i Stimulation of ABCB4/MDR3 ATPase activity requires an intact phosphatidylcholine lipid By www.jlr.org Published On :: 2020-12-01 Martin PrescherDec 1, 2020; 61:1605-1616Research Articles Full Article
i A novel phosphoglycerol serine-glycine lipodipeptide of Porphyromonas gingivalis is a TLR2 ligand By www.jlr.org Published On :: 2020-12-01 Frank C. NicholsDec 1, 2020; 61:1645-1657Research Articles Full Article
i PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids By www.jlr.org Published On :: 2020-12-01 Hideaki KugeDec 1, 2020; 61:1747-1763Research Articles Full Article
i Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort By www.jlr.org Published On :: 2020-12-01 Chiara PavanelloDec 1, 2020; 61:1784-1788Patient-Oriented and Epidemiological Research Full Article
i Bioavailability and spatial distribution of fatty acids in the rat retina after dietary omega-3 supplementation By www.jlr.org Published On :: 2020-12-01 Elisa VidalDec 1, 2020; 61:1733-1746Research Articles Full Article
i Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase By www.jlr.org Published On :: 2020-12-01 Marco De GiorgiDec 1, 2020; 61:1675-1686Research Articles Full Article
i Gene Networks and Pathways for Plasma Lipid Traits via Multi-tissue Multi-omics Systems Analysis By www.jlr.org Published On :: 2020-12-23 Montgomery BlencoweDec 23, 2020; 0:jlr.RA120000713v1-jlr.RA120000713Research Articles Full Article
i A review of phosphatidate phosphatase assays By www.jlr.org Published On :: 2020-12-01 Prabuddha DeyDec 1, 2020; 61:1556-1564Reviews Full Article
i Human glucocerebrosidase mediates formation of xylosyl-cholesterol by {beta}-xylosidase and transxylosidase reactions. By www.jlr.org Published On :: 2020-12-23 Daphne E.C. BoerDec 23, 2020; 0:jlr.RA120001043v1-jlr.RA120001043Research Articles Full Article
i Spatial profiling of gangliosides in mouse brain by mass spectrometry imaging By www.jlr.org Published On :: 2020-12-01 Douglas A. AndresDec 1, 2020; 61:1537-1537Images in Lipid Research Full Article
i Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice By www.jlr.org Published On :: 2020-12-01 Nicholas D. LeBlondDec 1, 2020; 61:1697-1706Research Articles Full Article
i LDL apheresis as an alternate method for plasma LPS purification in healthy volunteers and dyslipidemic and septic patients By www.jlr.org Published On :: 2020-12-01 Auguste DargentDec 1, 2020; 61:1776-1783Research Articles Full Article
i Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging By www.jlr.org Published On :: 2020-12-23 Astrid M. MoermanDec 23, 2020; 0:jlr.RA120000974v1-jlr.RA120000974Research Articles Full Article
i Cholesterol transport between red blood cells and lipoproteins contributes to cholesterol metabolism in blood By www.jlr.org Published On :: 2020-12-01 Ryunosuke OhkawaDec 1, 2020; 61:1577-1588Research Articles Full Article
i Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition By www.jlr.org Published On :: 2020-12-01 Genta KakiyamaDec 1, 2020; 61:1629-1644Research Articles Full Article
i The anti-tubercular activity of simvastatin is mediated by cholesterol-driven autophagy via the AMPK-mTORC1-TFEB axis By www.jlr.org Published On :: 2020-12-01 Natalie BruinersDec 1, 2020; 61:1617-1628Research Articles Full Article
i Accessible cholesterol is localized in bacterial plasma membrane protrusions By www.jlr.org Published On :: 2020-12-01 Michael E. AbramsDec 1, 2020; 61:1538-1538Images in Lipid Research Full Article
i Identification of unusual phospholipids from bovine heart mitochondria by HPLC-MS/MS By www.jlr.org Published On :: 2020-12-01 Junhwan KimDec 1, 2020; 61:1707-1719Research Articles Full Article
i Deletion of lysophosphatidylcholine acyltransferase3 in myeloid cells worsens hepatic steatosis after a high fat diet By www.jlr.org Published On :: 2020-12-11 Thibaut BourgeoisDec 11, 2020; 0:jlr.RA120000737v1-jlr.RA120000737Research Articles Full Article
