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COVID-19 outcomes in patients with hematologic disease




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Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome




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Rituximab for desensitization during HLA-mismatched stem cell transplantation in patients with a positive donor-specific anti-HLA antibody




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Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR




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Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment




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Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells




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WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2




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LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression




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NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas




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Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE)

Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE.




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RNAi against therapeutic targets with short interfering ribonucleic neutrals (siRNNs)

siRNNs could enable RNAi knockdown of therapeutic targets in a broader range of cells and tissue types than siRNA.




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Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor

Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives.




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Angiopoietin 2 (ANG2; ANGPT2); placental growth factor (PGF; PlGF); tissue inhibitor of metalloproteinases 3 (TIMP3)

Mouse studies suggest inhibiting PGF could help treat hypertension.




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Tripartite motif containing 37 (TRIM37)

In vitro and mouse studies suggest inhibiting TRIM37 could help treat breast cancer.




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Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K)

Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy.




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Translational tidbits

Yabao and MRC Technology partner in PD; charities form Neuro-MAP to insource pharma's abandoned compounds; Singapore creates a diagnostic hub; a roundup of public-private partnerships.




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Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity




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Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling




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Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity




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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states




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Reviewer Recognition




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MicroRNA binding site polymorphism in inflammatory genes associated with colorectal cancer: literature review and bioinformatics analysis




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In vivo antitumor activity by dual stromal and tumor-targeted oncolytic measles viruses




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Oncolytic adenovirus encoding LIGHT (TNFSF14) inhibits tumor growth via activating anti-tumor immune responses in 4T1 mouse mammary tumor model in immune competent syngeneic mice




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High-purity orbital angular momentum states from a visible metasurface laser




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Author Correction: Quantum wave–particle superposition in a delayed-choice experiment




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Nintedanib inhibits keloid fibroblast functions by blocking the phosphorylation of multiple kinases and enhancing receptor internalization




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An in vitro Förster resonance energy transfer-based high-throughput screening assay identifies inhibitors of SUMOylation E2 Ubc9




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Compound LM9, a novel MyD88 inhibitor, efficiently mitigates inflammatory responses and fibrosis in obesity-induced cardiomyopathy




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Ex vivo pulsed dendritic cell vaccination against cancer




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Microbiota and colorectal cancer: colibactin makes its mark




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Inducing senescence sensitizes pancreatic tumours to therapies




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Universal screening for hepatitis C virus infection should be linked to universal treatment access




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Author Correction: Management of IBD during the COVID-19 outbreak: resetting clinical priorities




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Effects of acute and repeated treatment with methocinnamox, a mu opioid receptor antagonist, on fentanyl self-administration in rhesus monkeys




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Cannabinoid CB<sub>2</sub> receptors mediate the anxiolytic-like effects of monoacylglycerol lipase inhibition in a rat model of predator-induced fear




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Correction: Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression




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Evaluating the impact of trauma and PTSD on epigenetic prediction of lifespan and neural integrity




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Obesity affects skeletal muscle ketone oxidation




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Obesity and impaired metabolic health in patients with COVID-19




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Sweet signals — gut–brain circuit for sugar identified




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New insights into K<sub>ATP</sub> channel gene mutations and neonatal diabetes mellitus




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Probing nanoscale fluctuation of ferromagnetic meta-atoms with a stochastic photonic spin Hall effect




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Author Correction: Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis




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SIN List criticism based on misunderstandings




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Development of a skin temperature map for dermatomes in individuals with spinal cord injury: a cross-sectional study




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Supporting sexual adjustment from the perspective of men living with spinal cord injury




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Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder




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Associations of interruptions to leisure-time sedentary behaviour with symptoms of depression and anxiety




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Emerging functional connectivity differences in newborn infants vulnerable to autism spectrum disorders