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Élémens d'hygiène, ou de l'Influence des choses physiques et morales sur l'homme, et des moyens de conserver la santé / par Étienne Tourtelle.

Paris : Rémont, 1815.




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The ear : its anatomy, physiology, and diseases : a practical treatise for the use of medical students and practitioners / by Charles H. Burnett.

London : J. & A. Churchill, 1877.




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Education and culture as related to the health and diseases of women / by Alex. J.C. Skene.

Detroit, Mich. : G.S. Davis, 1889.




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The effect of the cold weather in the early part of 1895 on the admission of medical cases into the Royal Edinburgh Infirmary. With a note on some earlier periods of severe weather / by A. Lockhart Gillespie.

London : Kenny & Co, [1895?]




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Ein Beitrag zur Lehre von den Lesestörungen auf Grund eines Falles von Dyslexie / von S. Weissenberg.

Berlin : L. Schumacher, 1890.




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Electrical and anatomical demonstrations : delivered at the School of Massage and Electricity, in connection with the West-End Hospital for Diseases of the Nervous System, Paralysis and Epilepsy, Welbeck Street, London. A handbook for trained nurses and m

London : J. & A. Churchill, 1887.




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Electricity in the diseases of women : with special reference to the application of strong currents / by G. Betton Massey.

London : Philadelphia, 1889.




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Elements of materia medica : containing the chemistry and natural history of drugs, their effects, doses, and adulterations : with observations on all the new remedies recently introduced into practice, and on the preparations of the British Pharmacopoeia

London : J. Churchill, 1864.




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Elements of medical jurisprudence; or, A succinct and compendious description of such tokens in the human body as are requisite to determine the judgment of a coroner, and courts of law, in cases of divorce, rape, murder, &c : To which are added, Dire

London : printed for J. Callow, 1814.




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Elements of obstetric medicine : with the description and treatment of some of the principal diseases of children / by David D. Davis.

London : Taylor and Walton, 1841.




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Elements of pathology and therapeutics being the outlines of a work, intended to ascertain the nature, causes, and most efficacious modes of prevention and cure, of the greater number of the diseases incidental to the human frame : illustrated by numerous

Bath : And sold by Underwood, London, 1825.




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An enquiry into the source from whence the symptoms of the scurvy and of putrid fevers, arise : and into the seat which those affections occupy in the animal oeconomy; with a view of ascertaining a more just idea of putrid diseases than has generally been

London : printed for J. Dodsley, 1782.




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Entoptics, with its uses in physiology and medicine / by James Jago.

London : J. Churchill, 1864.




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Epidemiology, or, The remote cause of epidemic diseases in the animal and in the vegetable creation ... Part 1 / by John Parkin.

London : J. & A. Churchill, 1873.




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Epilepsy : its symptoms, treatment, and relation to other chronic convulsive diseases / by J. Russell Reynolds.

London : J. Churchill, 1861.




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The Erasmus Wilson lectures on the pathology and diseases of the thyroid gland / by Walter Edmunds.

Edinburgh : Young J. Pentland, 1901.




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Eruptions of the face, head, and hands : with the latest improvements in the treatment of diseases of the skin / by T.H. Burgess.

London : H. Renshaw, 1849.




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Essai sur la leucorrhée et les causes diverses qui la produisent / par A.M. Bureaud Riofrey.

Londres : L’Auteur, 1834.




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Essai sur le typhus, ou sur les fièvres dites malignes, putrides, bilieuses, muqueuses, jaune, la peste. Exposition analytique et expérimentale de la nature des fièvres en général ... / par J.F. Hernandez.

Paris : chez Mequignon-Marvis, 1816.




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Florida Passes Anti-Semitism Bill for Public Schools

A bill prohibiting anti-Semitism in Florida's public schools and universities is going to Republican Gov. Ron DeSantis.




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Teachers Shortchanged On Bonuses in Idaho

Idaho lawmakers were upset to learn that nearly $17 million dedicated to giving teachers in leadership positions and assistants bonuses hasn't been distributed.




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Students' Song About KKK Raises Cautions for Teachers

A viral video of Dover, N.H., high school students singing a song about the Ku Klux Klan to the tune of "Jingle Bells" is causing outrage.




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Consultation with community: planning the next phases of the project

The Rediscovering Indigenous Languages project is entering its second phase, which will focus on community consultation




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Iowa Caucuses Offer Students a Laboratory for Civics Education

With their state’s caucuses the first official marker in the 2020 presidential contest, Iowa teenagers are in a unique position to observe and participate.




