London : London Research Centre, 1991.

Dual first-order methods are essential techniques for large-scale constrained convex optimization. However, when recovering the primal solutions, we need $T(epsilon^{-2})$ iterations to achieve an $epsilon$-optimal primal solution when we apply an algorithm to the non-strongly convex dual problem with $T(epsilon^{-1})$ iterations to achieve an $epsilon$-optimal dual solution, where $T(x)$ can be $x$ or $sqrt{x}$. In this paper, we prove that the iteration complexity of the primal solutions and dual solutions have the same $Oleft(frac{1}{sqrt{epsilon}} ight)$ order of magnitude for the accelerated randomized dual coordinate ascent. When the dual function further satisfies the quadratic functional growth condition, by restarting the algorithm at any period, we establish the linear iteration complexity for both the primal solutions and dual solutions even if the condition number is unknown. When applied to the regularized empirical risk minimization problem, we prove the iteration complexity of $Oleft(nlog n+sqrt{frac{n}{epsilon}} ight)$ in both primal space and dual space, where $n$ is the number of samples. Our result takes out the $left(log frac{1}{epsilon} ight)$ factor compared with the methods based on smoothing/regularization or Catalyst reduction. As far as we know, this is the first time that the optimal $Oleft(sqrt{frac{n}{epsilon}} ight)$ iteration complexity in the primal space is established for the dual coordinate ascent based stochastic algorithms. We also establish the accelerated linear complexity for some problems with nonsmooth loss, e.g., the least absolute deviation and SVM.

Weiping Zhang, Jiangli Wang, Fang Qian, Yu Chen.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 1, 35--50.

Abstract:
Longitudinal zero-inflated count data are widely encountered in many fields, while modeling the correlation between measurements for the same subject is more challenge due to the lack of suitable multivariate joint distributions. This paper studies a novel mean-correlation modeling approach for longitudinal zero-inflated regression model, solving both problems of specifying joint distribution and parsimoniously modeling correlations with no constraint. The joint distribution of zero-inflated discrete longitudinal responses is modeled by a copula model whose correlation parameters are innovatively represented in hyper-spherical coordinates. To overcome the computational intractability in maximizing the full likelihood function of the model, we further propose a computationally efficient pairwise likelihood approach. We then propose separated mean and correlation regression models to model these key quantities, such modeling approach can also handle irregularly and possibly subject-specific times points. The resulting estimators are shown to be consistent and asymptotically normal. Data example and simulations support the effectiveness of the proposed approach.

John J. Dziak, Donna L. Coffman, Matthew Reimherr, Justin Petrovich, Runze Li, Saul Shiffman, Mariya P. Shiyko.

Source: Statistics Surveys, Volume 13, 150--180.

Abstract:
Researchers are sometimes interested in predicting a distal or external outcome (such as smoking cessation at follow-up) from the trajectory of an intensively recorded longitudinal variable (such as urge to smoke). This can be done in a semiparametric way via scalar-on-function regression. However, the resulting fitted coefficient regression function requires special care for correct interpretation, as it represents the joint relationship of time points to the outcome, rather than a marginal or cross-sectional relationship. We provide practical guidelines, based on experience with scientific applications, for helping practitioners interpret their results and illustrate these ideas using data from a smoking cessation study.

The R package mvord implements composite likelihood estimation in the class of multivariate ordinal regression models with a multivariate probit and a multivariate logit link. A flexible modeling framework for multiple ordinal measurements on the same subject is set up, which takes into consideration the dependence among the multiple observations by employing different error structures. Heterogeneity in the error structure across the subjects can be accounted for by the package, which allows for covariate dependent error structures. In addition, different regression coefficients and threshold parameters for each response are supported. If a reduction of the parameter space is desired, constraints on the threshold as well as on the regression coefficients can be specified by the user. The proposed multivariate framework is illustrated by means of a credit risk application.

This paper is devoted to the R package JSM which performs joint statistical modeling of survival and longitudinal data. In biomedical studies it has been increasingly common to collect both baseline and longitudinal covariates along with a possibly censored survival time. Instead of analyzing the survival and longitudinal outcomes separately, joint modeling approaches have attracted substantive attention in the recent literature and have been shown to correct biases from separate modeling approaches and enhance information. Most existing approaches adopt a linear mixed effects model for the longitudinal component and the Cox proportional hazards model for the survival component. We extend the Cox model to a more general class of transformation models for the survival process, where the baseline hazard function is completely unspecified leading to semiparametric survival models. We also offer a non-parametric multiplicative random effects model for the longitudinal process in JSM in addition to the linear mixed effects model. In this paper, we present the joint modeling framework that is implemented in JSM, as well as the standard error estimation methods, and illustrate the package with two real data examples: a liver cirrhosis data and a Mayo Clinic primary biliary cirrhosis data.

Rajarshi Guhaniyogi, Abel Rodriguez.

Source: Bayesian Analysis, Volume 15, Number 2, 477--503.

Abstract:
This article proposes a framework based on shared, time varying stochastic latent factor models for modeling relational data in which network and node-attributes co-evolve over time. Our proposed framework is flexible enough to handle both categorical and continuous attributes, allows us to estimate the dimension of the latent social space, and automatically yields Bayesian hypothesis tests for the association between network structure and nodal attributes. Additionally, the model is easy to compute and readily yields inference and prediction for missing link between nodes. We employ our model framework to study co-evolution of international relations between 22 countries and the country specific indicators over a period of 11 years.

Jong Hee Park, Yunkyu Sohn.

