The Court of Appeal has today cast doubt on existing domestic case-law on when the obligation to consult begins under section 188 TULRCA and the EU Collective Redundancies Directive. Having considered two opposing views as to when consultation begin...

In

Following the outcome of a Government consultation paper, the full force of the Consumer Rights Act 2015 (CRA) will apply to the aviation sector as from the 1 October 2016. The result could lead to compensation being paid up to the price of the air ...

Cohesin is a ring-shaped multiprotein complex that is crucial for 3D genome organization and transcriptional regulation during differentiation and development. It also confers sister chromatid cohesion and facilitates DNA damage repair. Besides its core subunits SMC3, SMC1A, and RAD21, cohesin in somatic cells contains one of two orthologous STAG subunits, STAG1 or STAG2. How these variable subunits affect the function of the cohesin complex is still unclear. STAG1- and STAG2-cohesin were initially proposed to organize cohesion at telomeres and centromeres, respectively. Here, we uncover redundant and specific roles of STAG1 and STAG2 in gene regulation and chromatin looping using HCT116 cells with an auxin-inducible degron (AID) tag fused to either STAG1 or STAG2. Following rapid depletion of either subunit, we perform high-resolution Hi-C, gene expression, and sequential ChIP studies to show that STAG1 and STAG2 do not co-occupy individual binding sites and have distinct ways by which they affect looping and gene expression. These findings are further supported by single-molecule localizations via direct stochastic optical reconstruction microscopy (dSTORM) super-resolution imaging. Since somatic and congenital mutations of the STAG subunits are associated with cancer (STAG2) and intellectual disability syndromes with congenital abnormalities (STAG1 and STAG2), we verified STAG1-/STAG2-dependencies using human neural stem cells, hence highlighting their importance in particular disease contexts.

Follow our live coronavirus updates here Coronavirus: the symptoms

British Airways is set to make up to 12,000 workers redundant, its parent company has said.

More than 1,000 British Airways pilots are set to lose their jobs as part of major redundancy plans announced by the airline, it is reported.

Redundancy can come about at anytime but you can safeguard against the unknown as well as the reality that it could possibly occur to you. Income protection insurance would let you take out a policy to get a fixed premium every month...

New Zealand should extend access to income support and introduce a longer minimum notice period for all workers to help disadvantaged laid-off workers find a new job and maintain their job quality and living standards, according to a new OECD report.

PETE JENSON IN SPAIN: If Barcelona are the club most struggling with the financial consequences of the Coronavirus because of their huge over-spend, Atletico Madrid are not far behind them.

The former Love Island star, 27, worked as an air hostess for the company prior to finding fame on the ITV2 reality series.

People aged 39-54 who suffered compulsory redundancy have average pensions savings of £120,634 - while those who avoided being laid off have £202,017.

We explain how you can mitigate the fallout from reducing or ending pension contributions for a time. Don't panic, stay vigilant against scams, and keep paying in if you can afford it.

Up to a quarter of British Airways' 45,000 workers could lose their jobs as its owners IAG announced mass redundancies on Tuesday afternoon. Owners IAG blamed the impact of the Covid-19 pandemic.

Coronavirus has wiped out demand and IAG believes it will take several years for air travel to recover to 2019 levels.

Bosses at the company's owner, Barings Asia, are withholding the severance payment. Instead staff have been been told to apply for government handouts.

Currently, employees do not have to pay income tax or national insurance if their redundancy pay is under £30,000.

Online Resource

IEEE / Institute of Electrical and Electronics Engineers Incorporated

Online Resource

Given the government’s extensive requests on avoiding laying off employees, the majority of companies have not implemented or are not currently considering permanent staff layoff/redundancies (84%) or temporary layoff/furlough (83% without government subsidy support and 91% leveraging government subsidy).