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Engineering sulfated polysaccharides and silk fibroin based injectable IPN hydrogels with stiffening and growth factor presentation abilities for cartilage tissue engineering

Biomater. Sci., 2024, 12,2067-2085
DOI: 10.1039/D3BM01466E, Paper
Akansha Dixit, Aman Mahajan, Rakshita Saxena, Saptomee Chakraborty, Dhirendra S. Katti
In this study, we combined the β-sheet mediated self-stiffening ability of silk with growth factor presenting ability of sulphated carboxymethyl cellulose in an injectable interpenetrating network hydrogel for repair of articular cartilage defects.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Design, manufacturing and testing of a green non-isocyanate polyurethane prosthetic heart valve

Biomater. Sci., 2024, 12,2149-2164
DOI: 10.1039/D3BM01911J, Paper
Open Access
Sofia F. Melo, Alicia Nondonfaz, Abdelhafid Aqil, Anna Pierrard, Alexia Hulin, Céline Delierneux, Bartosz Ditkowski, Maxime Gustin, Maxime Legrand, Bibian M. E. Tullemans, Sanne L. N. Brouns, Alain Nchimi, Raoul Carrus, Astrid Dejosé, Johan W. M. Heemskerk, Marijke J. E. Kuijpers, Jan Ritter, Ulrich Steinseifer, Johanna C. Clauser, Christine Jérôme, Patrizio Lancellotti, Cécile Oury
Non-isocyanate polyurethanes (NIPUs) were developed and tested in vitro. Prosthetic heart valves made of NIPU were designed and manufactured. NIPUs showed low thrombogenicity and the produced valves performed well in terms of hydrodynamics.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Pfizer ramps up Indian R&D and manufacturing, says Meenakshi Nevatia, MD

Pfizer is shifting its oncology and chemotherapy product lines from Australia to Gujarat and aims to increase the share of local products in the Indian market.




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Asset-light approach: EV start-ups turn to micro-factories to cut costs, enhance flexibility

Micro-factories are closer to the market, require less capital investment, and are faster to set up




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Govt may soon standardise mobile screen guards to protect domestic manufacturing

The Centre losses crores of rupees due to unorganised screen guard imports from China



  • Mobiles & Tablets

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Samsung to invest in smart manufacturing capability, research and development in India

We will continue our investment to bring the optimised and or smart factory to the Noida facilities, says Samsung Electronics President and Head of Mobile eXperience Business T M Roh



  • Mobiles & Tablets

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Foxconn to start manufacturing iPhones in Karnataka by April 2024

The company has already paid 30% of the land cost to the Karnataka Industrial Areas Development Board




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Indkal Technologies licenses Acer brand to manufacture and sell mobile phones 

The agreement will see Acer designing, manufacturing, and distributing smartphones under its brand, focusing on models priced between ₹15,000 and ₹50,000




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The Hugo Barra factor in Xiaomi




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Google Pixel 9 Pro Fold Review | Blends software expertise with AI in a new form factor

The Pixel 9 Pro Fold not only marks Google’s foray into the foldable market in India, but also aims to redefine user expectations




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Apple to open retail stores in Bengaluru, Pune; starts manufacturing entire iPhone 16 series locally in India

Apple announced plans to open four new retail stores in India, the iPhone-maker also announced plans to start manufacturing the entire iPhone 16 lineup locally




fact

The design factor

Quirky, inventive and fun products for the home and office find space at Chromakey Designs as Suvasini Sridharan finds out




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Gold-plated artefacts for your home




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After SpaceX's requests, Taiwanese suppliers move manufacturing abroad, sources say

Elon Musk’s SpaceX asked Taiwanese suppliers to transfer manufacturing off the island, leading to some relocating portions of their supply chain




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Gilead’s Kite adds cell therapy manufacturing capacity




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Out of the sea and into the factory for Acasti’s heart drug ingredient

Acasti picks CordenPharma to extract omega-3s from krill




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Theracos becomes increasingly reliant on contract manufacturing as its drug advances

Piramal sites on different continents have become involved in producing Theracos’s diabetes treatment




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Sea, land, factory: 3 tales of pharmaceutical outsourcing

Drugs can be made by more than just chemical synthesis. Here are stories of three from the sea, the land, and yes, the factory




fact

Moderna opens mRNA manufacturing facility




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CSB issues video, factual update of Husky Superior refinery explosion