Source: Bayesian Analysis, Volume 15, Number 1, 133--157.

Abstract:
Dynamic modeling of longitudinal networks has been an increasingly important topic in applied research. While longitudinal network data commonly exhibit dramatic changes in its structures, existing methods have largely focused on modeling smooth topological changes over time. In this paper, we develop a hidden Markov network change-point model (HNC) that combines the multilinear tensor regression model (Hoff, 2011) with a hidden Markov model using Bayesian inference. We model changes in network structure as shifts in discrete states yielding particular sets of network generating parameters. Our simulation results demonstrate that the proposed method correctly detects the number, locations, and types of changes in latent node characteristics. We apply the proposed method to international military alliance networks to find structural changes in the coalition structure among nations.

Keynote speech by Mr Agustín Carstens, General Manager of the BIS, at the 55th SEACEN Governors' Conference and High-level Seminar on "Data and technology: embracing innovation", Singapore, 14 November 2019.

Currently in the works, the new monument will honor her contributions and legacy with a contemplative space

God uses Janet to reach people through one-on-one encounters at a bookshop in a closed country.

Press release "Basel Committee coordinates policy and supervisory response to Covid-19", 20 March 2020

Remarks by Mr Olli Rehn, Governor of the Bank of Finland, at the Reinventing Bretton Woods Committee Panel Discussion on "The world economy transformed: Reflections on policy responses and the future post pandemic monetary architecture", in the context of the virtual IMF Spring Meetings, Washington DC, 17 April 2020.

Cardinal Robert Sarah, head of the Vatican's liturgy office, claims he never signed a petition claiming the coronavirus is an over-hyped "pretext" to deprive the faithful of Mass.

God uses Janet to reach people through one-on-one encounters at a bookshop in a closed country.

CNA Staff, Apr 14, 2020 / 02:00 pm (CNA).- Cardinal George Pell has said culture wars and anti-Catholic sentiment could have played a part in the decision of Victoria police to pursue charges against him, even while they lacked supportive evidence of the allegations in his case.

Cardinal Pell described Victoria police as having “advertised for business” against him in an April 14 interview with Sky News Australia. Pell was asked about the decision by Victoria police to launch an open-ended investigation into him, despite having received no complaints of a crime.

The interview was Pell’s first televised appearance since his release last week after more than 400 days in prison. On the evidence of a single accuser, Pell was convicted in December 2018 of sexually assaulting two choirboys at the Melbourne Cathedral in 1996.

On April 7, the Australian High Court unanimously ruled that the evidence presented during the trial would not have allowed the jury to avoid reasonable doubt and ordered Pell’s acquittal and release.

On the day of his release, Pell told CNA that “The only basis for long term healing is truth and the only basis for justice is truth, because justice means truth for all.”

Pell spoke with Sky News’ Andrew Bolt about the decision by local police to bring 28 allegations of sexual abuse against him, only to see 27 of them dropped before reaching court. The remaining allegation resulted in Pell’s conviction by a Victoria jury and eventual acquittal by the High Court.

Asked directly if he thought police were “out to get” him, Pell said he did not know.

“I don’t know how you explain it, but it is certainly extraordinary,” Pell said.

Asked if he thought there was an anti-Catholic bias at work in the decision of police to charge him and by judges at the Victoria Court of Appeal to sustain his conviction, despite the evidence which eventually led to his exoneration, Pell said it was a possibility.

“I’ve seen too many people [make the leap] from possible to probable to fact. Certainly, people do not like Christians who teach Christianity, especially on life and family and issues like that.”

“The culture wars are real,” Pell said. “There is a systematic attempt to remove the Judeo-Christian legal foundations [on for example] marriage, life, gender, sex.”

“Unfortunately, there’s less rational discussion and more playing the man, more abuse and intimidation, and that’s not good for a democracy.”

During the interview, the cardinal was also asked if he believed that there was any connection between his work to reform the Vatican finances during his time as Prefect for the Economy and the emergence of charges against him in Victoria.

“Most of the senior people in Rome who are in any way sympathetic to financial reform believe that they are [connected]. But I have seen too much from people, as I said, going to possibility to probability to fact – I don’t have any evidence of that.”

“But one of my fears was that what we had done [to reform the Vatican finances] would remain hidden for ten years or so, and they’d would be revealed and the baddies would say ‘Well, Pell and Casey [Pell’s chief advisor] were in charge then, they turned a blind eye and did nothing to it.’”

“Thanks be to God all that’s gone, because there was a flurry of articles just before Christmas exposing all sorts of things like a disastrous purchase – actually a couple of them – in London, and it was very clearly demonstrated that we tenaciously opposed those things.”

“What we were pushing and saying has been massively vindicated,” Pell said. “Now you can see why they sacked the auditor [Libero Milone], why they got rid of the external auditors.”

Asked how high up in the curial hierarchy financial corruption goes, Pell said “Who knows? It’s a little bit like [anti-Catholicism] in Victoria, you’re not quite sure where the vein runs, how thick and broad it is, and how high it goes.”

But the cardinal also made clear that, in financial reforming efforts, Pope Francis had “absolutely” supported him and that “at the feet of the pope we’ve got Cardinal [Pietro] Parolin, he’s certainly not corrupt. Just how high up [the corruption goes] is an interesting hypothesis.”

Pell said that despite the difficulties he faced in prison, where he was held in solitary confinement for much of the time for his own safety, he bore no anger towards his accuser.

“I’ve got no anger, no hostility towards my complainant, I never have,” said Pell.

