The proteomic landscape of in vitro cultured endothelial cells across vascular beds  Nature.com

Novel FFPE proteomics method suggests prolactin induced protein as hormone induced cytoskeleton remodeling spatial biomarker | Communications Biology  Nature.com

Identifying proteomic risk factors for cancer using prospective and exome analyses of 1463 circulating proteins and risk of 19 cancers in the UK Biobank  Nature.com

Optimizing differential expression analysis for proteomics data via high-performing rules and ensemble inference  Nature.com

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications  Nature.com

Serum proteomics reveal APOE-ε4 -dependent and APOE-ε4 -independent protein signatures in Alzheimer’s disease  Nature.com

quantms: a cloud-based pipeline for quantitative proteomics enables the reanalysis of public proteomics data  Nature.com

A multi-species benchmark for training and validating mass spectrometry proteomics machine learning models  Nature.com

Deep Plasma Proteomics with Data-Independent Acquisition: Clinical Study Protocol Optimization with a COVID-19 Cohort  ACS Publications

Proteomic analysis of the combined effects of cannabigerol and 3- O -ethyl ascorbic acid on kinase-dependent signalling in UVB-irradiated human keratinocytes  Nature.com

The Chicago Transit Authority (CTA) today proposed a $2.16 billion operating budget that keeps fares at current levels, delivers more bus and rail service hours than provided in 2019, and fuels new and ongoing investments to either expand or modernize existing infrastructure, while also evolving current systems to meet modern transit riding needs.

The Chicago Transit Authority today welcomed about 75 residents and businesses from the Far South Side to the Red Line Extension (RLE) Fall Community Meet & Greet Event. Held at the site of the future Michigan Red Line station on E. 116th Street and S. Michigan Ave., CTA and RLE contractor Walsh-VINCI Transit Community Partners welcomed RLE project supporters.

(Mon, Feb 19 2024 to TBD) The west entrance to the Harlem (O’Hare branch) Blue Line station on Higgins Avenue and the adjacent Park and Ride lot will temporarily close.

(Fri, Jul 28 2023 10:00 PM to TBD) West platform at Wilson is temporarily closed. Board/exit all trains on the east platform.

(Fri, Jul 28 2023 10:00 PM to TBD) The temporary Argyle station on Argyle St is closed and a new temp Argyle station open 1-2 blks north, with staffed entrances on Foster Ave and Winona St.

(Fri, Jul 28 2023 10:00 PM to TBD) Temp Bryn Mawr stn entrances on B'way & Bryn Mawr Av closed; new temp Bryn Mawr stn open 75ft east of old stn under viaduct. Only 95th-bnd srvc at new temp stn.

(Tue, Oct 10 2023 to TBD) #1 buses will no longer start or end their trips at Union Station (Adams/Canal). Trips begin/end at Desplaines/Harrison. Boarding at Union Station is unchanged.

(Tue, Oct 10 2023 to TBD) #121 buses will no longer board on Jackson west of Canal (Stop A). Board buses in the Union Station Transit Center, just south of the current stop, at Stop C.

The post Rape crisis worker dismissed over gender-critical views awarded £69k appeared first on Personnel Today.

The first class of Planet Money Summer School starts off with a field trip. With the help of a cow, two economists, and three cute animals, we learn what a stock is and how stocks are priced, and we begin to see the psychological forces that make prices move up and down on the stock market. Keep an eye out throughout for our big theme for the course this summer: risk and reward. | Watch this Tik Tok to learn more and subscribe to our weekly newsletter here.

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Even if you don't own stocks, there are a lot of reasons to care about investing. We meet some of the folks left out of the stock market who deploy sophisticated economic thinking, even creating their own alternate financial systems. Our professors help us understand how consumption smoothing and life-cycle hypothesis apply to personal finance. And we meet the creator of the 401(k). | Watch this Tik Tok to learn more and subscribe to our weekly newsletter here.

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Southeast Asia is one of the biggest growth markets for American wheat. Where did this taste for wheat come from and who is responsible?

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It's listener question time. We've got answers about "free" shipping, full employment, when a raise isn't a raise, Taylor Swift, crypto seizures and our very own Micro-Face comic. | Subscribe to our weekly newsletter here.

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An American business owner with employees in Russia extracts her colleagues from the country. | Subscribe to our weekly newsletter here.

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Ballpark vendors share their strategies and other secrets to selling the most hot dogs at baseball games. | Subscribe to our weekly newsletter here.

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After many, many delays, the Micro-Face comic book is here! And we answer the burning question: Why did it take so long to make a comic book? | Come see Planet Money Live in NYC on May 10th! One night only. Tickets on sale here. And buy our now-ready Micro-Face comic book.

