Delta says the faulty update cost the airline at least $500 million in out-of-pocket losses — in addition to “severe harm to its reputation and goodwill,” according to the complaint, filed Friday in state court in Georgia

Produced by WIRED Brand Lab in partnership with Wilderness | The Okavango Delta in Botswana shelters endangered species amidst threats to its delicate ecosystem. Join WIRED Brand Lab's Marcus Jones on a journey to explore Wilderness Mombo —a pioneering safari lodge using technology for sustainability and wildlife preservation across its 45,000-hectare home, harmonizing with the wilderness for an eco-conscious future.

Branded Content by Delta Air Lines | Imagine an in-flight experience tailored just for you. Delta Air Lines is pioneering personalized entertainment solutions, from resuming films on connecting flights to delivering luggage status updates on your screen. Tech journalist Saira Mueller and Delta’s Managing Director of Customer Experience, Ekrem Dimbiloglu, sit down to discuss how Delta is transforming its service to offer a truly customized travel experience.

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The Penn State DuBois Delta Mu Sigma Honor Society has announced award winners for the 2019-20 academic year.

THERE were mixed reactions, last week, over the transfer of 62 southern police officers from the ranks of Superintendent of Police, SP, to Chief Superintendent of Police, CSP, and including 15 Divisional Police Officers, DPOs, from Delta State Police Command to the northern part of the country.

The post AMID SUSPECTED HERDSMEN ATTACKS: Storm in Delta over mass transfer of police officers appeared first on Vanguard News.

The wet and verdant expanse of the Mekong Delta’s rivers and farms is a veritable rice bowl for the world. Not only do the region’s paddies produce half of Viet Nam’s rice crop yearly, the country is the world’s third largest rice exporter, with 17% of world exports of paddy rice. Our analysis identifies Viet Nam as facing the world’s fourth highest water risks for rice production.

Ancient pollen and charcoal preserved in deeply buried sediments in Egypt’s Nile Delta document the region’s ancient droughts and fires, including a huge drought 4,200 years ago associated with the demise of Egypt’s Old Kingdom.

The post Fossil pollen used to augment climate record of Egypt’s Nile Delta appeared first on Smithsonian Insider.

Why not take this opportunity to view six other meteor showers this summer?

Video: Alexandra Cousteau and Expedition Blue Planet follow Colorado's dry riverbed to its historic mouth in the Upper Gulf of California.

Our Value Design Products Increase the Value of Your Control Panels. Set two time ranges between 1 and 120 s with one Timer.(H3DT-G)

Advanced Interconnect Test Tool (AITT) Makes SI Analysis Easy

Preferred Market Solutions, LLC, is fast approaching its two-year anniversary of powering Delta Bingo & Gaming's InnerCircle Rewards program.

One might think to themselves "Are these fixes necessary? Are these prices too high?" There may not be a way to avoid automotive repairs entirely, but there is a way to stay in control of the situation.

The feeling of uncertainty about which auto repair mechanic to use is very common. The following points will assist you in making the right decision.

Cleaning off all of the salt and dirt will help keep your car looking fresh, but with only a little more work you can make sure that your car will be running well too.

We here at Delta Auto Protect see our fair share of car trouble that could have been prevented with a bit of routine maintenance, so we put together this list of maintenance tips that can prevent your car from any unnecessary trips to the mechanic.

Many common automotive issues that can arise when out on the road could be prevented with a bit of maintenance before the trip. That's why we at Delta Auto Protect packaged this checklist you can use before heading out on that road trip.

Now that fall has officially arrived, it is an ideal time to focus on the essentials to keep your vehicle safe while getting to and from class. We here at Delta Auto Protect know what it takes to keep your car in shape.

We compiled what we think are five extremely important tips that should help you save money on those costly auto repairs.

We have our fair share of experience with automotive repairs at Delta Auto Protect and in honor of our newly updated claim and service system, we have decided to share some of our knowledge with you!

These protection plans are designed to cover your automotive components after the manufacturer's warranty period has expired, ultimately protecting owners from expensive and unexpected repair costs.

When was the last time you had to deal with a car repair? It can be devastating. That is why Delta Auto Protect has put together some helpful information to help you be prepared.

