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Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial




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Exposure to direct-to-consumer advertising is associated with overestimation of benefits regarding ultrahypofractionated radiation therapy for prostate cancer




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Thermophysical properties of a Si<sub>50</sub>Ge<sub>50</sub> melt measured on board the International Space Station

npj Microgravity, Published online: 25 March 2020; doi:10.1038/s41526-020-0100-5

Thermophysical properties of a Si50Ge50 melt measured on board the International Space Station




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Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity




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Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy




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Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells




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Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy




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Δ<sup>9</sup>-Tetrahydrocannabinol (THC) impairs visual working memory performance: a randomized crossover trial




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Author Correction: Insights into parathyroid hormone secretion




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Nonoperative treatment of traumatic spinal injuries in Tanzania: who is not undergoing surgery and why?




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Functional neural correlates of psychopathy: a meta-analysis of MRI data




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Genomic characterization of patients with polycythemia vera developing resistance to hydroxyurea




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Why Authoritarianism is Bad for Science, But Bigotry is Even Worse

There have been many protests against the Citizenship Amendment Bill (now Act), and there will be many more. This piece of legislation strikes at the heart of the Constitution, seeking to make India another country altogether. It is thus that so many people from so many different walks of life have raised their voices against [...]




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Why There is No Team Modi – Because There Can Only Be a Brand Modi, The Telegraph

In December 2018, I was having lunch with an entrepreneur-friend who works closely with the Central Government. The BJP had just lost state elections in Madhya Pradesh, Rajasthan and Chattisgarh, putting three Chief Ministers out of office and out of work. I suggested to the entrepreneur that when the Prime Minister won re-election the following [...]




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Evaluation of an AI system for the detection of diabetic retinopathy from images captured with a handheld portable fundus camera: the MAILOR AI study




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Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




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Promoting healthy lifestyle in Chinese college students: evaluation of a social media-based intervention applying the RE-AIM framework




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Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




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Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




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Elevated sorbitol underlies a heritable neuropathy




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Biallelic mutations in <i>SORD</i> cause a common and potentially treatable hereditary neuropathy with implications for diabetes




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ZBP1 (DAI/DLM-1) promotes osteogenic differentiation while inhibiting adipogenic differentiation in mesenchymal stem cells through a positive feedback loop of Wnt/β-catenin signaling




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Dystrophic calcification and heterotopic ossification in fibrocartilaginous tissues of the spine in diffuse idiopathic skeletal hyperostosis (DISH)




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Ionomycin ameliorates hypophosphatasia via rescuing alkaline phosphatase deficiency-mediated L-type Ca<sup>2+</sup> channel internalization in mesenchymal stem cells




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Intronic variant in <i>IQGAP3</i> associated with hereditary neuropathy with proximal lower dominancy, urinary disturbance, and paroxysmal dry cough




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Correction to ‘Genotyping of Malaysian G6PD-deficient neonates by reverse dot blot flow-through hybridisation’




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Why is the United States So Bad at Foreign Policy?

Stephen Walt writes that the United States' unusual historical experience, geographic isolation, large domestic market, and general ignorance have weakened its ability to make viable foreign-policy strategies.




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Accumulating Evidence Using Crowdsourcing and Machine Learning: A Living Bibliography about Existential Risk and Global Catastrophic Risk

The study of existential risk — the risk of human extinction or the collapse of human civilization — has only recently emerged as an integrated field of research, and yet an overwhelming volume of relevant research has already been published. To provide an evidence base for policy and risk analysis, this research should be systematically reviewed. In a systematic review, one of many time-consuming tasks is to read the titles and abstracts of research publications, to see if they meet the inclusion criteria. The authors show how this task can be shared between multiple people (using crowdsourcing) and partially automated (using machine learning), as methods of handling an overwhelming volume of research.




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Why Matter Matters: How Technology Characteristics Shape the Strategic Framing of Technologies

The authors investigate how the executives of the two largest research institutes for photovoltaic technologies — the National Renewable Energy Laboratory (NREL) in Golden, USA and the Fraunhofer Institute for Solar Energy Systems (Fraunhofer ISE) in Freiburg, Germany — have made use of public framing to secure funding and shape the technological development of solar photovoltaic (PV) technologies. The article shows that the executives used four framing dimensions (potential, prospect, performance, and progress) and three framing tactics (conclusion, conditioning, and concession), and that the choice of dimensions and tactics is tightly coupled to the characteristics of the specific technologies pursued by the research institutes.




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Why the U.S. Withdrawal from the Paris Climate Accord is a Mistake

The authors explain why the Trump administration's reiteration of its intent to finalize U.S. withdrawal from the Paris Agreement is a tragic mistake that will weaken us as a nation.