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Soon after the mass shooting at Columbine High School in 1999, leaders of the National Rifle Association held a conference call to craft their response. Secret tapes from this call obtained by NPR's Investigations team reveal how the NRA developed what would become their standard response after decades of school shootings. | Listen to the original Up First episode: n.pr/nratapes

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What transforms a regular object into a collectible? At our live show earlier this month, we went on a journey through collectibles history. And we had a goal: to turn our Micro-Face comic book into the most collectible item of all time. | Bid on our collectible Micro-Face comic book here!

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This episode, Micro-Face: The Musical. A full concert recording of a one-of-a-kind Planet Money superhero musical, taped during our recent live show at the Roulette Theater in Brooklyn, New York.

Here's more from our project We Buy A Superhero.

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Sand. It's in buildings, windows, your cell phone. But there isn't enough in the world for everyone. And that's created a dangerous black market.

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This episode was first released as a bonus episode for Planet Money+ listeners last month. We're sharing it today for all listeners. To hear more episodes like this one and support NPR in the process, sign up for Planet Money+ at plus.npr.org.

Planet Money+ supporters: we'll have a fresh bonus episode for you next week!

"Save aggressively for retirement when you're young." "The stock market is a sure-fire long-term bet." "Fixed-rate mortgages are better than adjustable-rate mortgages." Popular financial advice like this appears in all kinds of books by financial thinkfluencers. But how does that advice stack up against more traditional economic thinking?

That's the question Yale economist James Choi set out to answer in a paper called Popular Personal Financial Advice Versus The Professors. In this interview, he tells Greg Rosalsky what he found. Their talk marks another edition of Behind The Newsletter, in which Greg shares conversations with policy makers and economists who appear in the Planet Money newsletter.

Subscribe to the newsletter at https://www.npr.org/newsletter/money.

Read more about James Choi's paper here: https://www.npr.org/sections/money/2022/09/06/1120583353/money-management-budgeting-tips

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A lot of computing pioneers were women. For decades, the number of women in computer science was growing. But in 1984, something changed.

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A great economics paper does two things. It takes on a big question, and it finds a smart way to answer that question.

But some papers go even further. The very best papers have the power to change lives.That was the case for three economists we spoke to: Nancy Qian, Belinda Archibong, and Kyle Greenberg.

They all stumbled on important economics papers at crucial moments in their careers, and those papers gave them a new way to see the world. On today's show - how economics papers on the Pentecostal church in Ghana, the Vietnam war draft, and the price of butter in Sweden shaped the courses of three lives.

This episode was produced by Sam Yellowhorse Kesler. It was edited by Keith Romer. Sierra Juarez checked the facts, and it was mastered by Natasha Branch with help from Gilly Moon. Jess Jiang is our acting executive producer.

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For episode 2 of Planet Money Summer School, we are talking strategy. You have your million dollar business idea, and maybe some money in your pocket to get it up and running. But now you enter into a crowded market. You have to deal with competition.

So, what can you do to make sure your product is a success? That was the conundrum facing the Starbury. It was a basketball shoe with a celebrity endorsement, that had to go up against THE basketball shoe with THE celebrity endorsement: the Air Jordan. Our first story is about the ways in which the Starbury succeeded and failed in taking on a juggernaut.

Then, we will hear a story about trying to avoid the dangers of "perfect" competition. Two companies making almost identical handbells learn that the key to their success lies in convincing customers how different they really are.

Find all episodes of Planet Money Summer School here.

The series is hosted by Robert Smith and produced by Max Freedman. Our project manager is Julia Carney. This episode was edited by Keith Romer and engineered by Robert Rodriguez. The show is fact-checked by Sierra Juarez. Planet Money's executive producer is Alex Goldmark.

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We here at Planet Money love economics papers. And that is also the case for so many of the economists we speak with. For them, new research can explain something they have always wondered about, or make them see something they have never noticed before. And it inspires their own work.

So, to bring that same sense of discovery to you, the listener, today we are dedicating our show to a special experiment. A new way to share some of the most fascinating, clever and surprising economics papers in a segment we're calling: The Econ Paper Club.

On today's show, we read the econ papers so you don't have to. We take a joyous romp through some of the most fascinating ideas floating around economics right now. And we find that some of those fascinating ideas are about some of the biggest things in life: the careers we choose, the expectations that come with parenting and what one eminent economist calls 'greedy jobs.'

This episode was hosted by Erika Beras and Kenny Malone. It was produced by Sam Yellowhorse Kesler and James Sneed. It was edited by Molly Messick. It was fact-checked by Sierra Juarez, and engineered by Robert Rodriguez. Alex Goldmark is our executive producer.

