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Offers get Hosting24 coupons 50% off at offersget.com site. 100% working offersget Hosting24 coupon codes, offers on Shared, Reseller, VPS, Dedicated server hosting.

Hosting24 hosting services? | Hosting24 Hosting company detail at offersget.com site - Basic Web Hosting is one of the least expensive and most regular kind of web hosting services accessible, and furthermore the most ideal approach to begin a website. Shared hosting allude to a web access in which single server is dispensed between numerous sites. Said beneath are the advantages and downsides of this hosting arrangement.




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Broadtail Designs hosts ‘Curvy in Quarantine’ Yoga Live on IG

COVID-19 has completely readjusted how we operate daily. With the proliferation of the ‘work from home’ concept, many persons have become even more stationary as they spend full days on their couches, tapping on their communication devices while...




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Web Hosting coupons, coupon codes. 50% off 100% working Web Hosting discount codes, offers. Offersget promo codes on Shared, Reseller, VPS, Dedicated server hosting.

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SNMMI Hosts FDA Workshop




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AADEJ to host dental editing workshop in Anaheim

Anaheim, Calif. — The American Association of Dental Editors & Journalists is hosting Dental Editors University West May 14-15 at the Anaheim Hilton in Anaheim, California.




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Arizona Dental Association hosts one of the largest virtual dental conferences to date

Scottsdale, Ariz. — In February, the Arizona Dental Association was fully prepared to host the Western Regional Dental Experience April 2-4 at the Renaissance Phoenix Glendale Hotel and Spa.




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Famous birthdays for May 9: Ghostface Killah, Noah Centineo

Rapper Ghostface Killah turns 50 and actor Noah Centineo 24, among the famous birthdays for May 9.




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Ed. Dept. to Host Listening Tour On Texas Special Education Enrollment

Officials want to hear from parents, students and educators in the wake of a newspaper series that said Texas is suppressing special education enrollment.




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Ghost train walk : in the Vales / by Grandmother Christine.

With two quick bursts of the Ghost train's whistle it indicates that the time is 12 midnight, but as quick as we rush out of the front door we have never been able to catch a glimpse of that train, till now! Grammy's tales are being shared through her granddaughter, but are they tales or real events and people, hmm? Read on to find out for yourself. He He. A fictional story set In the Vales as a Children's Bedtime Story. History and characters of this rolling countryside between sea and hills has been packaged up to be fun, informative and thought provoking.




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The Light Horse ghost / Julie Janson.

Aust'n. World War stories 1. From the World War 1 Middle Eastern Theatre of War, the Desert Campaign and the Light Horse military victory, to a quiet family life in a gold mining town. Albert, an Australian Light Horseman tells wild stories of bravery, while Iris his daughter copes with his tumultuous return. We follow a few years in the life of Iris, a teenage girl and her family in Kalgoorlie Boulder in the Gold Fields of Western Australia after 1919. Albert spends his Sunday afternoons drinking beer from a crate in the back yard, with fantastic memories of The Great Ride into Beersheba and Damascus. Iris hears it all and tries to keep her loyalty to her father in the face of his love of a drink, torrid affairs and the departure of her mother, Ailish.




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Ghosts of the tsunami : death and life in Japan's disaster zone / Richard Lloyd Parry.

Tohoku Earthquake and Tsunami, Japan, 2011.




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Lectin in host defense against microbial infections

9789811515804 (electronic bk.)




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NASA and Lego Host ‘Build a Planet’ Challenge

The event was part of the company's week of #LetsBuildTogether challenges




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The Amazon’s 'Ghost Dogs' Face 30 Percent Habitat Loss

The solitary species is hard to spot on camera, and they're the only canine that lives in the Amazon rainforest




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Two-Step Bacterial Artificial Chromosome (BAC) Engineering: Electroporation of Competent BAC Host Cells with the Recombinant Shuttle Vector

Bacterial artificial chromosome (BAC) clones are rendered electrocompetent and transformed with the recombinant shuttle vector, pLD53SCAB/AB-box. Cointegrates are selected by growth on chloramphenicol and ampicillin to ensure recombination of the shuttle vector into the BAC.




