London : printed for A. Strahan, and T. Cadell jun. and W. Davies, (successors to Mr. Cadell,) in the Strand, 1797.

London : printed for A. Strahan, T. Cadell jun. and W. Davies, 1800.

London : And J. Balfour, and W. Creech, Edinburgh, 1805.

London : printed for A. Strahan, T. Cadell and W. Davies, 1803.

Manchester : printed by S. Russell, 1806.

London : J. Johnson, 1807.

London : F.C. and J. Rivington, 1813.

Dunbar : printed by and for G. Miller, 1817.

Edinburgh : And for C. Elliot and T. Kay, London, 1789.

Edinburgh : Bell & Bradfute, 1813.

Stuttgart : F. Enke, 1895.

Rockville, Maryland : National Institute on Drug Abuse, 1985.

In Canada, financial advisors and dealers by provincial securities commissions, and those self-regulatory organizations charged with direct regulation over investment dealers and mutual fund dealers, respectively to collect and maintain Know Your Client (KYC) information, such as their age or risk tolerance, for investor accounts. With this information, investors, under their advisor's guidance, make decisions on their investments which are presumed to be beneficial to their investment goals. Our unique dataset is provided by a financial investment dealer with over 50,000 accounts for over 23,000 clients. We use a modified behavioural finance recency, frequency, monetary model for engineering features that quantify investor behaviours, and machine learning clustering algorithms to find groups of investors that behave similarly. We show that the KYC information collected does not explain client behaviours, whereas trade and transaction frequency and volume are most informative. We believe the results shown herein encourage financial regulators and advisors to use more advanced metrics to better understand and predict investor behaviours.

The large volumes of Sentinel-1 data produced over Europe are being used to develop pan-national ground motion services. However, simple analysis techniques like thresholding cannot detect and classify complex deformation signals reliably making providing usable information to a broad range of non-expert stakeholders a challenge. Here we explore the applicability of deep learning approaches by adapting a pre-trained convolutional neural network (CNN) to detect deformation in a national-scale velocity field. For our proof-of-concept, we focus on the UK where previously identified deformation is associated with coal-mining, ground water withdrawal, landslides and tunnelling. The sparsity of measurement points and the presence of spike noise make this a challenging application for deep learning networks, which involve calculations of the spatial convolution between images. Moreover, insufficient ground truth data exists to construct a balanced training data set, and the deformation signals are slower and more localised than in previous applications. We propose three enhancement methods to tackle these problems: i) spatial interpolation with modified matrix completion, ii) a synthetic training dataset based on the characteristics of real UK velocity map, and iii) enhanced over-wrapping techniques. Using velocity maps spanning 2015-2019, our framework detects several areas of coal mining subsidence, uplift due to dewatering, slate quarries, landslides and tunnel engineering works. The results demonstrate the potential applicability of the proposed framework to the development of automated ground motion analysis systems.

You've got exactly four hours left to take advantage of these heavily discounted prices.

Matilda McCrear was just 2 when she was captured and brought to Alabama on the "Clotilda"

The monster of modernity must be slowed.

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

A three-judge panel from the 9th U.S. Circuit Court of Appeals ruled against a proposed plan that would have paid certain student-athletes as much as $5,000 annually in deferred compensation.

A $59 million investment in software developer Social Solutions aims to ease the flow of data among schools and social service providers.

Source: Infobae - El cambio climático es probablemente el mayor desafío ambiental y social que enfrenta la humanidad, y que fue generado por el ser humano. Es un problema global que se resuelve en forma global, en donde existen muchos matices que hacen difícil el consenso entre los países respecto a las decisiones que deben tomarse. Sin embargo, todos reconocen el siguiente principio como marco de discusión: principio de responsabilidades comunes pero diferenciadas. Este principio reconoce que todos los países tienen responsabilidad común de solucionar el problema, aunque no todos en el mismo nivel y grado, ya que históricamente los países desarrollados han contaminado más a efecto de construir sus economías que aquellos que están en vías de desarrollo. Y no todos los países tienen la misma capacidad y recursos para enfrentar la problemática.

Routine screening of potentially abused children with hepatic transaminases has been recommended, using a threshold of 80 IU/L to determine the need for further testing, but practice is variable, and this threshold has not been validated.

This study identified abdominal injury in a significant fraction of potentially abused children with transaminases >80 IU/L. (Read the full article)

Suboptimal brain development and increased risk of cognitive deficits are well documented in very low birth weight children. Supplementation with docosahexaenoic acid and arachidonic acid has been associated with positive cognitive effects.

