A court has heard the most senior Australian Anglican clergyman to be charged with child sexual abuse used his power and influence to dissuade his alleged victim from disclosing the abuse.

Former Anglican Dean of Newcastle Graeme Lawrence "avoided" answering questions when giving his evidence about allegations he sexually assaulted a teenager at his home in the early 1990s, a court has heard.

The defence for former Anglican dean Graeme Lawrence has told a court the case against him has not been proven beyond a reasonable doubt.

Former Dean of Newcastle Graeme Lawrence is convicted over the aggravated sexual assault of a 15-year-old boy, after a judge found his evidence was not credible.

The former Anglican Dean of Newcastle Graeme Lawrence is sentenced to a maximum of eight years over the rape of a 15-year-old boy in 1991.

Energy Australia finds a unit controller at the Yallourn power station, Graeme Edwards, 54, was doing nothing wrong when he was fatally injured performing a routine task in November last year.

All three men charged over a bashing that killed Canberra man Bobby Allan, who died after collapsing at a neighbour's door seeking help for his injuries, plead guilty to manslaughter.

Legendary Australian boxer Troy Waters, a former junior middleweight world title boxing contender, dies at the age of 53 following a long battle with leukaemia.

Como crise atingiu primeiro americanos, na opinião de analistas e operadores de empresas de remessas migrantes devem se recuperar financeiramente a tempo de socorrer familiares em suas cidades originais.

In the US the licence, or marketing authorisation, for alteplase is limited to 0-3 hours after onset of stroke, but some other countries - including the UK and Australia - have extended the licence to 4.5 hours. In an analysis article on thebmj.com Brian Alper, vice president of evidence based medicine research and development at Dynamed, and...

c.1935

c.1935

Carlsruhae : D.R. Marx, 1819.

London : James Epps & Co., Limited, 1894.

Tubingen : H. Laupp, Jr, 1889.

Goettingae : Litteris Ioann. Christ. Dieterich, Acad. Typogr, [1781]

THE most important lesson in life is to always travel in hope rather than expectation. That way the almost inevitable disappointment that follows isn’t quite as crushing. A cheery thought for these troubled times.

IT’S been an up and down sort of day for Imran Akhtar. And in a much too literal sense, as far as he’s concerned. First, he had to clamber on top of the roof of the Ottoman Coffee House on Glasgow’s Berkeley Street, to make sure the temporary tarpaulin was still in place and keeping out the wind, rain, hail and snow. (It’s been one of those typical Scottish afternoons, with the weather behaving like a plump maiden aunt’s two-layered chocolate box. In other words, way too many delights

Since the introduction of effective vaccines in the United States, the incidence of invasive Haemophilus influenzae type b (Hib) disease in children aged <5 years has decreased by 99%. In 2007, in response to limited vaccine supply, Hib booster doses were deferred for 18 months.

This review found no significant change in the incidence of invasive Hib disease in the United States during the booster dose deferral period, suggesting that booster dose deferral is a reasonable approach to Hib vaccine shortages in the short-term. (Read the full article)

Omadacycline is a novel aminomethylcycline with activity against Gram-positive and -negative organisms, including Haemophilus influenzae, which is one of the leading causes of community-acquired bacterial pneumonia (CABP). The evaluation of antimicrobial agents against H. influenzae using standard murine infection models is challenging due to the low pathogenicity of this species in mice. Therefore, 24-hour dose-ranging studies using a one-compartment in vitro infection model were undertaken with the goal of characterizing the magnitude of the ratio of the area under the concentration-time curve (AUC) to the MIC (AUC/MIC ratio) associated with efficacy for a panel of five clinical H. influenzae isolates. These five isolates, which had MIC values of 1 or 2 mg/L, were exposed to omadacycline total-drug epithelial lining fluid (ELF) concentration-time profiles based on those observed in healthy volunteers following intravenous omadacycline administration. Relationships between change in log₁₀ colony forming units (CFU) from baseline at 24 hours and total-drug ELF AUC/MIC ratio for each isolate and the isolates pooled together were evaluated using Hill-type models and non-linear least squares regression. As evidenced by the high coefficient of determination (r²) of 0.88 to 0.98, total-drug ELF AUC/MIC ratio described the data well for each isolate and the isolates pooled together. The median total-drug ELF AUC/MIC ratio associated with net bacterial stasis and 1- and 2-log₁₀ CFU/mL reductions from baseline at 24 hours was 6.91, 8.91, and 11.1, respectively. These data were useful to support the omadacycline dosing regimens selected for the treatment of patients with CABP, as well as susceptibility breakpoints for H. influenzae.

tinc is a Virtual Private Network (VPN) daemon that uses tunneling and encryption to create a secure private network between multiple hosts on the Internet. This tunneling allows VPN sites to share information with each other over the Internet without exposing any information.