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These California Wineries Are Hosting Virtual Wine Tastings

Sheltering in place doesn’t mean you have to give up the best of wine country's offerings




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Bomb scare at Windsor cultural centre turns out to be forgotten ghost-hunting device

It turns out a small black box with a dangling red wire and little blue light investigated by Windsor's bomb squad Tuesday isn't actually dangerous — at least to the living.



  • News/Canada/Windsor

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Canucks and B.C.'s top doctor show interest in hosting NHL games in Vancouver

Provincial health officer Dr. Bonnie Henry says there are ways to safely host NHL games in Vancouver if the league goes ahead with resuming the season in a small number of hub cities.



  • News/Canada/British Columbia

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OM hosts new team in Podgorica

OM’s team in Bar, Montenegro, has been praying to expand the outreach work in the country. Their prayers have finally been answered.




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White House hosts service for National Day of Prayer

Washington D.C., May 7, 2020 / 04:30 pm (CNA).- The White House service for the National Day of Prayer on Thursday focused on protection from the coronavirus pandemic. President Trump said Americans will continue to pray for divine assistance as the nation faces “unforeseen and seemingly unbearable hardships.”

Sister Eneyda Martinez of the Poor Sisters of St. Joseph community in Alexandria, Virginia was one of the religious leaders present to lead attendees in prayer.

“Merciful Savior, heal and comfort the sick so that with health restored, they may give you praise. Divine Physician, accompany our caregivers, so that serving you with patience they may heal wisely. And through wisdom, guide our leaders, so that through seeking remedies they may follow your light,” Sister Eneyda Martinez prayed at the service in the White House’s Rose Garden.

The National Day of Prayer was designated by Congress in 1952, and scheduled in 1988 to be observed annually on the first Thursday in the month of May.

In attendance at the White House service were President Trump and First Lady Melania Trump, as well as Vice President Mike Pence and Second Lady Karen Pence, and Paula White, and other religious leaders from Catholic, Christian, and Mormon churches, and Jewish and Hindu faiths.

The prayer service emphasized prayer for protection from the coronavirus pandemic, as well as prayer for the sick and their families, and health care workers.

“Christ, the Anointed, protect us in body and in spirit, so that free from harm we may be delivered from all affliction,” prayed Sister Eneyda Martinez.

Vice President Pence urged Americans to be “persistent in prayer,” especially for the families of the dead, those sick with the virus, and health care workers, many who have “literally taken the place of loved ones” in being the only close contacts of COVID-19 patients.

On Thursday morning, Trump issued a proclamation, noting the importance of prayer during the pandemic.

“During the past weeks and months, our heads have bowed at places outside of our typical houses of worship, whispering in silent solitude for God to renew our spirit and carry us through unforeseen and seemingly unbearable hardships,” Trump stated.

“Even though we have been unable to gather together in fellowship with our church families, we are still connected through prayer and the calming reassurance that God will lead us through life's many valleys.”

The U.S. Centers for Disease Control was reportedly drafting guidance for states to reopen public accommodations and religious services, but according to the Associated Press on Thursday, the document was buried by the administration.

That document reportedly advised against churches holding services if they were not in a “community no longer requiring significant mitigation.”

However, if that and other certain conditions were in place, churches should take precautions such as ensuring social distancing, wearing of masks by congregants, and intensifying cleaning of churches, the CDC document reportedly said.

State orders have varied in their restrictions on public gatherings during the pandemic; a Kansas stay-at-home order allowed religious gatherings of 10 or fewer people, while Illinois prohibited all religious gatherings.

After every U.S. diocese stopped public Masses during March, Catholic dioceses have started offering public Masses, beginning with the diocese of Las Cruces, New Mexico, with several other dioceses following suit in ensuing days.

Officials from the CDC and the White House spoke with four of the bishops on April 28 and 29 about the resumption of public religious services.




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This ministry is hosting a virtual retreat for infertile people on Mother’s Day

Denver Newsroom, May 8, 2020 / 05:29 pm (CNA).- Mother’s Day is going to look different for most families this year, due to the coronavirus pandemic.

For Catholics, some churches are in the process of slowly re-opening public Masses, but the dispensation from the Sunday obligation continues to stand, as the virus has not gone away and a cure or vaccine has yet to be found.

While most Catholics are eager to return to Mass, a small group of Catholics are relieved that they will not be sitting in a public pew this Mother’s Day.

