ai Assam Governor attends Sainik school Goalpara's Diamond Jubilee celebrations By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:42:03 +0530 Full Article
ai DRDO conducts maiden flight test of Long-Range Land Attack Cruise Missile (LRLACM) By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:44:02 +0530 Full Article
ai HC modifies the status quo order on maintaining constructions for Tent City in two islands of Lakshadweep By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:14:08 +0530 Full Article Kochi
ai HC quashes magistrate court’s directive to register FIR against police officers By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:36:51 +0530 Magistrate court’s order to file FIR against police officers, including IPS officer and former Malappuram Superintendent of Police Sujith Das, in connection with an alleged sexual assault case quashed Full Article Kerala
ai China's largest air show takes off with fighter jets, attack drones By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:39:52 +0530 China has poured resources into modernising and expanding its aviation capabilities as it faces off against the United States and others around regional flashpoints like Taiwan. Full Article World
ai COP29: India, other developing countries demand fair climate finance commitments By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:33:21 +0530 India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments Full Article Environment
ai Lebanon media claims Israeli strike hit apartment south of Beirut By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:10:43 +0530 Israeli warplanes launched a strike at dawn targeting a residential apartment in a building in the Dawhet Full Article World
ai IndiGo, Air India cancel flights to Bali following volcanic eruption By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:23:06 +0530 The Mount Lewotobi Laki Laki volcano located in a remote island in East Nusa Tenggara province erupted earlier this month and has resulted in ash clouds Full Article India
ai Senior Russian naval officer killed in car bombing claimed by Kyiv By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:28:48 +0530 Russia's state Investigative Committee said in a statement that an improvised explosive device had detonated in an act of terrorism, killing a serviceman whom it did not identify Full Article World
ai Chemical synthetic approaches to mimic the TRAIL: promising cancer therapeutics By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3639-3651DOI: 10.1039/D4MD00183D, Review ArticleAbdullah-Al Masum, Shin Aoki, Md. Mahbubur Rahman, Yosuke HisamatsuTRAIL induced apoptosis signalling by death receptors (DR4/DR5).The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai New ATP-competitive inhibitors of E. coli GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3759-3777DOI: 10.1039/D4MD00498A, Research ArticleLucas Gutierrez, Peter Peršolja, Rodrigo Tosso, Nace Zidar, Danijel Kikelj, Ricardo D. EnrizA diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai Discovery of hybrid Glypromate conjugates with neuroprotective activity against paraquat-induced toxicity By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3711-3727DOI: 10.1039/D4MD00584H, Research ArticleSara C. Silva-Reis, Vera M. Costa, Daniela Correia da Silva, David M. Pereira, Xavier Cruz Correia, Xerardo García-Mera, José E. Rodríguez-Borges, Ivo E. Sampaio-DiasA series of bicyclic-based Glypromate conjugates with reduction of protein aggregation elicited by Aβ25–35 and neuroprotective activity against paraquat-induced toxicity is reported, paving the way for the discovery of novel neurotherapeutics.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai Stachydrine, a pyrrole alkaloid with promising therapeutic potential against metabolic syndrome and associated organ dysfunction By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3652-3673DOI: 10.1039/D4MD00425F, Review ArticleSemim Akhtar Ahmed, Prasenjit Manna, Jagat Chandra BorahMetabolic syndrome is a multifaceted condition marked by interconnected risk factors, significantly increasing the risk of serious diseases like cardiovascular disease, type 2 diabetes, and stroke.