si

Biodegradable nanocomposite fibrous scaffold mediated local delivery of vancomycin for the treatment of MRSA infected experimental osteomyelitis

Biomater. Sci., 2020, 8,2653-2665
DOI: 10.1039/D0BM00140F, Paper
Amit G. Krishnan, Raja Biswas, Deepthy Menon, Manitha B. Nair
The study shows the development of a biodegradable bi-functional composite scaffold that can reduce bacterial infection, while promotes bone regeneration in osteomyelitis, without the need for revision surgery.
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si

Interfacing human induced pluripotent stem cell-derived neurons with designed nanowire arrays as a future platform for medical applications

Biomater. Sci., 2020, 8,2434-2446
DOI: 10.1039/D0BM00182A, Paper
Jann Harberts, Undine Haferkamp, Stefanie Haugg, Cornelius Fendler, Dennis Lam, Robert Zierold, Ole Pless, Robert H. Blick
Nanostructured substrates such as nanowire arrays form a powerful tool for building next-generation medical devices.
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si

A novel peptide targeting gastrin releasing peptide receptor for pancreatic neoplasm detection

Biomater. Sci., 2020, 8,2682-2693
DOI: 10.1039/D0BM00162G, Paper
Yuanbiao Tu, Ji Tao, Fang Wang, Peifei Liu, Zhihao Han, Zhaolun Li, Yi Ma, Yueqing Gu
The designed novel peptide GB-6 with targeted GRPR-binding possesses more favorable pharmacokinetic properties and metabolic stability, as well as superior tumor-targeting ability in pancreatic cancer models, relative to BBN7–14.
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si

An intelligent vancomycin release system for preventing surgical site infections of bone tissues

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00255K, Paper
Yuan Li, Guang Li, Xiaoling Sha, Litao Li, Kuo Zhang, Daohong Liu, Yanfei Hao, Xu Cui, Lei Wang, Hao Wang
An intelligent anti-bacterial system can be constructed on implants during surgery.
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si

A multifunctional metal-biopolymer coordinated double network hydrogel combined with multi-stimulus responsiveness, self-healing, shape memory and antibacterial properties

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00425A, Paper
Kun Yan, Feiyang Xu, Chunyu Wang, Yingying Li, Yuanli Chen, Xiufang Li, Zhentan Lu, Dong Wang
A universal, straightforward macroscale assembly technology has been presented for fabrication of polysaccharide-based multifunctional DN gels based on metal coordination chemistry.
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si

Surface engineering of titanium alloy using metal-polyphenol network coating with magnesium ions for improved osseointegration

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00566E, Paper
Sangmin Lee, Yun-Young Chang, Jinkyu Lee, Sajeesh Kumar Madhurakkat Perikamana, Eun Mi Kim, Yang-Hun Jung, Jeong-Ho Yun, Heungsoo Shin
Although titanium-based implants are widely used in orthopedic and dental clinics, improved osseointegration at the bone–implant interface is still required.
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si

A biomimetic orally targeted delivery of Bindarit for immunotherapy of atherosclerosis

Biomater. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0BM00418A, Paper
Luqi Yin, Cuiping Peng, Yue Tang, Yuchuan Yuan, Jiaxing Liu, Tingting Xiang, Feila Liu, Zhou Xing, Xiaohui Li
Monocyte chemoattractant protein-1 (MCP-1) plays an important role in the development of atherosclerosis. However, the application of bindarit (a specific synthetic inhibitor of MCP-1) in atherosclerosis has not been confirmed...
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Eco-friendly synthesis of glutathione-capped CdTe/CdSe/ZnSe core/double shell quantum dots: their cytotoxicity and genotoxicity effects on Chinese hamster ovary cells

Toxicol. Res., 2019, 8,868-874
DOI: 10.1039/C9TX00113A, Paper
Neo Mervyn Monaheng, Sundararajan Parani, Mary Gulumian, Oluwatobi Samuel Oluwafemi
In this work, we report green one-pot synthesis, cytotoxicity and genotoxicity of glutathione-capped CdTe/CdSe/ZnSe heterostructured quantum dots (QDs) using a label-free xCELLigence RTCA system as well as the Cytokinesis Blocked Micronucleus assay.
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si

Tin thiocarbonohydrazone complexes: synthesis, crystal structures and biological evaluation

