mid Discovery and optimisation of pyrazolo[1,5-a]pyrimidines as aryl hydrocarbon receptor antagonists By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3477-3484DOI: 10.1039/D4MD00266K, Research ArticleRaitis Bobrovs, Svetlana Terentjeva, Ninni Elise Olafsen, Zilvinas Dambrauskas, Antanas Gulbinas, Toivo Maimets, Indrek Teino, Aigars Jirgensons, Jason Matthews, Kristaps JaudzemsThe aryl hydrocarbon receptor (AHR) is a versatile ligand-dependent transcription factor involved in diverse biological processes, from metabolic adaptations to immune system regulation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00594E, Research ArticleNagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza ElrayessOne benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Amides of moronic acid and morolic acid with the tripeptides MAG and GAM targeting antimicrobial, antiviral and cytotoxic effects By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00742E, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Uladzimir Bildziukevich, Lucie Cerna, Jana Trylčová, Marie Kvasnicova, Lucie Rárová, David Šaman, Petra Lovecká, Jan Weber, Zdenek WimmerA series of amides of the selected plant triterpenoids, moronic acid and morolic acid, with the tripeptides MAG and GAM was designed and synthesized. Two required tripeptides 5 and 10...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Novel benzenesulfonamides containing a dual triazole moiety with selective carbonic anhydrase inhibition and anticancer activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00617H, Research ArticleAida Buza, Cüneyt Türkeş, Mustafa Arslan, Yeliz Demir, Busra Dincer, Arleta Rifati Nixha, Şükrü BeydemirIn this research, a series of sulfonamides incorporating a 1,2,3-triazolyloxime substituted 1,2,3-triazolyl moiety was conceptualized, synthesized, and investigated as carbonic anhydrase inhibitors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00619D, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marina Perieteanu, Tayner Rodriguez Garzon, Leah M. C. McGee, Abedawn I. Khalaf, Colin J. Suckling, Rebecca Beveridge, Vicky M. Avery, Fraser J. Scott25 S-MGBs, including those bearing an amidine tail group, were investigated for their antiplasmodial, in vitro activity against 3D7 and Dd2 strains of P. falciparum. Several potent, and selective, hit compounds were identified.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Banking on the middle ground By www.thehindubusinessline.com Published On :: Sun, 17 Jan 2021 20:34:09 +0530 The book is long on analysis but short on solutions Full Article Opinion
mid Sensex, Nifty close higher amid buying in heavyweight stocks, firm global cues By www.thehindu.com Published On :: Thu, 10 Oct 2024 16:48:24 +0530 The sensex rose 144.31 points to settle at 81,611.41 and Nifty increased 16.50 points to close at 24,998.45 Full Article Markets
mid Markets fall in early trade amid foreign fund outflows By www.thehindu.com Published On :: Wed, 16 Oct 2024 10:38:52 +0530 The BSE Sensex went down by 240.75 points to 81,579.37 in early trade. The NSE Nifty declined 62.7 points to 24,994.65 Full Article Markets
mid Stock markets close lower for 2nd day amid foreign fund outflows By www.thehindu.com Published On :: Wed, 16 Oct 2024 16:32:53 +0530 HDFC Bank, Bharti Airtel, Reliance Industries, Asian Paints and State Bank of India were the gainers Full Article Markets
mid Markets fall after rising in opening trade amid unabated foreign fund outflows By www.thehindu.com Published On :: Thu, 17 Oct 2024 10:21:20 +0530 From the 30 Sensex firms, Infosys, State Bank of India, Larsen & Toubro, Reliance Industries, Sun Pharma and Tata Consultancy Services were the biggest gainers Full Article Business
mid Sensex, Nifty fall for 3rd day amid foreign fund exodus By www.thehindu.com Published On :: Thu, 17 Oct 2024 16:35:49 +0530 Intense selling in realty, auto, consumer discretionary and consumer durable stocks also dragged the markets lower Full Article Markets
