up Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00673A, Review ArticleJuhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong JunPotential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
up S-MGBs bearing amidine tail groups are potent, selective antiplasmodial agents By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00619D, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Marina Perieteanu, Tayner Rodriguez Garzon, Leah M. C. McGee, Abedawn I. Khalaf, Colin J. Suckling, Rebecca Beveridge, Vicky M. Avery, Fraser J. Scott25 S-MGBs, including those bearing an amidine tail group, were investigated for their antiplasmodial, in vitro activity against 3D7 and Dd2 strains of P. falciparum. Several potent, and selective, hit compounds were identified.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
up Synthesis of cationic N-acylated thiazolidine for selective activity against Gram-positive bacteria and evaluation of N-acylation's role in membrane-disrupting activity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00626G, Research ArticleAleena Pious, Vignesh Venkatasubramanian, Dharshini Karnan Singaravelu, Subburethinam Ramesh, Fuad Ameen, Anbazhagan VeerappanLipidation modulates the Gram-selective antibacterial activity of QPyNATh.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
up TNSTC Kumbakonam Division mops up ₹17.13 crore in four days By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:59:26 +0530 Full Article Tiruchirapalli
up Pumping stations to be set up in eight low-lying areas in Tiruchi to prevent inundation By www.thehindu.com Published On :: Wed, 06 Nov 2024 19:30:58 +0530 Full Article Tiruchirapalli
up Ernakulam Express to stop at Muthupettai during Kandhoori festival By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:51:18 +0530 Full Article Tiruchirapalli
up Bids invited for setting up International Dugong Conservation Centre at Manora By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:03:19 +0530 The proposed centre, to be set up at an estimate of ₹41 crore, is being established to conserve endangered Dugong species and its habitat in the Palk Bay Full Article Tiruchirapalli
up Small-scale handloom park to come up at Sengunthapuram By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:09:38 +0530 Ministers R. Gandhi and S.S. Sivashankar inspect the 13,205 sq. ft. site belonging to the Tamil Nadu Cotton Corporation at Sengunthapuram Full Article Tiruchirapalli
up Uppiliyapuram, gateway to scenic Pachamalai, lacks bus stand with passengers left to fight the elements By www.thehindu.com Published On :: Fri, 08 Nov 2024 19:20:03 +0530 Buses stop at a busy junction making it difficult for commuters as well as local businessmen; a site is yet to be identified for the bus stand Full Article Tiruchirapalli
up EPS’s dream of AIADMK staging a comeback in 2026 election will not materialise: Law Minister Regupathy By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:25:59 +0530 Full Article Tiruchirapalli
up Two doctors posted at Uppiliyapuram UPHC By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:29:46 +0530 Full Article Tiruchirapalli
up Library to hold Group II-A Mains, Group IV TNPSC model test By www.thehindu.com Published On :: Sat, 09 Nov 2024 17:59:22 +0530 Full Article Tiruchirapalli
up Art and literary contests lined up for District Central Library’s National Library Week By www.thehindu.com Published On :: Sat, 09 Nov 2024 18:07:57 +0530 Full Article Tiruchirapalli
up 542: Breaking Up with CSS-in-JS, Mastodon, and Stories on the Web By shoptalkshow.com Published On :: Mon, 21 Nov 2022 08:00:51 +0000 We're talking CSS-in-JS, Token CSS, Matuzo being suspended from Twitter, trying out Mastodon, testing out stable diffusion, stories on the web, and Jake Albaugh's new social network. Full Article All Episodes CSS mastodon stories Twitter