Aerial counts, in-person interviews, and mail-in questionnaires were used to survey sport fish use during the coho salmon (Oncorhynchus kisutch Walbaum) season on the Copper River Delta, Alaska from 2002 through 2006. Angler counts provided an index of use on individual streams and were used to develop a spatial database exhibiting patterns of use. In-person interviews and mail-in questionnaires were used to determine the effort, catch, and harvest of coho salmon by both local residents of Cordova and nonresident anglers.

A graph $G=(V,E)$ is $delta$-hyperbolic if for any four vertices $u,v,w,x$, the two larger of the three distance sums $d(u,v)+d(w,x)$, $d(u,w)+d(v,x)$, and $d(u,x)+d(v,w)$ differ by at most $2delta geq 0$. Recent work shows that many real-world graphs have small hyperbolicity $delta$. This paper describes the eccentricity terrain of a $delta$-hyperbolic graph. The eccentricity function $e_G(v)=max{d(v,u) : u in V}$ partitions the vertex set of $G$ into eccentricity layers $C_{k}(G) = {v in V : e(v)=rad(G)+k}$, $k in mathbb{N}$, where $rad(G)=min{e_G(v): vin V}$ is the radius of $G$. The paper studies the eccentricity layers of vertices along shortest paths, identifying such terrain features as hills, plains, valleys, terraces, and plateaus. It introduces the notion of $eta$-pseudoconvexity, which implies Gromov's $epsilon$-quasiconvexity, and illustrates the abundance of pseudoconvex sets in $delta$-hyperbolic graphs. In particular, it shows that all sets $C_{leq k}(G)={vin V : e_G(v) leq rad(G) + k}$, $kin mathbb{N}$, are $(2delta-1)$-pseudoconvex. Additionally, several bounds on the eccentricity of a vertex are obtained which yield a few approaches to efficiently approximating all eccentricities. An $O(delta |E|)$ time eccentricity approximation $hat{e}(v)$, for all $vin V$, is presented that uses distances to two mutually distant vertices and satisfies $e_G(v)-2delta leq hat{e}(v) leq {e_G}(v)$. It also shows existence of two eccentricity approximating spanning trees $T$, one constructible in $O(delta |E|)$ time and the other in $O(|E|)$ time, which satisfy ${e}_G(v) leq e_T(v) leq {e}_G(v)+4delta+1$ and ${e}_G(v) leq e_T(v) leq {e}_G(v)+6delta$, respectively. Thus, the eccentricity terrain of a tree gives a good approximation (up-to an additive error $O(delta))$ of the eccentricity terrain of a $delta$-hyperbolic graph.

Embodiments of the present method and system permit an effective method for determining the optimum selection of pulse width modulation polarity and type including determining machine parameters, inputting the machine parameters into a predicted duty cycle module, determining the optimum polarity of the pulse width modulation for a predicted duty cycle based on a pulse width modulation generation algorithm, and determining the optimum type of the pulse width modulation for a predicted duty cycle based on the pulse width modulation generation algorithm.

A modulator generates a baseband digital signal from an information-bearing digital signal. The baseband signal has time-varying phase and amplitude defined by a sequence of complex data words, each having an in-phase (I) component and a quadrature (Q) component. A noise-shaping modulator generates a noise-shaped digital signal from the baseband digital signal such that quantization noise in the noise-shaping modulator is attenuated by a spectral null of its noise transfer function. The spectral null is selected by a noise-shaping parameter corresponding to a selected one of a plurality of output frequencies. A signal converter generates an analog signal conveying the information of the information-bearing digital signal on an analog carrier signal having the selected output frequency.

A modified delta linkage robot uses a reverse orientation arm linkage that includes an inwardly direct lower arm. This reverse arm orientation provides a number of advantages with respect to access over an extending surface such as may occur in a home, office or other environments shared with people. The delta linkage may also have application in certain factory environments, particularly when combined with an omni wheeled base. The linkage and the preferred linkage and omni wheeled base provide a stable movable platform. In addition this combination can advantageously include a number of sensors to take active steps to discourage and/or reduce the effect of sudden forces applied thereto.