“I am called to forgive what happened to me that might have been a little unjust, and there is this heroic Christian call to forgiveness in the most appalling circumstances.”

But, Pell said, he had no hesitation in condemning the terrible scandal of sexual abuse in the Church.

“I totally condemn those sorts of activities [of abuse] and the damage that it has done to people – and I have seen the damage that it has done to people.”

“One of the things that grieves me is the suggestion that I’m anti-victim or not sufficiently sympathetic. I devoted a lot of time and energy to trying to get [victims] justice, and to get them help and compensation.”

Pell noted that as archbishop in the 1990s he set up the Melbourne Response to deal with sexual abuse in the Church and bringing about justice and compensation for victims.

“I worked hard,” Pell said, “when it wasn’t easy or fashionable, to get something in place – not run by clerics – that would give some protection and redress to these people, and I have worked consistently at that since at least the middle 90s.”

The cardinal said he had kept the same routine while in prison that, as a bishop, he had often urged on priests who found themselves “in a bit of trouble;” getting up early and at a set time, praying, exercising, and eating well.

“If you can’t pray when you are in trouble, your faith is very weak indeed.”

Asked if he had ever asked God, in the words of Christ on the cross, “why have you forsaken me?” Pell responded “No.”

“But I have said ‘My God, my God, what are you up to?’”

“One of the strangest teachings about Christianity – and the most useful – is that you can offer up your suffering,” Pell said. “Suffering is not just a brute fact. A Christian can offer that up to the Good God.”

CNA Staff, May 7, 2020 / 11:00 am (CNA).- Cardinal George Pell has expressed his “surprise” at newly released findings of an Australian investigation, which concluded that the cardinal was aware of sexual abuse by clerics in the 1970s and 80s, and failed to act.

In 2017, Australia’s Royal Commission released a report on sexual abuse of minors in the country, the result of a five-year enquiry into the behavior and responsibility of institutions including the Church. Sections of the report relating to Cardinal Pell were redacted until the conclusion of criminal legal proceedings against the cardinal. 

The redacted portions were released May 6.

In the newly available material, the commission found that Pell knew about the abusive activities of two priests during his own years as a priest, and that he failed to act to stop them. 

On Thursday, Pell said through a spokesperson that the commission’s conclusions about him were “not supported by evidence.”

Pell gave evidence to the commission in 2016 via video link from Rome. During his testimony, he denied failing to act against known sexual abusers in the clergy. Pell specifically denied that while he was a priest in Ballarat in the 1970s and 80s, he had any awareness of the actions of then-Father Gerald Ridsdale, a serial abuser from the same diocese.

The Royal Commission concluded that, as a member of Bishop Ronald Mulkearns’ college of priest consulters in the diocese, Pell would have been made aware of allegations of abuse against Ridsdale during discussions about the priest’s transfers between assignments in 1977 and 1982.

But Pell told the commission that he and the other consulters had been deceived by Mulkearns and were unaware of Ridsdale’s crimes until years later.

“The Consultors who gave evidence on the meetings in 1977 and 1982 either said they did not learn of Ridsdale’s offending against children until much later or they had no recollection of what was discussed. None said they were made aware of Ridsdale’s offending at these meetings,” Pell said in a statement released through a spokesperson late Wednesday evening.

In a 2017 statement, Pell said “I would never have condoned or participated in a decision to transfer Ridsdale in the knowledge that he had abused children, and I did not do so.” 

The commission rejected Pell’s testimony, and found that it “ought to have been obvious” why Ridsdale was being transferred from one assignment to another.

“We are satisfied Bishop Mulkearns gave reasons for it being necessary to move Ridsdale. We are satisfied that he referred to homosexuality at the meeting, in the context of giving reasons for Ridsdale’s move,” the report found. “However, we are not satisfied that Bishop Mulkearns left the explanation there, as Cardinal Pell said there would have been a discussion."

“We do not accept that Bishop Mulkearns lied to his consultors.”

The commission did not delineate specific proofs for its conclusion.

The commission also said that Pell would have known about allegations of abuse made against Fr. Peter Searson, who was active as a Melbourne priest during Pell’s time as an auxiliary bishop in the Melbourne archdiocese.

In 1989, Pell held a meeting with representatives from the parish and school in Doveton, where Searson was assigned. During that meeting a number of complaints were made against Searson but, according to Pell, sexual misconduct with children was not raised, and Searson’s removal was not requested.

Following Pell’s installation as Archbishop of Melbourne in 1996, Pell placed Searson on administrative leave and removed him from parish ministry in 1997. Searson died in 2009 and was never charged by police.

A spokesman for Victoria Police, which brought charges against Pell leading to his imprisonment for more than a year before the High Court freed him last month, told the Guardian that the newly released sections of the report would be studied and police would “undertake an assessment of those findings.”

“At this time it would not be appropriate to comment further about any possible action,” The spokesman said.

Current Archbishop of Melbourne Peter Comensoli released his own statement in response to the new material from the commission, in which he repeated his previous apologies “for the failure of the Catholic Archdiocese of Melbourne to responsibly care for and protect our young people and vulnerable adults.”

“Child safety and care is not a project with an end date”, Comensoli said, but a project that “requires life-long vigilance.”

In December 2018, Pell was convicted of five counts of sexual abuse, but was acquitted by the Australian High Court last monthl. Following that decision, the redacted portions of the commission’s findings were released.

Hope of Israel winter team spreads good news in a variety of ways.