mid Markets rebound in early trade amid buying in blue-chip stocks By www.thehindu.com Published On :: Tue, 22 Oct 2024 10:36:48 +0530 Equity market indices rebound with blue-chip stocks, fund inflows; Sensex climbs 239.33 points, Nifty up by 72.95 points Full Article Markets
mid IndusInd Bank shares plunge 17%; Mcap erodes by ₹15,572 crore amid disappointing earnings By www.thehindu.com Published On :: Fri, 25 Oct 2024 11:51:35 +0530 Total income rose to ₹14,871 crore in the quarter under review, from ₹13,530 crore in the same period a year ago, IndusInd Bank said in a regulatory filing Full Article Markets
mid Sensex, Nifty tank nearly 1% amid sharp fall in IndusInd Bank, foreign fund outflows By www.thehindu.com Published On :: Fri, 25 Oct 2024 16:43:14 +0530 The BSE Sensex plummeted 662.87 points or 0.83% to settle at 79,402.29. The NSE Nifty tanked 218.60 points or 0.90% to 24,180.80 Full Article Markets
mid Markets fall in early trade amid unabated foreign fund outflows By www.thehindu.com Published On :: Tue, 05 Nov 2024 10:15:59 +0530 The BSE Sensex declined 326.58 points to 78,455.66 in early trade Full Article Markets
mid Microrheology of gemini surfactants at interfaces and in solutions in the dilute and semidilute regimes By pubs.rsc.org Published On :: Soft Matter, 2024, Advance ArticleDOI: 10.1039/D4SM00860J, PaperMayssa Medfai, Antonio Stocco, Christophe Blanc, Maurizio Nobili, Martin InThe interface of semidilute Gemini surfactant solutions remains fluid and is less viscous than the bulk. Depletion of the viscosity near the interface plays a key role in microrheology.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Entropically and enthalpically driven self-assembly of a naphthalimide-based luminescent organic π-amphiphile in water By pubs.rsc.org Published On :: Soft Matter, 2024, 20,8684-8691DOI: 10.1039/D4SM00986J, PaperSk Mursed Ali, Sujauddin Sk, Shuvajyoti Sarkar, Sayani Das, Nayim Sepay, Mijanur Rahaman MollaEntropically and enthalpically favourable vesicular self-assembly of a naphthalimide based water soluble luminescent organic dipolar building block is reported.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Bitcoin hits record high, soars above $75000 amid US election results By www.thehindubusinessline.com Published On :: Wed, 06 Nov 2024 15:12:06 +0530 Industry experts attribute surge to substantial inflows into exchange-traded funds (ETFs), increased speculation surrounding the election outcomes Full Article Crypto Currency
mid Srisailam temple witnesses high devotee influx amid Karthika Masam By www.thehindu.com Published On :: Sun, 10 Nov 2024 19:27:54 +0530 Devotees are allowed darshan from 4.30 a.m. to 4 p.m. and from 5.30 p.m. to 11 p.m. Full Article Andhra Pradesh
mid A.P. govt. presented a pro-people budget amid precarious financial conditions, says I&PR Minister By www.thehindu.com Published On :: Mon, 11 Nov 2024 18:18:36 +0530 Govt.’s approach is a response to the financial mess inherited from the previous YSRCP govt., says I&PR Minister Full Article Andhra Pradesh
mid Processes, terms and cycles [electronic resource] : steps on the road to infinity : essays dedicated to Jan Willem Klop on the occasion of his 60th birthday / Aart Middeldorp [and others] (eds.) By darius.uleth.ca Published On :: Berlin ; New York : Springer, [2005] Full Article
mid Sensex, Nifty fall in early trade amid foreign fund exodus By www.thehindu.com Published On :: Fri, 08 Nov 2024 10:43:13 +0530 The stock market indices fall due to foreign fund outflows and weak blue-chip stocks; RBI to unveil monetary policy next month Full Article Markets
mid Sensex, Nifty fall for 2nd day amid foreign fund exodus, muted corporate earnings By www.thehindu.com Published On :: Fri, 08 Nov 2024 16:13:32 +0530 In Asian markets, Seoul, Shanghai and Hong Kong settled lower while Tokyo ended in the positive territory. European markets were trading lower. Wall Street ended mostly higher Full Article Markets