Toxicol. Res., 2019, 8,862-867
DOI: 10.1039/C9TX00109C, Paper
Jin Wang, Yu-Ting Wang, Yan Fang, Yan-Li Lu, Ming-Xue Li
Three organotin thiocarbonohydrazone complexes have been synthesized, and growth inhibition assays indicated that complex 3 has the highest tumor cell selectivity.
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miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by targeting the VEGFA/14-3-3γ signal pathway

Toxicol. Res., 2019, 8,875-884
DOI: 10.1039/C9TX00100J, Paper
Xuan-Ying Chen, Wei-Lin Huang, Xiao-Ping Peng, Yan-Ni Lv, Jun-He Li, Jian-Ping Xiong
Bevacizumab (BVZ) is a widely investigated angiogenesis inhibitor in cancer patients. Although the anti-tumor effects has been verified, cardiotoxicity may be the most serious side-effect for BVZ.
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Kaempferol derivatives isolated from Lens culinaris Medik. reduce DNA damage induced by etoposide in peripheral blood mononuclear cells

Toxicol. Res., 2019, 8,896-907
DOI: 10.1039/C9TX00176J, Paper
Magdalena Kluska, Michał Juszczak, Daniel Wysokiński, Jerzy Żuchowski, Anna Stochmal, Katarzyna Woźniak
Bioactive compounds isolated from plants are considered to be attractive candidates for cancer therapy.
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si

Characteristic synergistic cytotoxic effects toward cells in graphene oxide dressing with cadmium and copper ions

Toxicol. Res., 2019, 8,908-917
DOI: 10.1039/C9TX00146H, Paper
Yiyang Dong, Yulin Chang, Haidi Gao, Victoria Arantza León Anchustegui, Qiang Yu, Haifang Wang, Jia-Hui Liu, Shihui Wang
Cadmium ions exerted synergistic toxic effects with graphene oxide on Hela cells.
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Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice

Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper
Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
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Lipoic acid antagonizes paraquat-induced vascular endothelial dysfunction by suppressing mitochondrial reactive oxidative stress

Toxicol. Res., 2019, 8,918-927
DOI: 10.1039/C9TX00186G, Paper
Li Pang, Ping Deng, Yi-dan Liang, Jing-yu Qian, Li-Chuan Wu, Ling-ling Yang, Zheng-ping Yu, Zhou Zhou
α-Lipoic acid antagonizes paraquat toxicity.
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Reply to the ‘Comment on “Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use”’ by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9T

Toxicol. Res., 2019, 8,1059-1059
DOI: 10.1039/C9TX00216B, Comment
Open Access
D. Nicholas Bateman, James W. Dear
Mullins et al. made a comment on our article (DOI: 10.1039/C9TX00002J) stating they noticed the omission of the one-bag, standard concentration protocol which is shared by several centers in North America when we discussed IV acetylcysteine protocols.
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Biogenic Aspergillus tubingensis silver nanoparticles’ in vitro effects on human umbilical vein endothelial cells, normal human fibroblasts, HEPG2, and Galleria mellonella

Toxicol. Res., 2019, 8,789-801
DOI: 10.1039/C9TX00091G, Paper
Cristiane Angélica Ottoni, Durvanei Augusto Maria, Priscila Jane Romano de Oliveira Gonçalves, Welington Luiz de Araújo, Ana Olívia de Souza
Biogenic silver nanoparticles are ecofriendly and offers valuable possibilities of applications in several industrial areas.
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Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis

Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper
Open Access
Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
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Effects of moderate red wine on cardiovascular risk factors in diabetics: a systematic review and meta-analysis of randomized controlled trials

Toxicol. Res., 2019, 8,979-987
DOI: 10.1039/C9TX00227H, Paper
Saavia Alice Naame, Decheng Li, Ruixue Huang
Diabetes mellitus is of major public health concerns; its incidence is continuously increasing.
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si

Astilbin attenuates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB pathway

Toxicol. Res., 2019, 8,1002-1008
DOI: 10.1039/C9TX00222G, Paper
Jing Li, Zhaowei Gu, Yue Liu, Yu Wang, Min Zhao
Ischemic stroke is the second most common cause of death worldwide and cerebral ischemia/reperfusion (I/R) injury also leads to serious tissue damage.
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si

Astaxanthin reduces perfluorooctanoic acid cytotoxicity in Saccharomyces cerevisiae

