sign SEMIFIVE and Synopsys Collaborate on HPC Chiplet Platform for Advanced Multi-Die Designs By www.hpcwire.com Published On :: Thu, 14 Nov 2024 02:26:10 +0000 SEOUL, South Korea, Nov. 13, 2024 — SEMIFIVE, a leading design solution provider and pioneer of platform-based custom silicon solutions, has announced its collaboration with Synopsys to develop a cutting-edge […] The post SEMIFIVE and Synopsys Collaborate on HPC Chiplet Platform for Advanced Multi-Die Designs appeared first on HPCwire. Full Article
sign Special counsel Jack Smith to wrap up Trump criminal cases, resign before Inauguration Day By www.upi.com Published On :: Wed, 13 Nov 2024 09:21:39 -0500 Special Counsel Jack Smith will wrap up the two criminal cases against Donald Trump and will resign with his team before Trump's Inauguration Day in January. Full Article
sign Denmark becomes 48th nation to sign Artemis Accords for space exploration By www.upi.com Published On :: Wed, 13 Nov 2024 18:59:15 -0500 Denmark is a founding member of the European Space Agency and on Wednesday formally committed to safe and responsible space exploration that benefits humanity by signing the Artemis Accords. Full Article
sign Carolina Hurricanes Assign Riley Stillman To Chicago Wolves By sports.yahoo.com Published On :: Wed, 13 Nov 2024 21:04:40 GMT 26-year-old recorded six points in 47 game with the Rochester Americans last season Full Article article Sports
sign Apple & A24 sign Lena Dunham to write movie about FTX crypto implosion By appleinsider.com Published On :: Wed, 13 Nov 2024 15:01:05 +0000 Apple and A24 are working on a film adaptation about Sam Bankman-Fried and the FTX crypto scandal, with the script set to be written by Lena Dunham.A representation of Bitcoin - Image Credit: Pixabay/Michael WuenschThe two studios are in the early stages of developing the film based on the New York Times bestseller "Going Infinite: The Rise and Fall of a New Tycoon" by Michael Lewis. The book covers the rise of Bankman-Fried, followed by the eventual discovery of missing funds at the cryptocurrency exchange and subsequent fraud charges.Lena Dunham has been attached to the film, reports Variety, having previously starred and produced the HBO series "Girls," as well as "Camping" and "Generation." Her work on "Girls" led to eight Emmy Award nominations, as well as one Golden Globe. Continue Reading on AppleInsider | Discuss on our Forums Full Article
sign M4 Mac mini review: The first redesign in years hides incredible computing power By appleinsider.com Published On :: Wed, 13 Nov 2024 20:31:15 +0000 Apple's long-overdue overhaul of the Mac mini shrinks an already great package even more, yet it still punches far above its weight class.M4 Mac miniI've owned a Mac mini since the very first G4 model. In an era of bulky towers and a G4 Cube just years before that impressed but didn't deliver, the little box brought Apple power to a small desktop package, and I was enthused.And since then, I've had one in service 24/7 constantly. Even now with a Mac Studio on my desk, there's one upstairs in use with a family member, one in the other room silently humming away acting as my network attached storage and test platform, and a few more on my shelf that I've hoarded over the years, just waiting for an application. Continue Reading on AppleInsider | Discuss on our Forums Full Article
sign iQOO Neo 10 Series Alleged Schematics Show Design, Tipped to Get 6.78-Inch Display By www.gadgets360.com Published On :: Wed, 13 Nov 2024 14:19:57 +0530 iQOO Neo 10 series is confirmed to debut in China soon as a follow-up to last year's Neo 9 family. We have heard multiple rumours regarding the processor and fast charging capabilities of the iQOO Neo 10 and iQOO Neo 10 Pro. A newly leaked schematics offer us a good look at their design. The leak also reveals the display details of the iQOO Neo 10 lineup. Full Article
