or

DEVICES AND METHODS FOR SAMPLE CHARACTERIZATION

Devices and methods for characterization of analyte mixtures are provided. Some methods described herein include performing enrichment steps on a device before expelling enriched analyte fractions from the device for subsequent analysis. Also included are devices for performing these enrichment steps.




or

ELECTRICAL SENSOR FOR FLUIDS

An electrical sensor for sensing electromagnetic properties of process fluids in a dialysis machine or a similar medical device can include a probe for interfacing with the fluids that is made from electronic fabric materials. The electronic fabric probe can include one or more conductors embedded in a non-conductive fabric layer. The electronic fabric probe is accommodated an enclosure which establishes a flow path with respect to the probe to establish fluid contact between the process fluids and the conductors. The conductors can apply or sense current and/or voltage with respect to the fluid. A portion of the electronic fabric probe can be disposed externally of the enclosure to provide electronic communication externally of the enclosure.




or

SYSTEMS AND METHODS FOR MULTIFUNCTIONAL VOLUMETRIC FLUID CONTROL

Systems and methods for controlling fluid movement and volumes of fluid between a subject and a controlled compliant flow path. The controlled compliant flow path has a means for selectively metering in and metering out fluid from the controlled compliant flow path. An extracorporeal flow path is in fluid communication with the controlled compliant flow path across a semi-permeable membrane where the extracorporeal flow path has a first terminal end and a second terminal end.




or

PACKING SYSTEM AND METHOD FOR CHROMATOGRAPHY COLUMNS

The invention relates to a method for providing an aseptic chromatography column, said method comprising the steps of: pre-sterilize an empty chromatography column;pre-sterilize a chromatography medium;introducing the pre-sterilized chromatography medium into the pre-sterilized chromatography column using aseptic equipment, thereby providing an aseptic chromatography column comprising chromatography medium.




or

STACKABLE PLANAR ADSORPTIVE DEVICES

A lattice and distribution network for a stackable chromatography cassette comprising: a peripheral seal;at least one screen forming the lattice surrounded by the peripheral seal, each at least one screen comprising a plurality of struts in a latticed arrangement;a first internal distribution network fluidly coupled to the lattice and surrounded by the peripheral seal;a second internal distribution network disposed opposite the first internal distribution network, fluidly coupled to the lattice and surrounded by the peripheral seal;wherein a direction of fluid flow is established from the first internal distribution network through the lattice to the second internal distribution network; andwherein preferential streamlines are minimized.




or

FLUID REMOVAL APPARATUS FOR USE WITH A WEIR TANK

A separation apparatus that includes a weir tank having a plurality of cells and fluid removal apparatus for each cell to remove the fluid from each cell. The fluid removal apparatus includes an actuator and an extension arm whose movement is caused by the actuator. In addition to the actuator and the extension arm, the fluid removal apparatus includes a plunger attached to the extension arm for selectively engaging a first opening in each cell. Furthermore, a method of removing fluid from the separation apparatus via the fluid removal apparatus.




or

FILTER METHOD FOR FILTERING A FLUID AND FILTERING DEVICE FOR FILTERING A FLUID

a filtering method, with which a fluid to be filtered is led through a filter (4), the filter (4) is back-flushed at regular time intervals and a pre-treatment agent is added to the fluid at the entry side of the filter. A process variable which describes the efficiency of the filtration is continuously computed during the filtration, and a metering quantity of the pre-treatment agent is reset on the basis of the values for the process variable or a characteristic values derived from this.




or

REVERSE OSMOSIS WATER FILTRATION DEVICE WITH WATER STORAGE FUNCTION

A reverse osmosis (RO) water filtration device includes a body, a RO cartridge, a first cartridge, a second cartridge and a storage tank all mounted inside the body. Water to be filtered sequentially goes through a water inlet of the RO water filtration device, the first cartridge, the RO cartridge, the storage tank, the second cartridge, and a faucet to get the water filtered. The storage tank provides additional water supply when the pressure between the faucet and RO cartridge is below the water pressure inside the storage tank to increase water volume upon opening a faucet.




or

PROCESS FOR INHIBITING SCALE FORMATION WITH UV LIGHT

A process for inhibiting formation of calcium scale in a reverse osmosis desalination membrane during desalination involving desalinating an aqueous salt solution comprising water, sodium chloride, calcium chloride, and sodium bicarbonate with the reverse osmosis desalination membrane, while concurrently irradiating the aqueous salt solution with a UV light source that emits UV light with a wavelength of 250-400 nm. Scale formation is inhibited by treating a salt solution with the UV light in a continuous or a non-continuous process.