CNA Staff, May 8, 2020 / 10:25 am (CNA).- Archbishop Carlo Maria Viganò has accused a Vatican cardinal of causing him “serious harm” in a bitter war of words over a controversial open letter regarding the coronavirus crisis.

In a statement published May 8, the archbishop criticized Cardinal Robert Sarah’s decision to distance himself from the letter, titled “Appeal for the Church and the World,” which argues that the coronavirus pandemic has been exploited in order to create a one-world government.

The statement details Vigano’s account of his interactions with Sarah beginning May 4. Viganò claims that on the evening of May 7, the prefect of the Vatican's Congregation for Divine Worship and Sacraments asked him to remove him from the list of signatories to the letter, which had by that time already been published.

“With surprise and deep regret,” he wrote, “I then learned that His Eminence had used his Twitter account, without giving me any notice, to make statements that cause serious harm to the truth and to my person.”

Viganò was referring to a series of three May 7 tweets from Sarah, which said: “A Cardinal Prefect, member of the Roman Curia has to observe a certain restriction  on political matters. He shouldn't sign petitions in such aereas [sic].”

“Therefore this morning I explicitely [sic] asked the authors of the petition titled ‘For the Church and for the world’ not to mention my name.”

“From a personal point of view, I may share some questions or preoccupations raised regarding restrictions on fundamental freedom but I didn't sign that petition,” Sarah added.

Viganò’s statement continued: “I am very sorry that this matter, which is due to human weakness, and for which I bear no resentment towards the person who caused it, has distracted our attention from what must seriously concern us at this dramatic moment.”

After Viganò issued his rebuke, Sarah tweeted May 8: “I will not speak to this petition, which today seems to occupy a lot of people. I leave to their conscience those who want to exploit it in one way or another. I decided not to sign this text. I fully accept my choice.”

In his statement, Viganò said he had chosen to publicize his private conversations with Sarah because he had a duty to tell the truth, and “also for the sake of fraternal correction.”

Vigano said Sarah had initially told him: “Yes, I agree to put my name to it, because this is a fight we must engage in together, not only for the Catholic Church but for all mankind.”

He confirmed that Sarah’s signature has now been removed from the open letter.

Vigano, a former papal nuncio made headlines in August 2018, for a letter that alleged Vatican officials had ignored warnings about the sexual abuse of disgraced former cardinal Theodore McCarrick. Since that time, Vigano has released numerous letters expressing his viewpoints on matters in the Church, which include criticisms of Pope Francis and other curial officials.

The appeal argued that as a result of the pandemic centuries of Christian civilization could be “erased under the pretext of a virus” and an “odious technological tyranny” established in its place.

It said: “We have reason to believe, on the basis of official data on the incidence of the epidemic as related to the number of deaths, that there are powers interested in creating panic among the world’s population with the sole aim of permanently imposing unacceptable forms of restriction on freedoms, of controlling people and of tracking their movements. The imposition of these illiberal measures is a disturbing prelude to the realization of a World Government beyond all control.”

Several bishops and cardinals are alleged to have signed the letter. Bishop Joseph Strickland of Tyler, Texas told CNA May 7 that he had signed it.

A press release on the appeal’s website May 8 claimed that Robert Kennedy Jr, son of the slain US. Presidential candidate Sen. Robert Kennedy, had signed the letter.

To date, nearly 4 million people have tested positive for the coronavirus, and at least 272,000 have died.

CNA Staff, May 7, 2020 / 03:45 pm (CNA).- Hours after the publication of a controversial open letter regarding the coronavirus pandemic, the prefect of the Church’s dicastery for liturgy and sacraments, listed among the signers of the letter, said he did not sign it.

The letter, titled “Appeal for the Church and the World,” says the coronavirus pandemic has been exaggerated to foster widespread social panic and undercut freedom, as a preparation for the establishment of a one-world government.

Cardinal Robert Sarah, prefect of the Vatican's Congregation for Divine Worship and Sacraments, tweeted: “I share on a personal basis some of the questions or concerns raised with regard to restrictions on fundamental freedoms, but I have not signed this petition.”

“A cardinal prefect of the Roman Curia must observe a certain reserve in political matters, Sarah wrote in another tweet, “so I explicitly asked this morning the authors of the petition titled ‘for the Church and for the world’ not to mention me.”

Sarah was listed as a signatory of the letter when it was published May 7 by the National Catholic Register, LifeSiteNews, and other websites. Sarah's denial raises questions about the legitimacy of other reported signatories to the letter.

Jeanette DeMelo, editor of the National Catholic Register, told CNA that the principal author of the letter is Archbishop Carlo Vigano, a former papal emissary to the United States.

Vigano made headlines for an August 2018 letter that alleged Vatican officials had ignored warnings about the sexual abuse of disgraced former cardinal Theodore McCarrick. Since that time, Vigano has released numerous letters expressing his viewpoints on matters in the Church, which include criticisms of Pope Francis and other curial officials.

DeMelo said that Vigano had vouched for the authenticity of Sarah's signature.

“The Register contacted Archbishop Vigano, the principal author, and asked him specifically about the authenticity of the signature of Cardinal Sarah and he said ‘I can confirm 100% that Cardinal Sarah signed it.,” DeMelo told CNA.

The letter laments the social distancing and stay-at-home orders issued to slow the spread of the coronavirus pandemic, suggesting they are contrived mechanisms of social control, with a nefarious purpose.

“We have reason to believe, on the basis of official data on the incidence of the epidemic as related to the number of deaths, that there are powers interested in creating panic among the world’s population with the sole aim of permanently imposing unacceptable forms of restriction on freedoms, of controlling people and of tracking their movements,” the letter said.

