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Spatially isolated reactions in a complex array: using magnetic beads to purify and quantify nucleic acids with digital and quantitative real-time PCR in thousands of parallel microwells

Lab Chip, 2020, Advance Article
DOI: 10.1039/D0LC00069H, Paper
W. Hampton Henley, Nathan A. Siegfried, J. Michael Ramsey
Encoded beads carrying primer pairs for nucleic acid targets are used for sample preparation and multiplexed-in-space digital PCR quantification.
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Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

Lab Chip, 2020, 20,1621-1627
DOI: 10.1039/D0LC00304B, Paper
Fu Sun, Anurup Ganguli, Judy Nguyen, Ryan Brisbin, Krithika Shanmugam, David L. Hirschberg, Matthew B. Wheeler, Rashid Bashir, David M. Nash, Brian T. Cunningham
A 30-minute nucleic acid test for equine respiratory virus from nasal swab material, detected with a smartphone.
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Chiral Ru(II) complexes act as a potential non-viral gene carrier for directional transportation to the nucleus and cytoplasm

Metallomics, 2020, 12,504-513
DOI: 10.1039/C9MT00192A, Paper
Qiong Wu, Shuang-Yan Zhang, Si-Yan Liao, Jie-Qiong Cao, Wen-Jie Zheng, Li Li, Wen-Jie Mei
A novel approach has been proposed to develop a potent gene carrier system for enantioselectivity on the self-assembly of G-quadruplex DNA promoted by chiral Ru(II) complexes, and the different assembled nanostructures of cellular uptake to the nucleus and cytoplasm.
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[ASAP] ß-Cyclodextrin–NHC–Gold(I) Complex (ß-ICyD)AuCl: A Chiral Nanoreactor for Enantioselective and Substrate-Selective Alkoxycyclization Reactions

ACS Catalysis
DOI: 10.1021/acscatal.0c00127




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Podcast: Nuclear forensics, honesty in a sea of lies, and how sliced meat drove human evolution

Online News Editor David Grimm shares stories on the influence of governmental corruption on the honesty of individuals, what happened when our ancestors cut back on the amount of time spent chewing food, and how plants use sand to grind herbivores‘ gears.   Science’s International News Editor Rich Stone joins host Sarah Crespi to discuss his forensics story on how to track down the culprits after a nuclear detonation.   [Image: Miroslav Boskov]




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Next-generation cellphone signals could interfere with weather forecasts, and monitoring smoke from wildfires to model nuclear winter

In recent months, telecommunications companies in the United States have purchased a new part of the spectrum for use in 5G cellphone networks. Weather forecasters are concerned that these powerful signals could swamp out weaker signals from water vapor—which are in a nearby band and important for weather prediction. Freelance science writer Gabriel Popkin joins host Sarah Crespi to talk about the possible impact of cellphone signals on weather forecasting and some suggested regulations. In other weather news this week, Sarah talks with Pengfei Yu, a professor at Jinan University in Guangzhou, China, about his group’s work using a huge smoke plume from the 2017 wildfires in western Canada as a model for smoke from nuclear bombs. They found the wildfire smoke lofted itself 23 kilometers into the stratosphere, spread across the Northern Hemisphere, and took 8 months to dissipate, which line up with models of nuclear winter and suggests these fires can help predict the results of a nuclear war. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo.com Download the transcript (PDF)  Listen to previous podcasts. About the Science Podcast




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Detection of prostate-specific antigen in semen using DNA aptamers: an application of nucleic acid aptamers in forensic body fluid identification

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00371A, Paper
Tetsuya Satoh, Seiya Kouroki, Yusuke Kitamura, Toshihiro Ihara, Kazutoshi Matsumura, Susumu Iwase
In forensics, body fluid identification plays an important role because it aids in reconstructing the crime scene. Therefore, it is essential to develop simple and reliable techniques for body fluid...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rapid and colorimetric detection of nucleic acids based on entropy-driven circuit and DNAzyme mediated autocatalytic reaction