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Realme DIZO partners with OEL to manufacture products in India

Realme DIZO and Optiemus Electronics have partnered to make smartwatches and audio wearables in India




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Thomson invests ₹50 crore in Noida plant for audio speakers manufacturing

With a focus on capturing a 10% market share by 2028, Thomson’s CEO, Avneet Singh Marwah, has revealed ambitious expansion plans for the brand’s speaker range, aiming to offer over 80 models within the next three years




fact

One dead in major blaze at chemical factory in West Bengal’s Madhyamgram

Several people suffered severe burn injuries; workers were trapped inside the factory as firefighters struggled to reach them; with smoke engulfing the whole area, panic sparked among local residents




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Wanted: Manufacturing whizzes to work on Tesla Motor's Model 3




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Fadnavis calls Sharad Pawar ‘director of fake narrative factory’, says Maharashtra is No 1 in industrialisation




fact

Factors that will guide the markets this week

A host of macroeconomic data announcements, the last batch of September quarter earnings, global trends, and trading activity of foreign investors will be the major driving factors for the equity market this week, according to analysts. Equity markets would remain closed on Friday for Guru Nanak Jayanti. "India is set to release CPI and IIP data on November 12, with WPI data expected on November 14.




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Factory output up 3.1% in September

India's industrial production expanded by 3.1 per cent in September, mainly due to improvement in the manufacturing sector, according to official data released on Tuesday. The factory output, measured in terms of the Index of Industrial Production (IIP), witnessed a growth of 6.4 per cent in September 2023.




fact

The cool factor




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World Environment Day: Biodegradable tableware manufactured from agricultural waste is making inroads into the market

On this World Environment Day, a look at the boom in biodegradable cutlery and crockery made from agricultural residue



  • Life & Style

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10 useless fact on me, because I am bored

I am sorry that I have been gone for a pretty long time but now I am back so yeah

1- my birdthay is 21 July
2- My colour eye is blue
3- I freaking love reading
4- when I was younger I told my mother that in the future I want a library be a part of my house
5- i hate math, I wish that this never exist
6 - i am obsed with vampire, but I am scare of blood
7- I freaking love, witchcraft
8- Before I was hating art because I was unable to drawn something, but Gerard made me like this
9- I have a collection of stuffy
10- I am deep down in love with the MCRmy, you guys are incredible always cheer up even that we don't know each other

bonus : i am famous now XD look at this: https://www.facebook.com/505322182/videos/10157492150367183/
at 0:54 sec you can see me ( I am the girl with eh black parade jacket :P)

<3




fact

Heineken factory caught up in Brazil land dispute

Spring water case an example of kind of legal tangle that can await foreign investors




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Rabindranath Tagore’s Birth Anniversary: Some Facts About The Famous Bengali Poet And Novelist

Rabindranath Tagore, a popular Bengali-poet, artist, musician, Ayurveda researcher and polymath was born on 7 May 1861. He is often referred to as Gurudev, Kabiguru and Biswakabi by his admirers. During the late 19th century and early 20th century, he extensively




fact

Beta-thalassemia: Causes, Symptoms, Risk Factors, Treatment and Prevention

Thalassemia is a group of inherited blood disorders that has a similar characteristic: defective and reduced production of haemoglobin, the iron-containing protein in red blood cells that helps in carrying oxygen throughout the body. Beta-thalassemia (BT) is one of




fact

Centre issues fresh guidelines for restarting factories post-COVID-19 lockdown

For context, the nationwide lockdown is scheduled to end on May 17 but Centre has allowed reopening of industries in non-hotspot areas with some conditions.




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The Hard Facts of the Grimms' Fairy Tales: Expanded Edition.

Online Resource




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EPA awards City of Rockford $275,000 to clean up former Rockford Watch Factory, Lloyds Hearing Building

For Immediate Release No. 20-OPA-042




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Dubuque, Iowa, Bakery Earns EPA 2019 ENERGY STAR® Manufacturing Plant Certification

Environmental News  FOR IMMEDIATE RELEASE




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Coronavirus: The sex toy manufacturer making NHS gear

The BBC speaks to unexpected sources who are supplying PPE amid coronavirus shortages.