Help support Planet Money and get bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

Always free at these links: Apple Podcasts, Spotify, Google Podcasts, NPR One or anywhere you get podcasts.

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Usually, the first class that an MBA student takes is accounting. That involves, yes, equations and counting widgets...but it's more than that. Inside the simple act of accounting is a revolutionary way of thinking not just about a business, but about the world. A universe where all the forces are in balance. Accounting gives you a sixth sense–one that can help you determine whether your business will survive or fail.

In this class, you'll learn the basics of accounting, and uncover its origins. We'll introduce you to the man who helped it spread around the world. He was a monk, a magician, and possibly the boyfriend of Leonardo da Vinci.

Is accounting... sexy?

Yes. Yes it is.

Find all episodes of Planet Money Summer School here.

This series is hosted by Robert Smith, and produced by Max Freedman. Our project manager is Julia Carney. This episode was edited by Sally Helm and engineered by Robert Rodriguez. The show is fact-checked by Sierra Juarez. Planet Money's executive producer is Alex Goldmark.

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"It's difficult to control everything," says our guest professor for this week, Santiago Gallino. "What is not difficult is to plan for everything." Today we venture into the sphere of business that masters the planning, and backup planning: operations management.

It's more than just predicting a bottleneck and imagining a solution, because there's always a bottleneck to clear. It's about modeling, and weighing the costs of messing up vs. missing out. For instance, take a newspaper vendor who has to decide how many newspapers to sell tomorrow morning. Do they buy fewer, knowing that they'll sell out–and then miss out on potential revenue from papers not sold? Or do they order more than they expect to sell, just in case–and eat the cost of a few unsold papers? This type of trade-off applies to all kinds of businesses, and Gallino talks us through how to choose.

The only certainty in this life is uncertainty. But we are certain you will come out of this episode feeling better prepared for your future business. And fortunately, there are no bottlenecks in podcasting.

The series is hosted by Robert Smith and produced by Max Freedman. Our project manager is Julia Carney. This episode was edited by Alex Goldmark and engineered by James Willetts. The show is fact-checked by Sierra Juarez.

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The Nobel-prize winning economist Simon Kuznets once analyzed the world's economies this way — he said there are four kinds of countries: developed, underdeveloped, Japan... and Argentina.

If you want to understand what happens when inflation really goes off the rails, go to Argentina. Annual inflation there, over the past year, was 124 percent. Argentina's currency, the peso, is collapsing, its poverty rate is above 40 percent, and the country may be on the verge of electing a far right Libertarian president who promises to replace the peso with the dollar. Even in a country that is already deeply familiar with economic chaos, this is dramatic.

In this episode, we travel to Argentina to try to understand: what is it like to live in an economy that's on the edge? With the help of our tango dancer guide, we meet all kinds of people who are living through record inflation and political upheaval. Because even as Argentina's economy tanks, its annual Mundial de Tango – the biggest tango competition in the world – that show is still on.

This episode was hosted by Amanda Aronczyk and Erika Beras. It was produced by Sam Yellowhorse Kesler with help from James Sneed. It was engineered by Maggie Luthar, fact-checked by Sierra Juarez, and edited by Molly Messick. Alex Goldmark is Planet Money's executive producer.

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Note: There is swearing in this episode.

In 2017, The University of Minnesota asked comedian Maria Bamford to give their commencement speech. But the University may not have known what it was in for. In her speech, Bamford told the crowd of graduates how much the university offered to pay her (nothing), her counteroffer ($20,000), and the amount they settled on ($10,000), which (after taxes and fees, etc.) she gave away to students in the audience to pay down their student loans.

Maria Bamford is a big believer in full disclosure of her finances, a philosophy she's adopted after decades in a Debtors Anonymous support group. In meetings, she learned important financial tips and tricks to go from thousands of dollars in debt to her current net worth of $3.5 million (a number which, true to her philosophy, she will share with anyone).

She spoke with us about her financial issues, how she recovered, and why she believes in total financial transparency, even when it makes her look kinda bad.

Disclaimer: Planet Money is not qualified or certified to give financial advice. And Maria is not a spokesperson for Debtors Anonymous in any way.

This show was hosted by Kenny Malone and Mary Childs. It was produced by Emma Peaslee, edited by Jess Jiang, fact-checked by Sierra Juarez, and engineered by Neisha Heinis. Alex Goldmark is Planet Money's executive producer.