or

TANGENTIAL FILTER WITH A SUPPORTING ELEMENT INCLUDING A SET OF CHANNELS

A tangential filter for filtration of a fluid includes a support element, wherein, along a transverse plane perpendicular to the central axis of the support element a) the support element includes in its central portion only inner channels that do not share a common wall with its outer surface, the inner channels having a substantially equivalent hydraulic diameter, b) the support element includes peripheral channels, including at least first and second adjacent peripheral channels, each of the two channels sharing a common wall with the outer surface, c) the ratio of the hydraulic diameter of the first channel to the hydraulic diameter of the second channel is greater than or equal to 1.1, d) the number of peripheral first channels is greater than or equal to the number of peripheral second channels, e) the second channel has a hydraulic diameter substantially identical to the hydraulic diameter of the inner channels.




or

THERMO-SENSITIVE WATER ABSORBENT, METHOD OF WATER TREATMENT, AND WATER TREATMENT APPARATUS

A thermo-sensitive water absorbent is used as a draw material in production of fresh water by a forward osmosis process. The thermo-sensitive water absorbent has a cloud point, and coagulates when heated, the thermo-sensitive water absorbent being a block copolymer containing at least a hydrophobic part and a hydrophilic part, having a glycerin structure as a basic structure, and including an ethylene oxide group and a group consisting of propylene oxide and/or butylene oxide.




or

Systems and arrangements for mitigating environmental damage caused by storm water carried pollution

A pollution mitigation system is disclosed. The system can include a valve forming a passage the valve installable to form an orifice in a storm drain retention chamber that passes storm water into a conduit of a storm water management system. The valve having a stem connected to a closure member that can plug the orifice. The valve can have a spring loaded actuator that can move the closure member into a closed position. The system can also include a node such as a wireless sensor node or a mote that has sensors, a transceiver, an antenna, a microcontroller, memory, an energy source and at least one output to control movement of the closure member via the preloaded actuator. The node can have an output that provides the stimulus to the preloaded actuator to cause the preloaded actuator to move the closure member to a position that obstructs the passage in response to either the sensor or a transmission from a mobile telephone such as a cell phone or a smartphone.




or

Method of degrading perfluorinated compound

The present disclosure relates to the technical field of degradation of persistent pollutants and discloses a method for efficiently degrading a perfluorinated compound (PFC), through which the problems of harsh reaction conditions and less high defluorination rate existing in prior-art methods for degrading PFCs are solved. In the present disclosure, a 3-indoleacetic acid (IAA) solution is irradiated with 254 nm UV light to generate hydrated electrons, with which the PFC are degraded by reduction under an aerobic condition, where an organo-modified montmorillonite is added to provide a reaction microzone, so the degradation and defluorination effects of the hydrated electrons for the PFC are greatly improved. The method for degrading a PFC according to the present disclosure is not affected by the pH of and the dissolved oxygen in the solution and less affected by the humic substances in a water body, thereby overcoming the defects in existing methods for degrading PFCs with hydrated electrons while the degradation efficiency is ensured. Therefore, the present disclosure is of great application value.




or

DEVICE AND METHOD FOR TREATING LIQUIDS BY MEANS OF OZONE

A method for treating contaminated liquids in a flow by ozone, wherein the ozone is fed in gas form into the flow at one point and then is mixed into the flow in stages by mixers following one another in the flow direction, so that an absolute quantity of introduced ozone increases after each mixer until a feed efficiency of more than 95 percent is reached.




or

METHOD TO DISPERSE BYPRODUCTS FORMED IN DILUTION STEAM SYSTEMS

Disclosed herein are methods for reducing fouling caused by process water present within a water recycling loop of a pyrolysis plant. The process water includes water, a pygas, and in some cases pygas byproducts. Fouling is caused by phase separation and accumulation of materials from the process water on equipment surfaces. The method includes applying a total of about 5 ppm to 500 ppm of one or more antifouling polymers to the process water to form a treated process water. The one or more antifouling polymers are selected from the group consisting of copolymers of unsaturated fatty acids, primary diamines, and acrylic acid; copolymers of methacrylamidopropyl trimethylammonium chloride with acrylic acid and/or acrylamide; copolymers of ethylene glycol and propylene glycol; and blends of two or more thereof.