“We actually heard from one woman who said, ‘I kind of feel badly about saying this, but I'm sort of glad that we won't be in the pews this year for Mother's Day,’” Ann Koshute, founder of Springs in the Desert Catholic ministry, told CNA.


“That's something that we hear and that everybody I think on the team has experienced at one point in this journey,” she said - the desire to avoid Mass on Mother’s Day. That’s because Koshute, along with other members of her ministry, have had painful experiences with infertility, and the customary Mother’s Day blessing given to mothers at many parishes that day can bring their grief and sense of loss poignantly to the fore.


“I think that so often people in our own families, our friends, and even our pastors don't really understand the full extent of the pain and the grief or even the full extent of the issue of infertility, of how many couples are really dealing with it,” she said.


The pain of infertility, and the lack of resources available to Catholics on the subject, was why Koshute and her friend, Kimberly Henkel, founded Springs in the Desert, a Catholic ministry to spiritually and emotionally support women and couples experiencing infertility and infant loss. Originally, Henkel and Koshute, who have both experienced infertility, thought they might write a book. But they decided to start with a ministry website and a blog that could bring people together and allow for other women and couples to share their experiences. The group is relatively new, and held its first retreat in Philadelphia in December. They were set to hold a second one this weekend - Mother’s Day weekend - in the Diocese of Fort Wayne-South Bend, when, well, the pandemic hit.

Now, they’ve moved the retreat online and opened it up to Catholics across the country - and they’ve been overwhelmed by the response.

“We thought that we would be really excited if maybe a couple dozen people found out about it and came. We are over 100 participants now. And it's free and it's going to be available all weekend,” Koshute said. The retreat is trying to address the emotional and spiritual experience of infertility and loss for a broad range of people, Henkel said - from mothers who have miscarried, to women who are past child-bearing years and still grieving the loss of infertility, to women “who feel like their biological clocks are ticking and just haven’t met the right guy.” But now that it's a virtual, pre-recorded, watch-at-your-leisure retreat, it also has the potential to reach a population that is often more reluctant to gather in groups and talk about their experiences of infertility: men. “It's mostly women who are emailing us (about the retreat), although we know that many of their husbands will watch with them. But we've also had a few men email us,” Koshute said.


“One in particular, it just really touched my heart. And he said that he was searching the web for help for his wife on Mother's Day. And I was just so filled with praise and thanksgiving to God for that, for a husband to see that hurt in his wife and to want to find a way to help her,” she added. Men and women typically experience the grief of infertility quite differently, Koshute noted. “For us women, it's so visceral because life is conceived within us and we carry that life. But for a man, it's so different,” she said.

“(Men are) kind of distant from that experience until the child is actually born. And so I think many times men, the grief and the burden that they carry is their wife's. They really carry her sadness and I think feel at a loss because they want to make everything right. They want to fix this, and they want to make her whole. And the mystery of infertility is that it's not that simple. And that's one of the things that makes it so difficult,” she said. Henkel said she experienced her own difficulties in trying to discuss infertility with her husband. Now that they’ve experienced the joy of growing their family through adoption, she said, he is much more open to inviting other men to share their experiences. Henkel said she is hoping that an additional benefit of this retreat being online is that it will facilitate discussions between couples watching the videos together. Both Henkel and Koshute said that while the experience of infertility and loss is painful, and they want to help couples acknowledge and accept that pain, they also want Springs in the Desert to be a positive and supportive experience for couples and women, where they can find hope and redemption even in their suffering. One of the topics they focus on is how all women are called to motherhood in their lives, whether it is spiritual or biological.

“My experience has shown me that my motherhood is really engaged in so many ways that I never considered before,” Koshute said.

“Not just with my godson or with other children in my family, but with women who are older than I who are friends and who might come to me with a difficulty or problem and I can help them,” or by helping family members in need or through charitable works, she added. “That's one of the messages that we try to get across to women and to couples as well, that those kinds of things, what we would maybe refer to as spiritual motherhood, is not illegitimate,” she said.

“It's not second-place. It's a real way of engaging and living out our motherhood. It's also not a replacement for a baby. So it's not as if you go out and volunteer in your community and now you won't have this longing for a child anymore. But we've really found through our own experience and through talking with other women that the more we kind of put ourselves out there and give ourselves to others, the more that we can begin to see that motherhood enacted in us.”

