As the pandemic ebbed in China, alumni from the region raised more than $2.1 million to send crucial protective gear to New York healthcare workers.

Fundraising efforts, along with a generous donation from Beyond Meat, founded by Ethan Brown ’08, helps restaurant P.S. Kitchen, owned by April Tam Smith ’10 and Graham Smith ’21, provide meals to healthcare workers.

Matt Egan is in the presenter chair this week as he chats about Black Friday and the changing face of online retail with acting editor at Macworld UK, David Price. Then online editor at Techworld.com Scott Carey talks Facebook and its recent issues with fake news and Chinese censorship (12:00). Finally, online editor at Computerworld UK Tamlin Magee brings us up to date with the Government's Autumn Statement and what it means for the technology sector (26:00).  

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Large numeric values consisting of 16 digits in SAS might be incorrect when written to Hadoop for columns defined with the BIGINT data type.  This problem was introduced in SAS 9

In SAS Data Integration Studio, the columns that you select to include in the target table in a Business Rules transformation appear in the Selected columns area in a random order. Th

Diabetes is now a pandemic disease. Moreover, a large number of people with prediabetes are at risk for developing frank diabetes worldwide. Both type 1 and type 2 diabetes increase the risk of atherosclerotic cardiovascular disease (CVD). Even with statin treatment to lower LDL cholesterol, patients with diabetes have a high residual CVD risk. Factors mediating the residual risk are incompletely characterized. An attractive hypothesis is that remnant lipoprotein particles (RLPs), derived by lipolysis from VLDL and chylomicrons, contribute to this residual risk. RLPs constitute a heterogeneous population of lipoprotein particles, varying markedly in size and composition. Although a universally accepted definition is lacking, for the purpose of this review we define RLPs as postlipolytic partially triglyceride-depleted particles derived from chylomicrons and VLDL that are relatively enriched in cholesteryl esters and apolipoprotein (apo)E. RLPs derived from chylomicrons contain apoB48, while those derived from VLDL contain apoB100. Clarity as to the role of RLPs in CVD risk is hampered by lack of a widely accepted definition and a paucity of adequate methods for their accurate and precise quantification. New specific methods for RLP quantification would greatly improve our understanding of their biology and role in promoting atherosclerosis in diabetes and other disorders.

George A. Bray
Apr 1, 2014; 37:950-956
Current Concepts of Type 2 Diabetes Prevention

George A. Bray
Apr 1, 2014; 37:950-956
Current Concepts of Type 2 Diabetes Prevention

The ambitious immigration overhaul package that Congress is studying has drawn criticism from conservatives who say it offers amnesty to lawbreakers, and from immigration advocates who say it will not do enough to bring millions of people out of the shadows.

Nothing beats beautifully roasted vegetables caramelized in their own sugar content to accompany a simple roast dinner or even on their own with a nice salad. The addition of perfumed lemon thyme and macadamia gives a nice touch.

Told from two points of view: Drake: Most guys like their dads. Most guys aren't the son of the literal devil. When Daddy Dearest tells me its unseemly for the last living son of the Lord of Hell to be unmarried, I hate to think who he has in mind. Until, I remember I'm technically already married. Yeah, she's human and I was all of eight at the time. But, still counts. Now I just need to get my wife to Hell for a meet and greet with Pops and send her back home. Except, our marriage won't technically be legit until it's consummated. And I don't know that I want to send her home... Wren: Most girls live normal lives. Most girls aren't married to the devil's son. There is something weirdly familiar about the new guy next door, but I can't place it. Then a weird little demon thing turns up in my room to tell me a prince of Hell wishes for an audience with me. Oh, yeah. And, apparently - while I'm not even eighteen yet - he's my husband? So, I find myself stuck in Hell with a husband. And, I guess I don't hate it as much as I thought I would. There's always something going on and things to discover. And soon, I don't know that I want to go home.

Leipzig : Engelmann, 1904.

Bonnae : Typis Joan. Frid. Abshoven, 1790.

Paris : O. Doin, 1881.

[London] : printed by C. and J. Adlard, [1843]

Edinburgh : Oliver & Boyd, 1862.

Amstelodami : Typis A. Wolfgang, 1674.