or

PLANT AND METHOD FOR MELTING AND CLEANING OF SNOW AND ICE

Plant for melting and cleaning of snow and ice, distinguished in that the plant comprises a means for melting using enthalpy of a water source in order to melt snow and ice, and a means for cleaning for cleaning out the pollution from the water phase that contains the melted snow and ice. Method for melting and cleaning of snow and ice, using the plant according to the invention.




or

Waste and/or Hazardous Liquid Containment and Collection System

5 A liquid cleaning system rests on a surface having a non-porous material covering and a drain. A lower plate layer and an upper plate layer each have runners arranged in a grid. The lower plate layer rests upon the surface and the upper plate layer rests upon the lower plate layer offset at an angle with respect to the grid of the lower plate layer. An upper layer covers the upper plate layer and has a plurality of holes for the passage of fluids into the liquid cleaning system. As liquid enters the liquid cleaning system through the holes, the liquid traverses the grid of the lower plate layer and the grid of the upper plate layer flowing towards the drain, and contaminants within the liquid collect within the grid of the lower plate layer and the grid of the upper plate layer.




or

The East Bay Hip-Hop Scene Will No Longer Be Ignored

While the region's influence on mainstream hip-hop has gone overlooked for decades, a new generation of break-out artists are reclaiming their musical heritage and drawing national attention back to the area. In the hours leading up to their showcase at The Chapel in San Francisco's Mission District in late February, members of HBK Gang milled about the overcrowded green room, laughing, dancing, and taking selfies. The effervescent supergroup consists of more than a dozen East Bay rappers, singers, and producers mostly in their early twenties.…



  • News & Opinion/Feature

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May Day Protests Begin With Port Shutdown

Members of the International Longshore and Warehouse Union Local 10 who handle cargo at the Port of Oakland — one of the busiest US seaports — stopped work across the Bay Area today to protest against police brutality. Rallying near the gate of an idle port terminal, Bay Area longshore workers were joined by labor leaders representing BART train operators, city and county workers, port workers from Los Angeles, as well as hundreds of community members.

“There is an epidemic of police terror,” said Jack Heyman, a retired Oakland port worker.…




or

Warriors Parade Draws Massive Crowd



Warriors fans from around the Bay Area flocked to Oakland for a parade through downtown and a rally on the shore of Lake Merritt. The massive crowd spilled into the streets, stopping traffic in many parts of the city, as team members, coaches, staff, and members of government gave speeches to commemorate the Warriors' historic championship.…




or

Jet Martinez Brings a Floral Green Flash to Downtown Oakland

Last week, Oakland artist Jet Martinez finished his largest mural yet, on the side of the I. Magnin Building in downtown Oakland — to stunning effect. 

The Mexico-born artist  is known internationally for his gorgeous floral patterning inspired by motifs in Mexican folk art. But, according to a recent statement released about his new mural, he recently decided he wanted to contribute more directly to the community in which he lives by doing more local art.…



  • Blogs/Arts & Music

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Treasure Island Music Festival Made a Valiant Attempt to Weather the Storm

Kamaiyah, Ice Cube, How to Dress Well, and Sigur Rós played in the rain despite the many delays, cancelations, and technical difficulties. Treasure Island promised one of its best lineups yet for its tenth anniversary, but severe weather literally rained on everyone's parade. Many performances were delayed or canceled, often with little communication to the public on Saturday.…




or

Bay Area Activists Protest Peter Thiel's Partnership With Immigration and Customs Enforcement

'Don’t build technology for Mordor.' On Saturday at Peter Thiel’s San Francisco home overlooking the Bay, protesters demonstrated against a collaboration between Immigration and Customs Enforcement and Palantir Technologies, a data-mining firm that Thiel co-founded. As reported in The Intercept, ICE will be using a new Palantir product called Investigative Case Management to to aid in its expanded deportation mission.…



  • News & Opinion/News

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Photos from the ANSWER and Indivisible Counter-Protests Against ACT for America's 'March Against Sharia'

ACT for America, which the Southern Poverty Law Center has designated as an anti-muslim hate group, showed up on Saturday morning in cities nationwide, dubbing its protest a "March Against Sharia." Berkeley was spared, but the group appeared in nearby Santa Clara, and in Roseville, a suburb of Sacramento.…




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Photos: Warriors Celebrate Second Title in Three Years with Parade and Rally in Oakland

The Golden State Warriors paraded for the second time in three years in downtown Oakland yesterday. Players rode by in topless busses, paired with teammates and families, along with coaches, members of the team's ownership group, and of course the odd ambassadorial pairing of Mayor Libby Schaaf and MC Hammer.…




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Photos from the Warriors' 2018 Championship Parade in Oakland

Here are photos from today's Warriors' championship parade.