Henkel said she also likes to encourage couples to look at the ways God is calling them to be fruitful in their marriages outside of biological children.

“We really encourage these couples that they are not forgotten, they're not being punished. That God loves them so much and that he has something amazing for them. He's using this to draw them near to him and to allow them to cry out to him and ask for him to guide them, to lead them, to give them his love and show them what fruitfulness he has for them, what place in ministry and mission he has for them.” Henkel and her husband in particular like to share with couples their experience of foster care as one example of where God might be calling them to be fruitful. After a frustrating and expensive experience with some adoption agencies, Henkel and her husband decided to look into giving a home to children through foster care.

“Here is a situation where these children really need families,” she said. “It's hard because there's no guarantee you're going to get to keep this child, so there's a sense of this new greater level of having to learn how to trust God.” “I think that with a couple discerning that fruitfulness, it's also discerning - where is God really calling you? There's so much need in this world. And he wants to use us.”

Couples interested in the Springs in the Desert Mother’s Day weekend retreat can sign up for free online at the Springs in the Desert website. Content will be uploaded and available for anyone who registers, Henkel said, even if they register late. The retreat team will also be hosting a live talk on Sunday, May 10 at 2 p.m. Eastern on the ministry’s Facebook page.

“There's a place for you in Springs of the Desert,” Henkel added. “There's so many women who have reached out to us in Philly. We added several more women to our group, to our team, our official team, women who came to the retreat. One woman had come there and she said she had had a miscarriage, and neither one of us has experienced that. So we said, please join us. We want your voice.”

“We're trying to really bring the voices of many different women to our team so that people will feel there is somebody that is talking they can really relate to. Because there are all of these different situations, but they've got obviously a very similar undercurrent.”




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Dealing with Savimbi's Ghost: The Security and Humanitarian Challenges in Angola




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This ministry is hosting a virtual retreat for infertile people on Mother’s Day

Denver Newsroom, May 8, 2020 / 05:29 pm (CNA).- Mother’s Day is going to look different for most families this year, due to the coronavirus pandemic.

For Catholics, some churches are in the process of slowly re-opening public Masses, but the dispensation from the Sunday obligation continues to stand, as the virus has not gone away and a cure or vaccine has yet to be found.

While most Catholics are eager to return to Mass, a small group of Catholics are relieved that they will not be sitting in a public pew this Mother’s Day.

“We actually heard from one woman who said, ‘I kind of feel badly about saying this, but I'm sort of glad that we won't be in the pews this year for Mother's Day,’” Ann Koshute, founder of Springs in the Desert Catholic ministry, told CNA.


“That's something that we hear and that everybody I think on the team has experienced at one point in this journey,” she said - the desire to avoid Mass on Mother’s Day. That’s because Koshute, along with other members of her ministry, have had painful experiences with infertility, and the customary Mother’s Day blessing given to mothers at many parishes that day can bring their grief and sense of loss poignantly to the fore.


“I think that so often people in our own families, our friends, and even our pastors don't really understand the full extent of the pain and the grief or even the full extent of the issue of infertility, of how many couples are really dealing with it,” she said.


The pain of infertility, and the lack of resources available to Catholics on the subject, was why Koshute and her friend, Kimberly Henkel, founded Springs in the Desert, a Catholic ministry to spiritually and emotionally support women and couples experiencing infertility and infant loss. Originally, Henkel and Koshute, who have both experienced infertility, thought they might write a book. But they decided to start with a ministry website and a blog that could bring people together and allow for other women and couples to share their experiences. The group is relatively new, and held its first retreat in Philadelphia in December. They were set to hold a second one this weekend - Mother’s Day weekend - in the Diocese of Fort Wayne-South Bend, when, well, the pandemic hit.

Now, they’ve moved the retreat online and opened it up to Catholics across the country - and they’ve been overwhelmed by the response.

