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Africa: Smallpox Eradication 'Greatest Public Health Triumph' - WHO Director-General Tedros

[WHO] Geneva -Good morning, good afternoon and good evening.




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Zimbabwe: Registrar-General Gets $10 000 Bail

[The Herald] Registrar-General Clement Masango yesterday denied any wrongdoing during his bail application before Harare regional magistrate Mrs Bianca Makwande.




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US general says coalition continuing fight against ISIS amid the pandemic


The pandemic has led to a series of changes, including the separation of US and coalition forces from locals.




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Employee from General Financial Directorate suspected in CZK 10 million bribe

Prague Daily Monitor

Police from the National Center Against Organized Crime suspect an employee from the General Financial Directorate of agreeing to a ten million crown bribe, five million of which he had personally taken possession of. The spokesperson for the General Financial Directorate Zuzana Masatova said "the employee has been removed from service."

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Pakistan sincerely supports Afghan peace process: General Qamar Javed Bajwa

RAWALPINDI: US Special Representative for Afghan Reconciliation Zalmay Khalilzad Friday called on Chief of Army Staff General Qamar Javed Bajwa here on Friday.During the meeting, issues of mutual interest and overall regional security situation, including Afghan reconciliation process, came under...




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dsPIC33CK64MC105 General Purpose Plug-In Module (PIM) Information Sheet

dsPIC33CK64MC105 General Purpose Plug-In Module (PIM) Information Sheet




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Fiji general cites need to ‘stifle criticism’ in the fight against the COVID-19 pandemic

"The COVID-19 pandemic is not an excuse for human rights violations. Excessive force and brutality are unacceptable from any of our enforcement or security forces."




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Intern - Office of the Director General, EARD - 2002

ADB has a vacancy for the position of Intern - Office of the Director General, EARD - 2002 in the East Asia Department. The deadline for submitting applications is on 15 September 2019.




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Director General

ADB has a vacancy for the position of Director General in the Private Sector Operations Department. The deadline for submitting applications is on 15 May 2020.




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Will General Budget Fuel the Real Growth Engine?

The intuitive habit of drawing macroeconomic conclusions (about India) from the corporate feedback (and vice versa) is fraught with risk. After all, only half of India’s GDP and 10% of India’s employment are in the formal sector. Further, only a fraction of the formal sector is listed.” This is not any Swadeshi ideologue speaking. This is what the Asia Pacific/India Equity Research paper of Credit Suisse titled “India’s better half: The Informal Economy” says about the most unique aspect of Indian economy. The paper points out that corporate sector accounts for only one-fourth of the national capital formed – the share of listed corporates in it is even less, just […]



  • Banking and Finance
  • Real Estate Companies
  • Real Estate India

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What is MRP and can it predict the result of the UK general election?

A statistical technique called multi-level regression and post-stratification (MRP) correctly predicted the last UK election when other polls failed. This is how it works




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General election 2019: Why you should think climate change not Brexit

Brexit may seem important right now, but whoever wins the election will be in charge halfway to 2030 – a crucial time in efforts to limit dangerous warming, says Jacob Aron




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General Anesthesia Not Linked to Raised Risk for Dementia

Title: General Anesthesia Not Linked to Raised Risk for Dementia
Category: Health News
Created: 5/1/2013 12:35:00 PM
Last Editorial Review: 5/2/2013 12:00:00 AM




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The 7 Deadliest Emergency General Surgeries

Title: The 7 Deadliest Emergency General Surgeries
Category: Health News
Created: 4/27/2016 12:00:00 AM
Last Editorial Review: 4/28/2016 12:00:00 AM




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How Dangerous Is General Anesthesia?

Title: How Dangerous Is General Anesthesia?
Category: Procedures and Tests
Created: 3/5/2020 12:00:00 AM
Last Editorial Review: 4/7/2020 12:00:00 AM




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Women’s experiences of diagnosis and management of polycystic ovary syndrome: a mixed-methods study in general practice