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Review: J Balvin Proved Why He's One of the World's Biggest Latinx Acts at Oracle Arena


The last time J Balvin was at Oracle arena was back on Feb. 15, 2015 when he was the opening act for Pitbull and Enrique Iglesias' joint tour. I was at that show with my mom as my date, and vividly remember her saying, “one day he’s going to headline his own tour here.” I brushed off her comment, it wasn’t that I didn’t believe that he was talented.…



  • Blogs/Arts & Music

or

Careful What You Wish For

Fantasy Island is back. Who wished for that? The people who tell you "there are more tears shed over answered prayers" are people who weren't going to answer your prayers anyway. I was a non-TV watching snob during Fantasy Island's six-year reign on TV, as it impressed upon its viewers the importance of not asking for trouble by wishing for anything.…




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Kitchen Story Tells a Familiar Yet Refreshing Tale

The 10th restaurant from Bay Area restaurateur Hoyul Steven Choi offers a creative take on Korean-infused cuisine. You'd think that after opening nearly a dozen successful restaurants in the ultra-competitive Bay Area dining scene, restaurateur Hoyul Steven Choi would have calmed his new restaurant jitters by now. But Choi says that's not the case.…




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Which Restaurants Are Open For Deliveries and Take-Out?

The chamber of commerce is maintaining a list of local eateries still open for business. The Oakland Chamber of Commerce has compiled a list of more than 175 Oakland restaurants offering takeout or home delivery. The City of Alameda had a similar idea, and has created a website listing about 85 restaurants.…




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Evidence Suggests That Sheltering-In-Place is Working

Scroll from the bottom up to read in chronological order.…




or

SYSTEMS FOR HANDLING MICROFLUIDIC DROPLETS

The invention generally relates to assemblies for displacing droplets from a vessel that facilitate the collection and transfer of the droplets while minimizing sample loss. In certain aspects, the assembly includes at least one droplet formation module, in which the module is configured to form droplets surrounded by an immiscible fluid. The assembly also includes at least one chamber including an outlet, in which the chamber is configured to receive droplets and an immiscible fluid, and in which the outlet is configured to receive substantially only droplets. The assembly further includes a channel, configured such that the droplet formation module and the chamber are in fluid communication with each other via the channel. In other aspects, the assembly includes a plurality of hollow members, in which the hollow members are channels and in which the members are configured to interact with a vessel. The plurality of hollow members includes a first member configured to expel a fluid immiscible with droplets in the vessel and a second member configured to substantially only droplets from the vessel. The assembly also includes a main channel, in which the second member is in fluid communication with the main channel. The assembly also includes at least one analysis module connected to the main channel.




or

METHODS AND COMPOSITIONS FOR PREDICTING TOBACCO USE

Provided herein are methods of reliably determining whether or not an individual is a user of tobacco.




or

Process, Apparatus or System and Kit for Classification of Tumor Samples of Unknown and/or Uncertain Origin and Use of Genes of the Group of Biomarkers

The present invention refers to a process for classifying tumor samples of unknown and/or uncertain primary origin, specifically including the steps of obtaining patterns of biological activity modulation of tumor of unknown and/or uncertain primary origin and comparing them to an specific and unique group of biomarkers which determine the profiles of biological activity modulation of known origin tumors. The present invention belongs to the molecular biology and genetics field.




or

METHODS FOR PREDICTING THE SURVIVAL TIME OF PATIENTS SUFFERING FROM CANCER

The present invention relates to methods for predicting the survival time of patients suffering from cancer. Said methods are based on the quantification and analysis of the cell free nucleic acids that are present in a sample from the patient and typically include the determination of the level of the mutant nucleic acid which contains a mutation of interest, the calculation of the mutation load for said mutation of interest, the calculation of the DNA integrity index or a combination thereof.