“We thought that we would be really excited if maybe a couple dozen people found out about it and came. We are over 100 participants now. And it's free and it's going to be available all weekend,” Koshute said. The retreat is trying to address the emotional and spiritual experience of infertility and loss for a broad range of people, Henkel said - from mothers who have miscarried, to women who are past child-bearing years and still grieving the loss of infertility, to women “who feel like their biological clocks are ticking and just haven’t met the right guy.” But now that it's a virtual, pre-recorded, watch-at-your-leisure retreat, it also has the potential to reach a population that is often more reluctant to gather in groups and talk about their experiences of infertility: men. “It's mostly women who are emailing us (about the retreat), although we know that many of their husbands will watch with them. But we've also had a few men email us,” Koshute said.


“One in particular, it just really touched my heart. And he said that he was searching the web for help for his wife on Mother's Day. And I was just so filled with praise and thanksgiving to God for that, for a husband to see that hurt in his wife and to want to find a way to help her,” she added. Men and women typically experience the grief of infertility quite differently, Koshute noted. “For us women, it's so visceral because life is conceived within us and we carry that life. But for a man, it's so different,” she said.

“(Men are) kind of distant from that experience until the child is actually born. And so I think many times men, the grief and the burden that they carry is their wife's. They really carry her sadness and I think feel at a loss because they want to make everything right. They want to fix this, and they want to make her whole. And the mystery of infertility is that it's not that simple. And that's one of the things that makes it so difficult,” she said. Henkel said she experienced her own difficulties in trying to discuss infertility with her husband. Now that they’ve experienced the joy of growing their family through adoption, she said, he is much more open to inviting other men to share their experiences. Henkel said she is hoping that an additional benefit of this retreat being online is that it will facilitate discussions between couples watching the videos together. Both Henkel and Koshute said that while the experience of infertility and loss is painful, and they want to help couples acknowledge and accept that pain, they also want Springs in the Desert to be a positive and supportive experience for couples and women, where they can find hope and redemption even in their suffering. One of the topics they focus on is how all women are called to motherhood in their lives, whether it is spiritual or biological.

“My experience has shown me that my motherhood is really engaged in so many ways that I never considered before,” Koshute said.

“Not just with my godson or with other children in my family, but with women who are older than I who are friends and who might come to me with a difficulty or problem and I can help them,” or by helping family members in need or through charitable works, she added. “That's one of the messages that we try to get across to women and to couples as well, that those kinds of things, what we would maybe refer to as spiritual motherhood, is not illegitimate,” she said.

“It's not second-place. It's a real way of engaging and living out our motherhood. It's also not a replacement for a baby. So it's not as if you go out and volunteer in your community and now you won't have this longing for a child anymore. But we've really found through our own experience and through talking with other women that the more we kind of put ourselves out there and give ourselves to others, the more that we can begin to see that motherhood enacted in us.”

Henkel said she also likes to encourage couples to look at the ways God is calling them to be fruitful in their marriages outside of biological children.

“We really encourage these couples that they are not forgotten, they're not being punished. That God loves them so much and that he has something amazing for them. He's using this to draw them near to him and to allow them to cry out to him and ask for him to guide them, to lead them, to give them his love and show them what fruitfulness he has for them, what place in ministry and mission he has for them.” Henkel and her husband in particular like to share with couples their experience of foster care as one example of where God might be calling them to be fruitful. After a frustrating and expensive experience with some adoption agencies, Henkel and her husband decided to look into giving a home to children through foster care.

“Here is a situation where these children really need families,” she said. “It's hard because there's no guarantee you're going to get to keep this child, so there's a sense of this new greater level of having to learn how to trust God.” “I think that with a couple discerning that fruitfulness, it's also discerning - where is God really calling you? There's so much need in this world. And he wants to use us.”

Couples interested in the Springs in the Desert Mother’s Day weekend retreat can sign up for free online at the Springs in the Desert website. Content will be uploaded and available for anyone who registers, Henkel said, even if they register late. The retreat team will also be hosting a live talk on Sunday, May 10 at 2 p.m. Eastern on the ministry’s Facebook page.

“There's a place for you in Springs of the Desert,” Henkel added. “There's so many women who have reached out to us in Philly. We added several more women to our group, to our team, our official team, women who came to the retreat. One woman had come there and she said she had had a miscarriage, and neither one of us has experienced that. So we said, please join us. We want your voice.”

“We're trying to really bring the voices of many different women to our team so that people will feel there is somebody that is talking they can really relate to. Because there are all of these different situations, but they've got obviously a very similar undercurrent.”