mid Markets decline in early trade amid unabated foreign fund outflows, muted earnings By www.thehindu.com Published On :: Mon, 11 Nov 2024 11:46:41 +0530 Sensex and Nifty fall due to foreign fund outflows, disappointing earnings, and weak Asian markets, impacting investor sentiment Full Article Markets
mid Sensex, Nifty close flat amid unabated foreign fund outflows, muted earnings By www.thehindu.com Published On :: Mon, 11 Nov 2024 16:33:01 +0530 The stock indices close flat amid Foreign Institutional Investors selling, weak earnings, and volatile trade; Asian markets trend lower Full Article Markets
mid India’s retail equity investment cult rises to a new high amid record FPI outflows By www.thehindu.com Published On :: Mon, 11 Nov 2024 21:50:04 +0530 Full Article Business
mid Market investors become poorer by ₹5.29 lakh crore amid massive correction in stocks By www.thehindu.com Published On :: Tue, 12 Nov 2024 17:41:45 +0530 The BSE benchmark gauge tumbled 820.97 points or 1.03% to settle at 78,675.18 Full Article Markets
mid Bengaluru residential real estate soars amid high demand and limited inventory By www.thehindubusinessline.com Published On :: Mon, 09 Sep 2024 09:03:06 +0530 Areas such as Bagaluru, Hennur, Whitefield, and Varthur-Sarjapur are witnessing substantial price increases, attributed to pent-up demand from the pandemic Full Article Real Estate
mid An efficient approach to AviCys analogues via regio- and stereoselective hydrosulfuration of ynamides By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01572J, Research ArticleZhenjia Zhang, Zhe Ding, Jinhua Yang, Yongli Zhao, Zhenguang Zhao, Can Liu, Norman Metanis, Junfeng ZhaoA novel synthetic strategy for the construction of AviCys analogues via a highly efficient regio- and stereoselective hydrosulfuration of ynamides was reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Facile one-pot synthesis of novel imidates as multifunctional organic fluorescent materials By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01628A, Research ArticleFeng-Ting Liu, Shuo Wang, Yong-Shun Chen, Jun-Ying Miao, Bao-Xiang Zhao, Zhao-Min LinA novel one-pot synthesis of multifunctional organic fluorescent imidates from quinolinium salt derivatives, nitrosoarenes and alcohols was presented. This method had a wide substrate scope and excellent isolated yields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Sulfenylation of bioactive maleimides, acrylates and cyclohexenones under ambient organophotocatalysis By pubs.rsc.org Published On :: Org. Chem. Front., 2024, 11,6503-6509DOI: 10.1039/D4QO01342E, Research ArticleDebanjana Bag, Rajjakfur Rahaman, Anindya S. Manna, Subhasis Pal, Rajesh Nandi, Shobhon Aich, Narendra Nath Ghosh, Dilip K. MaitiA novel visible light-induced sulfenylation of biologically important maleimides, acrylates and cyclohexenones has been developed using cheap and easily available organophotoredox catalyst Eosin Y with thiols under ambient conditions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Regio- and stereoselective azidation of activated N-allenamides: an entry to α, β, γ and δ-amido-azides By pubs.rsc.org Published On :: Org. Chem. Front., 2024, Advance ArticleDOI: 10.1039/D4QO01802H, Research ArticleDorian Schutz, Maxime Hourtoule, Laurence MieschA totally controlled regiodivergent azidation of activated N-allenamides is described, offering a broad range of diverse functionalized amido-azide derivatives.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Convergent Synthetic Approaches to Polycyclic Aromatic Dicarboximides By pubs.rsc.org Published On :: Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D4QO01828A, Review ArticleKazutaka Shoyama, Frank WuerthnerPolycyclic aromatic dicarboximides (PADIs) as represented by naphthalene and perylene bis(dicarboximide) are useful molecules for a variety of functional materials and remain important synthetic targets for organic chemists. In this...