Spanking new stadiums in Los Angeles and Las Vegas unveiled in prime time. Business as usual, and you really can't blame the NFL for that. “The release of the NFL schedule is something our fans eagerly anticipate every year, as they look forward with hope and optimism to the season ahead,” Commissioner Roger Goodell said.

Multi-Class Incremental Learning (MCIL) aims to learn new concepts by incrementally updating a model trained on previous concepts. However, there is an inherent trade-off to effectively learning new concepts without catastrophic forgetting of previous ones. To alleviate this issue, it has been proposed to keep around a few examples of the previous concepts but the effectiveness of this approach heavily depends on the representativeness of these examples. This paper proposes a novel and automatic framework we call mnemonics, where we parameterize exemplars and make them optimizable in an end-to-end manner. We train the framework through bilevel optimizations, i.e., model-level and exemplar-level. We conduct extensive experiments on three MCIL benchmarks, CIFAR-100, ImageNet-Subset and ImageNet, and show that using mnemonics exemplars can surpass the state-of-the-art by a large margin. Interestingly and quite intriguingly, the mnemonics exemplars tend to be on the boundaries between different classes.

Yushu Shi, Michael Martens, Anjishnu Banerjee, Purushottam Laud.

Source: Bayesian Analysis, Volume 14, Number 3, 677--702.

Abstract:
Dirichlet process mixture (DPM) models provide flexible modeling for distributions of data as an infinite mixture of distributions from a chosen collection. Specifying priors for these models in individual data contexts can be challenging. In this paper, we introduce a scheme which requires the investigator to specify only simple scaling information. This is used to transform the data to a fixed scale on which a low information prior is constructed. Samples from the posterior with the rescaled data are transformed back for inference on the original scale. The low information prior is selected to provide a wide variety of components for the DPM to generate flexible distributions for the data on the fixed scale. The method can be applied to all DPM models with kernel functions closed under a suitable scaling transformation. Construction of the low information prior, however, is kernel dependent. Using DPM-of-Gaussians and DPM-of-Weibulls models as examples, we show that the method provides accurate estimates of a diverse collection of distributions that includes skewed, multimodal, and highly dispersed members. With the recommended priors, repeated data simulations show performance comparable to that of standard empirical estimates. Finally, we show weak convergence of posteriors with the proposed priors for both kernels considered.

Caernarfon, where the discovery was made, was key to Edward I's conquest of the Welsh

The missionary who lived in the house during the mid-1800s delivered vaccinations to locals during a smallpox epidemic

Fears around the pandemic are causing sleep patterns to change and strange dreams to linger in people’s memories

The 18th-century Edinburgh factory once produced a million bottles a week

This rapid and efficient method to prepare highly purified recombinant adeno-associated viruses (rAAVs) is based on binding of negatively charged rAAV capsids to an anion-exchange resin that is pH dependent.

An additional column will be added to the CST610 CSV report, "Discr_Full_Value_Margin". The new field will include the total of discretionary and full-value margin, including designated delivery margin.

For the full text of this advisory, please click here.

“It's not the end; it's not even the beginning of the end; but it is perhaps the end of the beginning”. Churchill's famous wartime speech after the battle of El Alamein in November 1942 was an ambiguous rallying cry. After all, by saying it was only the beginning, he was suggesting that there could be worse to come.

USA Gymnastics, which develops the U.S. Olympic team, reportedly failed to inform authorities of numerous allegations regarding sexual abuse by coaches.

Chorioamnionitis is associated with preterm birth and an increased risk of common adverse outcomes of prematurity, including early-onset sepsis and neurodevelopmental impairment. The effect of chorioamnionitis on postnatal immune function and risk of late-onset infection is unknown.

Chorioamnionitis, which complicates many preterm births, is independently associated with a significantly reduced risk of late-onset sepsis in preterm infants. The findings suggest that chorioamnionitis may modulate the development of postnatal immunity in a clinically significant manner. (Read the full article)

Chorioamnionitis (CAM) is a major risk factor for early-onset neonatal sepsis. The Committee on the Fetus and Newborn recommends extending the duration of antimicrobial therapy in neonates exposed to CAM and intrapartum antibiotics if laboratory data are abnormal, even if culture results are sterile.