BackgroundPolycystic ovary syndrome (PCOS) is a common lifelong metabolic condition with serious associated comorbidities. Evidence points to a delay in diagnosis and inconsistency in the information provided to women with PCOS.AimTo capture women’s experiences of how PCOS is diagnosed and managed in UK general practice.Design and settingThis was a mixed-methods study with an online questionnaire survey and semi-structured telephone interviews with a subset of responders.MethodAn online survey to elicit women’s experiences of general practice PCOS care was promoted by charities and BBC Radio Leicester. The survey was accessible online between January 2018 and November 2018. A subset of responders undertook a semi-structured telephone interview to provide more in-depth data.ResultsA total of 323 women completed the survey (average age 35.4 years) and semi-structured interviews were conducted with 11 women. There were five key themes identified through the survey responses. Participants described a variable lag time from presentation to PCOS diagnosis, with a median of 6–12 months. Many had experienced mental health problems associated with their PCOS symptoms, but had not discussed these with the GP. Many were unable to recall any discussion about associated comorbidities with the GP. Some differences were identified between the experiences of women from white British backgrounds and those from other ethnic backgrounds.ConclusionFrom the experiences of the women in this study, it appears that PCOS in general practice is not viewed as a long-term condition with an increased risk of comorbidities including mental health problems. Further research should explore GPs’ awareness of comorbidities and the differences in PCOS care experienced by women from different ethnic backgrounds.




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A quick reference guide for rare disease: supporting rare disease management in general practice




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Fitter, Better, Sooner: helping your patients in general practice recover more quickly from surgery




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Patient and public involvement in general practice research




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Connecting General Practitioners Through a Peer-Facilitated Community of Practice for Chronic Disease Care [Innovations in Primary Care]




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Anticoagulants Safety and Effectiveness in General Practice: A Nationwide Prospective Cohort Study [Original Research]

PURPOSE

Most real-world studies on anticoagulants have been based on health insurance databases or performed in secondary care. The aim of this study was to compare safety and effectiveness between patients treated with vitamin K antagonists (VKAs) and patients treated with direct oral anticoagulants (DOACs) in a general practice setting.

METHODS

The CACAO study (Comparison of Accidents and their Circumstances with Oral Anticoagulants) is a multicenter prospective cohort study conducted among ambulatory patients taking an oral anticoagulant. Participants were patients from the study’s cross-sectional phase receiving oral anticoagulants because of nonvalvular atrial fibrillation, for secondary prevention of venous thromboembolism, or both. They were followed as usual for 1 year by their general practitioners, who collected data on changes in therapy, thromboembolic events, bleeding, and deaths. All events were adjudicated by an independent committee. We used a propensity score and a Cox regression model to derive hazard ratios.

RESULTS

Between April and December 2014, a total of 3,082 patients were included. At 1 year, 42 patients (1.7%) had experienced an arterial or venous event; 151 (6.1%) had experienced bleeding, including 47 (1.9%) who experienced major bleeding; and 105 (4.1%) had died. There was no significant difference between the VKA and DOAC groups regarding arterial or venous events, or major bleeding. The VKA group had a lower risk of overall bleeding (hazard ratio = 0.65; 95% CI, 0.43-0.98) but twice the risk of death (hazard ratio = 1.98; 95% CI, 1.15-3.42).

CONCLUSIONS

VKAs and DOACs had fairly similar safety and effectiveness in general practice. The substantially higher incidence of deaths with VKAs is consistent with known data from health insurance databases and calls for further research to understand its cause.




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General Practitioners in US Medical Practice Compared With Family Physicians [Original Research]

PURPOSE

General practitioners (GPs) are part of the US physician workforce, but little is known about who they are, what they do, and how they differ from family physicians (FPs). We describe self-identified GPs and compare them with board-certified FPs.

METHODS

Analysis of data on 102,604 Doctor of Medicine and Doctor of Osteopathy physicians in direct patient care in the United States in 2016, who identify themselves as GPs or FPs. The study used linking databases (American Medical Association Masterfile, American Board of Family Medicine [ABFM], Area Health Resource File, Medicare Public Use File) to examine personal, professional, and practice characteristics.

RESULTS

Of the physicians identified, 6,661 self-designated as GPs and 95,943 self-designated as FPs. Of the self-designated GPs, 116 had been ABFM certified and were excluded from the study. Of the remaining 102,488 physicians, those who self-designated as GPs but were never ABFM certified constituted the GP group (n = 6,545, 6%). Self-designated FPs that were ABFM certified made up the FP group (n = 79,449, 78%). The remaining self-designated FPs not ABFM certified constituted the uncertified group (n = 16,494, 16%). GPs differed from FPs in every characteristic examined. Compared with FPs, GPs are more likely to be older, male, Doctors of Osteopathy, graduates of non-US medical schools, and have no family medicine residency training. GPs practice location is similar to FPs, but GPs are less likely to participate in Medicare or to work in hospitals.