Methods and apparatus for processing of GNSS signals are presented. These include GNSS processing with predicted precise clocks, GNSS processing with mixed-quality data, GNSS processing with time-sequence maintenance, GNSS processing with reduction of position jumps in low-latency solutions, GNSS processing with position blending to bridge reference station changes, and GNSS processing with delta-phase correction for incorrect starting position.

Typically, complex systems require a separate and expensive equalizer at the output of an analog-to-digital converter (ADC). Rather than providing a separate equalizer, the effective Signal Transfer Function (STF) of a Multi-stAge noise SHaping (MASH) ADC can be modified by leveraging available digital filtering hardware necessary for quantization noise cancellation. The modification can involves adding calculations in the software previously provided for computing digital quantization noise cancellation filter coefficients, where the calculations are added to take into account equalization as well. As a result, the signal transfer function can be modified to meet ADC or system-level signal-chain specifications without additional equalization hardware. The method is especially attractive for high-speed applications where magnitude and phase responses are more challenging to meet.

ATLANTA — Delta Air Lines says it is the first U.S. carrier to get federal clearance to carry cargo in its overhead bins, as it repurposes passenger planes amid a steep decline in travel due to the coronavirus pandemic. Atlanta-based Delta said it has received Federal Aviation Administration approval to use the overhead bin space […]

At the heart of their music is funk: deep and fluid, soulful and raunchy and thoroughly butt-wigglingly funky

Caiway en DELTA, twee regionale internet, telefonie en tv-providers, werken sinds 2018 al intensief samen. Vanaf nu kunt u via Breedbandwinkel ook buiten Zeeland voor een DELTA glasvezel abonnement kiezen. Voorwaarde is wel dat het adres van het abonnement binnen het verzorgingsgebied van Caiway ligt.

Tot nu toe konden klanten met een internetabonnement van DELTA genieten van een maximale uploadsnelheid van 45 Mb. De provider heeft echter besloten de maximale uploadsnelheden flink te verhogen. Particuliere klanten kunnen nu maximaal met 100 Mb uploaden en klanten met een businesspack met maximaal 125 Mb.

The divorce between the Delta-Montrose Electric Association and its wholesale power provide, Tri-State Generation and Transmission Association, is nearly final. All that's left is getting the OK from federal regulators. And a $62.5 million exit fee.

An attractive rewards credit card for frequent Delta flyers. While some American Express rewards cards offer great perks, like complimentary access to its exclusive network of airport lounges, you won’t get that perk with the (lounge access costs $39 per visit). However, you will get attractive rewards rates on several types of travel-related purchases along with other valuable travel benefits. This card offers you the highest reward rate when you make purchases with Delta or spend on hotel bookings, which […]

The post Delta SkyMiles® Platinum American Express Card Review appeared first on The Simple Dollar.

A top-shelf rewards credit card with luxury travel perks. The gives you access to coveted airport lounges, which is a unique benefit that will be highly attractive to some. Only a few American Express rewards cards will get you into the 10 Centurion Lounges around the world. Additionally, the card offers a number of other travel benefits, including access to Delta Sky Clubs and a free checked bag on Delta flights. Like any credit card, it does come with some […]

The post Delta SkyMiles® Reserve American Express Card Review appeared first on The Simple Dollar.

We left HCM at 8.30 by taxi and arrived in Mekong Delta around midday. We met our guide Nam and boarded a long wooden boat to take us down the river making several stops along the way.The first stop was a brick factory where Nam told me about how bri

Delta said it is making the move to protect employees amid the coronavirus pandemic, but planes have been flying near empty

We are now quite familiar with customer-written hotel reviews; we also know about the trendy use of video reviews of hotels but what about reviews of flights?! Yesterday I stumbled upon an incredible amateur video that made it to the top #20 of the most watched video of Youtube. The statistics speak for themselves: Views: 76,062 Comments: 468 Favorited: [...]

Hear about travel to the Danube Delta in Romania as the Amateur Traveler talks to Christian Cummins about traveling to this UNESCO biosphere in Europe.