When managed by using a strategy similar to recent Committee on the Fetus and Newborn guidelines, a large number of term and late-preterm infants exposed to CAM who had sterile blood culture findings were treated with prolonged antibiotic therapy, subjected to additional invasive procedures, and had prolonged hospitalization. (Read the full article)

In very preterm infants, outcomes depend not only on the degree of immaturity, but also on the underlying pathologies that trigger preterm delivery. Studies that have addressed this issue have provided unclear results.

Patterns of outcomes differ between maternal hypertension and chorioamnionitis: hypertension is associated with greater risks for bronchopulmonary dysplasia and retinopathy of prematurity, and lower risks for brain injury, necrotizing enterocolitis, early-onset sepsis. For mortality, the effect changes across gestational age weeks. (Read the full article)

Being bullied can lead to adverse physical and mental health outcomes. Individuals who experience a sudden traumatic event often have short-term disturbances in their sleep patterns. Ongoing trauma may result in extended periods of sleep disruption.

Being bullied in elementary school predicts parasomnias, such as nightmares and night terrors, years later. General practitioners, pediatricians, parents, and teachers may consider parasomnias as potential signs of being bullied. (Read the full article)

Sleep disorders are common in children and adolescents and have a substantial negative impact on daily life and school performance. Long-term evaluations of the efficacy and safety of pharmacologic treatment options for sleep disorders are lacking in pediatric patients.

These 2 studies provide the first evaluation of the effectiveness and safety of eszopiclone in children and adolescents with insomnia associated with ADHD. Data presented here encompass longer-term (up to 1 year) pediatric exposure to eszopiclone. (Read the full article)

Children with cystic fibrosis demonstrate gas exchange abnormalities and increased respiratory loads during sleep independent of lung function, age, and BMI. Assessment of breathing patterns during sleep provides an opportunity for detection of early lung disease progression.

Children with cystic fibrosis demonstrated increased respiratory loads and gas exchange abnormalities during sleep compared with controls. Based on these findings, sleep assessment in this patient population can identify markers for the early detection of lung disease progression. (Read the full article)

Anna-Maree Manciet is one of the estimated 164 million adult gamers. But for the Pennsylvania College of Technology alum, gaming is much more than entertainment. It’s a source of goodwill, both for herself and countless others. Since graduating from Penn College in 2013, Manciet’s video game prowess has led to personal healing, a thriving career and nearly $88,000 raised for St. Jude Children’s Research Hospital in Memphis, Tennessee.

Penn State and the Palmer Museum of Art mourn the loss of dear friend, generous donor, and loyal champion John P. Driscoll, who died from complications due to COVID-19 on Friday, April 10. Driscoll, owner of Driscoll Babcock Galleries in New York, was a longtime friend and supporter of the Palmer Museum and will be remembered for his role as a leader, gracious mentor and trusted adviser, as well as for the expansive gifts he made to the collection and to his alma mater, Penn State.

Stuckeman School graduate student Debora Verniz, who is a doctoral candidate in architecture, has been awarded the 2020 Alumni Association Dissertation Award from the Graduate School at Penn State for her research work in planning affordable housing structures in low-income areas.

Penn State’s College of Agricultural Sciences is staying connected to alumni during the COVID-19 pandemic by moving its monthly Alumni Society board meetings and other alumni activities online.

In this Q&A, Alumna Julia Mauro recounts in this Q&A how her role as an active-duty registered in the U.S. Navy has turned into fighting on a different kind of front-lines: the fight against the coronavirus pandemic.

Linda and Clifton Merchant met at Penn State Behrend and were married for 58 years. A new endowed legacy fund honors Linda Merchant and her time at the college.

Meaghan Paige, a women’s fashion brand started by a Penn State Brandywine alumna, is supporting the local community by offering free, handmade cloth face masks during the novel coronavirus pandemic.

Penn State alumnus and author Paul Levine's latest novel, "Cheater's Game," focuses on the college admissions scandal.

OMNIvision works behind the scenes at TeenStreet, OM’s international youth congress, providing top quality video for thousands of teens.

Mark Alpert made a generous gift $200,000 in memory of his late wife, Claire, to establish the Mark E. and Claire L. Alpert Graduate Fellowship in the Department of Civil and Environmental Engineering at Penn State.