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The Iowa Caucuses: a Political Mess, but a Teaching Opportunity?

Primary season is now upon us. Here are three ideas for teaching in the wake of the Iowa caucus fallout.




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Iowa governor: K-12 schools won't resume classes this year




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Walz ends school year, but lets some businesses reopen




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Earthquake Scuttles Classes in Alaska, As California Students Return to School

While thousands of students in wildfire-ravaged Northern California resumed classes last week, thousands of others in Alaska stayed home after a 7.0 magnitude earthquake struck Nov. 30.




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Alaska Governor, a Career Educator, Proposes a Slash and Burn K-12 Budget

Gov. Mike Dunleavy, who spent his career as a teacher, principal and superintendent of a rural Alaska district wants to now cut more than a third of the state's K-12 spending.




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Alaska Gov., a Career Educator, Proposes Slash and Burn K-12 Budget

Alaska Gov. Mike Dunleavy, a Republican who was elected partly because of his experience as a public school educator, proposed a budget this year that would slash more than a quarter of the state's $1.6 billion education budget.




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Horses being ridden into the sea to bathe. Mezzotint by W. Ward, 1814, after G. Morland.

London (96, Gracechurch Street) : Published by R. Lambe, May 10th. 1814.




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Aeneas carrying his father Anchises on his shoulders as he, his son Ascanius and his wife Creusa flee from the sack of Troy. Engraving by R. Guidi after Agostino Carracci after F. Barocci.




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The personification of the art of painting, supported by Cardinal Girolamo Buonvisi, arrives on a triumphal car at Mount Helicon where she is greeted by the muses. Etching by P. Testa.

[Rome?]




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Babylon: Nebuchadnezzar praises the greatness of the city. Coloured etching, 17--.

Se vend a Augsbourg [Augsburg] : Au Negoce com(m)un de l'Academie Imperiale d'Empire des Arts libereaux avec privilege de Sa Majesté Impériale et avec defense ni d'en faire ni de vendre les copies, [between 1700 and 1799]




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Java: a Javanese man and woman, with houses behind. Etching by F. Garden, 1752.

[London] : [Richard Baldwin], [1752]




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In Illinois, New Budget Caps Raises and Limits Pensions for Teachers

The state's budget bill, which Republican Gov. Bruce Rauner signed into law this week, caps annual raises for end-of-career-teachers, lowering the pension they can receive.




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My glasses / by Chubby Kitten.




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Aminergic hypotheses of behavior : reality or cliché? / edited by Bruce Kenneth Bernard.

Rockville, Maryland : National Institute on Drug Abuse, 1975.




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Adolescent drug abuse : analyses of treatment research / editors, Elizabeth R. Rahdert, John Grabowski.

Rockville, Maryland : National Institute on Drug Abuse, 1988.




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Asymptotic properties of the maximum likelihood and cross validation estimators for transformed Gaussian processes

François Bachoc, José Betancourt, Reinhard Furrer, Thierry Klein.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1962--2008.

Abstract:
The asymptotic analysis of covariance parameter estimation of Gaussian processes has been subject to intensive investigation. However, this asymptotic analysis is very scarce for non-Gaussian processes. In this paper, we study a class of non-Gaussian processes obtained by regular non-linear transformations of Gaussian processes. We provide the increasing-domain asymptotic properties of the (Gaussian) maximum likelihood and cross validation estimators of the covariance parameters of a non-Gaussian process of this class. We show that these estimators are consistent and asymptotically normal, although they are defined as if the process was Gaussian. They do not need to model or estimate the non-linear transformation. Our results can thus be interpreted as a robustness of (Gaussian) maximum likelihood and cross validation towards non-Gaussianity. Our proofs rely on two technical results that are of independent interest for the increasing-domain asymptotic literature of spatial processes. First, we show that, under mild assumptions, coefficients of inverses of large covariance matrices decay at an inverse polynomial rate as a function of the corresponding observation location distances. Second, we provide a general central limit theorem for quadratic forms obtained from transformed Gaussian processes. Finally, our asymptotic results are illustrated by numerical simulations.




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Assessing prediction error at interpolation and extrapolation points

Assaf Rabinowicz, Saharon Rosset.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 272--301.

