A multidisciplinary committee representing 11 nations will plan the Third International Summit on Human Genome Editing, to be held in London March 7-9, 2022. The NAS and NAM join other international partners in organizing the summit, which will build upon previous events held in Washington, D.C. and Hong Kong.

Registration is now open for the Third International Summit on Human Genome Editing, to be held March 6-8, 2023, in London. The three-day summit is being organized by the Royal Society and U.K. Academy of Medical Sciences, the U.S. National Academy of Sciences and National Academy of Medicine, and the World Academy of Sciences.

The final agenda is now available for the Third International Summit on Human Genome Editing, to be held March 6-8 in London and virtually. The National Academy of Sciences and National Academy of Medicine are among the international partners hosting the summit.

EPFL scientists have carried out a genomic and evolutionary study of a large and enigmatic family of human proteins, to demonstrate that it is responsible for harnessing the millions of transposable elements in the human genome. The work reveals the largely species-specific gene-regulatory networks that impact all of human biology, in both health and disease.

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Fintech applications have simplified purchasing and put financial independence at everyone’s fingertips, challenging the traditional banking and lending system.

We were born from the need to create a quality apparel brand whose designs scream a love for sneakers, and whose collections are the completion of every sneakerhead's wardrobe.

We have all heard of the use of Botox injections for cosmetic purposes...but how can they be helpful for our feet?

By Gerald E. Ulen Discover the Hidden Realms of Electricity with Gerald E. Ulen's Upcoming Release

In-depth guide to genotyping complex genomes By their very nature complex genomes are complex to analyse. This new ebook looks at different ways of tacklin

In-depth guide to genotyping complex genomes By their very nature complex genomes are complex to analyse. This new ebook looks at different ways of tacklin

TORONTO, ON — Researchers from the University of Toronto and SickKids Research Institute announced today that they have successfully mapped the genes in the fungus that causes Dutch Elm Disease. The researchers believe this is the first time the 30 million DNA letters for the fungus Ophiostoma ulmi have been mapped. The findings, published in […]

The device measures pressure, temperature, flow, and other parameters. Five different ranges are available from ±30 inches of water column to ±100 psi.

Posted by Alan Coopersmith on Nov 12

In addition to the known phenomena of lightning and switching, numerous new sources, in particular power converters, can cause disturbance in installations. This disturbance, which is generated by the installation itself or carried by the system from external sources or... Read more

The post Six less known phenomena that can cause disturbance in electrical installations appeared first on EEP - Electrical Engineering Portal.

Parallel switching occurs when two or more circuit-breakers are tripped to interrupt a shared fault current. This is typically the case for such bus arrangements as a double breaker, breaker-and-a-half, breaker-and-a-third, and ring buses. Ideally, all of the circuit-breakers should... Read more

The post Parallel switching phenomenon when MV/HV circuit breakers interrupt a shared fault current appeared first on EEP - Electrical Engineering Portal.

Nomenclature of the frequency and wavelength bands used in telecommunications

Nomenclature of the frequency and wavelength bands used in telecommunications

Test signals for use in telephonometry

NTT DATA, the IT services provider and industry consultancy, has announced the end of a project that used quantum computing to optimise genome assembly processes. This is claimed to be a milestone in the use of this technology in the Healthcare and Life Sciences industries.

Astronomers may have discovered the first planet outside of our galaxy

But only in the event of a warp-drive equivalent to a space shuttle disaster.

Astronomers have, for the first time, mapped the 3D filamentary structure of a famous dandelion-shaped supernova remnant.

The post Astronomers Map a Dandelion Supernova appeared first on Sky & Telescope.

Library - Art Library, Location - LIB, Call number - N6512.75.W66 E97 2016

Location: Electronic Resource- 

Location: Engineering Library- TA455.P58V65 2016

Location: Engineering Library- TJ853.4.M53P36 2016

For the past decade, scientists have relied almost exclusively on CRISPR-Cas systems for genome editing. Now, a smaller but equally efficient nuclease is here to compete. 

I checked in with management and apparently we have to do a 2022 now even though we just finished wiht 2021. Jessamyn and I do our best to roll into the new year and talk about MetaFilter stuff and get in a philosophical discussion of the nature of the literal horizon qua solar objects. Runs about 90 minutes.

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In celebration of World Oceans Day, BioQuest announced it has “officially completed the draft reference genome of the Grooved Brain Coral, marking the first-time whole genome sequencing of a coral reef has been accomplished in the Caribbean by the Caribbean.” A spokesperson said, “This groundbreaking work was conducted locally in Bermuda in collaboration with the […]

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Today’s methods for computing orientation are quaternion and rotation matrix. However, their efficiencies are tarnished by the complexity of the rotation matrix and the counterintuitivity of quaternion. A better method is presented here. It uses complex multiplication for rotating vectors in 3D space and can compute orientation without angle and trigonometric functions, which is simple,...