A new report from the Australian Energy Market Operator (AEMO) forecasts 100 percent of new power in Australia will be generated from renewable energy sources through 2020.

Glaesserella (Haemophilus) parasuis is a commensal bacterium of the upper respiratory tract in pigs and also the causative agent of Glässer’s disease, which causes significant morbidity and mortality in pigs worldwide. Isolates are characterized into 15 serovars by their capsular polysaccharide, which has shown a correlation with isolate pathogenicity. To investigate the role the capsule plays in G. parasuis virulence and host interaction, a capsule mutant of the serovar 5 strain HS069 was generated (HS069cap) through allelic exchange following natural transformation. HS069cap was unable to cause signs of systemic disease during a pig challenge study and had increased sensitivity to complement killing and phagocytosis by alveolar macrophages. Compared with the parent strain, HS069cap produced more robust biofilm and adhered equivalently to 3D4/31 cells; however, it was unable to persistently colonize the nasal cavity of inoculated pigs, with all pigs clearing HS069cap by 5 days postchallenge. Our results indicate the importance of the capsular polysaccharide to G. parasuis virulence as well as nasal colonization in pigs.

Daniel P. Small, Piero Calosi, Samuel P. S. Rastrick, Lucy M. Turner, Stephen Widdicombe, and John I. Spicer

Regulation of extracellular acid–base balance, while maintaining energy metabolism, is recognised as an important aspect when defining an organism's sensitivity to environmental changes. This study investigated the haemolymph buffering capacity and energy metabolism (oxygen consumption, haemolymph [l-lactate] and [protein]) in early benthic juveniles (carapace length <40 mm) of the European lobster, Homarus gammarus, exposed to elevated temperature and P_CO2. At 13°C, H. gammarus juveniles were able to fully compensate for acid–base disturbances caused by the exposure to elevated seawater P_CO2 at levels associated with ocean acidification and carbon dioxide capture and storage (CCS) leakage scenarios, via haemolymph [HCO₃^–] regulation. However, metabolic rate remained constant and food consumption decreased under elevated P_CO2, indicating reduced energy availability. Juveniles at 17°C showed no ability to actively compensate haemolymph pH, resulting in decreased haemolymph pH particularly under CCS conditions. Early benthic juvenile lobsters at 17°C were not able to increase energy intake to offset increased energy demand and therefore appear to be unable to respond to acid–base disturbances due to increased P_CO2 at elevated temperature. Analysis of haemolymph metabolites suggests that, even under control conditions, juveniles were energetically limited. They exhibited high haemolymph [l-lactate], indicating recourse to anaerobic metabolism. Low haemolymph [protein] was linked to minimal non-bicarbonate buffering and reduced oxygen transport capacity. We discuss these results in the context of potential impacts of ongoing ocean change and CCS leakage scenarios on the development of juvenile H. gammarus and future lobster populations and stocks.

Nadia Vicenzi, Alejandro Laspiur, Paola L. Sassi, Ruben Massarelli, John Krenz, and Nora R. Ibargüengoytia

In ectotherms, temperature exerts a strong influence on the performance of physiological and ecological traits. One approach to understand the impact of rising temperatures on animals and their ability to cope with climate change is to quantify variation in thermal-sensitive traits. Here, we examined the thermal biology, the temperature dependence and the thermal plasticity of bite force (endurance and magnitude) in Diplolaemus leopardinus, an aggressive and territorial lizard, endemic to Mendoza province, Argentina. Our results indicated that this lizard behaves like a moderate thermoregulator which uses the rocks of its environment as the main heat source. Bite endurance was not influenced by head morphometry and body temperature, whereas bite force was influenced by head length and jaw length, and exhibited thermal dependence. Before thermal acclimation treatments, the maximum bite force for D. leopardinus occured at the lowest body temperature and fell sharply with increasing body temperature. After acclimation treatments, lizards acclimated at higher temperatures exhibited greater bite force. Bite force showed phenotypic plasticity, which reveals that leopard iguanas are able to maintain (and even improve) their bite force under a rising-temperature scenario.