CONCLUSIONS

GPs in the United States are a varied group that differ from FPs. Researchers, educators, and policy makers should not lump GPs together with FPs in data collection, analysis, and reporting.




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Genetic and Circulating Biomarker Data Improve Risk Prediction for Pancreatic Cancer in the General Population

Background:

Pancreatic cancer is the third leading cause of cancer death in the United States, and 80% of patients present with advanced, incurable disease. Risk markers for pancreatic cancer have been characterized, but combined models are not used clinically to identify individuals at high risk for the disease.

Methods:

Within a nested case–control study of 500 pancreatic cancer cases diagnosed after blood collection and 1,091 matched controls enrolled in four U.S. prospective cohorts, we characterized absolute risk models that included clinical factors (e.g., body mass index, history of diabetes), germline genetic polymorphisms, and circulating biomarkers.

Results:

Model discrimination showed an area under ROC curve of 0.62 via cross-validation. Our final integrated model identified 3.7% of men and 2.6% of women who had at least 3 times greater than average risk in the ensuing 10 years. Individuals within the top risk percentile had a 4% risk of developing pancreatic cancer by age 80 years and 2% 10-year risk at age 70 years.

Conclusions:

Risk models that include established clinical, genetic, and circulating factors improved disease discrimination over models using clinical factors alone.

Impact:

Absolute risk models for pancreatic cancer may help identify individuals in the general population appropriate for disease interception.




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House Republicans demand Postmaster General turn over plan for financial stability

Republicans on the House Oversight Committee said Friday repeated efforts to learn how the cash-strapped U.S. Postal Service intends to become financially stable have been stymied by U.S. Postmaster General Megan Brennan.

The lawmakers say they've requested a financial plan from Ms. Brennan three different times, but it hasn't been ...




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US Surgeon General Jerome Adams defends drug and drinking coronavirus advice to black and Latino people

Follow our live coronavirus updates HERE Coronavirus: the symptoms




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Zoom To Crack Down on Zoombombing, In Deal With NY Attorney General

The company has agreed to launch a new internal data security program and will take other steps to combat hacker disruptions.




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Jennie Formby resigns as general secretary of Labour Party

Jennie Formby has resigned as Labour's general secretary as new leader Sir Keir Starmer reshapes the party.




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Top U.S. General On COVID-19, Reorienting For Great Power Competition

Steve Inskeep talks to Gen. Mark Milley, chairman of the Joint Chiefs of Staff, about the coronavirus threat within the ranks of the military, and guarding against a power competition with China.




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Trump's pick for coronavirus inspector general faces questions about independence

The Trump administration’s nominee for inspector general overseeing billions in Treasury Department coronavirus relief funds is facing skepticism from Democrats who fear that he will not show sufficient independence.





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Nurse moved serenely between generals and beggars in the street

Mother Teresa expected much of others but even more of herself.




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Nurse moved serenely between generals and beggars in the street

Mother Teresa expected much of others but even more of herself.




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Nurse moved serenely between generals and beggars in the street

Mother Teresa expected much of others but even more of herself.




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General Motors to restart production in St. Catharines next week

General Motors says it plans to restart some production at its engine plant in St. Catharines, Ont. next week ahead of a wider restart of North American operations the week of May 18.



  • News/Canada/Hamilton

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New York attorney general's office questioned NBC News employees on sexual harassment

Former anchor Linda Vester and others have been called in.




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Merck names Doina Ionescu as UK and Ireland general manager

Dr Mike England joins as medical director for UK & ROI




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General Pharmaceutical Council appoints Laura Fraser as director for Scotland

The General Pharmaceutical Council has appointed Laura Fraser, former clinical fellow for the Scottish Chief Pharmaceutical Officer as the new Director for Scotland.

Fraser has held leadership roles in community pharmacy across Scotland including board member of Community Pharmacy Scotland. She has also worked for the Scottish Government as Clinical Leadership Fellow. Prior to her position as board member she was area and regional manager for nearly nine years.