i Lipid metabolism dysregulation in diabetic retinopathy By www.jlr.org Published On :: 2020-12-23 Julia V BusikDec 23, 2020; 0:jlr.TR120000981v1-jlr.TR120000981Thematic Reviews Full Article
i Human CETP lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice By www.jlr.org Published On :: 2020-12-09 Aloïs DusuelDec 9, 2020; 0:jlr.RA120000704v1-jlr.RA120000704Research Articles Full Article
i Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation By www.jlr.org Published On :: 2020-12-09 Anja JaeschkeDec 9, 2020; 0:jlr.RA120001141v1-jlr.RA120001141Research Articles Full Article
i Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice By www.jlr.org Published On :: 2020-12-01 Abudukadier AbuliziDec 1, 2020; 61:1565-1576Research Articles Full Article
i SCD1 promotes lipid mobilization in subcutaneous white adipose tissue By www.jlr.org Published On :: 2020-12-01 Ying ZouDec 1, 2020; 61:1589-1604Research Articles Full Article
i Structure dynamics of ApoA-I amyloidogenic variants in small HDL increase their ability to mediate cholesterol efflux By www.jlr.org Published On :: 2020-11-17 Oktawia NilssonNov 17, 2020; 0:jlr.RA120000920v1-jlr.RA120000920Research Articles Full Article
i rHDL modelling and the anchoring mechanism of LCAT activation By www.jlr.org Published On :: 2020-12-02 Tommaso LaurenziDec 2, 2020; 0:jlr.RA120000843v1-jlr.RA120000843Research Articles Full Article
i Insights on the kinetics and dynamics of the furin-cleaved form of PCSK9 By www.jlr.org Published On :: 2020-11-17 Carlota OleagaNov 17, 2020; 0:jlr.RA120000964v1-jlr.RA120000964Research Articles Full Article
i Apolipoprotein C3 and apolipoprotein B colocalize in proximity to macrophages in atherosclerotic lesions in diabetes By www.jlr.org Published On :: 2020-12-08 Jenny E. KanterDec 8, 2020; 0:jlr.ILR120001217v1-jlr.ILR120001217Images in Lipid Research Full Article
i Distinct patterns of apolipoprotein C-I, C-II and C-III isoforms are associated with markers of Alzheimers disease By www.jlr.org Published On :: 2020-12-11 Yueming HuDec 11, 2020; 0:jlr.RA120000919v1-jlr.RA120000919Research Articles Full Article
i Generation and validation of a conditional knockout mouse model for the study of the Smith-Lemli-Opitz Syndrome By www.jlr.org Published On :: 2020-11-17 Babunageswararao KanuriNov 17, 2020; 0:jlr.RA120001101v1-jlr.RA120001101Research Articles Full Article
i Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control By www.jlr.org Published On :: 2020-12-17 Stacey N KeenanDec 17, 2020; 0:jlr.RA120001126v1-jlr.RA120001126Research Articles Full Article
i Adiponectin forms a complex with atherogenic LDL and inhibits its downstream effects By www.jlr.org Published On :: 2020-11-03 Akemi KakinoNov 3, 2020; 0:jlr.RA120000767v1-jlr.RA120000767Research Articles Full Article
i Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures By www.jlr.org Published On :: 2020-12-01 Gerhard LiebischDec 1, 2020; 61:1539-1555Special Report Full Article
i Multi-modal Functional Imaging of Brown Adipose Tissue By www.jlr.org Published On :: 2020-11-18 Amanda D.V. MacCannellNov 18, 2020; 0:jlr.ILR120001204v1-jlr.ILR120001204Images in Lipid Research Full Article
i Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis [Genomics and Proteomics] By www.jbc.org Published On :: 2020-12-04T00:06:05-08:00 Amyloid fibrils are polymeric structures originating from aggregation of misfolded proteins. In vivo, proteolysis may modulate amyloidogenesis and fibril stability. In light chain (AL) amyloidosis, fragmented light chains (LCs) are abundant components of amyloid deposits; however, site and timing of proteolysis are debated. Identification of the N and C termini of LC fragments is instrumental to understanding involved processes and enzymes. We