Toxicol. Res., 2019, 8,1009-1015
DOI: 10.1039/C9TX00215D, Paper
S. J. Sudharshan, Raghavendra Tirupathi, Madhu Dyavaiah
Perfluorooctanoic acid (PFA) has been identified as an environmental contaminant of high concern for human health.
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Phytochemicals protect L02 cells against hepatotoxicity induced by emodin via the Nrf2 signaling pathway

Toxicol. Res., 2019, 8,1028-1034
DOI: 10.1039/C9TX00220K, Paper
Yan Yan, Kang Wang, Xu Tang, Jun-feng Gao, Bin-yu Wen
Dihydromyricetin (DMY), hyperoside and silybin are phytochemicals that belong to a class called flavonoids, and they have been used in liver protection pharmaceutical preparations, but the specific mechanism of these chemicals is still unclarified.
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Benzoquinone alters the lipid homeostasis in Saccharomyces cerevisiae

Toxicol. Res., 2019, 8,1035-1041
DOI: 10.1039/C9TX00139E, Paper
Abhishek Raj, Vasanthi Nachiappan
BQ exposure inhibited cell growth, increased the ROS-mediated apoptosis, and altered the phospholipids that resulted in membrane proliferation.
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Cytotoxic effect of silica nanoparticles against hepatocellular carcinoma cells through necroptosis induction

Toxicol. Res., 2019, 8,1042-1049
DOI: 10.1039/C9TX00240E, Paper
Yuexiang Niu, Engong Tang, Qingan Zhang
Hepatocellular carcinoma (HCC) is a common cancer that affects people worldwide with high morbidity and mortality, and its resistance to current chemotherapeutic drugs is a serious concern.
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si

AIIB extends $500 mn loan to India to deal with coronavirus crisis

The bank's board of directors has approved a loan to India to strengthen the preparedness of the country's national health system




si

Amarinder Singh asks administration to ensure welfare of migrant workers

The chief minister asked the industry ministry to "aggressively" pursue the development of the four industrial parks already announced by the state government in the budget for this fiscal.




si

Vizag gas leak: NGT orders LG Polymers to deposit Rs 50 cr pending probe

NGT bench set up fact-finding committee, to be headed by former AP High Court judge




si

Lockdown period not to be counted for determining residency of NRIs: CBDT

There were apprehensions that this extended stay could lead to these individuals becoming Indian residents as per Section 6 of the Income Tax Act




si

FM to discuss credit flow to NBFCs, businesses with banks on Monday

The FM will take stock of the credit sanction and disbursement by the banks since March 1, 2020, and the Covid-19-related emergency credit lines opened by the lenders




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Sitharaman launches two exchanges to take on offshore currency market

The launch comes amid the world's most expansive coronavirus lockdown, which has crippled businesses and hurt trading volumes in the country's financial markets.




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Covid-19: Relief for NRIs, foreign visitors as tax residency rules eased

The government imposed a lockdown on March 24 and is yet to open up travel, including international flights.




si

Assam latest to go for labour reforms, plans raising work hours by 50%

Unlike other BJP-ruled states, it isn't doing away with most existing laws, but seeks to introduce fixed-term employment to facilitate direct hiring of contract labour by firms




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Probing permanent dipoles in CdSe nanoplatelets with transient electric birefringence

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR00884B, Paper
Ivan Dozov, Claire Goldmann, Patrick Davidson, Benjamin Abécassis
Transient electric birefringence experiments with colloidal suspensions of zinc-blende CdSe semiconducting nanoplatelets prove that these particles bear a large ground-state electric dipole despite the cubic structure of bulk zinc-blende CdSe.
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Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10245K, Paper
Open Access
Woranan Netkueakul, Daria Korejwo, Tobias Hammer, Savvina Chortarea, Patrick Rupper, Oliver Braun, Michel Calame, Barbara Rothen-Rutishauser, Tina Buerki-Thurnherr, Peter Wick, Jing Wang
We measured the cytotoxicity of pristine GRMs and the abraded particles from epoxy/GRM composites, which indicated low risks to consumers of such composites.
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RGD functionalized chitosan nanoparticle mediated targeted delivery of raloxifene selectively suppresses angiogenesis and tumor growth in breast cancer