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Leonard Cheshire Disability host Fashion Show in Glasgow

Words: Abbie Lyall




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Glasgow to host Homebuyer Show Scotland

Next month will bring the launch of the Homebuyer Show Scotland, an exciting new event for homebuyers looking to make their next move – and the event is set to make its debut in Glasgow. From frustrated first time buyers to struggling second steppers, and families looking for room to grow, Homebuyer Show Scotland is the first of its kind in Scotland and is designed to help any buyer find their next home, arming them with all information they need to make their next move.




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Norway to host UEFA Grassroots Workshop

The next UEFA Grassroots Workshop in 2013 will be hosted by the Football Association of Norway, an organisation renowned for its achievements in this vital area of the game.




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SRU 'very happy' to to host Scottish Cup semi-final between Hearts and Hibs

THE SRU would be “very happy” to host the Scottish Cup semi-final between Heart of Midlothian and Hibernian at BT Murrayfield, the governing body’s Chief Operating Officer revealed yesterday.




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Bavaria to host Regions' Cup in June

Bavaria will host the eight-team UEFA Regions' Cup finals from 18 to 26 June.




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Postural Orthostatic Tachycardia Syndrome (POTS) and Vitamin B12 Deficiency in Adolescents

Studies have shown dysfunction in the baroreflex mechanism and the autonomic nervous system, particularly in the sympathetic nervous system, in the pathophysiology of chronic fatigue syndrome, postural orthostatic tachycardia syndrome, and syncope.

Vitamin B12 deficiency is associated with postural orthostatic tachycardia syndrome in adolescence. (Read the full article)




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Fin24.com | Beirut's ghost apartments are haunting the economy

Permanently-drawn curtains on the city’s empty luxury high-rises and dust gathering over shuttered storefronts in the Beirut Souks mall offer a glimpse of the economic gloom gathering over one of the world’s most indebted countries.




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Novel peptide from commensal Staphylococcus simulans blocks MRSA quorum sensing and protects host skin from damage [Mechanisms of Action]

Recent studies highlight the abundance of commensal coagulase-negative staphylococci (CoNS) on healthy skin. Evidence suggests that CoNS actively shape the skin immunological and microbial milieu to resist colonization or infection by opportunistic pathogens, including methicillin resistant Staphylococcus aureus (MRSA), in a variety of mechanisms collectively termed colonization resistance. One potential colonization resistance mechanism is the application of quorum sensing, also called the Accessory Gene Regulator (agr) system, which is ubiquitous among staphylococci. Common and rare CoNS make autoinducing peptides (AIPs) that function as MRSA agr inhibitors, protecting the host from invasive infection. In a screen of CoNS spent media we found that Staphylococcus simulans, a rare human skin colonizer and frequent livestock colonizer, released potent inhibitors of all classes of MRSA agr signaling. We identified three S. simulans agr classes, and have shown intraspecies cross-talk between non-cognate S. simulans agr types for the first time. The S. simulans AIP-I structure was confirmed, and the novel AIP-II and AIP-III structures were solved via mass spectrometry. Synthetic S. simulans AIPs inhibited MRSA agr signaling with nanomolar potency. S. simulans in competition with MRSA reduced dermonecrotic and epicutaneous skin injury in murine models. Addition of synthetic AIP-I also effectively reduced MRSA dermonecrosis and epicutaneous skin injury in murine models. These results demonstrate potent anti-MRSA quorum sensing inhibition by a rare human skin commensal, and suggest that cross-talk between CoNS and MRSA may be important in maintaining healthy skin homeostasis and preventing MRSA skin damage during colonization or acute infection.




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In vitro and in vivo antibiotic capacity of two host defence peptides [Mechanisms of Action]