sign 2026 Honda Passport revealed with bigger, brawnier design By www.motorauthority.com Published On :: Wed, 13 Nov 2024 09:00:00 -0500 Redesigned 2026 Honda Passport revealed ahead of launch in early 2025 2026 Honda Passport comes standard with 285-hp V-6 2026 Honda Passport pricing will start in mid-$40,000 range A new generation of the Honda Passport two-row midsize SUV is headed to showrooms early next year as a 2026 model. Buyers will be able to choose from a base RTL model... Full Article Los Angeles Auto Show
sign Poland hails opening of US missile base as sign of its security By www.voanews.com Published On :: Wed, 13 Nov 2024 10:01:46 -0500 The United States opened a new air defense base in northern Poland on Wednesday, an event the European nation's president said showed the country was secure as a member of NATO even as Russia wages war in neighboring Ukraine. Situated in the town of Redzikowo near the Baltic coast, the base has been in the works since the 2000s. At a time when Donald Trump's election victory has caused jitters among some NATO members, Warsaw says the continued work on the base by successive U.S. presidents shows Poland's military alliance with Washington remains solid whoever is in the White House. "The United States... is the guarantor of Poland's security," President Andrzej Duda said. He said the permanent presence of U.S. troops at the base showed that Poland, a communist state until 1989, was "not in the Russian sphere of influence." The Kremlin on Wednesday called the base a bid to contain Russia by moving American military infrastructure nearer its borders. The opening comes amid a nervous reaction among some NATO members to the election of Trump, who has vowed not to defend countries that do not spend enough on defense. However, Poland says it should have nothing to fear as it is the alliance's biggest spender on defense relative to the size of its economy, and conservative Duda has stressed his warm ties with Trump. The U.S. base at Redzikowo is part of a broader NATO missile shield, dubbed "Aegis Ashore," which the alliance says can intercept short- to intermediate-range ballistic missiles. Other key shield elements include a site in Romania, U.S. navy destroyers based in the Spanish port of Rota and an early-warning radar in Kurecik, Turkey. Moscow had already labeled the base a threat as far back as 2007, when it was still being planned. NATO says the shield is purely defensive. Military sources told Reuters the system in Poland can now only be used against missiles fired from the Middle East and the radar would need a change in direction to intercept projectiles from Russia, a complex procedure entailing a change of policy. Polish Defense Minister Wladyslaw Kosiniak-Kamysz said on Monday the scope of the shield needed to be expanded, which Warsaw would discuss with NATO and the United States. NATO Secretary General Mark Rutte will meet Duda and Prime Minister Donald Tusk in Warsaw later on Wednesday. Full Article Europe
sign Tantalizer Plc names new board after significant acquisition by new shareholders By hallmarknews.com Published On :: Wed, 13 Nov 2024 07:18:02 +0000 Tantalizer Plc has notified the Nigerian Exchange (NGX) of the recent changes to its Board of Directors Arising from the Private Placement and the subsequent majority shareholding acquired by both Messrs Food Specialties and Organics Limited and Banklink Africa Private Equities Limited, a Board meeting was convened on 15th October, 2024. During this meeting, decisions […] The post Tantalizer Plc names new board after significant acquisition by new shareholders first appeared on Business Hallmark. Full Article Business Tantalizer Tantalizer Plc names new board after significant acquisition by new shareholders
sign UNHRC calls for significant legal reforms to uphold human rights in Pakistan By www.iol.co.za Published On :: Wed, 13 Nov 2024 18:06:35 GMT Full Article
sign Nigeria: NNPC Subsidiary Signs Gas Sale, Supply Agreement With Dangote Refinery By allafrica.com Published On :: Thu, 14 Nov 2024 05:43:08 GMT [Leadership] The NNPC Gas Marketing Limited (NGML), a subsidiary of the Nigerian National Petroleum Company Limited (NNPCL), has successfully executed a Gas Sale and Purchase Agreement (GSPA) with Dangote Petroleum Refinery and Petrochemicals FZE. Full Article Economy Business and Finance Energy Nigeria Petroleum West Africa
sign Kenya: U.S. Ambassador Resigns Amid 'Sustained Pressure' On Social Media By allafrica.com Published On :: Wed, 13 Nov 2024 16:04:01 GMT [Capital FM] NAIROBI -- United States Ambassador to Kenya, Meg Whitman has announced her resignation after two years of being stationed in Kenya. Full Article East Africa External Relations Kenya United States Canada and Africa
sign PTA signals further VPN curbs By www.dawn.com Published On :: Thu, 14 Nov 2024 11:22:14 +0500 ISLAMABAD: Following a disruption that rendered virtual private networks (VPNs) dysfunctional across the country, the Pakistan Telecommunication Authority (PTA) on Wednesday said that VPN usage would be restricted in the future to curb access to pornographic content. In a statement, the authority claimed it had so far blocked 100,183 URLs containing blasphemous content, as well as 844,008 pornographic websites. The statement by PTA highlighting its performance came a day after the Ministry of Religious Affairs and Interfaith Harmony wrote to the regulator to ask it to block blasphemous and pornographic content. “In addition to PTA’s proactive efforts, individuals and government organisations also report such sites,” the statement added. The telecom regulator also claimed that approximately 20 million attempts were made from within the country to access pornographic websites on a daily basis, which were blocked at the international gateway level. “However, users bypass restrictions via VPNs and access porn contents, PTA remains fully committed to curbing this issue, taking all necessary measures to block this content effectively,” the statement added. In another statement, the telecom regulator said it had organised a consultation on the issue of VPN use, attended by representatives from the Ministry of IT & Telecommunication (MoIT&T), the Pakistan Software Export Board (PSEB), and the Pakistan Software Houses Association (P@SHA). “The PTA introduced a streamlined VPN registration process, allowing legitimate users to register their VPNs through a new online portal at ipregistration.pta.gov.pk,” the statement said. However, a senior executive from an internet service provider — in response to a Dawn query — said the authority was “making excuses”. “How would they know that people are watching porn through VPNs? They have no capability to [monitor traffic through] VPNs, otherwise they would not block it,” the executive said. He said the main target was blocking access to X and other social media platforms. Published in Dawn, November 14th, 2024 Full Article Tech
sign Matt Gaetz resigns from Congress 'effective immediately' following attorney-general nomination By www.washingtontimes.com Published On :: Wed, 13 Nov 2024 19:47:58 -0500 House Speaker Mike Johnson announced that Rep. Matt Gaetz, who was tapped by President-elect Donald Trump to run the Justice Department, issued his resignation letter on Wednesday. Full Article
sign Matt Gaetz resigns from Congress over Trump nod to be attorney general, Johnson says By www.foxnews.com Published On :: Wed, 13 Nov 2024 19:15:13 -0500 Rep. Matt Gaetz is out of Congress, Speaker Johnson said, after he was tapped to be the next attorney general. Full Article a7a32ed4-7479-5a95-9d7d-111695fc060b fnc Fox News fox-news/politics/elections/presidential/trump-transition fox-news/politics/executive/cabinet fox-news/politics/house-of-representatives fox-news/politics fox-news/politics article
sign Archbishop of Canterbury’s resignation ‘won’t fix the problem’, says Bishop of Dover on church abuse scandal By www.channel4.com Published On :: We spoke to the Bishop of Dover, Rose Hudson-Wilkin from Canterbury. Full Article
sign Archbishop of Canterbury resigns after church abuse scandal By www.channel4.com Published On :: Justin Welby hasn’t said when he’ll go. But replacing him won’t be easy. Victims of decades of church abuse are calling for root and branch reform. Full Article
sign Horoscope 14th November, 2024: Check astrological prediction for Virgo, Sagittarius and other signs - The Indian Express By news.google.com Published On :: Wed, 13 Nov 2024 19:30:07 GMT Horoscope 14th November, 2024: Check astrological prediction for Virgo, Sagittarius and other signs The Indian ExpressHoroscope Today: November 14, 2024 VOGUE IndiaLove and Relationship Horoscope for November 14, 2024 Hindustan TimesHoroscope Today, November 14, 2024: Read your today's astrological predictions The Times of IndiaAries Daily Horoscope Today (Mar 21 – April 19), November 14, 2024: Relationships will be comfortable! India Today Full Article
sign Bluesky surges to 15 million users after getting a million sign-ups in one week By www.engadget.com Published On :: Wed, 13 Nov 2024 22:42:13 +0000 Bluesky may still be the underdog in the race for alternatives to X, but the once Twitter-affiliated service is gaining momentum. The app just passed the 15 million user mark after adding more than a million new users over the last week, the company said in an update. While Bluesky is still considerably smaller than Threads, which with 275 million users is its biggest rival, there are signs that Threads users have been increasingly curious about the upstart. “Bluesky” has been a trending topic on Threads in recent days and an in-app search suggestion shows there are more than 19,000 posts about “Bluesky.” Bluesky itself has also made a push to win over Threads users in recent weeks by posting regularly on the Meta-owned service. That effort seems to be working. A month ago, Engadget noted, the service had just under 9 million users. Its mobile app also has the top spot in Apple’s App Store, followed by Threads and ChatGPT. Its recent success also seems to be driven, at least in part, by frustration with Elon Musk and X following the US presidential election. A recent report from web analytics company SimilarWeb found that “more than 115,000 US web visitors deactivated their accounts,” on November 7, “more than on any previous day of Elon Musk’s tenure.” The report also noted that “web traffic and daily active users for Bluesky increased dramatically in the week before the election, and then again after election day,” with Bluesky at points seeing more web traffic than Threads. (Threads’ mobile usage, however, is still “far ahead” of Bluesky.) SimilarWeb “In the US, Bluesky got more web visits than Threads in the immediate aftermath of the election,” the report notes. “For context, it’s important to note that both services are app centric, even though they support a web user interface.” On its part, Bluesky seems intent on distinguishing itself from its larger, billionaire-controlled rivals. The company, which began as an internal project at Twitter before it spun off into an independent entity, has experimented with novel features like custom feeds, user-created moderation services and “starter packs” for new users. “You're probably used to being trapped in a single algorithm controlled by a small group of people, that's no longer the case,” Bluesky’s COO Rose Wang shared in a video aimed at new users Tuesday. “On Bluesky, there are about 50,000 different feeds … these feeds provide a cozy corner for you to meet people with similar interests. And you can actually make friends again, because you're no longer tied to a dominant algorithm that promotes either the most polarizing posts and or the biggest brands, and that's the mandate of Bluesky.”This article originally appeared on Engadget at https://www.engadget.com/social-media/bluesky-surges-to-15-million-users-after-getting-a-million-sign-ups-in-one-week-224213573.html?src=rss Full Article Software Technology & Electronics site|engadget provider_name|Engadget region|US language|en-US author_name|Karissa Bell
sign 'You didn't sign up to be a hotel': Free-spirit couple with 5 and 7-year-old kids sells their home to take "extended vacation," begs brother for help By cheezburger.com Published On :: Wed, 13 Nov 2024 12:00:00 -0800 If you suddenly showed up at your sibling's home and asked to live with them for 10 months, it would make things awkward, that's for certain. You can't just ask someone to live with them for that long without having a big discussion about what it would mean for you both. And this woman isn't just asking her brother to stay there alone… she wants to bring her entire family, including her two young children. While we always want to be there for the family members we adore, living with someone is a whole other ball game. This guy has his own home that he's spent a decade paying off. Now suddenly, his younger sister is begging to move in with him because of her own ill-fated adventures. She was living the dream: she sold her family's home in order to travel full-time. While many of us dream of doing things like that, there's a reason most people can't. It's just too expensive to maintain. The sister found this out within just two months of her perma-vacation… but should her brother really be expected to house his sister just because she intentionally chose to give up her house? Check out the full story below and see if you agree with commenters telling this guy to avoid housing her and possibly even cut her off. Up next, read about the drama that one stage mom started when she decided to divorce her long-distance husband over email, while also CC'ing his entire family, friend group, and workplace. Full Article family drama housing aita kids brother house Travel family sister
sign Open Cardiography Signal Measuring Device By hackaday.com Published On :: Thu, 14 Nov 2024 00:00:23 +0000 Much of the world’s medical equipment is made by a handful of monopolistic megacorps, but [Milos Rasic] built an open cardiography signal measuring device for his master’s thesis. Using a …read more Full Article Medical Hacks blood pressure electrocardiogram electrocardiography pulse oximeter Pulse oximetry stethoscope
sign Accor Drives Asia Expansion with 27 New Hotel Signings in 2024 By www.hospitalitynet.org Published On :: Wed, 13 Nov 2024 13:21:15 +0200 Accor, a global leader in hospitality, is accelerating the Group’s growth in Asia securing 27 hotel signings and 8,117 keys year-to-date. The expansion encompasses twelve brands throughout eight countries, from India to South Korea and Japan. Full Article
sign Orient Express Corinthian Unveils Its Design and Interiors in All Their Splendour By www.hospitalitynet.org Published On :: Wed, 13 Nov 2024 12:06:53 +0200 The first of the two Orient Express yachts, will set sail in June 2026 to cruise the Mediterranean, Adriatic and Caribbean seas. Full Article
sign Design Hotels Releases Further Forecast Trend Report, Seeing Demand for Community Drive the Future of Travel By www.hospitalitynet.org Published On :: Wed, 13 Nov 2024 17:12:40 +0200 Design Hotels, the community-driven portfolio of nearly 300 independent hotels, today announced its second annual Further Forecast trend report, which explores travelers’ growing desire to build deeper connections, and how this is shaping their expectations of experiences—and in turn, the future of travel. Full Article
sign World Diabetes Day 2024: Top 5 Early Warning Signs of High Blood Sugar Levels That Appear In Morning - TheHealthSite By news.google.com Published On :: Thu, 14 Nov 2024 04:25:00 GMT World Diabetes Day 2024: Top 5 Early Warning Signs of High Blood Sugar Levels That Appear In Morning TheHealthSiteTackling diabetes epidemic The HinduWorld Diabetes Day 2024: Why type 2 diabetes often goes unnoticed, early signs of this silent killer, and associated risks The Economic TimesWorld Diabetes Day 2024 PIB86% diabetics in India facing anxiety, depression; women more affected: Report Gujarat Samachar Full Article