“The imposition of these illiberal measures is a disturbing prelude to the realization of a world government beyond all control,” it added. (bold original)

Among the letter’s reported signatories are four cardinals: Sarah, who has now indicated he is not a signatory; Cardinal Gerhard Muller, former prefect of the Congregation for the Doctrine of the Faith, Cardinal Joseph Zen, emeritus bishop of Hong Kong, and Cardinal Janis Pujats, emeritus archbishop of Riga, Latvia.

Two U.S. bishops are also alleged signatories: Bishop Rene Gracida, emeritus bishop of Corpus Christi, and Bishop Joseph Strickland, the Bishop of Tyler, Texas. 

Strickland told CNA by email May 7 that he “did sign off on this letter.”

Along with several other bishops, the well-known auxiliary bishop of Astana, Kazakhstan, Bishop Athanasius Schneider, is listed as a signer of the letter.

Another reported signatory is Fr. Curzio Nitoglia, a priest of the Society of St. Pius X, a traditionalist group in “irregular communion” with the Church. Nitoglia is the author of “The Magisterium of Vatican II,” a 1994 article that claims that “the church of Vatican II is therefore not the Apostolic and Roman Catholic Church instituted by our Lord Jesus Christ.”

The May 7 letter argued that the coronavirus pandemic has been sensationalized and exploited, to impede civil rights and exact government control over individuals and families.

The letter said that “the facts have shown that, under the pretext of the Covid-19 epidemic, the inalienable rights of citizens have in many cases been violated and their fundamental freedoms, including the exercise of freedom of worship, expression and movement, have been disproportionately and unjustifiably restricted.”

“Many authoritative voices in the world of science and medicine confirm that the media’s alarmism about Covid-19 appears to be absolutely unjustified.”

Nearly 4 million people worldwide have tested positive for the coronavirus, and at least 270,000 have died. In some countries, death rates in the months of the coronavirus pandemic have far exceeded death rates over the same months in previous years, suggesting to some demographers and epidemiologists that coronavirus deaths have been dramatically undercounted.

The pandemic, and the social distancing and stay-at-home orders issued to slow its spread, have become a source of considerable controversy in recent weeks. In the U.S., protests in several state capitals have gathered demonstrators in close proximity to one another, a move public health experts say could lead to new outbreaks of the disease.

The letter said that the economic crisis occasioned by the global pandemic “encourages interference by foreign powers and has serious social and political repercussions. Those with governmental responsibility must stop these forms of social engineering, by taking measures to protect their citizens whom they represent, and in whose interests they have a serious obligation to act.”

“The criminalization of personal and social relationships must likewise be judged as an unacceptable part of the plan of those who advocate isolating individuals in order to better manipulate and control them,” the authors added.

No cure or therapeutic treatment has yet been identified for the virus. In early weeks of the pandemic, President Donald Trump hypothesized that hydroxychloroquine, an inexpensive anti-malarial medication, could help treat the disease. U.S. researchers have largely moved away from the medication, especially after a study by the Veterans’ Administration found that administering the drug leads to higher death rates among patients receiving it.

Some, including television hosts Laura Ingraham and Sean Hannity have alleged that the study is inaccurate. Some protestors have suggested the VA study was intended to discredit Trump or profit vaccine manufacturers.

In an apparent reference to the hydroxychloroquine controversy, the letter said that: “Every effort must be made to ensure that shady business interests do not influence the choices made by government leaders and international bodies. It is unreasonable to penalize those remedies that have proved to be effective, and are often inexpensive, just because one wishes to give priority to treatments or vaccines that are not as good, but which guarantee pharmaceutical companies far greater profits, and exacerbate public health expenditures.” 

“Let us also remember, as Pastors, that for Catholics it is morally unacceptable to develop or use vaccines derived from material from aborted fetuses,” the letter added.

The U.S. bishops conference has also said vaccine development should avoid unethical links to abortion.

The letter argues that governments do not have the right to ban or restrict public worship or other kinds of ministry, and asks that any such restrictions be rescinded.

On the sacraments, which have been subject both to voluntary restrictions and public health orders in some states, the letter noted that “the Church firmly asserts her autonomy to govern, worship, and teach.”

“The State has no right to interfere, for any reason whatsoever, in the sovereignty of the Church. Ecclesiastical authorities have never refused to collaborate with the State, but such collaboration does not authorize civil authorities to impose any sort of ban or restriction on public worship or the exercise of priestly ministry. The rights of God and of the faithful are the supreme law of the Church, which she neither intends to, nor can, abdicate. We ask that restrictions on the celebration of public ceremonies be removed.”

While restrictions on public worship have been met with public criticism in many places, the objections have been most pronounced in Italy.

After Italy’s prime minister announced in late April new health measures that would continue prohibiting religious gatherings, the Italian bishops released a statement denouncing the decision, which the bishops criticized as “arbitrary.” Two days later, Pope Francis seemed to signal his own view, praying while celebrating Mass that Christians would respond to the lifting of lockdown restrictions with “prudence and obedience.”

Along with cardinals, bishops, and priests, the letter’s signatories also included some academics, journalists, and scientists. Included among them are Vatican journalists Marco Tosatti and Robert Moynihan, Lifesitenews editor John-Henry Westen, Stephen Mosher, president of the Virginia-based Population Research Institute, and the leaders of pro-life groups in Texas and Ohio.

