So-called challenge trials are common in vaccine development, but only for viruses which have treatments. It comes as scientists around the world race to find a Covid cure - including two in the UK.

The end of the year is a time for reflection, looking back at the great and the good of the sporting world and those moments that have shown the best of 2019. We don't care about that, though, do we?

SARAH VINE: This is not a generation of doddery, grey-haired retirees, content to potter away their pensions in the back garden: These are people living life to the full. In many cases, their best life.

Boditech Med, based in Chuncheon, South Korea, is now manufacturing thousands of its iChroma COVID-19 antibody kits, which it claims are 96 per cent reliable.

The 30-year-old singer beamed while walking the red carpet with his five-year-old daughter Royalty on Sunday at the Grammy Awards in Los Angeles.

She performed at last month's Grammy Awards, where she was nominated for Best Pop Duo/Group Performance with her heartthrob boyfriend. 

Love Island Australia host Sophie Monk has defended the show amid talk of the toll starring on the show plays on the mental health of Islanders. 

Scientists led by the Massachusetts Institute of Technology found students who practised mindfulness reported less stress and negative emotions such as anger.

It takes a special someone to be compared to Angelina Jolie but Australian-born Natassia Halabi was told she was a 'Middle Eastern' version by her acting school classmates.

Angelina Jolie is using her own family medical history and experiences to shed light on advancements in cancer research, treatment and women's health and rights worldwide.

Angelina Jolie kept a cheerful smile on her face when she was seen grocery shopping with her daughter Vivienne, 11, in Los Angeles on Saturday.

One of Scotland's largest hospitality companies, the G1 Group, has stopped plans to dismiss its newest staff members, after the UK Government announced a job retention scheme.

Actor Lincoln Lewis has spoken out about the ongoing lack of discussion about mental health between Australian men, while opening up about his own crippling struggles. 

Former England Under-21 striker Marvin Sordell has described football as 'a beautiful game with an ugly persona' after citing his mental wellbeing as a big factor behind his decision to retire aged 28.

EXCLUSIVE BY MATT HUGHES: Sportsmail has learned that a proposal to bring in fixed sporting sanctions for missed games will be tabled as part of a wider discussion.

The League One side were given a five-point deduction, suspended for 18 months after they failed to fulfil some of their matches, as well as being handed a fine, but that has been called lenient.

Jerome Boateng's year in the Premier League between 2010 and 2011 was one to forget. He failed to earn a first XI place at Manchester City and was often played out of position at right back.

Everton manager Carlo Ancelotti revealed that Liverpool boss Jurgen Klopp believed playing Atletico Madrid in the Champions League in front of a full stadium was 'criminal'.

Liverpool council's director of public health has suggested the rise in coronavirus cases in the city may be influenced by the decision to allow the Reds' match against Atletico to take place.

Michael Bloomberg has officially announced he is running for president, bringing the Democratic primary field back up to 19 candidates.

ASK THE GP: My hair has been falling out since I had a pacemaker fitted three years ago. I was taking bisoprolol tablets, which I know can cause hair loss, but changing to a different medicine hasn't helped.

DR MARTIN SCURR: Barbara Connor, from South-East London, has a condition called claudication, which causes her problems in her legs.

ASK THE GP: For four months I have been suffering from an itchy scalp. There are no visible blemishes, but it is very irritating. The chemist suggested using a special shampoo. I am 79.

ASK THE GP: DR MARTIN SCURR: Oestrogen deficiency reduces collagen in the skin. These changes in menopause can cause excessive dryness and widespread itching.

The Daily Mail's resident doctor Martin Scurr answers your health concerns in his weekly column.

The Daily Mail's resident doctor Martin Scurr answers your health concerns in his column. This week a reader asks if the ringing in their ears is connected to them clenching their teeth.

Seborrhoeic dermatitis is a skin condition in which the scalp becomes red, itchy and flaky. It's very common - occurring in around one in 25 people. It can affect any area of oily skin.

Dry eye disease occurs when the mechanism that maintains a stable 'tear film' (watery fluid) across the surface of the eye is disturbed. Around 5 per cent of the population is affected.

DR MARTIN SCURR: Any persistent problem can be terribly frustrating but it is not the Barrett's oesophagus (pictured) that is causing your symptoms.

The Strictly Come Dancing professional, 38, insists she does her best to maintain a full, active lifestyle while remaining in lockdown with her new partner.

On a Friday night it's more common to be sipping a vodka cocktail than to be applying one to your hair.

Celebrities such as Madonna and Demi Moore guzzle coconut water by the gallon while cosmetic companies are also promoting its benefits.

Swimwear brand Summersalt has teamed up with five empowering females, including DailyMailTV's Alicia Quarles, to design confidence boosting swimsuit line.

IAN LADYMAN: Barely a month into football's current state of inertia and the head of FIFA has arrived with a basketful of meaningless platitudes to make us all feel better. 'Health must come better.'

Join Sportsmail's ANTHONY HAY with all the live action from the 7pm (BST) kick-off, with our reporters providing all the updates from Moscow.

The smog has blown over from a huge fire at Gospers Mountain in the Hawkesbury region. The Rural Fire Service is controlling the fire, which covers more than 160,000 hectares.

The 31-year-old woman was 38 weeks pregnant when she was set upon by a stranger while with friends at Bay Vista cafe on Church Street, Parramatta.

Fake social media posts are claiming coronavirus is spreading in several Sydney suburbs, and is even found in Lipton ice tea.

Reading have come from 2-0 down to defeat Championship rivals Cardiff City on penalties to progress to the fifth round of the FA Cup.

MATT BARLOW AT THE TOTTENHAM HOTSPUR STADIUM: Jose Mourinho was hired at great expense to win trophies, to end the long wait for Tottenham. Mourinho fixed his sights on the FA Cup.

Tim Krul had Spurs' penalty takers and the directions they would shoot listed on his water bottle ahead of Norwich's shock win on spot kicks in the FA Cup on Wednesday night.

Norwich goalkeeper Tim Krul saved penalties from Troy Parrott and Gedson Fernandes as Tuesday's fifth round tie at White Hart Lane was settled in a shoot-out after a 1-1 draw.

The world's richest people grew even richer in 2013, adding $524 billion to their collective net worth, with Bill Gates adding $15.8billion to his net worth.

COMMENT - JEFF POWELL: After more than 130 seasons of playing through rain, snow, ice and mud, our most over-paid and molly-coddled stars are getting a mid-winter break.

She's about to mark history as the first openly gay female superhero.

Sebastian Polter's 90th-minute penalty gave Union Berlin a 1-0 win over Hertha Berlin in the German capital's first Bundesliga derby featuring teams from either side of the formerly divided city.

PETE JENSON IN OSLO: Bournemouth's Joshua King won a point for Norway against Spain scoring a penalty against Kepa Arrizabalga after the Chelsea keeper had given away the spot-kick.

Spain midfielder Ceballos fouled Olsson and was subsequently shown a yellow card as Spain trailed in the match.

Sweden striker Alexander Isak was subjected to racist abuse by Romania fans during his side's 2-0 win. The game was stopped by the referee as the first step of UEFA's protocol.

The singer, 31, was one of the stars set to perform at the service on Monday alongside fellow hitmaker Craig David.