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Union membership in the U.S. has been declining for decades. But, in 2022, support for unions among Americans was the highest it's been in decades. This dissonance is due, in part, to the difficulties of one important phase in the life cycle of a union: setting up a union in the first place. One place where that has been particularly clear is at the Volkswagen plant in Chattanooga, Tennessee.

Back in 2008, Volkswagen announced that they would be setting up production in the United States after a 20-year absence. They planned to build a new auto manufacturing plant in Chattanooga.

Volkswagen has plants all over the world, all of which have some kind of worker representation, and the company said that it wanted that for Chattanooga too. So, the United Auto Workers, the union that traditionally represents auto workers, thought they would be able to successfully unionize this plant.

They were wrong.

In this episode, we tell the story of the UAW's 10-year fight to unionize the Chattanooga plant. And, what other unions can learn from how badly that fight went for labor.

This episode was hosted by Amanda Aronczyk and Nick Fountain. It was produced by Willa Rubin. It was engineered by Josephine Nyounai, fact-checked by Sierra Juarez, and edited by Keith Romer. Alex Goldmark is our executive producer.

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What if you could borrow money on the cheap and use it to pay for just about anything? The U.S. government can, and does, with U.S. Treasuries. But the market for Treasuries might be more fragile than we know.

In this episode, Yesha Yadav of Vanderbilt Law School explains why.

This episode was first published as a bonus episode for our Planet Money+ listeners. Today we're making it available for everyone. To hear more episodes like this, and to hear Planet Money and The Indicator without sponsor messages, support the show by signing up for Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

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There's this fundamental question in economics that has proven really hard to answer: What's a good way to help people out of poverty? The old-school way was to fund programs that would support very particular things, like buying cows for a village, giving people business training, or building schools.

But over the past few decades, there has been a new idea: Could you help people who don't have money by ... just giving them money? We covered this question in a segment of This American Life that originally ran in 2013. Economists who studied the question found that giving people cash had positive effects on recipients' economic and psychological well-being. Maybe they bought a cow that could earn them money each week. Maybe they could replace their grass roofs with metal roofs that didn't need fixing every so often.

The success of just giving people in poverty cash has spawned a whole set of new questions that economists are now trying to answer. Like, if we do just give money, what's the best way to do that? Do you just give it all at once? Or do you dole it out over time? And it turns out... a huge new study on giving cash was just released and it's got a lot of answers.

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Dynamic pricing is an increasingly common phenomenon: You can see it when Uber prices surge during rainy weather, or when you're booking a flight at the last minute or buying tickets to your favorite superstar's concert. On an earnings call last week, Wendy's ignited a minor controversy by suggesting it would introduce dynamic pricing in its restaurants, but the company quickly clarified that it wasn't planning on using it for "surge pricing."

One place you hardly ever see dynamic pricing? American supermarkets.

Why is that? Why shouldn't the prices for meat or bread or produce go down as they get older? Why does all the milk in the store cost the same, even when the "sell by" dates are weeks apart? Wouldn't a little more flexibility around prices be better for customers and help reduce waste?

Professors Robert Evan Sanders and Ioannis (Yannis) Stamatopoulus had similar questions. So they set out to discover what was keeping supermarkets from employing a more dynamic approach, and what might convince them it was time for a change ... in pricing.

This episode was hosted by Amanda Aronczyk and Nick Fountain. It was produced by Willa Rubin and edited by Keith Romer. It was engineered by Valentina Rodríguez Sánchez and fact-checked by Sierra Juarez.

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(Note: This episode originally ran in 2023.)

Union membership in the U.S. has been declining for decades. But, in 2022, support for unions among Americans was the highest it's been in decades. This dissonance is due, in part, to the difficulties of one important phase in the life cycle of a union: setting up a union in the first place. One place where that has been particularly clear is at the Volkswagen plant in Chattanooga, Tennessee.

Back in 2008, Volkswagen announced that they would be setting up production in the United States after a 20-year absence. They planned to build a new auto manufacturing plant in Chattanooga.

Volkswagen has plants all over the world, all of which have some kind of worker representation, and the company said that it wanted that for Chattanooga too. So, the United Auto Workers, the union that traditionally represents auto workers, thought they would be able to successfully unionize this plant.

They were wrong.

In this episode, we tell the story of the UAW's 10-year fight to unionize the Chattanooga plant. And, what other unions can learn from how badly that fight went for labor.

This episode was hosted by Amanda Aronczyk and Nick Fountain. It was produced by Willa Rubin. It was engineered by Josephine Nyounai, fact-checked by Sierra Juarez, and edited by Keith Romer. Alex Goldmark is our executive producer.

