In a 5-4 decision, the Supreme Court sided with four iPhone owners who contend the company has been inflating the prices on the App Store. Current antitrust laws allow the plaintiffs to recover three times the amount of damages.

A richer chat experience was rolled out by Valve last year on PC, but now it's being joined by a 'modernized chat experience' for iOS and Android devices.

Apple's iOS 12 tackles thorny issues of smartphone addiction head-on with Screen Time, and hands users hitherto unknown power with Siri Shortcuts. That's in addition to fun memoji and an already-excellent mobile operating system.

Afraid someone might be able to access your phone and get to your files and pictures? Add an extra layer of security with these apps.

If you already use an iPad to do work or make art, Apple's excellent iPadOS will improve the experience, though it still doesn't provide all functionality of a laptop.

Former Scotland captain Shelley Kerr will replace Anna Signeul as coach after UEFA Women's EURO 2017, the ex-defender saying she is "extremely proud and honoured".

Three national educational funders explain a new program that is highlighting innovative practices in schools around the country.

Academic gender gaps in reading and math follow different paths as American students move from their school years into adulthood, according to new federal data.

Source: www.businessinsider.com - Saturday, May 09, 2020
Dating apps like Tinder, Bumble, and Hinge have reported increased use amid the coronavirus pandemic, while touting virtual dating alternatives for users instead of meeting up in person. Swaths of users are still encouraging matches to break quarantine to have sex and go on dates, despite social distancing guidelines and fines to comply with them. An illustrator on Instagram has been collecting screenshots of these situations, and told Business Insider that users will brand themselves as "badasses," dispute the effectiveness of isolating, and lash out in anger and hurl abusive language when they're rejected. Spokespeople for Grindr, Tinder and Bumble told Business Insider they've informed users to adhere to social-distancing guidelines, but did not respond to inquiries about actions they're taking against users in places where violating lockdown orders can be against the law. Visit Business Insider's homepage for more stories . As millions remain confined to their homes to prevent the spread of coronavirus, the desire for human contact and connection has risen dramatically and led some to search for ways to break those social distancing rules. Popular dating apps — including Tinder , Bumble , and Hinge — have reported significant increases during the outbreak of swiping activity, matches between users, and messages exchanged. It's also led to the introduction of a breed of users who are interested in shirking lockdown orders, an

Saudi Arabia has begun an internal investigation into the disappearance of a prominent journalist at its Istanbul consulate and could hold people accountable if the evidence warrants it, according to a Saudi official.

The attempt by Congo and Rwanda to end the deadly conflict in eastern Congo by a secret presidential deal and military force is failing and must be changed fundamentally by the Kinshasa government and the international community.

Burundi’s year-long crisis has not gone away. It started with President Pierre Nkurunziza’s determination to claim a third term, trampling over the constitutional arrangements that ended a decade-long civil war. Press freedom is a major casualty of the new strife; but the turmoil has also transformed the way in which Burundians get information. For better or worse, social media has filled the vacuum left by the shutting down of the most popular radio stations and forcing out of many of the country’s professional journalists.

The U.S. Education Department says the states need more evidence to use the popular admissions test to measure high school achievement.

The U.S. tests its students more than most nations, but is the deluge of data providing the information schools need?

The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). There is a growing understanding of SARS-CoV-2 in the virology, epidemiology and clinical management strategies. However, no anti-SARS-CoV-2 drug or vaccine has been officially approved due to the absence of adequate evidence. Scientists are racing towards the development of treatment for COVID-19. Recent studies have revealed many attractive threptic options, even if some of them remain to be further confirmed in rigorous preclinical models and clinical trials. In this minireview, we aim to summarize the updated potential approaches against SARS-CoV-2. We emphasize that further efforts are warranted to develop the safest and most effective approach.

Despite the worldwide re-emergence of the chikungunya virus (CHIKV) and the high morbidity associated with CHIKV infections, there is no approved vaccine or antiviral treatment available. We here aim to identify the target of a novel class of CHIKV inhibitors i.e. CHVB series. CHVB compounds inhibit the in vitro replication of CHIKV isolates with 50% effective concentrations in the low micromolar range. A CHVB-resistant variant (CHVB^res) was selected that carried two mutations in the gene encoding nsP1 (responsible for viral RNA capping), one mutation in nsP2 and one mutation in nsP3. Reverse genetics studies demonstrated that both nsP1 mutations were necessary and sufficient to achieve ~18-fold resistance, suggesting that CHVB targets viral mRNA capping. Interestingly, CHVB^res was cross-resistant to the previously described CHIKV capping inhibitors from the MADTP series, suggesting they share a similar mechanism of action. In enzymatic assays, CHVB inhibited the methyltransferase and guanylyltransferase activities of alphavirus nsP1 proteins. To conclude, we identified a class of CHIKV inhibitors that targets the viral capping machinery. The potent anti-CHIKV activity makes this chemical scaffold a potential candidate for CHIKV drug development.