The post Rare Natural Phenomenon Observed in Saint Petersburg appeared first on English Russia.

The exoplanet candidate is about the size of Saturn and located in a Whirlpool galaxy system 28 million light-years from Earth.

An international research team used Hubble, TESS, and other instruments to witness the “Rosetta Stone” of supernovas. Its findings could help astronomers predict when other stars in the universe are about to explode.

Two hours before asteroid 2022 EB5 entered Earth’s atmosphere, scientists knew exactly when and where the space rock would strike.

The director of Collective Phenomena, Semion Aleksandrovskiy, shared a little of this complex history via his own family story.

Linn Fagerberg
Feb 1, 2014; 13:397-406
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Alison M. Kurimchak
Dec 1, 2020; 19:2068-2089
Research

Gerhard Liebisch
Dec 1, 2020; 61:1539-1555
Special Report

A comprehensive and standardized system to report lipid structures analyzed by MS is essential for the communication and storage of lipidomics data. Herein, an update on both the LIPID MAPS classification system and shorthand notation of lipid structures is presented for lipid categories Fatty Acyls (FA), Glycerolipids (GL), Glycerophospholipids (GP), Sphingolipids (SP), and Sterols (ST). With its major changes, i.e., annotation of ring double bond equivalents and number of oxygens, the updated shorthand notation facilitates reporting of newly delineated oxygenated lipid species as well. For standardized reporting in lipidomics, the hierarchical architecture of shorthand notation reflects the diverse structural resolution powers provided by mass spectrometric assays. Moreover, shorthand notation is expanded beyond mammalian phyla to lipids from plant and yeast phyla. Finally, annotation of atoms is included for the use of stable isotope-labeled compounds in metabolic labeling experiments or as internal standards. This update on lipid classification, nomenclature, and shorthand annotation for lipid mass spectra is considered a standard for lipid data presentation.

Endometrial carcinoma (EC) is the most common gynecologic malignancy in the United States, with limited effective targeted therapies. Endometrial tumors exhibit frequent alterations in protein kinases, yet only a small fraction of the kinome has been therapeutically explored. To identify kinase therapeutic avenues for EC, we profiled the kinome of endometrial tumors and normal endometrial tissues using Multiplexed Inhibitor Beads and Mass Spectrometry (MIB-MS). Our proteomics analysis identified a network of kinases overexpressed in tumors, including Serine/Arginine-Rich Splicing Factor Kinase 1 (SRPK1). Immunohistochemical (IHC) analysis of endometrial tumors confirmed MIB-MS findings and showed SRPK1 protein levels were highly expressed in endometrioid and uterine serous cancer (USC) histological subtypes. Moreover, querying large-scale genomics studies of EC tumors revealed high expression of SRPK1 correlated with poor survival. Loss-of-function studies targeting SRPK1 in an established USC cell line demonstrated SRPK1 was integral for RNA splicing, as well as cell cycle progression and survival under nutrient deficient conditions. Profiling of USC cells identified a compensatory response to SRPK1 inhibition that involved EGFR and the up-regulation of IGF1R and downstream AKT signaling. Co-targeting SRPK1 and EGFR or IGF1R synergistically enhanced growth inhibition in serous and endometrioid cell lines, representing a promising combination therapy for EC.

Nov. 11, 2024 — A team of researchers used the Frontier supercomputer at the Department of Energy’s Oak Ridge National Laboratory and a new methodology for conducting a genome-wide association […]

The post ORNL’s Frontier Powers KAUST-Led Genome Study for Gordon Bell Prize Nomination appeared first on HPCwire.

In 1925, an Alaskan adventurer and his trusted Siberian husky completed a grueling 600-mile journey across the frozen plains. Their exploits would end up saving the lives of 2,000 people.

This video from the Illustris project simulates 13 billion years of the universe in just two minutes

The energetic streams are together 23 million light-years in length—roughly as long as 140 Milky Way galaxies lined end to end

Scientists have created "a form of information immortality" meant to instruct future species on how to recreate humans. But who, or what, will find it?

A roughly 33-foot-long asteroid called 2024 PT5 will chart a horseshoe-like path around our planet

Orbiting Barnard's star, the nearest solo star to Earth, the world is too hot to be habitable—a scorching 257 degrees Fahrenheit