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Elon Musk says Tesla will &#39;immediately&#39; leave California after coronavirus shutdowns forced the company to close its main car factory

In a tweet Saturday morning, Tesla's chief executive said it would file a lawsuit against county officials over not being able to run its factory.





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Kruppel-like factor 3 (KLF3) suppresses NF-{kappa}B-driven inflammation in mice [Immunology]

Bacterial products such as lipopolysaccharides (or endotoxin) cause systemic inflammation, resulting in a substantial global health burden. The onset, progression, and resolution of the inflammatory response to endotoxin are usually tightly controlled to avoid chronic inflammation. Members of the NF-κB family of transcription factors are key drivers of inflammation that activate sets of genes in response to inflammatory signals. Such responses are typically short-lived and can be suppressed by proteins that act post-translationally, such as the SOCS (suppressor of cytokine signaling) family. Less is known about direct transcriptional regulation of these responses, however. Here, using a combination of in vitro approaches and in vivo animal models, we show that endotoxin treatment induced expression of the well-characterized transcriptional repressor Krüppel-like factor 3 (KLF3), which, in turn, directly repressed the expression of the NF-κB family member RELA/p65. We also observed that KLF3-deficient mice were hypersensitive to endotoxin and exhibited elevated levels of circulating Ly6C+ monocytes and macrophage-derived inflammatory cytokines. These findings reveal that KLF3 is a fundamental suppressor that operates as a feedback inhibitor of RELA/p65 and may be important in facilitating the resolution of inflammation.




fact

Rising drug prices drive US manufacturers’ revenues, analysis finds




fact

[ Politics ] Open Question : Should President Trump continue to have manufacturing sent to China???




fact

India’s research body partners with vaccine manufacturing company to develop indigenous vaccine for COVID-19 – China.org.cn

  1. India's research body partners with vaccine manufacturing company to develop indigenous vaccine for COVID-19  China.org.cn
  2. India to develop ‘fully indigenous’ Covid vaccine as ICMR partners with Bharat Biotech  ThePrint
  3. ICMR teams up with Bharat Biotech to develop Covid-19 vaccine  Times of India
  4. ICMR partners with Bharat Biotech to develop an indigenous coronavirus vaccine  Times Now
  5. ICMR joins with Hyderabad firm to develop COVID-19 vaccine  Northeast Now
  6. View Full coverage on Google News



  • IMC News Feed

fact

fACTOR: mentoring volunteers in Belgium

Relationships, mentoring, fun, practical work, spiritual growth and learning to love others are all part of OM Belgium's fACTOR programme.




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Sensex, Nifty plunge 5%, track global markets; key factors behind rout on Dalal Street

After opening nearly 3 per cent higher, RIL share price slipped 1.90 per cent in Mondays' trade. American private equity firm Silver Lake Partner announced an investment of Rs 5,655.75 crore in Reliance Jio.




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Sensex, Nifty snap two-day losing streak, financials outperform; key factors behind market rally

The rally in Sensex and Nifty was supported by buying in financial counters with HDFC Bank, HDFC, ICICI Bank and Bajaj Finance as top index contributors




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Bhel’s Make in India push to its idle plants; invites global firms to use its manufacturing facilities

With an eye at coronavirus as an opportunity, to put its idle plants to work, state-run Bhel has offered its manufacturing facilities to be used by global manufacturing firms looking to shift base.




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Resumption blues post COVID-19 lockdown: Factories grapple with shortage of workers, supply chain hurdles

Hobbled by a shortage of workers, companies are finding it hard to resume operations at an optimal scale and with migrants moving back home, it could be a while before factories hum with activity.




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Elon Musk threatens to PULL TESLA OUT of California as officials keep factory shut due to Covid-19

Billionaire Elon Musk has vowed to sue local authorities “immediately” after his Tesla electric car factory wasn’t allowed reopen due to Covid-19 restrictions, and has warned he’s considering pulling out of California altogether.
Read Full Article at RT.com




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That was quick! Tesla files LAWSUIT against California county for not allowing factory to reopen after Musk threatens pullout

Hours after Tesla CEO Elon Musk said that he would pull the car maker’s plant from the Golden State, the company sued Alameda county, accusing officials of “defying” state laws by refusing to allow the facility to reopen.
Read Full Article at RT.com