The letter’s signatories encouraged Catholics, and “all men and women of good will” to “assess the current situation in a way consistent with the teaching of the Gospel. This means taking a stand: either with Christ or against Christ.” (bold original)
 
“Let us not allow centuries of Christian civilization to be erased under the pretext of a virus, and an odious technological tyranny to be established, in which nameless and faceless people can decide the fate of the world by confining us to a virtual reality. If this is the plan to which the powers of this earth intend to make us yield, know that Jesus Christ, King and Lord of History, has promised that ‘the gates of Hell shall not prevail’ (Mt 16:18).”

The Holy See has not yet commented on the letter.
 

This story has been updated since its original publication. It is developing and will continue to be updated.

CNA Staff, May 8, 2020 / 10:25 am (CNA).- Archbishop Carlo Maria Viganò has accused a Vatican cardinal of causing him “serious harm” in a bitter war of words over a controversial open letter regarding the coronavirus crisis.

In a statement published May 8, the archbishop criticized Cardinal Robert Sarah’s decision to distance himself from the letter, titled “Appeal for the Church and the World,” which argues that the coronavirus pandemic has been exploited in order to create a one-world government.

The statement details Vigano’s account of his interactions with Sarah beginning May 4. Viganò claims that on the evening of May 7, the prefect of the Vatican's Congregation for Divine Worship and Sacraments asked him to remove him from the list of signatories to the letter, which had by that time already been published.

“With surprise and deep regret,” he wrote, “I then learned that His Eminence had used his Twitter account, without giving me any notice, to make statements that cause serious harm to the truth and to my person.”

Viganò was referring to a series of three May 7 tweets from Sarah, which said: “A Cardinal Prefect, member of the Roman Curia has to observe a certain restriction  on political matters. He shouldn't sign petitions in such aereas [sic].”

“Therefore this morning I explicitely [sic] asked the authors of the petition titled ‘For the Church and for the world’ not to mention my name.”

“From a personal point of view, I may share some questions or preoccupations raised regarding restrictions on fundamental freedom but I didn't sign that petition,” Sarah added.

Viganò’s statement continued: “I am very sorry that this matter, which is due to human weakness, and for which I bear no resentment towards the person who caused it, has distracted our attention from what must seriously concern us at this dramatic moment.”

After Viganò issued his rebuke, Sarah tweeted May 8: “I will not speak to this petition, which today seems to occupy a lot of people. I leave to their conscience those who want to exploit it in one way or another. I decided not to sign this text. I fully accept my choice.”

In his statement, Viganò said he had chosen to publicize his private conversations with Sarah because he had a duty to tell the truth, and “also for the sake of fraternal correction.”

Vigano said Sarah had initially told him: “Yes, I agree to put my name to it, because this is a fight we must engage in together, not only for the Catholic Church but for all mankind.”

He confirmed that Sarah’s signature has now been removed from the open letter.

Vigano, a former papal nuncio made headlines in August 2018, for a letter that alleged Vatican officials had ignored warnings about the sexual abuse of disgraced former cardinal Theodore McCarrick. Since that time, Vigano has released numerous letters expressing his viewpoints on matters in the Church, which include criticisms of Pope Francis and other curial officials.

The appeal argued that as a result of the pandemic centuries of Christian civilization could be “erased under the pretext of a virus” and an “odious technological tyranny” established in its place.

It said: “We have reason to believe, on the basis of official data on the incidence of the epidemic as related to the number of deaths, that there are powers interested in creating panic among the world’s population with the sole aim of permanently imposing unacceptable forms of restriction on freedoms, of controlling people and of tracking their movements. The imposition of these illiberal measures is a disturbing prelude to the realization of a World Government beyond all control.”

Several bishops and cardinals are alleged to have signed the letter. Bishop Joseph Strickland of Tyler, Texas told CNA May 7 that he had signed it.

A press release on the appeal’s website May 8 claimed that Robert Kennedy Jr, son of the slain US. Presidential candidate Sen. Robert Kennedy, had signed the letter.

To date, nearly 4 million people have tested positive for the coronavirus, and at least 272,000 have died.

Several correlational studies documented that participants who would be classified as "pathological" video gamers demonstrate a pattern of correlations with other variables that are comorbid (eg, depression) or occur with (eg, poorer grades and increased hostility) other addictions.

Following a large sample across 2 years, this study provides needed data on risk factors for becoming a pathological gamer, how long pathological gaming lasts, outcomes, and whether it is a primary problem or is a symptom of comorbid problems. (Read the full article)

Adolescence is a time of risk taking, with poor inner-city youth at greater risk than the general population for drug use, school failure, adjudication, and teen parenthood. Little is known regarding these youths’ perceptions and intentions in early childhood.

Poor inner-city children were surprisingly idealistic regarding their future. Despite this, by late adolescence most experienced 1 or more trajectory-altering events. Early childhood experiences, exposure to violence and poor home environment, were factors most strongly associated with these outcomes. (Read the full article)

Research has highlighted an important relationship between motor coordination and emotional functioning in children and adolescents. Few studies have provided support for this idea; research is therefore needed to further understand the relationship between the motor and emotional domains.

The results suggest that the relationship between motor coordination and emotional functioning (anxious and depressive symptoms) in an adolescent sample may be understood in terms of a mechanism whereby motor coordination has an indirect impact on emotional functioning via self-perceptions. (Read the full article)

Cross-sectional studies have shown an increased risk of mental health difficulties in children with developmental coordination disorder. However, there has been limited longitudinal research in this area controlling for confounding factors and assessing the role of potential mediators.