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Attorney General Eric Holder Addresses Department of Justice Employees

The Justice Department has aptly been described as the “crown jewel” of the federal government. It has attained this distinction not because of any laws or regulations, cases or controversies, buildings or equipment, but rather because of the quality, integrity, and dedication of the people who work tirelessly to carry out the Department’s vital mission.




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General Maritime Management (Portugal) Fined $1 Million for Enviromental Crimes

A federal judge in Corpus Christi, Texas, has sentenced General Maritime Management (Portugal), the operator of a fleet of tanker vessels, and two crewmembers of the motor tanker Genmar Defiance for making false statements to the U.S. Coast Guard and failing to maintain an accurate Oil Record Book designed to prevent pollution of the world’s oceans as required by United States and international law.



  • OPA Press Releases

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Statement of Attorney General Eric Holder Regarding United States V. Theodore F. Stevens

“In connection with the post-trial litigation in United States v. Theodore F. Stevens, the Department of Justice has conducted a review of the case, including an examination of the extent of the disclosures provided to the defendant. After careful review, I have concluded that certain information should have been provided to the defense for use at trial. In light of this conclusion, and in consideration of the totality of the circumstances of this particular case, I have determined that it is in the interest of justice to dismiss the indictment and not proceed with a new trial."



  • OPA Press Releases

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Deputy Attorney General David Ogden at the Attorney General’s Law Enforcement Summit

"Community policing in the United States is built on two partnerships: first, and fundamentally, the partnership between state, local and tribal law enforcement and the communities they serve. And second, the partnership between these law enforcement agencies and the Department of Justice."




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Attorney General Holder Announces Recovery Act Grants to Save or Create Justice Related Jobs

U.S. Attorney General Eric Holder today announced that more than $424 million in Recovery Act funds will go to 20 states, territories and the District of Columbia to maintain or increase public safety, while creating or retaining jobs within the law enforcement community.



  • OPA Press Releases

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Deputy Attorney General David Ogden's Address at the American Bar Association Section of Litigation 2009 Annual Conference John Minor Wisdom Public Service and Professionalism Awards Luncheon

"To ensure that the Department holds itself to the highest standards during discovery -- as in every stage of litigation -- in our criminal cases, and also in our civil litigation, we have taken both short-term and long-term action."




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Deputy Attorney General David W. Ogden at His Installation Ceremony

"This is an exciting time as well as a challenging one, and under the leadership of this President and this Attorney General, we are up for the job together."




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Attorney General Eric Holder at the Semi-Annual Conference of the Office of Overseas Prosecutorial Development Assistance and Training (OPDAT) Resident Legal Advisors and Foreign Service Nationals

"Helping foreign countries improve their criminal justice systems so they can cooperate more effectively with us and with their neighbors in real time is an important aspect of this department’s mission."




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Associate Attorney General Tom Perrelli Before the United States Senate Committee on the Judiciary in a Hearing Entitled “Helping State and Local Law Enforcement”

"If our partnership with state, local and tribal law enforcement is to endure, federal financial support cannot be a one time occurrence. This country is facing prolonged problems that require steadfast commitment and long-term cooperation."




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Attorney General Eric Holder at the National Law Enforcement Officers Memorial Fund Candlelight Vigil

"Tonight we hold a vigil, but every day we must be vigilant. So let us bind ourselves together with a new bond of service -- to make our country brighter, safer and more hopeful -- and in so doing, let us honor the memory of our fallen heroes every day."




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Attorney General Eric Holder at the National Peace Officers’ Memorial Service

"Let us bind ourselves together in a new bond of service -- to make our country brighter, safer, and more hopeful -- and in so doing, let us bear true witness to the legacies of our fallen heroes."




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Attorney General Eric Holder at the University of Pennsylvania Department of Criminology Commencement Ceremony

"You will be starting your service at a time when your government is placing a new and long overdue value on the scientific skills you have developed in this program."




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Attorney General Eric Holder Delivers Remarks at Columbia College Commencement

"Graduates, as you dive head first toward tomorrow, I call upon you to never loosen nor lose your grip on hope. The optimism that seems to come naturally with youth need not be lost as the years pass."




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Deputy Attorney General David W. Ogden at the National Missing Children’s Day Ceremony

"Preventing the sexual exploitation of children, and stopping and punishing those who do it are a leading priority. The Department aggressively enforces the laws at our disposal to protect our children."