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Intermolecular Defluorinative 1,2-Diamination of Fluoroalkenyl Iodides with Sulfonamides: Synthesis of Acyclic and Cyclic Fluorinated 1,2-Enediamines By pubs.rsc.org Published On :: Org. Chem. Front., 2025, Accepted ManuscriptDOI: 10.1039/D4QO01913J, Research ArticleXue-Qiang Chu, Yu-Lan Chen, Chi Zhang, Xue-Ying Huang, Yu Ding, Danhua Ge, Zhi-Liang ShenAlkene diamination represents one of the most straightforward strategies for 1,2-diamine derivatives synthesis. However, transition-metal-free 1,2-diamination of fluoroalkenes has been less studied. Here we report an intermolecular defluorinative vicinal diamination...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Newly synthesized sulfonamide derivatives explored for DNA binding, enzyme inhibitory, and cytotoxicity activities: a mixed computational and experimental analyses By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35047-35063DOI: 10.1039/D4RA06412G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nasima Arshad, Yasir Mehmood, Hammad Ismail, Fouzia Perveen, Aneela Javed, Pervaiz Ali Channar, Aamer Saeed, Sadia Naseem, Fatima NaseerThis work reports synthesis, characterization, DNA, enzyme binding and cytotoxicity activity of three 4-((3-arylthiazolo[3,4-d]isoxazol-5-yl)amino)benzene sulfonamide derivatives with a thaizaole(3,4-d)isoxazole-based fused ring heterocyclic system.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Design, synthesis, biological evaluation, and in silico studies of novel N-substituted-2-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazole-6-carboxamides as promising anticancer agents By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35323-35335DOI: 10.1039/D4RA04492D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Navid Dastyafteh, Manica Negahdaripour, Mohammad Hosein Sayahi, Mina Emami, Younes Ghasemi, Elham Safaei, Homa Azizian, Zahra Pakrouh Jahromi, Mehdi Asadi, Mohammad Reza Mohajeri-Tehrani, Fateme Zare, Minoo Shahidi, Zahra Pooraskari, Sayed Mahmoud Sajjadi-Jazi, Bagher Larijani, Mohammad Mahdavi, Sara RanjbarSynthesis and cytotoxicity evaluation of novel benzimidazoles were explained. The most potent derivative was subjected to cell cycle, apoptosis, and in silico investigations. Compound 5o proved to be a promising anticancer agent.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid A mild and convenient protocol for the synthesis of quinoxalin-2(1H)-ones and benzimidazoles By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35386-35390DOI: 10.1039/D4RA06887D, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhenbiao Luo, Mingyuan Wang, Guidong Jiang, Xinye Wang, Liang Zhao, Zhihui Hu, Honghe Li, Qing JiWe present a mild and simple method for the cyclization of N-protected o-phenylenediamines with carbonyl compounds in the presence of trifluoroacetic acid.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid N-doped carbon quantum dots for the selective detection of OCl− ions, bioimaging, and the production of Fe3O4 nanoparticles utilized in the synthesis of substituted imidazole By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35448-35459DOI: 10.1039/D4RA06474G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Namrata Priyadarshini Hota, Sathiyanarayanan Kulathu IyerNitrogen-doped quantum dots (NCQD) were synthesized by solvothermal means using o-phenylenediamine and L-tartaric acid.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Design, synthesis, and in vitro and in vivo biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35239-35254DOI: 10.1039/D4RA06704E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Heba A. Adawy, Samar S. Tawfik, Abdullah A. Elgazar, Khalid B. Selim, Fatma E. GodaIn response to the urgent need for new anti-proliferative agents, four novel series of triazolopyrimidine compounds (7a–e, 9a–d, 11a–f, and 13a–e) were synthesized and evaluated for in vitro and in vivo anticancer efficacy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Zeolitic imidazolate framework-67 in chitosan-grafted hydrogel as an effective catalyst for peroxymonosulfate activation to degrade antibiotics and dyes By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35628-35637DOI: 10.1039/D4RA06537A, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Atipong Nachaichot, Kunlarat Phonlakan, Supinya Nijpanich, Soraya Pornsuwan, Surangkhana BudsombatZeolitic imidazolate framework-67 (ZIF-67) was synthesized in situ in the hydrogel of chitosan-grafted poly(acrylic acid) (chitosan-g-PAA) to activate peroxymonosulfate (PMS) and degrade tetracycline (TC).