Inflammation represents a long-conserved biological process characterized by the release of chemical messengers that regulate the immune response.  Wh

Inflammation represents a long-conserved biological process characterized by the release of chemical messengers that regulate the immune response.  Wh

Likely due to high temperatures and uncoordinated treatmentToronto, ON – High ocean temperatures and poor timing of parasite management likely led to an epidemic of sea lice in 2015 throughout salmon farms in British Columbia’s Queen Charlotte Strait, a University of Toronto-led study has found. The sea lice spread to migrating juvenile wild salmon, resulting in […]

The thermal properties of polymeric materials are important to the function of components and assemblies that will operate in cold or warm environments.

The TR-71nw supports automated, error-free data collection, remote monitoring and alerting with a simple Ethernet LAN connection.

The unique valve design of V-traps makes them virtually trouble free. They are self-priming; you never have to add water to make them work. A self-sealing column of water, equal in height to the negative pressure in the air conditioner, automatically prevents air from entering the drain trap allowing the condensate to drain freely.

Repairing reach-in coolers and freezers with electronic temperature controllers can be challenging at times.

What happens in the condenser is a direct reflection of what is happening in the rest of the refrigeration system.

By splitting the absorption process into two steps, lithium bromide solution concentrations are lower in the system, enabling lower hot water temperatures within the generator, lower hot water flow rates, and the elimination of crystallization risk within the chiller.

This product now features mercury-free temperature elements as an option in any 8- or 12-inch case configuration, in ranges between minus 30˚ and 600˚F.

Science Shock: U.K. Met Office is “Inventing” Temperature Data from 100 Non-Existent Stations by Chris Morrison Shocking evidence has emerged that points to the U.K. Met Office inventing temperature data from over 100 non-existent weather stations. The explosive allegations have been made by citizen journalist Ray Sanders and sent to the new Labour Science Minister Peter Kyle MP. […]

YSTR-DG.CoAP - oneM2M-Developer Guide of CoAP binding and long polling for temperature monitoring

Metl-Span panels for the roof and walls not only created a beautiful community center, but regulates the temperature for various activities held there.

FourKites has announced that Teva, a global provider of generic medicines, has achieved a 0.005% incident rate by leveraging FourKites’ global carrier visibility solution, NIC-Place.

By Mary Heiser, Director, Industry & Product Marketing, FourKites.

In today’s intricate food and beverage supply chains, ensuring product quality from farm to fork is paramount. One of the most crucial factors determining the integrity of perishable products is temperature. As any supply chain professional knows, even a slight temperature deviation can mean the difference between delivering a delicious ice cream cone or a disappointing puddle.

Aramex UK has urged pharmaceutical companies exporting products overseas to be mindful about shipping to warmer climates.

It was the hottest August in records dating back to the 1800s — and the heat goes on.

Ignat V. Shilov
Sep 1, 2007; 6:1638-1655
Technology

Alzheimer's disease (AD) is characterized by neuronal loss and accumulation of β-amyloid-protein (Aβ) in the brain parenchyma. Sleep impairment is associated with AD and affects about 25–40% of patients in the mild-to-moderate stages of the disease. Sleep deprivation leads to increased Aβ production; however, its mechanism remains largely unknown. We hypothesized that the increase in core body temperature induced by sleep deprivation may promote Aβ production. Here, we report temperature-dependent regulation of Aβ production. We found that an increase in temperature, from 37 °C to 39 °C, significantly increased Aβ production in amyloid precursor protein-overexpressing cells. We also found that high temperature (39 °C) significantly increased the expression levels of heat shock protein 90 (Hsp90) and the C-terminal fragment of presenilin 1 (PS1-CTF) and promoted γ-secretase complex formation. Interestingly, Hsp90 was associated with the components of the premature γ-secretase complex, anterior pharynx-defective-1 (APH-1), and nicastrin (NCT) but was not associated with PS1-CTF or presenilin enhancer-2. Hsp90 knockdown abolished the increased level of Aβ production and the increased formation of the γ-secretase complex at high temperature in culture. Furthermore, with in vivo experiments, we observed increases in the levels of Hsp90, PS1-CTF, NCT, and the γ-secretase complex in the cortex of mice housed at higher room temperature (30 °C) compared with those housed at standard room temperature (23 °C). Our results suggest that high temperature regulates Aβ production by modulating γ-secretase complex formation through the binding of Hsp90 to NCT/APH-1.