or

METHODS AND COMPOSITIONS RELATING TO FUSIONS OF ALK FOR DIAGNOSING AND TREATING CANCER

Disclosed are methods and compositions for detecting the presence of a cancer in a subject and assessing the efficacy of treatments for the same. The disclosed method use reverse transcription polymerase chain reaction (RT-PCR) and multiplex polymerase chain reaction techniques as well as Template Exchange Extension Reaction (TEER) to detect the presence of point mutations, truncations, or fusions of anaplastic lymphoma kinase.




or

VIRUS CAUSING RESPIRATORY TRACT ILLNESS IN SUSCEPTIBLE MAMMALS

The invention relates to the field of virology. The invention provides an isolated essentially mammalian negative-sense single-stranded RNA virus (MPV) within the subfamily Pneumovirinae of the family Paramyxoviridae and identifiable as phylogenetically corresponding to the genus Metapneumovirus and components thereof.




or

COMPOSITIONS, METHODS, AND SYSTEMS FOR TISSUE FIXATION

The present disclosure relates to use of high-concentration aldehyde-based fixatives to fix tissue samples. Aldehyde concentrations are selected that significantly increase rate of diffusion of the fixative solution into the tissue. When combined in the cold-temperature step of a two-temperature fixation, a substantial improvement in the preservation of post-translationally modified proteins is achieved.




or

Liquid to Liquid Biological Particle Concentrator with Disposable Fluid Path

Highly efficient and rapid filtration-based concentration devices, systems and methods are disclosed with sample fluidic lines and a filter packaged in a disposable tip which concentrate biological particles that are suspended in liquid from a dilute feed suspension. A sample concentrate or retentate suspension is retained while eliminating the separated fluid in a separate flow stream. The concentrate is then dispensed from the disposable tip in a set volume of elution fluid. Suspended biological particles include such materials as proteins/toxins, viruses, DNA, and/or bacteria in the size range of approximately 0.001 micron to 20 microns diameter. Concentration of these particles is advantageous for detection of target particles in a dilute suspension, because concentrating them into a small volume makes them easier to detect. All conduits by which the disposable tip attaches to the instrument are combined into a single connection point on the upper end of the tip.




or

Enhancing Flow Cytometry Discrimination with Geometric Transformation

In flow cytometry, particles (2) can be distinguished between populations (8) by combining n-dimensional parameter data, which may be derived from signal data from a particle, to mathematically achieve numerical results representative of an alteration (48). An alteration may include a rotational alteration, a scaled alteration, or perhaps even a translational alteration. Alterations may enhance separation of data points which may provide real-time classification (49) of signal data corresponding to individual particles into one of at least two populations.




or

MULTI-COLOR FLOW CYTOMETRIC ANALYSIS OF SAMPLES WITH LOW CELL NUMBERS

Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include contacting a biological sample having cells with an assay reagent that includes one or more analyte-specific binding members to produce a biological sample assay composition and introducing the biological assay composition into an inlet of a flow cytometer having an integrated acoustic separator. Systems, including a flow cytometer with integrated acoustic separator having one or more acoustic concentrator devices suitable for practicing the subject methods are also described.




or

ON-CHIP MOLECULE FLUORESCENCE DETECTION

A semiconductor device used for fluorescent-based molecule detection and a method for manufacturing the same are provided. The semiconductor device has a fluid channel layer defining a fluid channel through which a sample stream flows. A target cell coupled with a fluorescent source is contained by the sample stream. The semiconductor device also has an excitation light source for generating excitation light that reaches the target cell coupled with the fluorescent source to generate fluorescent light. The semiconductor device also has a light filter layer for permitting the fluorescent light to pass through and to block the excitation light and a light detection layer for detecting the fluorescent light. The functional components of the device are highly integrated. Leakage of the excitation light and background noise into the light detection component can be minimized to improve the quality of detection.




or

MICROTENTACLE IMAGING IN PATIENT TUMOR SAMPLES

The present invention provides a method for imaging microtentacles on isolated, living, non-adherent primary tumor cells from a cancer subject comprising: i) obtaining one or more living, non-adherent primary tumor cells that has been isolated from a solid tumor from the subject; and ii) imaging the one or more living, non-adherent primary tumor cells and detecting the microtentacles.




or

Screening Assay for Choice of Prebiotic to Prevent/Treat Gastrointestinal and Systemic Diseases

An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.




