It's a great budget option, unless you're leaking for comfort. Or functionality.

~NSHA

WELCOME to every night in San Francisco.

Falco Pyramid is a dynamic game where you have to protect your base from an advancing wave of multi-colored cubes. The playing field is a pyramid expanding towards you, in which new cubes appear and move towards you. Your task is to shoot multi-colored cubes from a cannon, creating combinations of three or more cubes of the same color. Explosions of cubes destroy them and stop the onslaught from the pyramid. The longer you hold off the onslaught of cubes, the more points you get. But be careful, because the pyramid is constantly expanding, and the cubes are moving faster and faster. Falco Pyramid is a game that requires quick reactions, logical thinking and precise goal setting. Test your skills and hold off the onslaught of cubes in Falco Pyramid!

Experience the nostalgia of gaming's golden age with this classic primitive space arcade game. Perfect for collectors and enthusiasts, this game captures the essence of early arcade fun with its simple yet addictive gameplay and retro aesthetics. Classic Gameplay: Navigate your spaceship through waves of enemies. This game is a must-have for anyone looking to relive the excitement of early arcade gaming or add a piece of gaming history to their collection. Whether you're a seasoned gamer or new to the arcade scene, this game promises hours of fun and challenge. Don’t miss out on owning a piece of arcade history!

Falco Floodfill is an exciting puzzle game that will test your logic and spatial thinking. Your task is to paint the entire field of pixels in one color, changing the color of the original pixel. You have to solve the puzzle by choosing the right pixel to start the flooding. Click on the pixel, and the color will spread to neighboring pixels of the same color, gradually filling the entire field. In Falco Floodfill, you have to look for optimal paths and strategies to paint the entire field with a minimum number of clicks. Test your puzzle-solving skills and immerse yourself in the colorful world of pixels in Falco Floodfill!

Falco Trains is a puzzle game where you become a real train dispatcher. Your task is to create a smooth movement of trains on a railway junction, managing their movement and ensuring safety. Each train has a given route, and you need to correctly direct it at the junction so that it can continue its journey without colliding with other trains. In Falco Trains, you will find a variety of difficulty levels, with each of which the number of trains and the complexity of the routes increases. You will have to use logical thinking and strategic skills to ensure the smooth movement of all the trains. Test your train management skills and become a master dispatcher in Falco Trains!

As part of CC’s renewed commitment to investing in the core open infrastructure it stewards, we are excited to announce several updates to our legal team.  Sarah Hinchliff Pearson is returning to Creative Commons as General Counsel. She will manage in-house legal work and play a leading role in shaping CC’s stewardship program and its…

The post CC Welcomes Sarah Pearson Back as General Counsel appeared first on Creative Commons.

Amid the evolving landscape of U.S.-China trade relations, CATL, one of the world’s largest battery manufacturer, has expressed interest in establishing a manufacturing plant in the United States. What Happened: Robin Zeng, the founder and chairman of CATL, shared this perspective in a recent…

In This Article: DENPASAR, Indonesia (AP) — Several international airlines canceled flights to and from Indonesia’s tourist island of Bali on Wednesday as an ongoing volcanic eruption left travelers stranded at airports. Indonesia’s Mount Lewotobi Laki Laki volcano on the remote island of Flores…

The post Tips, Tricks, and Shortcuts for Unlocking Elden Ring’s Shadow of the Erdtree DLC appeared first on Xbox Wire.

In this review we are taking a look at the ProArt LC 360, a 360mm all-in-one cooler for your CPU that brings in some outside help from Alphacool for the fan solution. Taking design queues from the existing LC 420, the LC 360's smaller radiator footprint allows for use in many more case options, while still promoting good performance.

The post ASUS ProArt LC 360 Liquid CPU Cooler Review appeared first on ThinkComputers.org.

By Keegan Kelly Published: November 11th, 2024

A commitment to the liberal arts is at the core of Princeton University's mission. A new cohort of outstanding postdocs has joined the Society of Fellows for three years of teaching and research.

About the Event Two of today’s finest string quartets become even more than the sum of their parts in octets by Felix Mendelssohn and George Enescu as they return to Princeton University Concerts the evening prior to heading to Carnegie Hall. These monumental works—each, incredibly, written by the prodigious composers in their teens—are quintessential representations of the form, showcasing the sonic power and rich, multilayered possibilities of an octet configuration. This event is presented by Princeton University Concerts. For a full event listing and tickets, please visit this link.

Mud volcanoes are formations created by the geological emission of liquids and gases. They are frequently associated with earthquake zones, and when they erupt, they release an often acidic slurry as well as methane and other hydrocarbon gases. Some mud volcanoes also spew flames when they erupt, though the volcanoes themselves tend to be relatively cool. A 2006 drilling accident in Indonesia created a mud volcano that inundated a number of villages and displaced how many people?

Eight bikes, four testers, and some of the best trails in the world.
( Photos: 19, Comments: 342 )

Explore these NOVA resources to better understand the volcanology behind Tonga’s massive undersea eruption in January.

The trails through our public lands weren’t designed for wheelchairs, but new wheelchairs are designed for those trails. National Park Service accessibility specialist Quinn Brett wants parks to catch up with wheelchair technology, increasing access to American wilderness.

Over a dozen flights cancelled or delayed between Bali and Australia

The following article, 7 Bad Signs for Democrats: A Satirical Take on America’s Return to Normalcy, was first published on The Black Sphere.