Nanoscale, 2020, Advance Article
DOI: 10.1039/C9NR10673A, Paper
Amit S. Yadav, N. Naga Venkata Radharani, Mahadeo Gorain, Anuradha Bulbule, Dattatrya Shetti, Gaurab Roy, Thejus Baby, Gopal C. Kundu
Peptide functionalized pH sensitive raloxifene-chitosan nanoparticles with high biocompatibility synergistically inhibit tumor growth and angiogenesis in breast cancer.
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Efficient sub-15 nm cubic-phase core/shell upconversion nanoparticles as reporters for ensemble and single particle studies

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR02172E, Paper
Meiling Tan, Melissa-Jane Monks, Dingxin Huang, Yongjun Meng, Xuewen Chen, Ying Zhou, Shuang-Fang Lim, Christian Würth, Ute Resch-Genger, Guanying Chen
A set of sub-15 nm ytterbium-enriched α-NaYbF4:Er3+@CaF2 core/shell upconversion nanoparticles have been developed for both ensemble- and single particle-level imaging studies, presenting a high quantum yield of 0.77% at a low saturation power density of 110 W cm−2.
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si

Dual-sensitized Upconversion-assisted, Triple-band Absorbing Luminescent Solar Concentrators

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01008A, Paper
Sung Kyung Nam, Kiwon Kim, Ji-Hwan Kang, Jun Hyuk Moon
Luminescent solar concentrator-photovoltaic systems (LSC-PV) harvest solar light by using transparent photoluminescent plates, which is expected to be particularly useful for building-integrated PV applications. LSC panels that absorb multiple wavelength...
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Dy2@C79N: A New Member of Dimetalloazafullerenes with Strong Single Molecular Magnetism

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02519D, Paper
Yuanyuan Wang, Jin Xiong, Jie Su, Zi-Qi Hu, Fang Ma, Rong Sun, Xue-You Tan, Hao-Ling Sun, Bingwu Wang, Zujin Shi, Song Gao
Enhancing the exchange interaction between magnetic ions is a long-term target in molecular magnetism. Endohedral metallofullerenes (EMFs) provide a possibility for achieving such a goal by imprisoning multiple magnetic centers...
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A super stable assembled P nanowire with variant structural and magnetic/electronic properties via transition metal adsorption

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02176H, Paper
Sukai Wang, Jinxing Gu, Yinan Dong, Linwei Sai, Fengyu Li
By means of first-principles calculations, we systematically investigated the structure, stability, magnetic and electronic properties of one-dimensional P nanowire (1D-P10 NW) assembled by Pn subunits (n = 2, 8) and...
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Multi-praseodymium-and-tungsten bridging octameric tellurotungstate and its 2D honeycomb composite film for detecting estrogen

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01901A, Paper
Yan Zhang, Jun JIang, Yifan Liu, Pan Li, Yong Liu, Lijuan Chen, Junwei Zhao
Under coordination driving force of tungsten and rare-earth (RE) bridges, we synthesized a novel giant multi-tungsten-and-RE—bridging octameric tellurotungstate (TT) [H2N(CH3)2]16K8Na6H10[Pr8(H2O)20W16O48][B-α-TeW9O33]8·70H2O (1) in CH3CN-H2O mixed solvent. The cluster anion {[Pr8(H2O)20W16O48][B-α-TeW9O33]8}40– features...
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Wrinkle-induced highly conductive channels in graphene on SiO2/Si substrate

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR01406K, Paper
Ruisong Ma, Jiajun Ma, Jiahao Yan, Liangmei Wu, Wei Guo, Shuai Wang, Qing Huan, Lihong Bao, Sokrates T Pantelides, Hong-Jun Gao
Graphene wrinkle is a quasi-one-dimensional structure and can alter the intrinsic physical and chemical activity, modify the band structure and introduce transport anisotropy in graphene thin films. However, their quasi-one-dimensional...
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Plasma-assisted filling electron beam lithography for high throughput patterning of large area closed polygon nanostructures

Nanoscale, 2020, Advance Article
DOI: 10.1039/D0NR01032D, Paper
You Sin Tan, Hailong Liu, Qifeng Ruan, Hao Wang, Joel K. W. Yang
The PFEBL process allows enhancement of electron beam writing efficiency for patterning of closed polygon structures using a post-exposure plasma treatment.
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Mechanistic Insight in Site-selective and Anisotropic Etching of Prussian Blue Analogues toward Designable Complex Architectures for Efficient Energy Storage

Nanoscale, 2020, Accepted Manuscript
DOI: 10.1039/D0NR02241A, Paper
Hai Xu, Xi Zhao, Chenyang Yu, Yue Sun, Zengyu Hui, Ruicong Zhou, Jialu Xue, Henghan Dai, Yue Zhao, Lumin Wang, Yujiao Gong, Jin Yuan Zhou, Jianing An, Qiang Chen, Gengzhi Sun, Wei Huang
Engineering coordination compounds, e.g., prussian blue (PB) and its analogues (PBAs), with designable complex nanostructures via chemical etching holds great opportunities for improving energy storage performances by adjusting topological geometry,...
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A three-dimensional Cu nanobelt cathode for highly efficient electrocatalytic nitrate reduction

Nanoscale, 2020, 12,9385-9391
DOI: 10.1039/C9NR10743F, Paper
Xiaodan Wang, Mengqi Zhu, Guoshen Zeng, Xun Liu, Chihhsiang Fang, Chuanhao Li
A three-dimensional Cu nanobelt cathode was developed to efficiently catalyze the electrocatalytic nitrate reduction process.
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Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy

Nanoscale, 2020, 12,9392-9403
DOI: 10.1039/D0NR00563K, Paper
Yifei Wang, Ruiting Wang, Sixuan Wu, Jingyi An, Yan Liang, Lin Hou, Zhenzhong Zhang
Delivering the pten gene into tumor cells to reacquire PTEN functionality is considered to be an attractive method for cancer treatment.
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Ligand exchange on Au38(SR)24: substituent site effects of aromatic thiols

Nanoscale, 2020, 12,9423-9429
DOI: 10.1039/D0NR01430C, Paper
Yingwei Li, Rosalba Juarez-Mosqueda, Yongbo Song, Yuzhuo Zhang, Jinsong Chai, Giannis Mpourmpakis, Rongchao Jin
Ligand exchange on Au38(SR)24 with 21 different thiols reveals the substituent site effects of ligands on nanocluster transformation, and “anagostic” interactions are observed.
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Ionic liquid assisted preparation and modulation of the photoluminescence kinetics for highly efficient CsPbX3 nanocrystals with improved stability

Nanoscale, 2020, 12,9569-9580
DOI: 10.1039/D0NR00579G, Paper
Ting Chen, Yanqiao Xu, Zhixiang Xie, Weihui Jiang, Lianjun Wang, Wan Jiang
A facile approach was performed to synthesize CsPbBr3 NCs with the assistance of ionic liquid [Bmim]Br, which could modulate the surface property and enhace the stability of NCs effectively.
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Strong plasmon–exciton coupling between lithographically defined single metal nanoparticles and monolayer WSe2

Nanoscale, 2020, 12,9708-9716
DOI: 10.1039/D0NR01056A, Paper
Xiaohong Yan, Hong Wei
Strong coupling between monolayer WSe2 and lithographically defined single gold nanobowties is realized for the first time, and smaller nanobowties lead to larger coupling strength.
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Analysis of sparse molecular distributions in fibrous arrangements based on the distance to the first neighbor in single molecule localization microscopy

Nanoscale, 2020, 12,9495-9506
DOI: 10.1039/C9NR10805J, Paper
Alan M. Szalai, Lucía F. Lopez, Miguel Ángel Morales-Vásquez, Fernando D. Stefani, Pedro F. Aramendía
We introduce a robust and sensitive metric to characterize the underlying structure responsible for the molecular distribution, even at a very low labeling density.
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Facile synthesis of core–shell structured Si@graphene balls as a high-performance anode for lithium-ion batteries

Nanoscale, 2020, 12,9616-9627
DOI: 10.1039/D0NR01346C, Paper
Anif Jamaluddin, Bharath Umesh, Fuming Chen, Jeng-Kuei Chang, Ching-Yuan Su
Encapsulating silicon (Si) nanoparticles with graphene nanosheets in a microspherical structure is proposed to increase electrical conductivity and solve stability issues when using Si as an anode material in lithium-ion batteries (LIBs).
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A high-efficiency ammonia-responsive solar evaporator

Nanoscale, 2020, 12,9680-9687
DOI: 10.1039/D0NR00791A, Paper
Jingjing Xing, Jintao Tong, Ye Liu, Yutong Guo, Lanjian Zhuge, Dafeng Zhang, Ruomeng Duan, Bo Song, Yu Zhao, Bin Dong
We report a highly efficient solar evaporator based on the TiO2NP and PPyNP composite with ammonia responsiveness.
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