I was excited to finally get the word that an article I wrote sharing my love for my hometown – San Jose, California – is out in Delta Sky Magazine this month! Time Out: San José (Are you flying Delta this month? If so, pick up a copy for me! I’d love to see it […]

The article EIT Elsewhere | “Time Out: San José” in Delta Sky Magazine originated at EverInTransit.com

Protein phosphatase 2A (PP2A) is a large enzyme family responsible for most cellular Ser/Thr dephosphorylation events. PP2A substrate specificity, localization, and regulation by second messengers rely on more than a dozen regulatory subunits (including B/R2, B'/R5, and B″/R3), which form the PP2A heterotrimeric holoenzyme by associating with a dimer comprising scaffolding (A) and catalytic (C) subunits. Because of partial redundancy and high endogenous expression of PP2A holoenzymes, traditional approaches of overexpressing, knocking down, or knocking out PP2A regulatory subunits have yielded only limited insights into their biological roles and substrates. To this end, here we sought to reduce the complexity of cellular PP2A holoenzymes. We used tetracycline-inducible expression of pairs of scaffolding and regulatory subunits with complementary charge-reversal substitutions in their interaction interfaces. For each of the three regulatory subunit families, we engineered A/B charge–swap variants that could bind to one another, but not to endogenous A and B subunits. Because endogenous Aα was targeted by a co-induced shRNA, endogenous B subunits were rapidly degraded, resulting in expression of predominantly a single PP2A heterotrimer composed of the A/B charge–swap pair and the endogenous catalytic subunit. Using B'δ/PPP2R5D, we show that PP2A complexity reduction, but not PP2A overexpression, reveals a role of this holoenzyme in suppression of extracellular signal–regulated kinase signaling and protein kinase A substrate dephosphorylation. When combined with global phosphoproteomics, the PP2A/B'δ reduction approach identified consensus dephosphorylation motifs in its substrates and suggested that residues surrounding the phosphorylation site play roles in PP2A substrate specificity.

Protein phosphatase 2A (PP2A) is a large enzyme family responsible for most cellular Ser/Thr dephosphorylation events. PP2A substrate specificity, localization, and regulation by second messengers rely on more than a dozen regulatory subunits (including B/R2, B'/R5, and B″/R3), which form the PP2A heterotrimeric holoenzyme by associating with a dimer comprising scaffolding (A) and catalytic (C) subunits. Because of partial redundancy and high endogenous expression of PP2A holoenzymes, traditional approaches of overexpressing, knocking down, or knocking out PP2A regulatory subunits have yielded only limited insights into their biological roles and substrates. To this end, here we sought to reduce the complexity of cellular PP2A holoenzymes. We used tetracycline-inducible expression of pairs of scaffolding and regulatory subunits with complementary charge-reversal substitutions in their interaction interfaces. For each of the three regulatory subunit families, we engineered A/B charge–swap variants that could bind to one another, but not to endogenous A and B subunits. Because endogenous Aα was targeted by a co-induced shRNA, endogenous B subunits were rapidly degraded, resulting in expression of predominantly a single PP2A heterotrimer composed of the A/B charge–swap pair and the endogenous catalytic subunit. Using B'δ/PPP2R5D, we show that PP2A complexity reduction, but not PP2A overexpression, reveals a role of this holoenzyme in suppression of extracellular signal–regulated kinase signaling and protein kinase A substrate dephosphorylation. When combined with global phosphoproteomics, the PP2A/B'δ reduction approach identified consensus dephosphorylation motifs in its substrates and suggested that residues surrounding the phosphorylation site play roles in PP2A substrate specificity.

Protein phosphatase 2A (PP2A) is a large enzyme family responsible for most cellular Ser/Thr dephosphorylation events. PP2A substrate specificity, localization, and regulation by second messengers rely on more than a dozen regulatory subunits (including B/R2, B'/R5, and B″/R3), which form the PP2A heterotrimeric holoenzyme by associating with a dimer comprising scaffolding (A) and catalytic (C) subunits. Because of partial redundancy and high endogenous expression of PP2A holoenzymes, traditional approaches of overexpressing, knocking down, or knocking out PP2A regulatory subunits have yielded only limited insights into their biological roles and substrates. To this end, here we sought to reduce the complexity of cellular PP2A holoenzymes. We used tetracycline-inducible expression of pairs of scaffolding and regulatory subunits with complementary charge-reversal substitutions in their interaction interfaces. For each of the three regulatory subunit families, we engineered A/B charge–swap variants that could bind to one another, but not to endogenous A and B subunits. Because endogenous Aα was targeted by a co-induced shRNA, endogenous B subunits were rapidly degraded, resulting in expression of predominantly a single PP2A heterotrimer composed of the A/B charge–swap pair and the endogenous catalytic subunit. Using B'δ/PPP2R5D, we show that PP2A complexity reduction, but not PP2A overexpression, reveals a role of this holoenzyme in suppression of extracellular signal–regulated kinase signaling and protein kinase A substrate dephosphorylation. When combined with global phosphoproteomics, the PP2A/B'δ reduction approach identified consensus dephosphorylation motifs in its substrates and suggested that residues surrounding the phosphorylation site play roles in PP2A substrate specificity.

