Ethereal photos of life’s building blocks, Earth’s toughest creature and a close-up of a gem win Olympus Global Image of the Year Life Science Light Microscopy Award regional prizes

Elisabeth Bik is on a mission to detect duplicate images in scientific papers, exposing either genuine mistakes or signs of fraud. But her work isn't always appreciated, she says

The first Biograph Vision PET/CT system (Siemens Healthineers) was installed at the University Medical Center Groningen. Improved performance of this system could allow for a reduction in activity administration or scan duration. This study evaluated the effects of reduced scan duration in oncologic ¹⁸F-FDG PET imaging on quantitative and subjective imaging parameters and its influence on clinical image interpretation. Methods: Patients referred for a clinical PET/CT scan were enrolled in this study, received a weight-based ¹⁸F-FDG injected activity, and underwent list-mode PET acquisition at 180 s per bed position (s/bp). Acquired PET data were reconstructed using the vendor-recommended clinical reconstruction protocol (hereafter referred to as "clinical"), using the clinical protocol with additional 2-mm gaussian filtering (hereafter referred to as "clinical+G2"), and—in conformance with European Association of Nuclear Medicine Research Ltd. (EARL) specifications—using different scan durations per bed position (180, 120, 60, 30, and 10 s). Reconstructed images were quantitatively assessed for comparison of SUVs and noise. In addition, clinically reconstructed images were qualitatively evaluated by 3 nuclear medicine physicians. Results: In total, 30 oncologic patients (22 men, 8 women; age: 48–88 y [range], 67 ± 9.6 y [mean ± SD]) received a single weight-based (3 MBq/kg) ¹⁸F-FDG injected activity (weight: 45–123 kg [range], 81 ± 15 kg [mean ± SD]; activity: 135–380 MBq [range], 241 ± 47.3 MBq [mean ± SD]). Significant differences in lesion SUV_max were found between the 180-s/bp images and the 30- and 10-s/bp images reconstructed using the clinical protocols, whereas no differences were found in lesion SUV_peak. EARL-compliant images did not show differences in lesion SUV_max or SUV_peak between scan durations. Quantitative parameters showed minimal deviation (~5%) in the 60-s/bp images. Therefore, further subjective image quality assessment was conducted using the 60-s/bp images. Qualitative assessment revealed the influence of personal preference on physicians’ willingness to adopt the 60-s/bp images in clinical practice. Although quantitative PET parameters differed minimally, an increase in noise was observed. Conclusion: With the Biograph Vision PET/CT system for oncologic ¹⁸F-FDG imaging, scan duration or activity administration could be reduced by a factor of 3 or more with the use of the clinical+G2 or the EARL-compliant reconstruction protocol.

Radiohybrid PSMA (rhPSMA) ligands, a new class of theranostic prostate-specific membrane antigen (PSMA)–targeting agents, feature fast ¹⁸F synthesis and utility for labeling with radiometals. Here, we assessed the biodistribution and image quality of ¹⁸F-rhPSMA-7 to determine the best imaging time point for patients with prostate cancer. Methods: In total, 202 prostate cancer patients who underwent a clinically indicated ¹⁸F-rhPSMA-7 PET/CT were retrospectively analyzed, and 12 groups based on the administered activity and uptake time of PET scanning were created: 3 administered activities (low, 222–296 MBq; moderate, 297–370 MBq; and high, 371–444 MBq) and 4 uptake time points (short, 50–70 min; intermediate, 71–90 min; long, 91–110 min; and extra long, ≥111 min). For quantitative analyses, SUV_mean and organ- or tumor-to-background ratio were determined for background, healthy organs, and 3 representative tumor lesions. Qualitative analyses assessed overall image quality, nonspecific blood-pool activity, and background uptake in bone or marrow using 3- or 4-point scales. Results: In quantitative analyses, SUV_mean showed a significant decrease in the blood pool and lungs and an increase in the kidneys, bladder, and bones as the uptake time increased. SUV_mean showed a trend to increase in the blood pool and bones as the administered activity increased. However, no significant differences were found in 377 tumor lesions with respect to the administered activity or uptake time. In qualitative analyses, the overall image quality was stable along with the uptake time, but the proportion rated to have good image quality decreased as the administered activity increased. All other qualitative image parameters showed no significant differences for the administered activities, but they showed significant trends with increasing uptake time: less nonspecific blood activity, more frequent background uptake in the bone marrow, and increased negative impact on clinical decision making. Conclusion: The biodistribution of ¹⁸F-rhPSMA-7 was similar to that of established PSMA ligands, and tumor uptake of ¹⁸F-rhPSMA-7 was stable across the administered activities and uptake times. An early imaging time point (50–70 min) is recommended for ¹⁸F-rhPSMA-7 PET/CT to achieve the highest overall image quality.

An AI search engine takes one-tenth of a second to search more than 2 billion satellite images, identifying natural or built features that look alike, such as forests or military bases

An image-editing program designed by researchers at Abode uses AI to let you quickly transform the shape of objects in images and change the lighting

Don't analyse them too closely, they didn't have HD in the 1970s.