Nine hundred Haemophilus influenzae clinical isolates from 83 U.S. and European medical centers were tested for susceptibility by reference broth microdilution methods against ceftolozane-tazobactam and comparators. Results were stratified by β-lactamase production and infection type. Overall, ceftolozane-tazobactam MIC_50/90 values were 0.12/0.25 mg/liter, and 99.0% of isolates were inhibited at the susceptible breakpoint of ≤0.5 mg/liter; the highest MIC value was only 2 mg/liter. Our results support using ceftolozane-tazobactam to treat H. influenzae infections.

America's economic crisis deepened today as new figures revealed 26 million people have now claimed unemployment benefits since the country started going into lockdown.

Manchester United midfielder Paul Pogba has hit back at one of his biggest critics in Graeme Souness, admitting he didn't even know who the Liverpool legend was.

Graeme Souness landed the latest blow in his feud with Manchester United star Paul Pogba as he declared: "Put your medals on the table!"

Paul Pogba vs Graeme Souness is the feud that keeps on giving after the two exchanged barbs again on Tuesday.

Rio Ferdinand believes that Paul Pogba should be the one talking about his future at Manchester United - not his agent Mino Raiola.

Graeme Souness paid an emotional tribute to 'big pal' and Liverpool team-mate Michael Robinson following his death at the age of 61.

Chayse Gannon and his mother, forced to leave dad and baby brother behind, have changed accommodation around Sydney more than 12 times since he was diagnosed in February.

Bristol Myers Squibb and Acceleron Pharma’s Reblozyl (luspatercept) has secured a positivr opinion from the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) for use in the treatment of transfusion-dependent anaemia in two adult patient populations.

Manchester United midfielder Paul Pogba is bemused as to why he remains a constant source of criticism despite missing most of the campaign through injury. The 27-year-old has been restricted to just eight appearances this season due to a persistent ankle injury. Former Liverpool captain and manager Graeme Souness has been one of the most outspoken critics of Pogba since he returned to United from Juventus for a then world record £89 million ($112 million) fee in 2016.

However, Pogba claimed he did not even know who Souness was. "I didn't even know who he was, really," Pogba told the official Manchester United podcast. "I heard he was a great player and stuff like that. I know the face but (not) the name. "Like I said I'm not someone that watches a lot of (punditry), I watch a lot of football but I don't stay after the game to listen to what they say about why they did this, or why they did that. I like to focus on football." Souness - who won three European Cups, and five league titles as a player at Liverpool - responded to Pogba on Tuesday morning.

"I'm happy with that. The oldest saying in football comes to mind: 'Put your medals on the table'. I've got a big table," the former Scottish international told Sky Sports. Pogba's return to Old Trafford has failed to match the expectations of his price tag despite winning the Europa League and League Cup in his first season under Jose Mourinho. A bitter fall out with Mourinho followed in the next two seasons before the Portuguese was sacked in December 2018.

And after a brief hot streak when Ole Gunnar Solskjaer took charge, Pogba's time under the Norwegian has been beset by a lack of form and fitness. However, the French World Cup winner still believes the criticism he has received, particularly in his absence this season, is unjustified. "It's good to hear good stuff instead of bad stuff but when you play football, you know yourself. It's what your manager and team-mates want, the rest is just talk," added Pogba.

"I guess they (the critics) miss me, I don't know? I'm not someone that looks always at Sky Sports News. "When you know football, you don't need someone to tell you what's happening. "One day maybe I will meet them and ask them because I really want to know, why?"

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Former South Africa captain Graeme Smith on Tuesday said his country will welcome back former Kolpak players willing to be part of the domestic structure as he sees it as a possible way to provide more depth to the national team. Kolpak registrations, which give sportsmen from countries with associate trade agreements with the European Union the same rights as EU workers, are set to be terminated at end of 2020 following the UK's exit from the EU.

Dozens of South African cricketers have signed lucrative contracts with county cricket sides over the years but this automatically disqualifies them from playing for the national team. "With Kolpak coming to an end, I guess the willingness is always to have our best players in the system. It is up to the players to come back into the system and to make decisions on their careers," Smith, who was recently appointed as Director of Cricket by his Board, said. "From our perspective, we want to encourage all our best players to play here domestically, and then give themselves the opportunity to be selected for the national side," he was quoted as saying in 'Sky Sports'.

Kyle Abbott, Wayne Parnell, Rilee Roussow and Duanne Olivier are among the more prominent names to have taken Kolpak deals over the years, while Dane Paterson, who played two Tests against England in January, is the latest to do so. "We don't ever want to exclude players from being part of our system and we understand that the landscape of the world game is very different now to what it was," Smith said. "Open minds and how we look at these things is going to be key to how we keep our best players ¿ how we keep them motivated and in our game."

Catch up on all the latest sports news and updates here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever