At first, all Sophia Young wanted was to find a job until she could find a husband. Instead, she finds herself working for Scott Kraft, a notoriously unpredictable and demanding tech mogul. She soon becomes more interested in her work in investor relations than in getting married, which she never planned on. She is quickly promoted and becomes an asset at Kraft’s new business, an animation company called Treehouse that’s set to disrupt the movie industry. Fans of Pixar, Apple and Steve Jobs will enjoy the parallels between Jobs and the fictional Kraft. Kraft, who founded a revolutionary technology company called Quince before taking over Treehouse, also creates the first wave of smart phones, known as “Q-phones.” Similarly, author Anna Yen pays homage to Pixar, where she herself worked in investor relations. In the book, Treehouse creates movies like “The Amazings,” and “Treasures,” which seem to be a nod to Pixar’s real-life movies “The Incredibles” and “Toy Story.” As Sophia becomes

A special episode from Inflection Point with Lauren Schiller.

Tech companies in Silicon Valley are under the microscope for not living up to their idealistic pledges to save the world. On this week’s episode of Reveal, we investigate companies on the cutting edge that are struggling to solve some old-fashioned problems: Worker safety at Tesla, and diversity at Google and beyond.

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To understand new technology we need to comprehend the social, cultural and economic influences of the developers. Also, making direct comparisons between the human mind and Artificial Intelligence is counterproductive.

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• As the coronavirus-led economic shutdown drags on, many investors have started counseling startups to have more than a years' worth of "runway" to avoid having to raise funding on poor terms.
• But VCs are split on how much startups should be socking away. Some have estimated 18 months oof reserves could suffice, while others say as much as 3 years' worth of runway is ideal.
• The different time frames depends on the age of the startup along with which industry they operate in. Younger startups typically have fewer overhead expenses, while older startups likely have more employees and pricey office leases.
• Also, those companies that may be able to resume work as essential services may need less cash if they are able to generate revenue.
• VCs are uniformly bracing for an economic slowdown, but the severity of downturn is still up for debate. 
• Click here for more BI Prime stories.

Startups are facing what could become the worst economic downturn in several decades, and VCs are begging them to take drastic measures to improve their chances of making it through. 

Most Americans who lived through the 2008 financial crisis will know that a savings stockpile or rainy day fund can mean the difference between surviving and thriving during tough times, but as recent studies have shown, many tech startups and VC firms don't have a similar first-hand experience; many have only known boom times and are now venturing into uncharted waters.

One thing VCs agree on is that startups need to quickly rein in growth plans — ideally as soon as yesterday — and start scrutinizing expenses. Anything nonessential should be cut or suspended indefinitely, headcount should be reduced, and pricey office leases eliminated if possible, all with the goal of extending a startup's "runway."

In Silicon Valley, runway refers to how much cash a startup has on hand to put against its operating expenses. If, for example, a startup has roughly $100,000 in monthly operating expenses and has $1 million in the bank, they are looking at a 10-month runway, assuming revenue stays roughly flat.

In the days before the coronavirus pandemic, a startup's runway dictated when it had to start looking for additional funding. Instead of cutting expenses, the popular solution was to simply put more VC money in the bank. This helped high flying startups like Uber and Airbnb expand at a breakneck pace — VC dollars kept pouring in and the companies remained unprofitable as they chased growth at all costs.

But now, VCs are saying that's no longer an option. Founders Fund general partner Keith Rabois said on a podcast recently that profitability is now being rewarded much more than high-growth. 

For startups that aren't profitable, that means hunkering down and ensuring there are enough reserves to last through the crisis.

So how long does the runway need to be? 

Many VCs that Business Insider has spoken to are advising their startups to have at least 18 months of runway. But some VCs say startups should have upwards of 3 years' of expenses saved up. 

The length of time can vary depending on the startup, one investor told Business Insider, pointing to the startup's age and industry as important factors. An early-stage company with a handful of employees and low-overhead costs might easily stretch a $500,000 seed check, whereas a growth-stage biotech startup with hundreds of employees, expensive hardware, and pricey office space might struggle to make tens of millions of dollars in funding make it through 12 months. Those that can't cut costs will be forced to fundraise with poor terms and risk the dreaded downround. 

"You can always easily dial back up the aggressiveness and risk profile if we get more optimistic visibility, but if you don't take action right away — to preserve capital, cut your burn rate, have fundamentally attractive unit economics, edit the product to make more sense in the new world order — if you don't do those right away, the opportunity to do those things and survive is probably lost forever," Rabois said in the April Talkshow broadcast.

Rabois is in the camp of pessimists, generally speaking, who think the economic downturn will not only drag on through 2020, but could eventually turn into an economic depression the likes of which could rival the Great Depression of the 1930s. He said that his VC peers are starting to rein in the freewheeling deal-making that has defined the last two decades of the Silicon Valley startup ecosystem, and are now treading cautiously. It's time that startups do the same, he said.

SEE ALSO: Lower valuations and a long wait for funding: Two top early-stage VCs dish on how they are counseling startups to withstand long-term economic uncertainty

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David Price is in the host's chair this week, as the team talk about the latest hot tech topics. Tamlin Magee has got the drinks in - futuristic meal-replacement drinks called Soylent, which he forces everyone to try and which are apparently not people.

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What if the government ran more like Silicon Valley? Engineer Matt Cutts shares why he decided to leave Google (where he worked for nearly 17 years) for a career in the US government -- and makes the case that if you really want to make an impact, go where your help is needed most.

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Read Full Article at RT.com

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Based on evidence provided by customer receipts, the investigation confirmed that the pricing of several food items exceeded the 10-per cent increase allowed during a state of emergency, with some prices being as much as 200 per cent more.

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Allison Arieff asks that and a lot of other questions.

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CNBC.com's MacKenzie Sigalos brings you the day's top business news headlines, and what to watch as the coronavirus pandemic continues to keep most of America on lockdown. Today, CNBC's Kate Rooney also takes a look at the widespread layoffs hitting the lucrative tech sector and start-up scene.

Over a phone call from Kolkata, Vikram Rajan*, an audio engineer and guitarist formerly based out of Mumbai, wants us to listen to a track that he has composed. It's available on Soundcloud and, as we stream it, we more or less agree that its flavour of electronica-jazz could accompany a languorous Sunday evening. "For a long time, I had been unable to come up with something good. And, then, I composed this around March while I was microdosing and sometimes, megadosing on acid," says Rajan.

The 33-year-old is referring to a way-of-life that's effectively snapping the ties between drug abuse and the creative arts. This is a lifestyle experiment that some of the brightest techies in Silicon Valley are engaging in, and has got psychiatrists and anti-drug crusaders distraught. "From a 100 mics paper, I take about 20 mics, twice a week, giving the doses a 2-3 days gap. The effects of acid last for about six hours for me," says Rajan, who started experimenting with drugs as a teenager.

After a litany of prescriptions failed to control her mood swings and depression, Ayelet Waldman found relief in LSD. The former federal public defender authored A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life, in 2016. She wrote: "(It) made room in my mind not necessarily for joy, but for insight. It allowed me a little space to consider how to act in accordance with my values, not just react to external stimuli. This, not the razzle-dazzle of pleasure, was its gift." Pic/Getty Images

In need of a quick glossary before we proceed? Acid is officially called Lysergic Acid Diethylamide (LSD), a psychedelic drug banned in India, the possession of which can lead to imprisonment from one to 20 years under the Narcotic Drugs and Psychotropic Substances Act. LSD is often illegally sold in the form of stamps, with the hallucinogen embedded on blotter paper. Mics is micrograms, that's one-millionth of a gram. A microdose is when you have about one-tenth of a recreational 'party' dose, which starts at about 200 mics.

"With microdosing, you are not tripping — this is not a trip. The euphoria isn't there. It's not about feeling good, it's about calmness," continues Rajan. Microdosing first hit headlines after Steve Jobs' passed away in 2011, when a number of inspiring tales on how LSD became the new go-to substance for enhanced performance by tech employees hit the net. Espresso became passé. 'Flow states' were the new yoga. While Jobs did more than just microdose (he was known to have gone all the way), Silicon Valley techies are reportedly doing acid in quantities such that their effects are 'sub-perceptual', where you won't "see stuff" but you harness its "positive" effects.

A dropper with CBD cannabis oil, used for medicinal purposes. Initial research in the area has shown that patients can reap the benefits without its full-blown 'high' effects

Paul Austin, founder of The Third Wave, where you will find a manifesto on microdosing, defines it as, "the act of integrating sub-perceptual doses of psychedelics, such as LSD or Psilocybin Mushrooms, into your weekly routine for higher levels of creativity, more energy, increased focus, and improved relational skills." The Third Wave, according to Austin, follows the first two waves, in which psychedelics were used indigenously for thousands of years, and then, in the 60s and 70s, when they were a part of American counterculture. Austin writes that The Third Wave is upon us, "brought about by recent developments in cannabis legalisation and psychedelic research — and it will change the way mainstream culture perceives psychedelic use."

Classically acid, now weed
For Rajan, however, it wasn't sub-perceptual Silicon Valley that got him to ration his 100 mics stamps, each of which costs about R2,000. It was simply a matter of demand and supply. Mumbai had better stuff than Kolkata, and more availability. Microdosing has classically been associated with LSD, but now has been extended to cannabis as well. Austin's website has guided instructions for microdosing on nine drugs, including cannabis and ayahuasca. Mumbai-based communications officer Varna Kumar*, 25, smokes a mandatory post-work joint every night in order to cope with anxiety and panic attacks. "I feel I have worked enough through the day, without much time to understand what I am going through. At night, when I am by myself, I smoke a small joint to achieve REM sleep," she says. The joint, a mix of two strains, sativa and indica, help her body relax. It makes her anxiety seem defeatable, is how she describes it. Her counsellor, who also smokes up, has not advocated this as a coping mechanism. "It's different from when I am smoking up recreationally during the weekend or when I am away on a vacation. I will do three to four joints when I have nothing to take care of," she says.

Rajan doesn't buy it. He offers an example that may be best contemplated upon or contested by those who have done both LSD and cannabis. "With weed, you are either stoned, or you are not. You will need to smoke up as soon as the high wears off. When you get stoned, your mind becomes passive. But, microdosing on LSD allows you to be calm enough to multitask, allowing a lot of information to be funnelled into your brain easily. You are alert, you are awake," he says, adding, "What is LSD all about? When you start tripping, you see a shift in perspective." You need not agree with Rajan, as he himself says, "We are all chemical reactions", with each of us reacting differently to drugs.

Covert, not convenient
Microdosing will often be compared to that hard-earned and well-deserved one drink after work hours. It's nothing like that, microdosers will tell you, and so will psychiatrists and rehab therapists. For one, microdosing has none of the ease of getting a drink at your favourite pub. You will be persecuted in your search for your creative spell or a calmer mind. Next, it's not even like getting a drug prescription that your GP advises you to have for the course of a fortnight. Kumar and Rajan know it all too well. Microdosing means self-experimentation, knowing when you are crossing the threshold into recreational high dosages. Cannabis, for instance, is best microdosed through edibles, like space brownies, which are available legally in some parts of the world. It's probably the reason why microdosing is yet to take on Silicon Valley proportions in India. "Here, we don't often get to know what strain of cannabis we are using, or where it is sourced from," says Kumar. Saying "this stuff is craazzyy" is, therefore, not enough if you want to microdose. "If you are living with family, it's hard to make edibles. All this means that the convenience factor associated with a drink is not the same with this covert process," she adds.

The idea of the junkie, with matted hair and piercings, is a stereotype that microdosing is replacing. It's no longer cool to be a junkie, especially in the vegan-conscious, gluten-free, aerial yoga health lifestyle that we are seeing around us. Microdosing may be the most metrosexual among the various kinds of drug use, and it carries the allure of high-performance and alleviation of mental health issues, with published studies to back these up. But doctors and psychiatrists are warning us about the glamourisation of microdosing, even as research to mainstream it for mental health is going on. Psychiatrist Dr Samir Parikh says, "Microdosing encourages the thought process that you need a drug for enhanced performance or better creativity or to calm your nerves. This will mean that students microdose before exams, athletes before a run, couples before a wedding, and the next thing you know, because someone has to attend a birthday bash. There is no end to important situations in life. We are making people believe that a student could have scored an additional five marks in an exam had she just microdosed. Can you imagine the perils of this philosophy?" he says. He backs this up with the number of risks associated with prolonged drug abuse, such as a permanent change in brain circuitry, cerebrovascular diseases, and panic attacks.

Then there are those who will argue that moderation as 'one-drink-a-day' is more addictive than the weekend drunken revelry. Is addiction, even in microdoses, still addiction, where the brain searches for rewards compulsively? Kumar disagrees. "Microdosing is the difference between dependence and addiction. For example, I am dependent on a cab to take me to the station. Can I get through my day without it? Can I walk to the station? Yes, I can. That's what microdosing is. I can get through my day without a joint, but a joint just makes it a little easier," she says.Psychiatrist Dr Yusuf Merchant, who runs a rehabilitation centre at Kalyan, says microdoses pose the risk of turning into overdoses. "With any drug, the body learns to metabolise it faster. Which means, that the quantity for a microdose will keep increasing and your hold on reality will keep getting more tangential."

Rajan himself admits to a 'bad trip'. LSD users will tell you that recreational doses are best done in settings that you feel comfortable in, to enjoy, or cope, with the hallucinations. With microdosing, you are headed into your office or your studio to function better. Rajan had once taken more than a microdose, leading him to have a panic attack, the kind where he couldn't even see his hands. The golden rule, he says, is that if you don't go on a full trip, you will never know what a microdose is.

That ailing pain
The push for microdosing is coming from a quarter where its future seems to be most secured — pain management. Mumbai-based homemaker Susheela Kamath*, 48, was diagnosed with stage II breast cancer a couple of years ago, and having undergone nearly a year's worth of chemotherapy and radiation, the accompanying pain and nausea, were all too real. Her daughter provided her with high-grade hash oil. The dealer provided her with a tiny spoon, the kind that you are handed inflight to stir your coffee with. "I had to initially understand, through a lot of trial and error, by gauging my mother's mood, on what a microdose for her would be. Hash oil is very potent," says the daughter.

A little drop of it on her toast every day, helped Kamath cope with pain. "From the third day to the tenth day after chemotherapy, my mother would have about three to four spoons a day, and, on other days, just half a spoon," says the daughter. Coping with the pain meant she could do more during her day, and also have an appetite. Now, months after she has wound up chemotherapy and radiation, she has bid adieu to the prescription drugs that came along with it, and the hash oil as well, without yearning for that high. Unfortunately, unlike medical grade marijuana that is available in some countries, and still not permitted in India, the daughter did not know if the oil had cannabidiol (CBD), which gives marijuana its medical properties, or tetrahydrocannabinol (THC) which gives you the "high".

Dr Kailash Kothari, interventional spine and pain management specialist at Fortis Hospital, Mulund, says that there is not enough evidence to either prove or disprove that microdosing on cannabis can help with pain management, the way opioids, such as morphine, act on the nervous system. "Do cannabinoids work like tranquilisers or do they have long-term effect? There is not enough research as of now," he says, adding, "Getting dependent on these takes a lot of time and not something that can happen in about 15 days of use." In the meanwhile, you can enjoy a night of quiet or a better track on Soundcloud by rationing your stash. But, is it short-term solace or long-term abuse?

*All names have been changed on request to protect identity

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