sign Indian Embassy in Kathmandu calls on diaspora to sign-up for Pravasi Bharatiya Divas Convention of January By www.newkerala.com Published On :: Wed, 13 Nov 2024 13:46:03 +0530 Full Article
sign AP govt signs MoU worth Rs 65,000 cr with Reliance Industries for investment in CBG projects By www.newkerala.com Published On :: Wed, 13 Nov 2024 19:48:02 +0530 Full Article
sign [LINK] A new design for Mark Boulton By www.markboulton.co.uk Published On :: 2010-11-30T13:17:08+00:00 Words to tattoo on your knuckles: Over the past couple of years, my blog hasn’t felt my own, to a degree. It’s felt like I’ve been writing for an audience, posting stuff for others rather than myself. That’s arse-backwards. A blog should be about personal expression. The moment you start thinking, and writing, to please others then it’s a bind; it feels less like a personal exercise and more of a job. A beautiful, thoughtful redesign from Mark Boulton (and a responsive one at that). Go go, read read. ∞ Full Article
sign Design of Interfacial Dual Schottky Junctions to Modulate Charge Transfer for Enhanced Piezo-assisted Photocatalytic Degradation RhB Performances By pubs.rsc.org Published On :: J. Mater. Chem. A, 2024, Accepted ManuscriptDOI: 10.1039/D4TA00619D, PaperXiaoqi Jiang, Shengdong Sun, Yuqiao Wang, Lebing Zhao, Fangzhi Huang, Shikuo LiRegulating charge transfer is a great challenge to improving the efficiency of piezoelectric photocatalytic reactions. Herein, sandwich-like Bi2WO6@Ag/MXene nanoflower spheres (BWO@Ag/MXene) with piezoelectric/plasma dual characteristics were synthesized by a facile...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Bio-inspired design of a self-supported bismuth microforest for high performance sodium storage By pubs.rsc.org Published On :: J. Mater. Chem. A, 2024, Advance ArticleDOI: 10.1039/D4TA00950A, PaperJia Bai, Yan Liu, Ben Pu, Qi Tang, Yongbin Wang, Ruihan Yuan, Jin Cui, Yi Yang, Xiaojia Zheng, Bin Zhou, Weiqing YangA self-supported bismuth microforest anode material, prepared by a simple, efficient and scalable in situ galvanic replacement approach, exhibits high performance for sodium-ion batteries.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign India among top 10 countries in patents, trademarks, and industrial designs: WIPO 2024 report By www.newkerala.com Published On :: Wed, 13 Nov 2024 17:58:02 +0530 Full Article
sign Gaining the Molecular Design Principles for Efficient Diarylethene Photoacid and Photohydride Generators Based on Photochemical Reaction Mechanism By pubs.rsc.org Published On :: Chem. Sci., 2024, Accepted ManuscriptDOI: 10.1039/D4SC06202G, Edge Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yifan Su, Dexin Zheng, Lingfeng Ge, Le Yu, David Lee Phillips, Jiani Ma, Yu FangAbstract: Photoacid generators (PAGs) and photohydride generators (PHGs) are specific photolabile protecting groups that release acid and hydride, respectively. Over the past decade, great efforts have been devoted to developing...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Indonesia and Australia hold joint military drills after signing a new defense agreement By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:32:15 +0530 The Indonesian and Australian militaries are holding joint combat drills off Indonesia’s main island of Java with about 2,000 troops training in air, maritime, amphibious and land operations Full Article World
