12 credentials.

Dig into what two leading Democratic presidential candidates have to say in their platforms about charter schools with Education Week's detailed analysis.

Michael Pittaro, director of corrections for Northampton County and associate professor of criminal justice at American Military University, shared stories about his experiences over his 35-year career in the field of corrections with Penn State Lehigh Valley criminal justice students recently.

Bitcoin soared to a record high above $81 000 on Monday on expectations that cryptocurrencies will boom in a favourable regulatory environment following the election of Donald Trump as U.S. president and pro-crypto candidates to

Students who play high school sports get better grades, select more challenging courses, and are more likely to enroll in college.

In partnership with the Hope Centre in Durrës, food and supplies were handed out to widows, divorced women and poor families on Women's Day.

Massachusetts Sen. Elizabeth Warren's education plan landed on Monday, and among other consequences, it led to a conversation about her past statements addressing "vouchers."

Virtual reality goggles with a choice of soothing environments or guided meditations, a color-changing bubble wall, a prayer area, Zen garden and massage chair: These are all options provided by Penn State Wilkes-Barre’s Counseling Services to help students relax and stay calm.

Penn State Wilkes-Barre’s Friedman Art Gallery is preparing to open a new exhibit. “Photography of Protest” by photographer Michael Mirabito will open on Oct. 31 and continue until Dec. 3. The gallery is open on weekdays from 8 a.m. to 5 p.m.

Students at Penn State Wilkes-Barre are invited to take part in the annual Mental Health Awareness Day, set for 11:30 a.m. to 1:30 p.m. on Oct. 18. The event is designed to promote mental health awareness and self-care, reduce stigma, and provide students with an opportunity to engage in self-care activities. 

Penn State Wilkes-Barre is hosting an open house for prospective students and their families from 9 a.m. to 1:30 p.m. on Oct. 19.

They first met in kindergarten, and now they’re in college together. Caleb Balas, Nikolas Kistner and Alexis McGrady were educated at Hanover Area schools throughout elementary, middle and high school. Coming from a graduating class of 111 students, they frequently saw each other throughout school. Since they each made their college choice individually, they didn’t know they would continue to see each other at Penn State Wilkes-Barre — and all three said it’s nice seeing familiar faces.

High school students interested in science, technology, engineering, the arts or mathematics (STEAM) are invited to a day of hands-on STEAM activities at Penn State Wilkes-Barre at no cost. “Exploring STEAM Careers” will be held at the campus on Nov. 6. Sessions will be held in the areas of chemistry, engineering, information technology, mathematics and surveying engineering.

Penn State Wilkes-Barre will host a popular community craft show coordinated by Arts at Hayfield on Nov. 3.

Penn State Wilkes-Barre held its first Surveying Career Summit on Oct. 16, providing high school students interested in surveying engineering with the opportunity to visit the campus and learn more about their field of interest.

Penn State Wilkes-Barre was selected as “Best College Campus” in a local media group’s annual readers’ choice awards program.

Penn State Wilkes-Barre has received a donation from the Pennsylvania Land Surveyors’ Foundation, enabling the program to purchase additional equipment.

Penn State Wilkes-Barre will host a ceremony on Veterans Day to honor the bravery and dedication of our nation’s service members on Nov. 11 from 12:15 to 1:15 p.m. The event will also serve as a rededication for the Daniel S. Walko Memorial, which honors a fallen service member who was a campus alumnus.

As time passes for those devastated by fire in a Bangladesh slum, OM helps with essential support and love in variety of ways.

Penn State Wilkes-Barre hosted a workshop in September that allowed students to use their knowledge about a geographic information system to tackle a real-world problem in impoverished communities in Brazil: How can packages be delivered to people who live in areas without official addresses?  

Religious liberty, school choice, teachers' unions, and educational equity all came up at Amy Coney Barrett's high court confirmation hearing. She wasn't always asked to answer.

In a twist worthy of a Bollywood movie, the 24-year-old lyricist of a song in an upcoming Salman Khan film has been arrested for issuing a death threat - purportedly from the Lawrence Bishnoi gang - to the actor and himself.

Lawrence Bishnoi first grabbed headlines when he publicly threatened to kill Bollywood actor Salman Khan in 2018.

Apple unveiled its first mixed-reality headset Vision Pro at WWDC last year. Rumours about its successor have been circulating online for a while, and now Bloomberg's Mark Gurman has suggested the launch timeline for the next generation Apple Vision Pro. Gurman claims that the upcoming model will have a similar design as the current model.

Prosecutors said Bitcoin Fog processed more than $400 million in untraceable transactions, including $78 million involving known darknet markets. Defense lawyer Tor Ekeland called the verdict “disappointing” and said they will appeal.

Telugu comedy-drama Gorre Puranam is now available for streaming on Amazon Prime Video, following its initial release on Aha. The story follows a goat's daring escape from a sacrificial ritual, leading to comedic social chaos and satire. With mixed critical reception and box office results, Gorre Puranam brings an unconventional storyline to audiences, now accessible to Prime subscribers and Aha viewers.

Cross, the new Prime Video crime-thriller series, debuts on November 14, 2024. Featuring Aldis Hodge as Alex Cross, this adaptation goes deeper into the detectives life than previous film versions. With 8 episodes in season 1, the show promises intense action and emotional depth as Cross faces a series of personal and professional challenges. The series marks a reimagined take on James Pattersons iconic character, with all episodes dropping on the same day for binge-watchers.