Help support Planet Money and get bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

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When the vape brand Juul first hit the market back in 2015, e-cigarettes were in a kind of regulatory limbo. At the time, the rules that governed tobacco cigarettes did not explicitly apply to e-cigarettes. Then Juul blew up, fueled a public health crisis over teen vaping, and inspired a regulatory crackdown. But when the government finally stepped in to solve the problem of youth vaping, it may have actually made things worse.

Today's episode is a collaboration with the new podcast series "Backfired: the Vaping Wars." You can listen to the full series at audible.com/Backfired.

This episode was hosted by Alexi Horowitz-Ghazi and Leon Neyfakh. It was produced by Emma Peaslee and edited by Jess Jiang with help from Annie Brown. It was fact checked by Sofia Shchukina and engineered by Cena Loffredo. Alex Goldmark is Planet Money's executive producer.

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Episodes each Wednesday through labor day. Find all the episodes from this season here. And past seasons here. And follow along on TikTok here for video Summer School.

Once upon a time, every business was a small business. It was run by the owner, maybe the spouse and the kids. Maybe they borrowed money from friends and relatives, but there was only so big it could get. Then came what can only be described as the big bang of economics. Over the span of a few decades, people figured out a way for businesses to sell ownership shares – otherwise known as stocks – and let people trade those shares. There was suddenly money to buy machines and expand.

Today, we head to the Netherlands around the year 1600. First, we'll visit the bridge in Amsterdam where some of the first stock trading took place. Then we track down the Dutch water company that's the source of the oldest "living" bond. It's the origin of stocks and bonds and the stock market and it leads directly to many of the financial innovations that we still have today.

This series is hosted by Robert Smith and produced by Audrey Dilling. Our project manager is Devin Mellor. This episode was edited by Planet Money Executive Producer Alex Goldmark and fact-checked by Sofia Shchukina.

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The Federal Reserve raised interest rates to get inflation under control. One side effect is that taking out a mortgage to buy a home has gotten very expensive. That's especially a problem for some homeowners who managed to get a lower mortgage rate years ago. They have a sort of... champagne problem. Or, "golden handcuffs" as it's called.

These homeowners may find they are "locked in" to their current home. In order to move to a new home, they have to take out a new mortgage at a much higher rate. It is one of the many problems plaguing the housing market right now.

The Fed is expected to start cutting rates next week. Will the golden handcuff mess finally start to unlock? And what does it mean for people looking to buy their first home?

On today's episode: We go deep into the golden handcuff problem and why it matters for everyone (including non-homeowners). We have FOMO about a big economic symposium in Jackson Hole, Wyoming. And we contemplate how to pronounce one of the most important interest rates in the economy: The IORB.

This episode was hosted by Kenny Malone and Alexi Horowitz-Ghazi. It was produced by Sean Saldana. It was edited by Jess Jiang and fact-checked by Sierra Juarez. Engineering by Cena Loffredo. Alex Goldmark is Planet Money's executive producer.

Help support Planet Money and hear our bonus episodes by subscribing to Planet Money+ in Apple Podcasts or at plus.npr.org/planetmoney.

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Today we have a guest episode from 99 Percent Invisible.

It is about White Castle, the burger chain. Even if you haven't visited, you have tasted its influence because, as we will learn in this episode, White Castle is really the proto-burger chain.

Our friends at the excellent podcast 99 Percent Invisible bring us the origin story of White Castle and trace its influence on the business of fast food, and on American eating habits. The story is about one man who had an idea for a world where you could get a slider anywhere in the country and get the same tasty, onion-y quality each time. Think of this as a forebear of the modern global economy of sameness.

This episode is hosted by Roman Mars and reported by Mackenzie Martin. It was produced by Jeyca Maldonado-Medina, and edited by Joe Rosenberg. Mix and sound design by Martín Gonzalez. Music by Swan Real with additional music by Jenny Conlee, Nate Query, and John Neufeld. Fact-checking by Graham Hacia. Kathy Tu is 99 Percent Invisible's executive producer. Kurt Kohlstedt is their digital director, and Delaney Hall is their senior editor.

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In the early 90s, teenagers LeAlan Jones and Lloyd Newman recorded a week of their lives on Chicago's South Side. Working with StoryCorps founder Dave Isay, LeAlan and Lloyd produced a documentary they called Ghetto Life 101, one of the most acclaimed programs in public radio history. In remembrance of Lloyd, who died this week, we bring you a special presentation of Ghetto Life 101.

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50 years ago, most of the nation was glued to "gavel-to-gavel" coverage of the Senate Watergate hearings that would uncover major abuses of power by the Nixon administration. In this episode – how a decision to speak up blew the lid off the largest political scandal in American history.

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