Abstract:
Common model selection criteria, such as $AIC$ and its variants, are based on in-sample prediction error estimators. However, in many applications involving predicting at interpolation and extrapolation points, in-sample error does not represent the relevant prediction error. In this paper new prediction error estimators, $tAI$ and $Loss(w_{t})$ are introduced. These estimators generalize previous error estimators, however are also applicable for assessing prediction error in cases involving interpolation and extrapolation. Based on these prediction error estimators, two model selection criteria with the same spirit as $AIC$ and Mallow’s $C_{p}$ are suggested. The advantages of our suggested methods are demonstrated in a simulation and a real data analysis of studies involving interpolation and extrapolation in linear mixed model and Gaussian process regression.




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A Bayesian approach to disease clustering using restricted Chinese restaurant processes

Claudia Wehrhahn, Samuel Leonard, Abel Rodriguez, Tatiana Xifara.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1449--1478.

Abstract:
Identifying disease clusters (areas with an unusually high incidence of a particular disease) is a common problem in epidemiology and public health. We describe a Bayesian nonparametric mixture model for disease clustering that constrains clusters to be made of adjacent areal units. This is achieved by modifying the exchangeable partition probability function associated with the Ewen’s sampling distribution. We call the resulting prior the Restricted Chinese Restaurant Process, as the associated full conditional distributions resemble those associated with the standard Chinese Restaurant Process. The model is illustrated using synthetic data sets and in an application to oral cancer mortality in Germany.




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Testing goodness of fit for point processes via topological data analysis

Christophe A. N. Biscio, Nicolas Chenavier, Christian Hirsch, Anne Marie Svane.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1024--1074.

Abstract:
We introduce tests for the goodness of fit of point patterns via methods from topological data analysis. More precisely, the persistent Betti numbers give rise to a bivariate functional summary statistic for observed point patterns that is asymptotically Gaussian in large observation windows. We analyze the power of tests derived from this statistic on simulated point patterns and compare its performance with global envelope tests. Finally, we apply the tests to a point pattern from an application context in neuroscience. As the main methodological contribution, we derive sufficient conditions for a functional central limit theorem on bounded persistent Betti numbers of point processes with exponential decay of correlations.




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Targeted Fused Ridge Estimation of Inverse Covariance Matrices from Multiple High-Dimensional Data Classes

We consider the problem of jointly estimating multiple inverse covariance matrices from high-dimensional data consisting of distinct classes. An $ell_2$-penalized maximum likelihood approach is employed. The suggested approach is flexible and generic, incorporating several other $ell_2$-penalized estimators as special cases. In addition, the approach allows specification of target matrices through which prior knowledge may be incorporated and which can stabilize the estimation procedure in high-dimensional settings. The result is a targeted fused ridge estimator that is of use when the precision matrices of the constituent classes are believed to chiefly share the same structure while potentially differing in a number of locations of interest. It has many applications in (multi)factorial study designs. We focus on the graphical interpretation of precision matrices with the proposed estimator then serving as a basis for integrative or meta-analytic Gaussian graphical modeling. Situations are considered in which the classes are defined by data sets and subtypes of diseases. The performance of the proposed estimator in the graphical modeling setting is assessed through extensive simulation experiments. Its practical usability is illustrated by the differential network modeling of 12 large-scale gene expression data sets of diffuse large B-cell lymphoma subtypes. The estimator and its related procedures are incorporated into the R-package rags2ridges.




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Learning with Fenchel-Young losses

Over the past decades, numerous loss functions have been been proposed for a variety of supervised learning tasks, including regression, classification, ranking, and more generally structured prediction. Understanding the core principles and theoretical properties underpinning these losses is key to choose the right loss for the right problem, as well as to create new losses which combine their strengths. In this paper, we introduce Fenchel-Young losses, a generic way to construct a convex loss function for a regularized prediction function. We provide an in-depth study of their properties in a very broad setting, covering all the aforementioned supervised learning tasks, and revealing new connections between sparsity, generalized entropies, and separation margins. We show that Fenchel-Young losses unify many well-known loss functions and allow to create useful new ones easily. Finally, we derive efficient predictive and training algorithms, making Fenchel-Young losses appealing both in theory and practice.