The value of interim ¹⁸F-fluorodeoxyglucose positron emission tomography (iPET) guided treatment decisions in patients with diffuse large B-cell lymphoma (DLBCL) has been the subject of much debate. This investigation focuses on a comparison of the Deauville score and the deltaSUV_max (SUV_max) approach – two methods to assess early metabolic response to standard chemotherapy in DLBCL. Methods: Of 609 DLBCL patients participating in the Positron Emission Tomography-guided Therapy of Aggressive non-Hodgkin Lymphomas (PETAL) trial, iPET scans of 596 patients originally evaluated using the SUV_max method were available for post-hoc assessment of the Deauville score. A commonly used definition of an unfavorable iPET result according to the Deauville score is an uptake greater than that of the liver, whereas an unfavorable iPET scan with regard to the SUV_max approach is characterized as a relative reduction of the maximum standardized uptake value between baseline and iPET staging of less than or equal to 66%. We investigated the two methods’ correlation and concordance by Spearman’s rank correlation coefficient and the agreement in classification, respectively. We further used Kaplan-Meier curves and Cox regression to assess differences in survival between patient subgroups defined by the pre-specified cut-offs. Time-dependent receiver operating curve analysis provided information on the methods’ respective discrimination performance. Results: Deauville score and SUV_max approach differed in their iPET-based prognosis. The SUV_max approach outperformed the Deauville score in terms of discrimination performance – most likely due to a high number of false-positive decisions by the Deauville score. Cut-off-independent discrimination performance remained low for both methods, but cut-off-related analyses showed promising results. Both favored the SUV_max approach, e.g. for the segregation by iPET response, where the event-free survival hazard ratio was 3.14 (95% confidence interval (CI): 2.22 – 4.46) for SUV_max and 1.70 (95% CI: 1.29 – 2.24) for the Deauville score. Conclusion: When considering treatment intensification, the currently used Deauville score cut-off of an uptake above that of the liver seems to be inappropriate and associated with potential harm for DLBCL patients. The SUV_max criterion of a relative reduction of the maximum standardized uptake value of less than or equal to 66% should be considered as an alternative.

Diabetic retinopathy is the most common microvascular complication of diabetes, and in the advanced diabetic retinopathy appear vitreal fibrovascular membranes that consist of a variety of cells, including vascular endothelial cells (ECs). New therapeutic approaches for this diabetic complication are urgently needed. Here, we report that in cultured human retinal microvascular ECs, high glucose induced expression of p110, which was also expressed in ECs of fibrovascular membranes from patients with diabetes. This catalytic subunit of a receptor-regulated PI3K isoform is known to be highly enriched in leukocytes. Using genetic and pharmacological approaches, we show that p110 activity in cultured ECs controls Akt activation, cell proliferation, migration, and tube formation induced by vascular endothelial growth factor, basic fibroblast growth factor, and epidermal growth factor. Using a mouse model of oxygen-induced retinopathy, p110 inactivation was found to attenuate pathological retinal angiogenesis. p110 inhibitors have been approved for use in human B-cell malignancies. Our data suggest that antagonizing p110 constitutes a previously unappreciated therapeutic opportunity for diabetic retinopathy.

The ADA is calling on third-party payers to support dental practices in the midst of the COVID-19 pandemic.

Two additional Delta Dental member companies announced details April 27-28 of programs that will provide economic assistance and post-COVID-19 pandemic relief for members of its independent provider networks across 16 states and the District of Columbia.