up 568: Display Contents, Passkeys Follow Up, Yellow Fade Technique, and TOTK Talk By shoptalkshow.com Published On :: Mon, 05 Jun 2023 19:53:09 +0000 Macho Man Randy Standards stops by for a quick chat, Passkeys follow up, discussing the safety of Display: contents, the yellow fade technique, how hot CSS is right now (so hot), and a check in on how everyone's doing with Tears of the Kingdom. Full Article All Episodes Astro botw passkeys totk yellow fade
up 578: Customer Support, P3 Color, Dave on Productivity, and Mobile vs Desktop By shoptalkshow.com Published On :: Mon, 14 Aug 2023 07:24:25 +0000 Is Apple's Numbers amazing or the worst? Customer support at various levels of software, Figma and P3 color, imagining a colorspace property in CSS, what's Dave doing for productivity, how has offloading CSS Tricks affected Chris, and should we build different websites for mobile vs desktop? Full Article All Episodes css tricks p3 Productivity Tools
up 610: TypeScript in 2024, Signals, Productivity Sniped, and Follow Up By shoptalkshow.com Published On :: Mon, 08 Apr 2024 08:38:19 +0000 Dave's about to be eclipsed, the state of TypeScript in 2024, signals stage zero proposal, corrections on accessibility in frameworks (thanks!), web apps for better collaborative writing, getting productivity sniped, the problem with email may be you, indieweb follow up, and ultimate guitar tab apps. Full Article All Episodes eclipse Email signals typescript
up 611: React! TypeScript! Jobification! Drupal! By shoptalkshow.com Published On :: Mon, 15 Apr 2024 08:30:37 +0000 Dave & Chris and thoughts on career advice that worked 3 years ago but isn't as helpful now, marking tests with ChatGPT, is taking a Drupal job in 2024 a good idea, Chris got #gear sniped, P3 color follow up, the confusing File System APIs, and where did all the lightboxes go? Full Article All Episodes Career Advice Drupal File System API p3
up 621: Setting Up Prettier and Linting, Comparing Colors, and Accessibility Overlays By shoptalkshow.com Published On :: Mon, 24 Jun 2024 08:05:22 +0000 We've got follow up on Cloudflare and Cara from last episode, a question about setting up Prettier and auto linting, a cool tool from a listener on comparing colors, a question about using tooling like Craft or more user friendly apps like Webflow when working with clients, and our takes on accessibility overlays. Full Article All Episodes Accessibility prettier webflow
up 622: Website Rendering, Updating Software, and Edge Gets Faster By shoptalkshow.com Published On :: Mon, 01 Jul 2024 08:26:04 +0000 We're talking website rendering, server side rendering, Astro's server islands, perf hits for navigation elements, updating software because the docs aren't available for older versions, and a new Microsoft Edge was released. Full Article All Episodes microsoft edge rendering server islands
up 630: Frostapalooza Recap, Follow Up, and Messy Codebases By shoptalkshow.com Published On :: Mon, 26 Aug 2024 08:22:05 +0000 Chris has a birthday today 🎉, we recap our Frostapalooza experience celebrating Brad Frost's birthday, do all codebases become a mess, Mermaid, TLDraw, and Figjam thoughts, making tiny games, where's the follow up in web and world news, and what's the current state of CMS' on the web? Full Article All Episodes birthday CMS drawing Wordpress
up 641: Passkey Usage, Writing Code with a Bot, and What’s Up With Java? By shoptalkshow.com Published On :: Mon, 11 Nov 2024 10:03:26 +0000 We've got a few leftovers from Halloween to process, what's been happening with Passkeys in late 2024, have you tried to write HTML faster than a bot can suggest it to you, CSS anchor positioning and popover polyfills, scroll driven animation thoughts, CSS nesting, and what's the reason for Java? Full Article All Episodes CSS Nesting Halloween Java passkeys Scroll Driven Animation
up Setting up shop in Chennai By www.thehindu.com Published On :: Fri, 04 Sep 2015 16:45:56 +0530 As businesses head to the city, the lack of large format office spaces is pushing them towards peripheral locations. Full Article Property Plus
up The pros and cons of spouses teaming up as co-founders By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 20:40:00 +0530 How do married co-founders navigate the personal and professional ties at work Full Article Emerging Entrepreneurs