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Sparse and low-rank multivariate Hawkes processes

We consider the problem of unveiling the implicit network structure of node interactions (such as user interactions in a social network), based only on high-frequency timestamps. Our inference is based on the minimization of the least-squares loss associated with a multivariate Hawkes model, penalized by $ell_1$ and trace norm of the interaction tensor. We provide a first theoretical analysis for this problem, that includes sparsity and low-rank inducing penalizations. This result involves a new data-driven concentration inequality for matrix martingales in continuous time with observable variance, which is a result of independent interest and a broad range of possible applications since it extends to matrix martingales former results restricted to the scalar case. A consequence of our analysis is the construction of sharply tuned $ell_1$ and trace-norm penalizations, that leads to a data-driven scaling of the variability of information available for each users. Numerical experiments illustrate the significant improvements achieved by the use of such data-driven penalizations.




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Scalable Approximate MCMC Algorithms for the Horseshoe Prior

The horseshoe prior is frequently employed in Bayesian analysis of high-dimensional models, and has been shown to achieve minimax optimal risk properties when the truth is sparse. While optimization-based algorithms for the extremely popular Lasso and elastic net procedures can scale to dimension in the hundreds of thousands, algorithms for the horseshoe that use Markov chain Monte Carlo (MCMC) for computation are limited to problems an order of magnitude smaller. This is due to high computational cost per step and growth of the variance of time-averaging estimators as a function of dimension. We propose two new MCMC algorithms for computation in these models that have significantly improved performance compared to existing alternatives. One of the algorithms also approximates an expensive matrix product to give orders of magnitude speedup in high-dimensional applications. We prove guarantees for the accuracy of the approximate algorithm, and show that gradually decreasing the approximation error as the chain extends results in an exact algorithm. The scalability of the algorithm is illustrated in simulations with problem size as large as $N=5,000$ observations and $p=50,000$ predictors, and an application to a genome-wide association study with $N=2,267$ and $p=98,385$. The empirical results also show that the new algorithm yields estimates with lower mean squared error, intervals with better coverage, and elucidates features of the posterior that were often missed by previous algorithms in high dimensions, including bimodality of posterior marginals indicating uncertainty about which covariates belong in the model.




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Adaptive two-treatment three-period crossover design for normal responses

Uttam Bandyopadhyay, Shirsendu Mukherjee, Atanu Biswas.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 291--303.

Abstract:
In adaptive crossover design, our goal is to allocate more patients to a promising treatment sequence. The present work contains a very simple three period crossover design for two competing treatments where the allocation in period 3 is done on the basis of the data obtained from the first two periods. Assuming normality of response variables we use a reliability functional for the choice between two treatments. We calculate the allocation proportions and their standard errors corresponding to the possible treatment combinations. We also derive some asymptotic results and provide solutions on related inferential problems. Moreover, the proposed procedure is compared with a possible competitor. Finally, we use a data set to illustrate the applicability of the proposed design.




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Symmetrical and asymmetrical mixture autoregressive processes

Mohsen Maleki, Arezo Hajrajabi, Reinaldo B. Arellano-Valle.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 273--290.

Abstract:
In this paper, we study the finite mixtures of autoregressive processes assuming that the distribution of innovations (errors) belongs to the class of scale mixture of skew-normal (SMSN) distributions. The SMSN distributions allow a simultaneous modeling of the existence of outliers, heavy tails and asymmetries in the distribution of innovations. Therefore, a statistical methodology based on the SMSN family allows us to use a robust modeling on some non-linear time series with great flexibility, to accommodate skewness, heavy tails and heterogeneity simultaneously. The existence of convenient hierarchical representations of the SMSN distributions facilitates also the implementation of an ECME-type of algorithm to perform the likelihood inference in the considered model. Simulation studies and the application to a real data set are finally presented to illustrate the usefulness of the proposed model.




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Spatiotemporal point processes: regression, model specifications and future directions

Dani Gamerman.

Source: Brazilian Journal of Probability and Statistics, Volume 33, Number 4, 686--705.

Abstract:
Point processes are one of the most commonly encountered observation processes in Spatial Statistics. Model-based inference for them depends on the likelihood function. In the most standard setting of Poisson processes, the likelihood depends on the intensity function, and can not be computed analytically. A number of approximating techniques have been proposed to handle this difficulty. In this paper, we review recent work on exact solutions that solve this problem without resorting to approximations. The presentation concentrates more heavily on discrete time but also considers continuous time. The solutions are based on model specifications that impose smoothness constraints on the intensity function. We also review approaches to include a regression component and different ways to accommodate it while accounting for additional heterogeneity. Applications are provided to illustrate the results. Finally, we discuss possible extensions to account for discontinuities and/or jumps in the intensity function.