Yes, the Democrats got shellacked in the last election. And while that’s a breath of fresh air, it’s hardly the only sign that the political winds are changing.

Continue reading 7 Bad Signs for Democrats: A Satirical Take on America’s Return to Normalcy ...

A capsule sent to bring back two astronauts stranded on the International Space Station has docked.

Molly McGregor, 29, was fined £450 for not showing her railcard during a rail journey in May.

There is now a department in Scotland Yard that is dedicated to enforcing hate speech law on telephones. They can and have come to citizens’ homes to arrest them for hate speech. They do not have enough manpower to keep a Muslim from knifing you on the street in London, but they can keep you from commenting about Muslim primitives on Facebook from your home.

The post Welcome to 1984. Somewhere, George Orwell is crying himself to sleep appeared first on Powdered Wig Society.

Australian airlines say it is unsafe to fly after Mount Lewotobi Laki-laki spewed ash.

Trailblazing referee Rebecca Welch says she hopes "somebody else picks up the legacy" as she is inducted into the National Football Museum's Hall of Fame.

Former referee Rebecca Welch talks to BBC Sport's Emma Sanders after being inducted into the Hall of Fame at the National Football Museum.

Taylor Swift has made a habit of cheering for the Kansas City Chiefs since she began dating NFL star Travis Kelce.

In their comment (1) on our publication (2), the authors make two points: (i) they raise concerns about the possible effect of residual NONOate in our study, and (ii) they promote nitrosylcobalamin (NOCbl) supplied by their own company. Both points lack merit for the following reasons. The authors make the astonishing claim that the spectra of nitric oxide (NO•) and cobalamins overlap. Unlike NO•, cobalamin absorbs in the visible region, permitting unequivocal spectral assignment of NOCbl as reported (3). We demonstrated that whereas NOCbl is highly unstable in solution, it is stabilized by the B12 trafficking protein CblC. So even if present, residual NONOate (which is unstable at neutral pH and is removed during the work-up (3)) could not account for the observed difference.The authors then misrepresent our synthetic method, claiming that anaerobic conditions were used to generate nitrocobalamin (NO2Cbl), which results in the transient formation of NOCbl. We synthesized NO2Cbl aerobically using nitrite as described (4); NOCbl is not an intermediate in this ligand exchange reaction. The aerobic instability of NOCbl has been rigorously described by inorganic chemists (3, 5) and raises obvious questions about its purported biological effects as exemplified by the authors' own 2003 JBC publication, which was later withdrawn.As to promoting NOCbl from their company, the authors refer to a synthetic route from a mixture of NO• gas and aquocobalamin. The authors' method (6) has been described as “dubious” by chemists (5). Whereas DEAE NONOate used in our method is widely known as an NO• donor,...

After a thorough read of this paper (1), we wish to clarify that the authors' anaerobic method of synthesis for the production of nitrocobalamin results in the transient formation of nitrosylcobalamin, an unstable intermediate upon exposure to air. We concur that the authors' method results in the production of nitrocobalamin based on the UV-visible data as shown. The authors' adapted anaerobic method consists of mixing hydroxocobalamin hydrochloride with diethylamine NONOate diethylammonium salt in aqueous solution. Of concern, the UV spectrum of nitric oxide overlaps that of all cobalamin species under anaerobic conditions, making any assignments of the binding of nitric oxide to hydroxocobalamin suspect (2). Additionally, the use of acetone to precipitate the authors' product causes precipitation of diethylamine NONOate, resulting in an impure product. As a result, its utility for drawing experimental conclusions is faulty.The product from the authors' anaerobic synthetic method has not been assessed for purity, and the synthetic method itself has not been validated using a stability-indicating method as required by the International Conference on Harmonization (ICH) (ICH Q2B, Validation of Analytical Procedures) methodology, which is a hallmark for analytical characterization. Our nitrosylcobalamin synthesis involves reacting nitric oxide gas with hydroxocobalamin acetate as a heterogeneous mixture in a non-electron-donating solvent followed by rotary evaporation. Our nitrosylcobalamin product is stable in air, releases nitric oxide gas in situ (3), and meets ICH stability guidelines (4). Additionally, our nitrosylcobalamin product demonstrates biological activity, which has not been observed for nitrocobalamin (3, 5).

Jonathan C. Trinidad
Aug 1, 2012; 11:215-229
Research

Jeffrey C. Silva
Jan 1, 2006; 5:144-156
Research

Chatham House welcomes 2024 interns News release jon.wallace 25 October 2024

An internship at Chatham House offers an invaluable learning experience through a six-month placement in one of our teams.

Chatham House is excited to welcome the 2024 cohort to the Molchanov Sustainability Internship Programme. 

Introduced in January 2021, the programme has been made possible following the gift of Pavel Molchanov, to support the next generation of leaders in sustainability. 

The internships grant practical learning opportunities at a world-famous think-tank, helping a new generation of policymakers understand how to shape policy, influence debate, and create meaningful change towards a sustainable future. 

This autumn, Chatham House staff in six departments are delighted to welcome interns to their teams: 

Aisha Abdirahman will work with the Environment and Society Centre, Kendall Spence with the Africa Programme, Matthew Harris with the International Affairs journal, Noor Elgallal with the Middle East and North Africa Programme, Phoebe Hardingham with the Russia and Eurasia Programme, and Thomas Maddock with the Europe Programme.

For more information about the internships, please contact the Academy team.