sign Furoxan–piplartine hybrids as effective NO donors and ROS inducers in PC3 cancer cells: design, synthesis, and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3778-3794DOI: 10.1039/D4MD00281D, Research ArticleCarolyne Brustolin Braga, Julio Cesar Milan, Matheus Andrade Meirelles, Bruno Zavan, Guilherme Álvaro Ferreira-Silva, Ester Siqueira Caixeta, Marisa Ionta, Ronaldo A. PilliA novel hybrid integrating piplartine with a furoxan moiety exhibited a sub-micromolar IC50 and extraordinary selectivity for PC3 cells, which was associated with its capacity to release NO, generate ROS, induce DNA damage, and trigger apoptosis.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Design and synthesis of novel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3800-3816DOI: 10.1039/D4MD00585F, Research ArticleMarwa Abdel-Motaal, Dalal Ali Aldakhili, Ayman B. Farag, Ayman Abo Elmaaty, Marwa Sharaky, Nadia A. Mohamed, Saad Shaaban, Abdullah Yahya Abdullah Alzahrani, Ahmed A. Al-KarmalawyNovel multi-target tetrabromophthalimides as CBS and Topo-II inhibitors and DNA intercalators.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Asymmetric imidazole-4,5-dicarboxamide derivatives as SARS-CoV-2 main protease inhibitors: design, synthesis and biological evaluation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3880-3888DOI: 10.1039/D4MD00414K, Research ArticlePhuong Nguyen Hoai Huynh, Phatcharin Khamplong, Minh-Hoang Phan, Thanh-Phuc Nguyen, Phuong Ngoc Lan Vu, Quang-Vinh Tang, Phumin Chamsodsai, Supaphorn Seetaha, Truong Lam Tuong, Thien Y. Vu, Duc-Duy Vo, Kiattawee Choowongkomon, Cam-Van T. VoNovel asymmetric imidazole-4,5-dicarboxamide derivatives were synthesized, evaluated for SARS-CoV-2 MPro inhibitory activity in vitro, and investigated for binding ability in silico.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Novel PROTAC probes targeting KDM3 degradation to eliminate colorectal cancer stem cells through inhibition of Wnt/β-catenin signaling By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3746-3758DOI: 10.1039/D4MD00122B, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Shadid U. Zaman, Piyusha P. Pagare, Hongguang Ma, Rosalie G. Hoyle, Yan Zhang, Jiong LiWe designed and synthesized novel IOX1-based PROTACs, which can selectively degrade KDM3A and KDM3B to eliminate colorectal cancer stem cells through inhibition of Wnt signaling.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3862-3879DOI: 10.1039/D4MD00313F, Research ArticleDaniele Pala, David Clark, Christine Edwards, Elisa Pasqua, Laura Tigli, Barbara Pioselli, Piotr Malysa, Fabrizio Facchinetti, Fabio Rancati, Alessandro AccettaThis study reports a novel, potent and selective series of ROCK inhibitors based on 8-(azaindolyl)-benzoazepinones identified through a core-hopping strategy.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3912-3912DOI: 10.1039/D4MD90040E, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Nilesh Raghunath Khedkar, Milind Sindkhedkar, Alex JosephThe content of this RSS Feed (c) The Royal Society of Chemistry Full Article
sign Pact for third ro-ro vessel of Kochi Corporation signed By www.thehindu.com Published On :: Wed, 13 Nov 2024 21:24:39 +0530 The third vessel will serve as a standby for the two vessels that are owned by Kochi Corporation Full Article Kochi
sign No roadmap yet for better traffic signage system in Kozhikode city By www.thehindu.com Published On :: Wed, 13 Nov 2024 23:33:12 +0530 Emergency signboards and lane markings near roundabouts have not yet been introduced to streamline the traffic management Full Article Kerala
sign This week's sponsor: O’REILLY DESIGN CONFERENCE By synd.co Published On :: 2016-11-28T05:01:00+00:00 O’REILLY DESIGN CONFERENCE - get the skills and insights you need to design the products of the future. Save 20% with code ALIST Full Article
sign Element and isotopic signature of re-fertilized mantle peridotite as determined by nanopowder and olivine LA-ICPMS analyses By geoscan.nrcan.gc.ca Published On :: Thu, 09 Jan 2020 00:00:00 EDT Lawley, C J M; Pearson, D G; Waterton, P; Zagorevski, A; Bédard, J H; Jackson, S E; Petts, D C; Kjarsgaard, B A; Zhang, S; Wright, D. Chemical Geology vol. 536, 119464, 2020 p. 1-17, https://doi.org/10.1016/j.chemgeo.2020.119464<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20190600.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20190600.jpg" title="Chemical Geology vol. 536, 119464, 2020 p. 1-17, https://doi.org/10.1016/j.chemgeo.2020.119464" height="150" border="1" /></a> Full Article