Ricardo Bermudez-Otero and Tobias Galla discuss the mathematics describing the evolution of human languages. The sounds and structures of the world's approximately 7,000 languages never stop changing. Just compare the English in Romeo and Juliet or the Spanish in Don Quixote to the modern forms. But historical records give an incomplete view of language evolution. Increasingly, linguists draw upon mathematical models to figure out which features of a language change often and which ones change more rarely over the course of thousands of years. A new model inspired by physics assigns a "temperature" to many sounds and grammatical structures. Features with higher temperatures are less stable, so they change more often as time goes on. The linguistic thermometer will help researchers reconstruct how our languages came to be, and how they might change in future generations.

The world’s slowest mammal is at risk of extinction by the end of the century due to their low metabolic rate and climate change

CBC Sports' daily newsletter breaks down whose fortunes are looking up and whose are down after the weekend's winter Olympic sports action.

Pioneering Technology Allows Surgeons to Cut Precisely and Control Bleeding Without Causing Heat Damage to Tissue

Delhi's air quality remained "very poor" for a 14th consecutive day on Tuesday, with an AQI reading of 334, as vehicular emission was the biggest contributor to the city's pollution, accounting for 15.4 per cent.

Delhi's air quality remained "very poor" for a 14th consecutive day on Tuesday, with an AQI reading of 334, as vehicular emission was the biggest contributor to the city's pollution, accounting for 15.4 per cent.

The reefs in Eilat displayed widespread bleaching, a phenomenon in which the symbiosis between coral and algae fails, typically due to high water temperatures.

The Head of Impact Assessment and Adaptation, Henry Neufeldt, UN Environment Programme Copenhagen Climate Centre, has called for increased climate adaptation funding, particularly for developing nations facing significant climate risks. UNEP’s latest report reveals an acute adaptation finance gap, with current international funding for developing countries at USD 30 billion—far below the USD 200 to 400 […]

A practical superconductor would transform the efficiency of electronics. After decades of hunting, several key breakthroughs are inching us very close to this coveted prize

A solar energy absorber that uses quartz to trap heat reached 1050°C in tests and could offer a way to decarbonise the production of steel and cement

Physicists have coaxed a cloud of atoms into having a temperature beyond absolute zero and placed them in a geometric structure that could produce an unknown form of matter

Title: As Temperatures Fall, Heart Attacks May Rise
Category: Health News
Created: 8/29/2017 12:00:00 AM
Last Editorial Review: 8/30/2017 12:00:00 AM

Thermoregulation, responsible for maintaining a stable core temperature during wide fluctuations in external and internal thermal environments, is an iconic homeostatic process. However, we suggest that despite its fundamental physiological significance, the potential for required cool housing temperatures and thermoregulatory mechanisms to influence the interpretation of experimental data is not sufficiently appreciated. Moreover, although it is generally assumed that the major thermoregulatory pathways are well understood, here we discuss new research that suggests otherwise and reveals the emergence of a new wave of exciting ideas for this "old" field of research.

Researchers show the average surface temperature on our planet has shifted between 51.8 to 96.8 degrees Fahrenheit

As winter arrives and daylight hours decrease, it gets easier to hit the snooze button and stay in bed. It turns out that there’s a scientific reason behind this phenomenon that helps to explain why people struggle to adjust their internal clocks—also known as circadian rhythm or sleep-wake cycle—when the weather turns colder.

medlinkDengue/medlink, a recurring tropical disease that experiences outbreaks during the monsoon season, becomes more aggressive and severe in animal

The escalating impact of climate change is anticipated to expand the reach of medlinkdengue/medlink, a mosquito-borne disease claiming thousands of

Chinese scientists found that anomalies in tropical Indian Ocean sea surface temperatures can forecast the severity of global medlinkdengue outbreaks/medlink (!--ref1--).

The temperature of one's medlinkchildhood/medlink home and the sense of community connectedness can help predict how U.S. residents set their thermostats,

IWMI and CIMMYT warn of changing climate patterns in South Africa.

The post Farmers urged to prepare for El Niño to trigger record-high temperatures first appeared on International Water Management Institute (IWMI).

Bird flu or avian influenza virus does not infect people as the virus is heat liable, degraded and killed when subjected to high temperature, said health experts.

Shraddha Das has shared her hot bikini avatars from her recent vacation in Bali in Indonesia.

Pictures of Bigg Boss Tamil 3 contestant Sakshi Agarwal's photoshoot are here.

Have you ever noticed how your mood can change with the weather? A gloomy, rainy day might leave you feeling down, while a warm, sunny afternoon can lift your spirits. But what if there's more to this connection than just a

Following intermittent rains, Delhi-NCR has been witnessing heat and humidity for the past few days.