Only the best images are used to create a mosaic of the entire planet, resulting in a super-crisp, high-definition view.

A group of astronomers has called for legal action to stop the launch of thousands of satellites designed by companies like SpaceX and OneWeb to beam high-speed internet around the world

This week we have our PAX Prime wrapup! Of course, while we were out at PAX Sony and Nintendo decide to announce a billion games...

Researchers have used synchrotron light to study what happens to the nerves in diabetes. The technique shows the 3D-structure of nerve fibers in very high resolution.

You can order a print at thefelixproject.org/peterblake

These stunning images show some of the mesmerising sights captured by the Hubble Telescope during its 30 years of observing space.

An aerial photo of ocean sands in the Bahamas has been voted the NASA Earth Observatory's all-time best image.

The Hawaii-based Gemini telescope produces a super-sharp picture of the gas giant in the infrared.

Nasa and the European Space Agency have shared new images of Comet Atlas as it flies towards Earth.

Pictures are some of the sharpest infrared images of Jupiter ever taken from the Earth

The overall winner will be announced in June

Tourist numbers have dwindled across Asia as coronavirus grounds travellers

Countries across Europe are gradually easing lockdown measures

Mohamed Salah's performance at the 2018 World Cup was negatively influenced by his row with the Egyptian Football Association (EFA), a former member of the organisation has claimed.

Guardian picture editor Fiona Shields explains why we are going to be using fewer polar bears and more people to illustrate our coverage of the climate emergency

• Support Guardian journalism today, by making a one-off or recurring contribution, or subscribing

At the Guardian we want to ensure that the images we publish accurately and appropriately convey the climate crisis that we face. Following discussions among editors about how we could change the language we use in our coverage of environmental issues, our attention then turned to images. We have been working across the organisation to better understand how we aim to visually communicate the impact the climate emergency is having across the world.

Related: The Guardian's climate pledge 2019

Investigations will begin into how a number of dams in drought-ravaged parts of NSW came to be filled during a ban on pumping water along parts of the Murray-Darling earlier this year.

Computerized tomography (CT) is one of the most effective medical tests for analysing the effects of many illnesses, including COVID-19. An international team has developed a new method that improves the quality of the images obtained from CT scans. The algorithm, tested on simulated data, enables them to distinguish different body's tissue types better and opens the door to lowering the doses of radiation to which patients are exposed during this type of test.

Here are the stories behind the most amazing images in the world of science this week. A recap of the coolest photos featured on Live Science.

We just shouldn’t be commenting on Adele’s body at all, activists say.

Las Vegas est presque aussi vide que le désert qui la cerne.

Michael Wayne Sulfridge, a resident of Union Grove, Ala., and former vice president of corporate finance at Image Entry, Inc. (Image Entry), pleaded guilty today to fraud and tax evasion charges stemming from the company’s 2001 acquisition by Sourcecorp, Inc. (Sourcecorp).

According to an indictment dated June 24, 2010, and unsealed today, James Dale Brown, 27, is alleged to have used the Internet social networking website Facebook to communicate with a minor female identified as Jane Doe. 

Yokogawa Electric Corporation (TOKYO: 6841) announces that on March 20, 2020, it completed the acquisition of all shares in Denmark-based Grazper Technologies ApS (Grazper), as mutually agreed. Grazper has developed advanced artificial intelligence (AI) technologies for analyzing images, and Yokogawa aims to leverage these technologies within its various existing businesses and to develop new industrial AI solutions.

Check out this year's winners of the Art of Neuroscience competition

TL;DR: Check out the Codepen. Also note that after publishing, I found that there are much nicer, stable solutions that preserve perfect aspect ratio if needed (see react-photo-gallery & Justified Gallery). I was on a hunt for a special type of masonry layout for an image gallery today. It needed to fulfill the following requirements: […]

The post A 'perfect' row-based image masonry appeared first on Paul Bakaus' blog.

Force India has released the first image of its long-awaited 2015 car, the VJM08

After a storm hit Tennessee last Sunday and Nashville saw record-shattering rainfall, the Cumberland River swelled to overflowing and the city experienced an epic flood. As soon as it was safe, residents were out

Building new roads has been a major contributor to the city's unsustainable growth, newly released Landsat photos show, but more of the same appears to be on the horizon.

Since the Viet Nam war, Canadians (and some Americans) have been sewing Canadian flag patches on their backpacks when they travel to distinguish themselves from their neighbours. But they will be ripping them off soon, as the country becomes an

The Echmiadzin Cathedral complex in Armenia is one of 12 spiritual destinations that are becoming more sustainable.

An interesting step towards eco-friendly spiritual travel: The Alliance of Regions and Conservation, working with WWF, is about to launch the Green Pilgrimage Network. The program, to formally kick off at an event in

A shark's fin is like its fingerprint, with each animal having its own unique patterns and scars.

In an homage to influential images of Earth taken from outer space, this art installation takes it up a notch by livestreaming views of Earth in real-time, prompting us to contemplate the bigger picture.

Take a thermographic tour of my house to see why.

Transforma Tu Hogar para este Verano