sign Tectonic significance of the Virgin River shear zone of the Canadian Shield and implications for the origin of the Snowbird tectonic zone of Laurentia By geoscan.nrcan.gc.ca Published On :: Tue, 25 May 2021 00:00:00 EDT Card, C D; Bethune, K M; Rayner, N; Ashton, K E. Precambrian Research vol. 361, 106241, 2021 p. 1-22, https://doi.org/10.1016/j.precamres.2021.106241<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20210185.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20210185.jpg" title="Precambrian Research vol. 361, 106241, 2021 p. 1-22, https://doi.org/10.1016/j.precamres.2021.106241" height="150" border="1" /></a> Full Article
sign Paleoenvironmental analyses and revised lithostratigraphic assignments for 28 wells of the Hopedale and Saglek basins, offshore eastern Canada By geoscan.nrcan.gc.ca Published On :: Wed, 14 Jul 2021 00:00:00 EDT Dafoe, L T. Geological Survey of Canada, Open File 8810, 2021, 209 pages (28 sheets), https://doi.org/10.4095/328477<a href="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328477.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/gid_328477.jpg" title="Geological Survey of Canada, Open File 8810, 2021, 209 pages (28 sheets), https://doi.org/10.4095/328477" height="150" border="1" /></a> Full Article
sign Regional stagnation of the western Keewatin ice sheet and the significance of meltwater corridors and eskers, northern Canada By geoscan.nrcan.gc.ca Published On :: Wed, 07 Apr 2021 00:00:00 EDT Sharpe, D R; Lesemann, J -E; Knight, R D; Kjarsgaard, B A. Canadian Journal of Earth Sciences vol. 58, issue 10, 2021 p. 1-22, https://doi.org/10.1139/cjes-2020-0136<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200745.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200745.jpg" title="Canadian Journal of Earth Sciences vol. 58, issue 10, 2021 p. 1-22, https://doi.org/10.1139/cjes-2020-0136" height="150" border="1" /></a> Full Article
sign Assessment of the Amaruq gold deposit signature in glacial sediments using multivariate geochemical data analysis and indicator minerals By geoscan.nrcan.gc.ca Published On :: Fri, 07 May 2021 00:00:00 EDT de Bronac de Vazelhes, V; McMartin, I; Côté-Mantha, O; Boulianne-Verschelden, N. Journal of Geochemical Exploration vol. 228, 106800, 2021 p. 1-17, https://doi.org/10.1016/j.gexplo.2021.106800<a href="https://geoscan.nrcan.gc.ca/images/geoscan/20200684.jpg"><img src="https://geoscan.nrcan.gc.ca/images/geoscan/20200684.jpg" title="Journal of Geochemical Exploration vol. 228, 106800, 2021 p. 1-17, https://doi.org/10.1016/j.gexplo.2021.106800" height="150" border="1" /></a> Full Article
sign Cordilleran magmatism in Yukon and northern British Columbia: characteristics, temporal variations, and significance for the tectonic evolution of the northern Cordillera By geoscan.nrcan.gc.ca Published On :: Thu, 25 Nov 2021 00:00:00 EDT Zagorevski, A; van Staal, C R. Northern Cordillera geology: a synthesis of research from the Geo-mapping for Energy and Minerals program, British Columbia and Yukon; by Ryan, J J (ed.); Zagorevski, A (ed.); Geological Survey of Canada, Bulletin 610, 2021 p. 95-122, https://doi.org/10.4095/326063 Full Article
sign Overview of Cordilleran oceanic terranes and their significance for the tectonic evolution of the northern Cordillera By geoscan.nrcan.gc.ca Published On :: Thu, 25 Nov 2021 00:00:00 EDT Zagorevski, A; van Staal, C R; Bédard, J H; Bogatu, A; Canil, D; Coleman, M; Golding, M; Joyce, N L; Lawley, C; McGoldrick, S; Mihalynuk, M G; Milidragovic, D; Parsons, A; Schiarizza, P. Northern Cordillera geology: a synthesis of research from the Geo-mapping for Energy and Minerals program, British Columbia and Yukon; by Ryan, J J (ed.); Zagorevski, A (ed.); Geological Survey of Canada, Bulletin 610, 2021 p. 21-65, https://doi.org/10.4095/326053 Full Article