investigated the N and C terminome of the LC proteoforms in fibrils extracted from the hearts of two AL cardiomyopathy patients, using a proteomic approach based on derivatization of N- and C-terminal residues, followed by mapping of fragmentation sites on the structures of native and fibrillar relevant LCs. We provide the first high-specificity map of proteolytic cleavages in natural AL amyloid. Proteolysis occurs both on the LC variable and constant domains, generating a complex fragmentation pattern. The structural analysis indicates extensive remodeling by multiple proteases, largely taking place on poorly folded regions of the fibril surfaces. This study adds novel important knowledge on amyloid LC processing: although our data do not exclude that proteolysis of native LC dimers may destabilize their structure and favor fibril formation, the data show that LC deposition largely precedes the proteolytic events documentable in mature AL fibrils. Full Article
i Problem Notes for SAS®9 - 66438: You see the message "The informat $ could not be loaded, probably due to insufficient memory" after attempting to insert data into a MySQL database By Published On :: Wed, 2 Sep 2020 10:39:14 EST For data that is being loaded from a SAS Stored Process Server, an insertion process might fail to a MySQL database with a warning, as well as an error message that says "During insert: Incorrect datetime value " Full Article BASE+Base+SAS
i Problem Notes for SAS®9 - 66537: SAS Customer Intelligence Studio becomes non-responsive when you delete a calculated variable from the Edit Value dialog box By Published On :: Tue, 1 Sep 2020 14:25:38 EST In SAS Customer Intelligence Studio, you might notice that the user interface becomes unresponsive, as shown below: imgalt="SAS Customer Intelligence Studio UI becomes unresponsive" src="{fusion_66537 Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
i Problem Notes for SAS®9 - 66539: A new calculated variable that you create in the Edit Value dialog box is not available for selection in SAS Customer Intelligence Studio By Published On :: Tue, 1 Sep 2020 13:44:23 EST In SAS Customer Intelligence Studio, you can choose to create a new calculated variable in the Edit Value dialog box when you populate a treatment custom detail. Following creation of the new calculated Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
i Problem Notes for SAS®9 - 66544: You cannot clear warnings for decision campaign nodes in SAS Customer Intelligence Studio By Published On :: Tue, 1 Sep 2020 13:41:53 EST In SAS Customer Intelligence Studio, you might notice that you cannot clear warnings for decision campaign nodes by selecting either the Clear Warnings option or the Clear All Warnin Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
i Problem Notes for SAS®9 - 66527: Updating counts in a Link node in SAS Customer Intelligence Studio produces the error "Link: MAIQService:executeFastPath:" By Published On :: Tue, 1 Sep 2020 10:53:01 EST In SAS Customer Intelligence Studio, the following error is displayed when you update a new Link node in a diagram: imgalt="Link: MAIQService:executeFastPath:" src="{fusion_665 Full Article CAMPAIGNSDO+SAS+Customer+Intelligence+St
i Problem Notes for SAS®9 - 66540: SAS Management Console and SAS Data Integration Studio might return the message "table failed to update" when you use the Update Metadata tool By Published On :: Tue, 1 Sep 2020 09:06:18 EST You encounter this issue when the table metadata matches the data source. In this scenario, no metadata update is required. Full Article MGMTCONSOLE+SAS+Management+Console