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Complexes between 2,2'-azobis(2-methylpropionamidine) dihydrochloride (AAPH) and cucurbit[n]uril hosts modulate the yield and fate of photolytically-generated AAPH radicals By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35980-35991DOI: 10.1039/D4RA07150F, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Angie C. Forero-Girón, Mauricio Oyarzún, Kevin Droguett, Denis Fuentealba, Soledad Gutiérrez-Oliva, Barbara Herrera, Alejandro Toro-Labbé, Eduardo Fuentes-Lemus, Michael J. Davies, Camilo López-Alarcón, Margarita E. AliagaAAPH-cucurbit[n]uril systems were experimentally and theoretically studied. Radical yields formed upon photolysis of AAPH were altered by complexation with CB[8] in a stoichiometry-dependent manner, however, radical yields were not changed by CB[6].The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
mid Braj Mandal Yatra begins in Haryana’s Nuh amid tight security By www.thehindu.com Published On :: Mon, 22 Jul 2024 12:56:01 +0530 The Braj Mandal Yatra route spans over nearly 80 km and ends at Singar via the Jhir temple Full Article Other States
mid COP29 begins amid global headwinds By www.thehindu.com Published On :: Mon, 11 Nov 2024 21:20:13 +0530 As talks open, United Nations warns that Paris climate agreement’s goals ‘are in great peril’; re-election of Donald Trump as U.S. President has cast shadow on the summit; many world leaders have also skipped the meet where the primary focus is on increasing climate financing by wealthy nations Full Article Environment
mid 45,000 US dockworkers set to strike at midnight, impacting East and Gulf Coast ports By www.thehindubusinessline.com Published On :: Tue, 01 Oct 2024 09:45:00 +0530 The strike by members of the International Longshoremen's Association could cause 36 ports to shutter operations Full Article World
mid Yemen's Houthi rebels are looking to gain from continuing conflict in Middle East By www.thehindubusinessline.com Published On :: Wed, 02 Oct 2024 10:27:41 +0530 Recent Houthi attacks has again drawn attention to the Yemeni rebels and raised questions about their goals and strategies Full Article World
mid Pakistan to hike petrol prices amid economic turmoil By www.thehindubusinessline.com Published On :: Sat, 12 Oct 2024 12:33:40 +0530 Due to high smuggling and illegal trade, the country continues to suffer, and is dependent on international players for its energy security Full Article World
mid Maldives President Muizzu to take 50% salary cut amid growing economic strain By www.thehindubusinessline.com Published On :: Thu, 24 Oct 2024 19:29:51 +0530 The move was announced as part of special measures in his government’s ‘economic reform agenda’ Full Article World
mid Bangladesh ramps up payments to Adani Power amid power supply cuts By www.thehindubusinessline.com Published On :: Mon, 04 Nov 2024 19:53:10 +0530 Bangladesh is scrutinising its contract with Adani Power, as it is charging Bangladesh a rate nearly 27 per cent higher than those of India’s other private producers Full Article World
mid Fighting India lose 0-1 to formidable Iran in AFC U20 Asian Cup Qualifiers By www.thehindu.com Published On :: Sat, 28 Sep 2024 04:40:00 +0530 The top teams of the 10 groups, along with the five best second-place finishers, will qualify for the AFC U20 Asian Cup 2025 in China Full Article Football
mid Gold hits another high amid fading demand By www.thehindubusinessline.com Published On :: Fri, 12 Apr 2024 19:21:49 +0530 Demand for new jewellery has almost ceased as customers await a price drop after weeks of steady increases Full Article Gold & Silver