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3862-3879DOI: 10.1039/D4MD00313F, Research ArticleDaniele Pala, David Clark, Christine Edwards, Elisa Pasqua, Laura Tigli, Barbara Pioselli, Piotr Malysa, Fabrizio Facchinetti, Fabio Rancati, Alessandro AccettaThis study reports a novel, potent and selective series of ROCK inhibitors based on 8-(azaindolyl)-benzoazepinones identified through a core-hopping strategy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai Advances in Detecting Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Using Molecular Receptors and Nanostructured Assemblies By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00661E, Review ArticleAvijit Kumar DasThe detection and quantification of non-steroidal anti-inflammatory drugs (NSAIDs) are crucial due to their widespread use and potential impact on human health and the environment. This review provides a comprehensive...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ai Supreme Court stays order for CBI probe into sexual assault of minor in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:07:47 +0530 Calls for a list of five to seven direct recruit IPS officers, including three women, who hail from other States but are now serving in Tamil Nadu cadre Full Article Tamil Nadu
ai AIADMK will not form an alliance with BJP in 2026 polls, reiterates Palaniswami By www.thehindu.com Published On :: Wed, 13 Nov 2024 16:30:55 +0530 “During the Lok Sabha election, it was said at the party headquarters and in press bytes that the AIADMK will not have alliance with the BJP in the [2026] Assembly election,” he said Full Article Tamil Nadu
ai Southern Railway refuses to share inquiry report of Perumon train tragedy By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:15:33 +0530 105 people had died in after several coaches of the Island Express fell into the Ashtamudi Lake in 1988 Full Article Tamil Nadu
ai Delhi airport sees seven flight diversions owing to bad weather By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:39:37 +0530 The IMD reported that very dense fog began forming at around 5.30 a.m., resulting in a thick haze over various parts of Delhi Full Article Delhi
ai Delhi’s air quality turns ‘severe’ for first time this season: CPCB By www.thehindu.com Published On :: Wed, 13 Nov 2024 17:52:21 +0530 According to Central Pollution Control Board data, Delhi’s air quality reaches ‘severe’ levels with AQI of 418 Full Article Delhi
ai Arvinder Singh Sahney is new chairman of Indian Oil By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:43:29 +0530 Full Article Business
ai Free and fair inquiry sought into death of snakebite victim in Srikakulam district By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:10:47 +0530 Son of the victim alleges that local medical and health officials misleading higher-ups regarding the incident Full Article Andhra Pradesh
ai Fervour marks ‘Kaisika Dwadasi’ at Tirumala By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:22:52 +0530 Full Article Andhra Pradesh
ai Incessant rains cause landslides on Tirumala ghat road By www.thehindu.com Published On :: Wed, 13 Nov 2024 18:56:12 +0530 Full Article Andhra Pradesh
ai Target is to to make 30,000 MT of sand available every day in East Godavari district, says Collector By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:25:35 +0530 P. Prasanthi warns boatmen associations of stringent action if they attempt to prevent vehicles transporting sand from the sand reaches Full Article Andhra Pradesh
ai PAG report points out Andhra Pradesh govt.’s failure to disclose quantum of off-budget borrowings in Budget By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:19:16 +0530 Principal amount outstanding in 2019-20 was ₹67,171 crore, and it touched ₹1,54,797 crore in 2023-24, says the PAG report released by the I&PR Department Full Article Andhra Pradesh
ai RLDA invites bids for commercial land use in Tirupati railway station By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:29:31 +0530 The station is being developed on a massive scale, providing commuting area on the southern side, in view of the crammed locality on the northern side Full Article Andhra Pradesh
ai Jagan dares govt. to arrest him, says will continue to ‘expose failures’ By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:16:05 +0530 Full Article Andhra Pradesh
ai Police book Sri Reddy for posting ‘defamatory content’ against Chandrababu Naidu, Pawan Kalyan By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:25:39 +0530 Full Article Andhra Pradesh
ai Andhra Pradesh High Court strikes down PIL seeking to restrain police from taking action on ‘abusive content on social media’ By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:30:39 +0530 Full Article Andhra Pradesh