or

LIGHT HARVESTING MULTICHROMOPHORE COMPOSITIONS AND METHODS OF USING THE SAME

Light harvesting luminescent multichromophores that are configured upon excitation to transfer energy to, and amplify the emission from, an acceptor signaling chromophore in energy-receiving proximity therewith are provided. Also provided are compositions for labelling a target. The labelling composition may include a donor light harvesting multichromophore and an acceptor signaling chromophore in energy-receiving proximity to the donor light harvesting multichromophore. Also provided is an aqueous composition for labelling a target, including: a donor light harvesting multichromophore; an acceptor signaling chromophore in energy-receiving proximity therewith; and a sensor biomolecule. Methods for using the subject compositions are also provided.




or

NOVEL METHOD FOR DETECTING DETECTION OBJECT IN SAMPLE, AND DETECTION KIT USING SAME

The present invention relates to a novel method for detecting a detection object in a sample, and a detection device using the same. The detecting method of the present invention uses a “bridge composite” in which gold nanoparticles and an antibody specific to a detection object are coupled in order to induce a sufficient coupling reaction between the antibody and the detection object, thereby improving reactivity. Accordingly, since excellent resolution is provided, the method of the present invention has advantages of enabling accurate concentration measurement of a detection object in a sample, and amplifying a measurement signal. In addition, the method of the present invention can effectively detect small molecules such as hormones, vitamins, etc. having a small molecular weight.




or

MOLECULAR METHODS FOR ASSESSING POST KIDNEY TRANSPLANT COMPLICATIONS

Methods of screening for expression of an RNA associated with a post-kidney transplant complication include collecting vesicles from urine, isolating vesicle-associated RNA, and analyzing expression patterns. In particular, AIF1, BTN3A3, CCL5, CD48, HAVCR1, or SLC6A6 mRNA expression patterns are analyzed.




or

SENSING SENSOR AND SENSING DEVICE

A sensing sensor includes a wiring board, a piezoelectric resonator, a channel forming member, a case body, and a regulating portion. The case body houses the wiring board, the piezoelectric resonator, and the channel forming member. The case body includes a window faced to a region including the output terminal on the another surface side of the wiring board and an injection port supplying a supply liquid to the one end side of the channel. The regulating portion is disposed in the case body. The regulating portion regulates the wiring board from the one surface side when the wiring board is pressed from the another surface side. The piezoelectric resonator is pressed against the surrounding portion by the output terminal being pressed from the another surface side.




or

DETECTION OF BIOAGENTS USING A SHEAR HORIZONTAL SURFACE ACOUSTIC WAVE BIOSENSOR

Viruses and other bioagents are of high medical and biodefense concern and their detection at concentrations well below the threshold necessary to cause health hazards continues to be a challenge with respect to sensitivity, specificity, and selectivity. Ideally, assays for accurate and real time detection of viral agents and other bioagents would not necessitate any pre-processing of the analyte, which would make them applicable for example to bodily fluids (blood, sputum) and man-made as well as naturally occurring bodies of water (pools, rivers). We describe herein a robust biosensor that combines the sensitivity of surface acoustic waves (SAW) generated at a frequency of 325 MHz with the specificity provided by antibodies and other ligands for the detection of viral agents. In preferred embodiments, a lithium tantalate based SAW transducer with silicon dioxide waveguide sensor platform featuring three test and one reference delay lines was used to adsorb antibodies directed against Coxsackie virus B4 or the negative-stranded category A bioagent Sin Nombre virus (SNV), a member of the genus Hantavirus, family Bunyaviridae, negative-stranded RNA viruses. Rapid detection (within seconds) of increasing concentrations of viral particles was linear over a range of order of magnitude for both viruses, although the sensor was approximately 50×104-fold more sensitive for the detection of SNV. For both pathogens, the sensor's selectivity for its target was not compromised by the presence of confounding Herpes Simplex virus type 1. The biosensor was able to detect SNV at doses lower than the load of virus typically found in a human patient suffering from hantavirus cardiopulmonary syndrome (HCPS). Further, in a proof-of-principle real world application, the SAW biosensor was capable of selectively detecting SNV agents in complex solutions, such as naturally occurring bodies of water (river, sewage effluent) without analyte pre-processing.




or

COMPOSITIONS AND METHODS FOR AUTOIMMUNE DISEASE

Methods and compositions are described for categorizing and treating autoimmune disease, using single cell network profiling (SCNP), where activation levels of one or more activatable elements are determined in single cells, with or without modulation, to categorize or determine treatment for the autoimmune disease.