Drug repositioning is the only feasible option to address the COVID-19 global challenge immediately. We screened a panel of 48 FDA-approved drugs against SARS-CoV-2 which were pre-selected by an assay of SARS-CoV and identified 24 potential antiviral drug candidates against SARS-CoV-2 infection. Some drug candidates showed very low micromolar IC50s and in particular, two FDA-approved drugs - niclosamide and ciclesonide – were notable in some respects.

Six sources confirmed Apple changed its mind on end-to-end encrypted backups two years ago following an FBI complaint and concerns users could lose access to their own data.

The precious metal eased for a third day after US equities hit the highest in almost seven weeks as states including Florida took steps toward easing restrictions.

Apple's excellent entry-level desktop video editing application can turn your footage and photos into impressive productions.

For Norwegian international striker Ada Hegerberg, inspiring the next generation of women's players is a personal goal. In an interview which appears in the Women's U17 EURO tournament programme, we hear that the Olympique Lyonnais star wants budding young players to feel her same love of the game.

Effective immediately and for the foreseeable future, the Entrepreneurship and Assistance Clinic is expanding its scope and service offerings to small Pennsylvania businesses, in response to the COVID-19 pandemic.

Happy Valley LaunchBox powered by PNC Bank is accepting applications through May 15 for its Idea TestLab that will now be hosted virtually in June. Open to the community, the four-week Idea TestLab program is designed to help teams evaluate the viability of their business ideas by coaching them through a proven method of customer discovery and problem analysis.

Unit trusts appeal to me because:

If you're running out of room on your Apple Watch, get rid of specific apps and content you no longer need. Here's how to free up space from the Watch app and the device.

With iOS 13.1 and iPadOS, Apple adds an Audio Sharing feature that lets you share with a friend what you're listening to on your Apple AirPods or select Beats headphones.

You can enjoy your AirPods Pro even more if you know how to fully use and customize them. Here are our top tips and tricks to get the most out of Apple’s wireless earbuds.

Want to contribute to Apple's health research studies? You can sign up for programs on women's health, your heart and movement, and hearing using the Research app.

Apple's Shortcuts app can quickly and easily run a host of tasks on your Apple Watch or iOS or iPadOS device. Here's how to create and use shortcuts for Siri.

If you’re having trouble sleeping, you may want to monitor your sleep cycle. Apple Watch makes it easy with these apps.

You'll get a trial, but that's it. If you want any kind of free music, you'll have to stick with iTunes Radio.

If your battery capacity ever drops below 80 percent when you have AppleCare+, you're in luck!

Today, Apple takes on the biggest name in music streaming, Spotify. How do they measure up to each other?

New iPods can be a critical part of Apple's strategy. Just don't think of them as music players.

Apple quietly revealed new iPods today with new colors and better specs.

As the Apple iPod turns 14, we take a look back at its history and influence over the last decade-plus.

The Apple iPod touch is the best media player there is if you don't want a cellular connection.

"It's like a cinderblock," one seven-year-old said of Apple's original MP3 player.

Customers in the U.S. should begin noticing in-store changes starting today.

Streaming services and complicated gadgets aren't for me. Sometimes single-purpose retro tech is all you need.

There's a new iPod touch! A new iPod touch? Sure. It's going to be popular with parents, with people who exercise, and with anyone who wants low-cost access to iMessage and FaceTime.

Apple's 2019 iPod touch is a small, light handheld media player that's terrific for kids and anyone who doesn't want a full-fledged smartphone.

Don't take your safety for granted. These apps, services, and gadgets will help you communicate your location to trusted contacts and get help should trouble arise.

With the best scanning and OCR apps, you can save whiteboard text, business cards, and important documents so that you can not only read them, but also edit them.

Apple Music boasts a deep music well Siri and Apple Watch compatibility, but this well-rounded streaming music service falls just short of joining LiveXLive and Spotify as the best in class.

Google removes the free WireGuard app from the Play Store for having a donation button, reigniting a debate over whether its policy hurts the open-source community.

Free apps are cool, but a few bucks can get you so much more. If you are looking to buy in the Google Play store, here are the best paid Android apps to put on your phone.