Two non-amidated host defence peptides named Pin2[G] and FA1 were evaluated against three types of pathogenic bacteria; two isolated from diabetic foot ulcer patients, Staphylococcus aureus UPD13 and Pseudomonas aeruginosa UPD3, and another from a commercial collection, Salmonella enterica serovar Typhimurium (ATCC 14028). In vitro experiments showed that the antimicrobial performance of the synthetic peptides, Pin2[G] and FA1, was modest, although FA1 was more effective than Pin2[G]. In contrast Pin2[G] had superior in vivo anti-infective activity to FA1 in rabbit wound infections by the diabetic foot ulcer pathogens S. aureus UPD13 and P. aeruginosa UPD3. Indeed, Pin2[G] reduced bacterial colony counts of both S. aureus UPD13 and P. aeruginosa UPD3 by >100,000-fold after 48-72 h on skin wounds of infected rabbits, while in similar infected wounds, FA1 had no major effects at 72-96 h of treatment. Ceftriaxone was equally effective vs. Pseudomonas but less effective vs. S. aureus infections. Additionally, the two peptides were evaluated in mice against intragastrically inoculated S. enterica ser. Typhimurium (ATCC 14028). Only Pin2[G], at 0.56 mg/kg, was effective in reducing systemic (liver) infection by >67-fold, equivalent to the effect of treatment with levofloxacin. Pin2[G] showed superior immunomodulatory activity in increasing chemokine production by a human bronchial cell line and suppressing poly(IC)-induced pro-inflammatory IL6 production. These data showed that the in vitro antimicrobial activity of these peptides was not correlated with their in vivo anti-infective activity, and suggest that other factors such as immunomodulatory activity were more important.




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Influence of CYP2C8, CYP3A4 and CYP3A5 host genotypes on early recurrence of Plasmodium vivax [Mechanisms of Resistance]

CYP450 enzymes are involved in biotransformation of chloroquine (CQ), but the role of the different metabolism profiles of this drug has not been properly investigated in relation to P. vivax recurrences. To investigate the influence of CYPs genotypes associated with CQ-metabolism on early recurrence rates of P. vivax, a case-control study was carried out. Cases included patients presenting an early recurrence (CQ-recurrent), defined as recurrence during the first 28 days after initial infection, plasma concentrations of CQ plus desethylchloroquine (DCQ, the major CQ metabolite) higher than 100 ng/mL. A control (CQ-responsive) with no parasite recurrence over the follow-up was also included. CQ and DCQ plasma levels were measured on Day 28. CQ CYPs (CYP2C8, CYP3A4 and CYP3A5) genotypes were determined by real-time PCR. An ex vivo study was conducted to verify CQ and DCQ efficacy in P. vivax isolates. The frequency of alleles associated with normal and slow metabolism was similar between the cases and controls for CYP2C8 (OR=1.45, 95% CI=0.51-4.14, p=0.570), CYP3A4 (OR=2.38, 95% CI=0.92-6.19, p=0.105) and CYP3A5 (OR=4.17, 95% CI=0.79-22.04, p=1.038) genes. DCQ levels were higher than CQ, regardless of the genotype. Regarding the DCQ/CQ rate, there was no difference between groups or between those patients who had a normal or mutant genotype. DCQ and CQ showed similar efficacy ex vivo. CYPs genotypes had no influence on early recurrence rates. Similar efficacy of CQ and DCQ ex vivo could explain the absence of therapeutic failure, despite presence of alleles associated with slow metabolism.




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Web Hosting Hub

Web Hosting Hub offers excellent customer support and strong shared and WordPress hosting, but it lacks the advanced hosting options that many growing businesses will eventually need.




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HostGator Web Hosting

HostGator is an excellent web hosting service that's simple to use and offers an array of useful plans for consumers and small businesses. It's our top pick for shared web hosting and for novice webmasters in general.




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Lehigh Valley hosts virtual Transfer Thursday events

Prospective transfer students can explore the Lehigh Valley Campus virtually during the Transfer Thursday events




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Campus Recreation to host Virtual 5K

Campus Recreation, a unit of Penn State Student Affairs, is hosting the first ever “We Are Penn State Virtual 5K,” with the opportunity to benefit the Penn State Student Care and Advocacy Student Emergency Fund.




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England to host UEFA Women's EURO 2021

England has been selected to host the 16-team UEFA Women's EURO 2021.




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Women’s EURO 2021 host cities’ workshop

The inaugural Women’s EURO 2021 host cities’ workshop has taken place in host country England – with the aim being to deliver a record-breaking tournament that leaves a legacy for girls’ and women’s football.




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The Best Cheap Web Hosting Services for 2020

Web hosting doesn't need to be expensive. In fact, it can be extremely low cost. If you want solid hosting that won't drain your bank account, these are the 10 best cheap web hosting services that we've reviewed.