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00341G, Paper
Hongli Shi, Jianyuan Dai, fang Wang, Yushun Xia, Dan Xiao, Cuisong Zhou
In this work, a novel, rapid and enzyme-free colorimetric biosensor for nucleic acids detection has been developed based on entropy-driven circuit (EDC) and DNAzyme mediated autocatalytic reaction. Upon sensing of...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Structural Characterization of Individual a-Synuclein Oligomers Formed at Different Stages of Protein Aggregation by Atomic Force Microscopy-Infrared Spectroscopy

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00593




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[ASAP] Zirconium–Metalloporphyrin Frameworks–Luminol Competitive Electrochemiluminescence for Ratiometric Detection of Polynucleotide Kinase Activity

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c01262




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[ASAP] Tandem NMR and Mass Spectrometry Analysis of Human Nuclear Membrane Lipids

Analytical Chemistry
DOI: 10.1021/acs.analchem.9b05052




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[ASAP] Sequencing of Small DNA Fragments with Aggregated-Induced-Emission Molecule-Labeled Nucleotides

Analytical Chemistry
DOI: 10.1021/acs.analchem.0c00707




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[ASAP] Correction of <italic toggle="yes">Q</italic> Factor Effects for Simultaneous Collection of Elemental Analysis and Relaxation Times by Nuclear Magnetic Resonance

Analytical Chemistry
DOI: 10.1021/acs.analchem.9b05603




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[ASAP] Microscopic Analysis of Heterogeneous Nucleation of Nanoparticle Superstructures

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.0c01844




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[ASAP] Computational Evidence for Homonuclear Ge<sup>I</sup>Ge<sup>I</sup> Dative Bonds

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.9b11665




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[ASAP] Attracting Opposites: Promiscuous Ion-p Binding in the Nucleobases

The Journal of Physical Chemistry A
DOI: 10.1021/acs.jpca.0c02766




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Insight into the Unwrapping of the Dinucleosome

Soft Matter, 2020, Accepted Manuscript
DOI: 10.1039/D0SM00161A, Paper
Fatemeh Khodabandeh, Hashem Fatemi, Farshid Mohammad-Rafiee
Dynamics of nucleosomes, the building blocks of the chromatin, has crucial effects on expression, replication and repair of genomes in eukaryotes. Beside constant movements of nucleosomes by thermal fluctuations, ATP-dependent...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The end of strategic stability?: Nuclear weapons and the challenge of regional rivalries / Lawrence Rubin and Adam N. Stulberg, editors

Dewey Library - U263.E557 2018




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Wales and the bomb: the role of Welsh scientists and engineers in the British nuclear programme / John Baylis

Dewey Library - U264.5.G7 B39 2019




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Disarming Doomsday: the human impact of nuclear weapons since Hiroshima / Becky Alexis-Martin

Dewey Library - U263.A44 2019




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India's nuclear proliferation policy: the impact of secrecy on decision making, 1980-2010 / Gaurav Kampani

Dewey Library - UA840.K245 2020




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Power generation resumes at Kudankulam Nuclear Power plant

First unit was shut down on October 29 for the second time in a week for some tests.




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Six killed in blast near Kudankulam nuclear plant, security stepped up

Safety arrangements have been stepped up at the nuclear plant following the blast.




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Advances in human factors in energy : oil, gas, nuclear and electric power industries : proceedings of the AHFE 2017 International Conference on Human Factors in Energy: Oil, Gas, Nuclear and Electric Power Industries, July 17-21, 2017, The Westin Bonaven

International Conference on Human Factors in Energy (2017 : Los Angeles, Calif.),




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Extraction of nuclear and non-ferrous metals / Sujay Kumar Dutta, Dharmesh R. Lodhari

Dutta, Sujay Kumar, author




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[ASAP] Core–Shell C@Sb Nanoparticles as a Nucleation Layer for High-Performance Sodium Metal Anodes

Nano Letters
DOI: 10.1021/acs.nanolett.0c01257




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Double allylic defluorinative alkylation of 1,1-bisnucleophiles with (trifluoromethyl)alkenes: construction of all-carbon quaternary centers