up Startups join the party with craft mixers By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 20:56:00 +0530 How non-alcoholic mixers, handcrafted by small players, are edging out sugary soft drinks, sodas in cocktail glasses Full Article Emerging Entrepreneurs
up How ‘priority sector’ status can rev up Jan Dhan banking By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 21:31:00 +0530 How regulation can nudge private banks to promote financial inclusion Full Article Current Account
up Superlative Class By www.thehindubusinessline.com Published On :: Sat, 05 Oct 2024 08:33:00 +0530 The EQS SUV reinvigorates Mercedes-Benz’s game in the all-electric segment Full Article Auto focus
up Cargo companies upsize for new business By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 19:43:00 +0530 Booming demand for ecommerce delivery spurs freight handlers to open more centres, digitise for efficiency Full Article Logistics
up Bengaluru startup develops new tech for battery recycling, begins production By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 18:13:56 +0530 Li-ion battery recycler Metastable Materials launches commercial ops Full Article Clean Tech
up Keeping track of Scope-3 emissions from supply chains By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 18:58:37 +0530 Gurgaon-based startup OnlyGood FutureTech helps companies measure emissions generated by supply partners Full Article Clean Tech
up Delhi L-G lied in Supreme Court about tree felling: Bharadwaj By www.thehindu.com Published On :: Sat, 09 Nov 2024 00:39:15 +0530 Full Article Delhi
up Never asked people to pick up weapons: Tahir Hussain to court By www.thehindu.com Published On :: Sat, 09 Nov 2024 00:43:34 +0530 Full Article Delhi
up Congress gears up for Delhi poll battle with month-long ‘Nyay Yatra’ By www.thehindu.com Published On :: Sat, 09 Nov 2024 01:07:34 +0530 Maken, Sukhu flag off foot march; Kharge, Rahul expected to join at different junctures; yatra scheduled to end on Dec. 4; people won’t forget Cong.’s tie-up with AAP in Lok Sabha election: BJP Full Article Delhi
up Three juveniles held for murder in Delhi; political row erupts over city’s crime rate By www.thehindu.com Published On :: Sun, 10 Nov 2024 00:31:14 +0530 Full Article Delhi
up Security upped outside Canadian High Commission due to protest against temple attack By www.thehindu.com Published On :: Sun, 10 Nov 2024 16:13:43 +0530 The Hindu Sikh Global Forum members are marching towards the High Commission in the Chanakyapuri area Full Article Delhi
up The K7RA Solar Update By www.arrl.org Published On :: Fri, 25 Oct 2024 10:57:00 -0500 Key solar indicators were lower this week, with average daily solarflux down from 194.3 to 170.5 and average daily sunspot numbersdeclining from 129.3 to 127.7.On October 22, Spaceweather.com reported:"THE SUN IS TAKING A QUICK BREAK: Solar Max is hard work. Just askthe Sun. After flaring almost without pause for the past 10 months,the Sun is taking a quick break. Solar activity has been low fo... Full Article
up ARRL VEC Services Update During Systems Disruption By www.arrl.org Published On :: Wed, 30 Oct 2024 14:43:00 -0500 Updated 10/30/2024ARRL previously reported that we are responding to a serious incident involving access to our network and headquarters-based systems. Several services have been affected, including those administered by the ARRL Volunteer Examiner Coordinator (ARRL VEC).Exam Registrations and Materials. ARRL Volunteer Examiners (VEs) should continue to submit exam registrations and material re... Full Article
up The K7RA Solar Update By www.arrl.org Published On :: Fri, 01 Nov 2024 12:44:00 -0500 Solar activity increased this week. Average daily sunspot numberwent from 127.7 to 197.4 and average solar flux from 170.5 to 240.2.Predicted solar flux is 270 on November 1-2, 265 and 260 on November3-4, 250 on November 5-7, 214, 195 and 182 on November 8-10, 172,168, 174 and 165 on November 11-14, and 162 on November 15-16.Predicted planetary A index is 5, 8, 15, and 10 on November 1-4, 5on N... Full Article