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Penn State Law to host panel discussion on current Supreme Court term

Penn State Law in University Park will host "A Take on the Term" with Sarah Harrington and Erin Murphy, beginning at 4:30 p.m. Thursday, March 5, in the Sutliff Auditorium of the Lewis Katz Building.




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Cloudways Web Hosting

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Ghosts and life after death

By Bishop Arthur Serratelli

One of the most famous figures of all English literature is the ghost of Hamlet’s father. Three times he appears in Shakespeare’s play The Tragedy of Hamlet, Prince of Denmark. He demands that his son settle accounts with his uncle who murdered the dead king. In Shakespeare’s Macbeth, Julius Caesar and Richard III, ghosts also appear. From the 3rd century B.C. Epic of Gilgamesh through Homer, Virgil, Ovid, Shakespeare and Dickens, ghosts populated the pages of literature. They have appeared in films and even starred in their own TV show, Ghost Hunters.

Are ghosts merely fictional? Do they really exist?  First Lady Grace Coolidge said that she saw Abraham Lincoln’s ghost looking out the window of the Oval Office. Many others have, likewise, reported sightings of the ghost of our 16th President at the White House. Among those claiming to have seen a spectral Lincoln are Theodore Roosevelt, Winston Churchill, Queen Wilhelmina of the Netherlands and President Reagan’s daughter Maureen.

Within the Old Testament, there is the famous incident of the ghost of the prophet Samuel. In 1 Samuel 28, King Saul is facing a fierce battle with the Philistines. He wants to know the outcome; and, so he consults the witch of Endor. The spirit of the dead prophet Samuel appears and predicts Saul’s imminent defeat and death. Some commentators say that Samuel came because God allowed him to come and speak on God’s behalf (cf. Sir 46:20). Other commentators consider this incident a demonic apparition. In either case, they accept the apparition.

The New Testament gives evidence that the disciples of Jesus believed in the reality of ghosts. After the miracle of the loaves and fish, “when the disciples saw Jesus walking on the sea, they were terrified. ‘It is a ghost,’ they said, and they cried out in fear” (Mt 14:26). When the Risen Lord appeared to the disciples in the Upper Room in Jerusalem on Easter Sunday, “they were startled and terrified and thought that they were seeing a ghost. Then [Jesus] said to them, ‘Why are you troubled? And why do questions arise in your hearts? Look at my hands and my feet, that it is I myself. Touch me and see, because a ghost does not have flesh and bones as you can see I have’ ” (Lk 24:37-39). 

The word “ghost” simply means “spirit.” It refers to the spirit of a deceased person who has made himself or herself present to the living. According to polls taken in the last ten years, almost forty-two percent of Americans believe in ghosts. According to a recent poll, almost thirty percent of Americans say they have been in touch with someone who has died.

Stories about contact with the dead continue to fascinate us. They provoke the imagination. They manifest our awareness that there is more to reality than the physical world which we empirically experience. These reports of the spirits of those who have died clearly suggest personal survival after death. 

In her wisdom, the Church rightly condemns consulting mediums to be in touch with the dead. In fact, “all forms of divination are to be rejected: recourse to Satan or demons, conjuring up the dead or other practices falsely supposed to ‘unveil’ the future. Consulting horoscopes, astrology, palm reading, interpretation of omens and lots, the phenomena of clairvoyance, and recourse to mediums all conceal a desire for power over time, history, and, in the last analysis, other human beings, as well as a wish to conciliate hidden powers. They contradict the honor, respect, and loving fear that we owe to God alone” (Catechism of the Catholic Church, 2116).

As Catholics, we hold that, at death, we face an immediate judgment of our lives. If we are in the state of perfect charity, we go to heaven. If we die in the state of mortal sin (God forbid!), we suffer eternal estrangement from God in hell. And, those of us who die in the state of grace, but not in perfect charity, undergo a purification of love in purgatory before we come into the presence of God. In a word, death is not the end of our personal existence. Nor does the Grim Reaper sever our relationships with each other. All tales of ominous specters appearing from beyond the grave pale before the brilliant truth of the Risen Christ who leaves the tomb empty and joins the living and the dead in one holy Communion of Saints where we assist each other with our prayers!
 



  • CNA Columns: From the Bishops

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