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Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World

To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures.

What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past.




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The Political Power of Proxies: Why Nonstate Actors Use Local Surrogates

Unlike state sponsors, which value proxies primarily for their military utility, nonstate sponsors use proxies mainly for their perceived political value. An analysis of three case studies—al-Qaida in the Arabian Peninsula, the People’s Protection Units in Syria, and Hezbollah in Lebanon—illustrates this argument.




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Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




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Predictors of weight loss after bariatric surgery—a cross-disciplinary approach combining physiological, social, and psychological measures




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Associations between the activity of placental nutrient-sensing pathways and neonatal and postnatal metabolic health: the ECHO Healthy Start cohort




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Active travelling to school is not associated with increased total daily physical activity levels, or reduced obesity and cardiovascular/pulmonary health parameters in 10–12-year olds: a cross-sectional cohort study




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The Political Power of Proxies: Why Nonstate Actors Use Local Surrogates

Unlike state sponsors, which value proxies primarily for their military utility, nonstate sponsors use proxies mainly for their perceived political value. An analysis of three case studies—al-Qaida in the Arabian Peninsula, the People’s Protection Units in Syria, and Hezbollah in Lebanon—illustrates this argument.




hy

Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




hy

Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




hy

Why Matter Matters: How Technology Characteristics Shape the Strategic Framing of Technologies

The authors investigate how the executives of the two largest research institutes for photovoltaic technologies — the National Renewable Energy Laboratory (NREL) in Golden, USA and the Fraunhofer Institute for Solar Energy Systems (Fraunhofer ISE) in Freiburg, Germany — have made use of public framing to secure funding and shape the technological development of solar photovoltaic (PV) technologies. The article shows that the executives used four framing dimensions (potential, prospect, performance, and progress) and three framing tactics (conclusion, conditioning, and concession), and that the choice of dimensions and tactics is tightly coupled to the characteristics of the specific technologies pursued by the research institutes.




hy

Why the U.S. Withdrawal from the Paris Climate Accord is a Mistake

The authors explain why the Trump administration's reiteration of its intent to finalize U.S. withdrawal from the Paris Agreement is a tragic mistake that will weaken us as a nation.




hy

Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World

To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures.

What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past.




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Guidelines and definitions for research on epithelial–mesenchymal transition




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Regulatory myeloid cells paralyze T cells through cell–cell transfer of the metabolite methylglyoxal




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Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




hy

Why Bernie Sanders Will Win in 2020, No Matter Who Gets Elected

Stephen Walt writes that even though Bernie Sanders is out of the presidential race, the time has come for many of the policies that he promoted: Universal Healthcare; Democratic Socialism; Income Redistribution; and Foreign Policy.




hy

Why Matter Matters: How Technology Characteristics Shape the Strategic Framing of Technologies

The authors investigate how the executives of the two largest research institutes for photovoltaic technologies — the National Renewable Energy Laboratory (NREL) in Golden, USA and the Fraunhofer Institute for Solar Energy Systems (Fraunhofer ISE) in Freiburg, Germany — have made use of public framing to secure funding and shape the technological development of solar photovoltaic (PV) technologies. The article shows that the executives used four framing dimensions (potential, prospect, performance, and progress) and three framing tactics (conclusion, conditioning, and concession), and that the choice of dimensions and tactics is tightly coupled to the characteristics of the specific technologies pursued by the research institutes.




hy

Why the U.S. Withdrawal from the Paris Climate Accord is a Mistake

The authors explain why the Trump administration's reiteration of its intent to finalize U.S. withdrawal from the Paris Agreement is a tragic mistake that will weaken us as a nation.




hy

Geopolitical and Market Implications of Renewable Hydrogen: New Dependencies in a Low-Carbon Energy World

To accelerate the global transition to a low-carbon economy, all energy systems and sectors must be actively decarbonized. While hydrogen has been a staple in the energy and chemical industries for decades, renewable hydrogen is drawing increased attention today as a versatile and sustainable energy carrier with the potential to play an important piece in the carbon-free energy puzzle. Countries around the world are piloting new projects and policies, yet adopting hydrogen at scale will require innovating along the value chains; scaling technologies while significantly reducing costs; deploying enabling infrastructure; and defining appropriate national and international policies and market structures.

What are the general principles of how renewable hydrogen may reshape the structure of global energy markets? What are the likely geopolitical consequences such changes would cause? A deeper understanding of these nascent dynamics will allow policy makers and corporate investors to better navigate the challenges and maximize the opportunities that decarbonization will bring, without falling into the inefficient behaviors of the past.




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Using physiologically-based pharmacokinetic modeling to assess the efficacy of glove materials in reducing internal doses and potential hazards of N-methylpyrrolidone during paint stripping