up Hurricane Rafael - Storm Updates By www.arrl.org Published On :: Tue, 05 Nov 2024 11:00:00 -0600 Tuesday, November 5, 2024, 11:00 AM Eastern Update:The following information is from the Hurricane Watch Net:The Hurricane Watch Net will be activated today, Tuesday, as planned, with one minor update. After further review of the timing of the storm and the distance from land, we need to modify our plans. All will remain the same with the exception that we will now operate overnightActivation P... Full Article
up Building up an Arsenal By www.thehindubusinessline.com Published On :: Sun, 27 Dec 2020 21:23:23 +0530 The autobiography of a coach who revolutionised English football Full Article Books
up Book Review: Demystifying Leadership: Unveiling the Mahabharata Code by Asha Kaul and Vishal Gupta By www.thehindubusinessline.com Published On :: Wed, 02 Feb 2022 17:42:46 +0530 The Mahabharata shows that leaders need to navigate moral codes that are as complex, varied, and subtle as the situations in which they find themselves Full Article Book Reviews
up Start-up Compass: How Iconic Entrepreneurs got it Right By www.thehindubusinessline.com Published On :: Mon, 08 Aug 2022 20:25:04 +0530 A relevant book for those about to embark on their entrepreneurial journey, or can serve as a useful resource for those who like to track the start-up ecosystem Full Article Book Reviews
up My Farm, a farm-to-table set-up in Visakhapatnam, is an example of responsible farming By www.thehindu.com Published On :: Fri, 13 Oct 2023 17:21:18 +0530 Locally-grown vegetables find their way to My Farm, a farm-to-table set-up near Visakhapatnam, that adopts permaculture to promote sustainability as a way of life Full Article Agriculture
up Paddy varieties with protein, zinc content get thumbs up in Odisha’s tribal pocket By www.thehindu.com Published On :: Wed, 08 Nov 2023 11:37:33 +0530 Paddy varieties have high protein (10.1%) and moderately high level of zinc (20 ppm) content Full Article Other States
up Centre to provide 15,000 women self help groups with drones that can be rented out for agricultural purposes By www.thehindu.com Published On :: Wed, 29 Nov 2023 17:14:01 +0530 The scheme will help in infusing advanced technology in agriculture for improved efficiency, enhance crop yield and reduced cost of operation for the benefit of farmers Full Article Agri-Business
up Over ₹13 crore funds needed to support farmers in drought-affected areas of Nellore, says Collector By www.thehindu.com Published On :: Wed, 19 Jun 2024 20:07:59 +0530 Ten in the district have been declared as ‘drought mandals’ by the NDMA; over 50% of crop was lost in Sitaramapuram while 30-40% of crops were lost in the remaining nine mandals Full Article Andhra Pradesh
up Paddy MSP up 5.35% to ₹2,300 per quintal as Cabinet clears MSP hikes for 14 kharif crops By www.thehindu.com Published On :: Wed, 19 Jun 2024 20:17:45 +0530 MSPs for bajra, arhar dal, maize offer highest margins above production costs; Cabinet nod for Varanasi airport expansion, new Maharashtra port, wind energy projects in Gujarat and T.N., forensic infrastructure development Full Article India
up ‘Dairy dilemma’ engulfs women farmers in CM Chandrababu Naidu’s constituency Kuppam with sudden fall in milk price By www.thehindu.com Published On :: Mon, 01 Jul 2024 12:49:04 +0530 Recently, the dairy industry has experienced a decrease of ₹5 per liter in the milk price, causing concern among the predominantly women farmers involved in the sector. Full Article Andhra Pradesh
up Cabinet clears new scheme to supply virus-free planting material By www.thehindu.com Published On :: Sat, 10 Aug 2024 01:58:34 +0530 It will cover all farmers, regardless of their landholding size or socioeconomic status: Ministry Full Article India
up Taking roots in Tirupati, ‘Konark’ set to reach the kitchens of Odisha and Bengal By www.thehindu.com Published On :: Thu, 22 Aug 2024 11:38:21 +0530 Full Article Agriculture