Children with "probable" developmental coordination disorder at 7 years had a significantly increased risk mental health difficulties at 10 years. Protective factors for self-reported depression included high IQ, high self-esteem, good social communication skills, and the absence of bullying. (Read the full article)

Maternal obesity is an increasingly important public health concern and may adversely affect central nervous system development in offspring. However, few studies have explored the relationship between maternal prepregnancy BMI and neurodevelopmental outcomes in children, with conflicting results.

Using data from a large and contemporary UK birth cohort, we found that maternal prepregnancy BMI is negatively associated with children’s cognitive performance. The relationship appears to become stronger as children get older, although the overall effect size is modest. (Read the full article)

Although a number of cross-sectional studies have documented associations between teen dating violence victimization and adverse health outcomes, including sexual risk behaviors, suicidality, substance use, and depression, longitudinal work examining the relationship between victimization and outcomes is limited.

This study is the first to demonstrate the longitudinal associations between teen dating violence victimization and multiple young adult health outcomes in a nationally representative sample. Findings emphasize the need for screening and intervention for both male and female victims. (Read the full article)

Care coordination has been proposed as a key mechanism for increasing quality and reducing costs of care. Little is known about the degree to which disparities exist in care coordination or whether having high-quality primary care attenuates disparities.

A considerable proportion of parents reported unmet care coordination needs for their children, especially parents of children with special health care needs. Black and Latino children also may have more unmet needs because they received family-centered care less often. (Read the full article)

Research indicates that adolescents who perceive their school to have a positive socioeducational environment are at reduced risk of developing depressive symptoms. However, there is limited evidence that school environments can influence adolescent emotional health independently from individual perceptions.

This multilevel longitudinal study shows that better school socioeducational environments, as assessed at the school level, reduce the prospective risk of depressive symptoms in adolescents. This association is shown to be independent from confounders and stronger in girls than boys. (Read the full article)

Adolescents are likely to smoke if their parent(s) smoke. Little research uses prospective longitudinal data from parents and children to more confidently document these intergenerational associations, alongside potential confounders (parental education) and mediators (school achievement, mental health, older sibling smoking).

Analyses of long-term multigenerational data show how diverse parental smoking trajectories influence child smoking, controlling for measured confounders. The risk of smoking is especially high among children residing with a persistent heavy smoking parent and an older sibling who smokes. (Read the full article)

Cross-sectional estimates suggest that one-third of children are enrolled in Medicaid or other public insurance programs. The percentage of children enrolled in Medicaid at any point during childhood, and which children use Medicaid as a longer-term insurance source, is unknown.

Over a 5-year period, 41% of children were enrolled in Medicaid at some point. Of those children, 51.5% were enrolled during all 5 years. Children with sociodemographic risk factors are more often enrolled for longer periods of childhood. (Read the full article)

Several studies have documented earlier onset of pubertal maturation in girls, with several potential factors attributed to the earlier onset.

This study demonstrates earlier maturation in white non-Hispanic girls, with greater BMI linked as a major factor. The entire distribution of pubertal timing has shifted to a younger age, suggesting redefinition of ages for both early and late maturation. (Read the full article)

To prevent asthma exacerbations, asthma guidelines recommend ongoing monitoring of patients’ asthma symptoms to promote timely adjustments of therapy to achieve and maintain optimal control. Existing tools, validated for ongoing monitoring, have significant limitations in children.

Our study established longitudinal validation of the Asthma Symptom Tracker, a novel tool designed for use by children or their parents to facilitate ongoing monitoring of patients’ asthma symptoms and proactive medical decision-making to prevent acute exacerbations. (Read the full article)

Childhood obesity poses a serious threat to human health. Obesity is caused by genetic and environmental factors and linked to type 2 diabetes and cardiovascular disease. Pediatric obesity cohorts aim at understanding early events in the pathophysiology of obesity-related complications.

Cohort subjects are examined at consecutive visits, including measurements of glucose tolerance and hormones regulating nutrient handling (enhanced glucose tolerance tests) and body composition (MRI and bioimpedance). Mechanisms causing obese children to progress to type 2 diabetes are delineated. (Read the full article)

Although care coordination has been associated with lower health care costs and improved outcomes for vulnerable children, little is known about the extent of need and factors associated with unmet need for care coordination among children with mental health conditions.

Children with mental health conditions have substantial need and unmet need for care coordination. Unmet need is more likely for families with children with anxiety disorder and less likely for those who report social support and family-centered care. (Read the full article)

There is growing understanding of the detrimental effect of paternal depression on children. The transition to fatherhood is a unique time for men. Identifying which fathers are at-risk and when will inform effective methods to help men and their families.

Nonresident fathers have the highest depression symptom scores, peaking before entering fatherhood. Although resident fathers’ scores decrease preceding entry into fatherhood, there is a significant increase from 0 to 5 years of their child’s life when key parent–infant attachment occurs. (Read the full article)

Parents of children with special health care needs and low-income children report more unmet specialty care needs. Care coordination is associated with increased and decreased referrals to specialty care, but whether care coordination is related to unmet needs is unknown.

Among children with special health care needs, care coordination is associated with lower odds of unmet specialty care needs regardless of whether care coordination was received within a medical home. This association was independent of household income. (Read the full article)

After neonatal extracorporeal membrane oxygenation treatment, children are at risk for neurodevelopmental problems including delayed motor function. So far this has only been studied cross-sectionally until age 7 years.