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00121J, Research Article
Yingying Cai, Hao Zeng, Chuanle Zhu, Chi Liu, Guangying Liu, Huanfeng Jiang
Synthesis of symmetric gem-difluoroalkene substituted products bearing all-carbon quaternary centers via double allylic defluorinative alkylation of 1,1-bisnucleophiles with (trifluoromethyl)alkenes.
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Direct organocatalytic asymmetric Michael reaction of fluorine hemiaminal-type nucleophile to 4-nitro-5-styrylisoxazoles

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00348D, Research Article
Luyao Li, Bo Zhu, Huihui Fan, Zhiyong Jiang, Junbiao Chang
Herein, we report a chiral bifunctional thiourea catalyzed asymmetric Michael addition reaction between 2-(trifluoromethyl)oxazol-5(2H)-one as a direct C-2-position nucleophile to 4-nitro-5-styrylisoxazoles for the first time.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Ag2O-catalysed nucleophilic isocyanation: selective formation of less-stable benzylic isonitriles

Org. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QO00336K, Research Article
Taiga Yurino, Yuji Tange, Ryutaro Tani, Takeshi Ohkuma
Both primary and secondary benzylic isonitriles were exclusively produced by the Ag2O-catalysed reaction of benzylic phosphates and trimethylsilyl cyanide without formation of the thermodynamically favoured regioisomers, benzylic nitriles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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[ASAP] Nucleophilic (Radio)Fluorination of Redox-Active Esters via Radical-Polar Crossover Enabled by Photoredox Catalysis

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c03125




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[ASAP] Molecular Mechanism for the Suppression of Alpha Synuclein Membrane Toxicity by an Unconventional Extracellular Chaperone

Journal of the American Chemical Society
DOI: 10.1021/jacs.0c01894




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Cyber and Chemical, Biological, Radiological, Nuclear, Explosives Challenges: Threats and Counter Efforts / by Maurizio Martellini, Andrea Malizia

Online Resource




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Plant Nucleotide Metabolism: Biosynthesis, Degradation, and Alkaloid Formation


 

All organisms produce nucleobases, nucleosides, and nucleotides of purines and pyrimidines. However, while there have been a number of texts on nucleotide metabolism in microorganisms and humans, the presence of these phenomena in plant life has gone comparatively unexplored. This ground-breaking new book is the first to focus exclusively on the aspects of purine nucleotide metabolism and function that are particular to plants, making it a unique



Read More...




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UCL update their homepage

This week UCL have updated their homepage with a new design that I translated into XHTML, CSS, and Javascript.

UCL will gradually be updating other parts of their website as they move forward. You can read the UCL blog post about their new homepage and the history of the UCL homepage.

I was responsible for producing the XHTML, CSS, and Javascript that makes up the templates for this redesign. The members of UCL’s Web Services team then integrated the templates (and modified them as required) into their CMS.




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Trinuclear Mn2+/Zn2+ based microporous coordination polymers as efficient catalysts for ipso-hydroxylation of boronic acids

Dalton Trans., 2020, 49,5454-5462
DOI: 10.1039/D0DT00794C, Paper
Sanchay J. Bora, Rima Paul, Anurag Dutta, Shyam Goswami, Ankur K. Guha, Ashim J. Thakur
Two efficient catalysts based on trinuclear Mn(II)/Zn(II) clusters were synthesized and used for ipso-hydroxylation of phenylboronic acids into the corresponding phenols with excellent yields.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Templated syntheses of heterometal tungsten–cobalt–sulfur clusters with different nuclearities

Dalton Trans., 2020, 49,5523-5530
DOI: 10.1039/D0DT00765J, Paper
Jia-Ting Guo, Xu-Dong Chen
A series of heterometal tungsten–cobalt–sulfur clusters with different nuclearities have been synthesized rationally using a chelating template.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Retraction: Determination of chemical affinity of graphene oxide nanosheets with radionuclides investigated by macroscopic, spectroscopic and modeling techniques

Dalton Trans., 2020, 49,5741-5741
DOI: 10.1039/D0DT90074E, Retraction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Congcong Ding, Wencai Cheng, Yubing Sun, Xiangke Wang
The content of this RSS Feed (c) The Royal Society of Chemistry