This follow-up study of a randomized controlled trial of supplementation with docosahexaenoic acid and arachidonic acid to very low birth weight infants is the first report on both cognition and brain macrostructure measured with MRI. No cognitive or neuroanatomical effects were detected at 8 years. (Read the full article)

Recent studies highlight the abundance of commensal coagulase-negative staphylococci (CoNS) on healthy skin. Evidence suggests that CoNS actively shape the skin immunological and microbial milieu to resist colonization or infection by opportunistic pathogens, including methicillin resistant Staphylococcus aureus (MRSA), in a variety of mechanisms collectively termed colonization resistance. One potential colonization resistance mechanism is the application of quorum sensing, also called the Accessory Gene Regulator (agr) system, which is ubiquitous among staphylococci. Common and rare CoNS make autoinducing peptides (AIPs) that function as MRSA agr inhibitors, protecting the host from invasive infection. In a screen of CoNS spent media we found that Staphylococcus simulans, a rare human skin colonizer and frequent livestock colonizer, released potent inhibitors of all classes of MRSA agr signaling. We identified three S. simulans agr classes, and have shown intraspecies cross-talk between non-cognate S. simulans agr types for the first time. The S. simulans AIP-I structure was confirmed, and the novel AIP-II and AIP-III structures were solved via mass spectrometry. Synthetic S. simulans AIPs inhibited MRSA agr signaling with nanomolar potency. S. simulans in competition with MRSA reduced dermonecrotic and epicutaneous skin injury in murine models. Addition of synthetic AIP-I also effectively reduced MRSA dermonecrosis and epicutaneous skin injury in murine models. These results demonstrate potent anti-MRSA quorum sensing inhibition by a rare human skin commensal, and suggest that cross-talk between CoNS and MRSA may be important in maintaining healthy skin homeostasis and preventing MRSA skin damage during colonization or acute infection.

Türkiye devleti ile uluslararası alanda terör örgütü olarak kabul edilen PKK arasındaki çözüm sürecinin çökmesi, Temmuz 2015’te çatışmaların yeniden başlaması ve daha sonra derinleşen şiddet sarmalı, yeni bir çözüm sürecinin inşasını hiç olmadığı kadar gerekli kılıyor.

DOVER, DE – Delaware Insurance Commissioner Trinidad Navarro is pleased to announce that there will be another decrease in workers’ compensation insurance rates, effective December 1, 2019. “I am delighted to approve a decrease in workers’ compensation rates in Delaware for the third year in a row,” stated Commissioner Navarro. “These continued decreases mean significant […]

Workplace Safety Program saves $7.6 million for participants The Delaware Department of Insurance has analyzed new filings from the state’s top writers of workers’ compensation insurance after announcing the third consecutive year of decreased rates in November. The top writers represent nearly 10,000 companies that hold policies within the state. Policyholders of these companies will […]

Border Roads Organisation has completed the construction of road from Dharchula to Lipulekh on China Border.

Andhra Pradesh Chief Minister YS Jaganmohan Reddy has announced Rs one crore as compensation to the families of those who died because of exposure to a toxic gas that leaked overnight at a chemical...

Political observers see the fielding of Doval as the Prime Minister’s assertion on the issue of developments linked to changes in the citizenship law which have triggered protests across the country.

The 16-year-old Verma takes over from New Zealand's Suzie Bates, who had been the top batter since October 2018 after wresting the spot from West Indies captain Stafanie Taylor.

The Ministry of External Affairs organises the yatra from June-September each year through two different routes -- Lipulekh Pass (Uttarakhand) and Nathu La Pass (Sikkim).

According to the Pradhan Mantri Jan Dhan Yojana (PMJDY) website, the total number of RuPay cards issued so far stands at over 290 million.

Digital transactions have gained new heights in the month of March as India announced a lockdown due to coronavirus. The total value of Real Time Gross Settlement (RTGS) transactions also witnessed a spike.

The development also shows the government's push for digital technology has enabled people to access banking services even when the pandemic spread its tentacles.

Minister for road transport and highways (MoRTH) Nitin Gadkari said for the first time that the border is finally connected by roads.

Banks to pay Rs 1.06 crore to customers for online banking frauds

The NCAA enforcement staff, in its reply to Kansas regarding charges of five Level I rules violations, said coach Bill Self and assistant Kurtis Townsend "embraced, welcomed and encouraged" Adidas' influence to help high-profile recruits sign at KU.

Christina Belone, Talisa Budder and Matt Woody to take part on second day of 85^th edition of the prestigious event