We describe, in a nationwide evaluation, the longitudinal course of motor function development after neonatal extracorporeal membrane oxygenation with persisting problems up to 12 years. At risk are children with congenital diaphragmatic hernia and those with chronic lung disease. (Read the full article)

To date, studies of adaptive behavior in fragile X syndrome have focused on particular age points, either longitudinally or cross-sectionally across a broad age spectrum. Studies have shown variable patterns in adaptive behavior among people with fragile X syndrome.

This study fills a critical gap in knowledge about the profile of adaptive behavior across childhood, adolescence, and young adulthood in fragile X syndrome. This study is the first to incorporate longitudinal data from an age-matched typically developing group. (Read the full article)

Stimulant medications are indicated for treatment of childhood attention-deficit/hyperactivity disorder (ADHD), but there is concern that stimulants may negatively affect growth. However, no longitudinal, population-based studies have examined height into adulthood for childhood ADHD cases.

This longitudinal, population-based study shows that neither childhood ADHD itself nor treatment with stimulants is associated with significant deficits in height into adulthood. (Read the full article)

Being bullied can lead to adverse physical and mental health outcomes. Individuals who experience a sudden traumatic event often have short-term disturbances in their sleep patterns. Ongoing trauma may result in extended periods of sleep disruption.

Being bullied in elementary school predicts parasomnias, such as nightmares and night terrors, years later. General practitioners, pediatricians, parents, and teachers may consider parasomnias as potential signs of being bullied. (Read the full article)

Cross-sectional research indicates that teen sexting is common, may be associated with other adolescent behaviors such as substance use, does not appear to be a marker of mental well being, and is probably an indicator of actual sexual behaviors.

Although mounting evidence links teen sexting to sexual behavior, little is known about the temporal sequencing of these 2 behaviors. Knowing which comes first will aid tween- and teen-focused health care providers in their interaction with patients and patients’ parents. (Read the full article)

Obesity among youth can have immediate health effects as well as longer-term consequences during adulthood. Overweight/obese children and adolescents are much more likely than normal-weight children to become overweight/obese adults.

This large, multisite longitudinal study examines patterns of exit from and entry into obesity between childhood and adolescence. Socioeconomic factors, body image, television habits, and parental obesity were important predictors of whether children remained obese or became obese. (Read the full article)

Early-life lower respiratory illnesses, including pneumonia, are associated with increased prevalence of asthma and diminished lung function in children. Whether early-life pneumonia is associated with subsequent impaired lung function and asthma in adults is not yet clear.

This is the first article providing strong data for an association between early-life pneumonia in an outpatient setting and airflow limitation and asthma into adulthood, supporting the hypothesis of the early-life origins of chronic obstructive pulmonary disease. (Read the full article)

Pediatric palliative care (PPC) improves the quality of life for children with life-limiting illness and their families. The association between PPC and health care costs is unclear and has not been studied over time.

PPC recipients were more medically complex. Receipt of PPC was associated with lower costs when death was near but with greater costs among survivors. When controlling for medical complexity, costs did not differ significantly according to receipt of PPC. (Read the full article)

Care coordination is a central part of the medical home model. Little is known about how care coordination is implemented in pediatrics and how it changes over time in primary care practices successfully adopting medical home principles.

In high-performing medical homes, care coordination evolved toward designing and carrying out routine activities and policies that aimed to forestall disruptions in care delivery. Investing in medical home teams, engaging electronic medical record systems, and improving workflow supported these changes. (Read the full article)

War-affected youth often suffer from multiple co-occurring mental health problems. The relationship of these conditions to later mental health has yet to be thoroughly investigated. There is a need to explore potential targets for mental health interventions.

After controlling for preexisting conditions and contemporary confounders, internalizing (depression and anxiety) remained the major predictor of future mental health symptoms (internalizing symptoms, prosocial attitudes/behaviors, and posttraumatic stress symptoms). Interventions targeting internalizing in war-affected youth hold promise. (Read the full article)

Brain infections with Cryptococcus neoformans are associated with significant morbidity and mortality. Cryptococcosis typically presents as meningoencephalitis or fungal mass lesions called cryptococcomas. Despite frequent in vitro discoveries of promising novel antifungals, the clinical need for drugs that can more efficiently treat these brain infections remains. A crucial step in drug development is the evaluation of in vivo drug efficacy in animal models. This mainly relies on survival studies or post-mortem analyses in large groups of animals, but these techniques only provide information on specific organs of interest at predefined time points. In this proof-of-concept study, we validated the use of non-invasive preclinical imaging to obtain longitudinal information on the therapeutic efficacy of amphotericin B or fluconazole monotherapy in meningoencephalitis and cryptococcoma mouse models. Bioluminescence imaging (BLI) enabled the rapid in vitro and in vivo evaluation of drug efficacy while complementary high-resolution anatomical information obtained by magnetic resonance imaging (MRI) of the brain allowed a precise assessment of the extent of infection and lesion growth rates. We demonstrated a good correlation between both imaging readouts and the fungal burden in various organs. Moreover, we identified potential pitfalls associated with the interpretation of therapeutic efficacy based solely on post-mortem studies, demonstrating the added value of this non-invasive dual imaging approach compared to standard mortality curves or fungal load endpoints. This novel preclinical imaging platform provides insights in the dynamic aspects of the therapeutic response and facilitates a more efficient and accurate translation of promising antifungal compounds from bench to bedside.

God uses Janet to reach people through one-on-one encounters at a bookshop in a closed country.

God uses Janet to reach people through one-on-one encounters at a bookshop in a closed country.