i Problem Notes for SAS®9 - 66542: The initial loading of a rule set and a rule flow takes significantly longer in SAS Business Rules Manager 3.3 compared with release 3.2 By Published On :: Mon, 31 Aug 2020 16:35:05 EST In SAS Business Rules Manager 3.3, the initial loading of a rule set and a rule flow takes significantly longer than it does in release 3.2. When this problem happens, long time gaps are evident in the local Full Article BRLSTBNDL+SAS+Business+Rules+Manager
i Problem Notes for SAS®9 - 66524: SAS Visual Data Builder uses the wrong SAS Application Server for previewing and scheduling By Published On :: Mon, 31 Aug 2020 12:14:44 EST If you have configured more than one SAS Application Server, then SAS Visual Data Builder might unexpectedly use the wrong application server when you preview or schedule queries. This problem occurs even though you h Full Article VISANLYTBNDL+SAS+Visual+Analytics
i Problem Notes for SAS®9 - 66487: Authentication to the CAS server fails with the error "Access denied..." when initiated on a SAS/CONNECT server in a Microsoft Windows environment By Published On :: Mon, 31 Aug 2020 10:33:55 EST You might see the following error messages: "ERROR: Connection failed. Server returned: SAS Logon Manager authentication failed: Access denied." and "ERROR: Unable to connect to Cloud Analytic Services host-name on port 5570. Veri Full Article CONNECT+SAS/CONNECT
i Problem Notes for SAS®9 - 55516: Opening the Edit Action Columns dialog box requires that you wait up to a minute to display a window By Published On :: Fri, 28 Aug 2020 11:23:00 EST Editing and/or saving an action column can take up to a minute to display a window. There are no workarounds identified at this time. Full Article SCDOFR+SAS+Visual+Scenario+Designer
i Problem Notes for SAS®9 - 66509: Several procedures in SAS/STAT Software and SAS/QC Software generate incorrect results when an OBSMARGINS= data set is used By Published On :: Fri, 28 Aug 2020 08:58:34 EST If the response variable is in the CLASS statement variable list before the class variables that also appear in the MODEL statement, and an OM-data-set is used, least squares means results for several of the statistical procedures are incorrect. Full Article STAT+SAS/STAT
i Problem Notes for SAS®9 - 66391: Opening a database table returns a Segmentation Violation when you use the Metadata LIBNAME engine (META) By Published On :: Wed, 26 Aug 2020 16:39:25 EST You might receive a Segmentation Violation when opening a database table in SAS. The SAS Log contains the error and traceback: ERR Full Article METADATASRV+SAS+Metadata+Server
i Problem Notes for SAS®9 - 58465: SAS Life Science Analytics Framework 4.6 - Group membership removal fails with an exception for Process Flows that exist in the Recycle Bin By Published On :: Wed, 26 Aug 2020 16:27:10 EST In SAS Life Science Analytics Framework 4.6, group membership removal fails with an exception if a user is set as assignee, a candidate, or a notification recipient in a user task for a Process Flow . The Process Full Article LSAFOFR+SAS+Life+Science+Analytics+Frame
i Problem Notes for SAS®9 - 33449: An error might occur when you use SAS 9 BULKLOAD= and BULKEXTRACT= options to load data to or extract data from the HP Neoview database on the HP Itanium platform By Published On :: Wed, 26 Aug 2020 16:21:08 EST An error might occur when you use the SAS 9 BULKLOAD= and BULKEXTRACT= options load data to or extract data from HP Neoview on the HP Itanium platform. The problem occurs because Hewlett-Packard changed the name of one of Full Article NEOVIEW+SAS/ACCESS+Interface+to+HP+Neovi
i Problem Notes for SAS®9 - 48028: Custom Time Frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels By Published On :: Wed, 26 Aug 2020 16:17:42 EST In SAS Merchandise Financial Planning, custom time frame-based data versions do not aggregate correctly when referenced in worksheets with standard hierarchy levels. The data does not aggregate correctly from l Full Article MMFINANCPLN+SAS+Merchandise+Financial+Pl