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Structure and magnetic properties of a novel heteroheptanuclear metal string complex [Ni3Ru2Ni2(μ7-teptra)4(NCS)2](PF6)

Dalton Trans., 2020, Advance Article
DOI: 10.1039/D0DT00156B, Paper
Cheng-Chang Chiu, Ming-Chuan Cheng, Sheng-Hsiang Lin, Cheng-Wei Yan, Gene-Hsiang Lee, Mu-Chieh Chang, Tien-Sung Lin, Shie-Ming Peng
A novel heteroheptanuclear metal string complex was synthesized by using nickel and ruthenium metal ions to explore the electronic structure and magnetic property.
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Metal–metal bond formation of triplatinum cores with a silver(I) ion affording a heptanuclear cluster bearing four Pt–Ag bonds

Dalton Trans., 2020, Advance Article
DOI: 10.1039/D0DT01227K, Communication
Natsuki Yabune, Hiroshi Nakajima, Takanori Nishioka
A triplatinum complex with chelating NHC ligands reacts with Ag(I) and affords a heptanuclear cluster bearing four Ag–Pt bonds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Spin-frustration with two quasi-degenerated spin states of a copper(II) heptanuclear complex obtained from an amino acid ligand

Dalton Trans., 2020, Accepted Manuscript
DOI: 10.1039/C9DT04501E, Paper
Catiúcia Rodrigues Marcelino Oliveira Matos, Henrique Silva Jr, Dayenny D’Amato, Guilherme Guedes, Glaucio Braga Ferreira, Odivaldo Cambraia Alves, Filipe Barra de Almeida, Sergio Pinheiro, Acácio Souza, Flavio Garcia, Célia Machado Ronconi
The Cu(II) heptanuclear complex (Cu7atac) was synthesised using the hydrated amino acid ligand 2-(5-amino-1H-1,2,4-triazol-3-yl)acetic acid (Hatac.H2O). Single crystal X-ray diffraction analysis revealed a μ3-hydroxo bridged Cu(II) heptanuclear complex, consisting of...
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The Nuclear Nonproliferation Treaty / Kelsey Davenport

Online Resource




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Families-- beyond the nuclear ideal / edited by Daniel Cutas and Sarah Chan

Online Resource




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MSc - Nuclear Science and Engineering: South West Nuclear Hub, University of Bristol

£Attractive: South West Nuclear Hub, University of Bristol
For more latest jobs and jobs in South West England visit brightrecruits.com



  • South West England

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Building and System Integrator: Belgian Nuclear Research Centre (SCK-CEN)

€Attractive: Belgian Nuclear Research Centre (SCK-CEN)
For more latest jobs and jobs in Belgium visit brightrecruits.com




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Cryogenics Engineer: Belgian Nuclear Research Centre (SCK-CEN)

€Attractive: Belgian Nuclear Research Centre (SCK-CEN)
For more latest jobs and jobs in Belgium visit brightrecruits.com





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High-power RF engineer for accelerator applications: Belgian Nuclear Research Centre (SCK-CEN)

€Attractive: Belgian Nuclear Research Centre (SCK-CEN)
For more latest jobs and jobs in Belgium visit brightrecruits.com




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Power Converter Engineer: Belgian Nuclear Research Centre (SCK-CEN)

€Attractive: Belgian Nuclear Research Centre (SCK-CEN)
For more latest jobs and jobs in Belgium visit brightrecruits.com




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LLRF expert (Low-Level RF): Belgian Nuclear Research Centre (SCK-CEN)

€Attractive: Belgian Nuclear Research Centre (SCK-CEN)
For more latest jobs and jobs in Belgium visit brightrecruits.com




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Director of the INFN Gran Sasso National Laboratory – Assergi (L’Aquila) Italy: Istituto Nazionale di Fisica Nucleare (INFN)

€Attractive: Istituto Nazionale di Fisica Nucleare (INFN)
For more latest jobs and jobs in Italy visit brightrecruits.com