ai Supreme Court sets pan-India guidelines against ‘bulldozer justice,’ calls demolitions without due process unconstitutional By www.thehindubusinessline.com Published On :: Wed, 13 Nov 2024 11:31:53 +0530 The Apex court maintains that these guidelines do not apply in cases of unauthorized public land construction or where demolition is mandated by a court ruling Full Article News
ai Peddapalli goods train derailment: Several trains cancelled or diverted By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:43:36 +0530 Three railway lines were affected in the derailment. Some trains skipped stoppages. Full Article Telangana
ai Hyderabad Airport wins global recognition for digital innovations By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:14:32 +0530 Full Article Hyderabad
ai Metro Rail services to be extended to Medchal and other parts of northern Hyderabad under Phase-III: Telangana CM By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:18:36 +0530 Full Article Hyderabad
ai Doctor stabbed at Kalaignar Centenary Super Speciality Hospital in Chennai; one arrested By www.thehindu.com Published On :: Wed, 13 Nov 2024 12:24:15 +0530 The oncologist who was attacked has been identified as Balaji Jagannath. He has been admitted in the ICU, and his condition is said to be critical Full Article Chennai
ai COP29: India, other developing countries demand fair climate finance commitments By www.thehindu.com Published On :: Wed, 13 Nov 2024 13:33:21 +0530 India, LMDCs advocate for equitable climate finance at COP29, pushing for transparency, fairness, and flexibility in financial commitments Full Article World
ai Karnataka Chief Minister Siddaramaiah says no proposal to ease night traffic ban through Bandipur By www.thehindu.com Published On :: Wed, 13 Nov 2024 14:45:12 +0530 Deputy Chief Minister D.K. Shivakumar had stated, in Wayanad in Kerala, that the government would take all possible measures to lift night traffic ban through Bandipur, which had riled wildlife conservationists in Karnataka Full Article Karnataka
ai ED’s investigation into MUDA case is based on false allegations, says Siddaramaiah By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:12:55 +0530 Full Article Karnataka
ai Illegal export of iron ore from Belekeri port: Karnataka High Court suspends sentence and grants bail to MLA Satish Sail and five other convicts By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:21:10 +0530 Full Article Karnataka
ai FIR registered against Snehamayi Krishna By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:21:22 +0530 Full Article Karnataka
ai Only education can empower women: Siddaramaiah By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:33:50 +0530 Full Article Karnataka
ai Marakumbi atrocity case: 99 persons granted bail by High Court Dharwad Bench By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:34:18 +0530 Full Article Karnataka
ai Mysuru to host conference on AI and Deeptech By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:45:37 +0530 Full Article Karnataka
ai MUDA ‘scam’: Raichur MP Kumar Naik, CM’s PA questioned by ED By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:52:50 +0530 Full Article Karnataka
ai After hosting World Cup, Qatar praised by U.N. rights body for labour law reforms but urged to do more By www.thehindu.com Published On :: Wed, 13 Nov 2024 11:06:56 +0530 In Qatar, better labour law protections have been passed in recent years relating to a minimum wage, freedom to change employers and combating forced labor and trafficking Full Article World
ai Why US chess champ Levon Aronian is connecting with the Armenian community in Chennai By www.thehindu.com Published On :: Wed, 13 Nov 2024 15:54:02 +0530 Chess champion Levon Aronian, who competed in Chennai Grand Masters recently, on future Indian chess superstars Full Article Sport
ai Comeback man Shami hogs the spotlight as MP takes honours on opening day against Bengal By www.thehindu.com Published On :: Wed, 13 Nov 2024 19:38:38 +0530 Full Article Sport
ai Ranji Trophy | Tamil Nadu has Railways under the cosh with dominant show By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:18:55 +0530 CRICKET | Skipper Jagadeesan’s decision to field pays off handsomely as Ajith Ram and Gurjapneet take quick wickets; Ahuja, Saif and Merai hold out with half centuries Full Article Cricket
ai Siddhant Banthia sails past Siddharth Vishwakarma in ITF men’s tennis tournament By www.thehindu.com Published On :: Wed, 13 Nov 2024 20:37:44 +0530 Siddhant Banthia broke serve dropping one point, and served out at love in the next game, to gain a stranglehold over the proceedings. He ran up a 5-1 lead in the second set before closing it out without any trouble Full Article Sport