TRB's Airport Cooperative Research Program (ACRP) latest Impacts on Practice explores the impact ACRP Research Report 58 : Airport Industry Familiarization and Training for Part-Time Airport Policy Makers has helped airport policy leaders, stakeholders, and policy-related decision makers understand airport administrative and operational requirements in order to assist them in making more informed policy decisions. According to an Airport Authority Board Member and Chair of the Air Service Development Com...

CBS has released a new video featuring Star Trek: Picard Prop Master Jeff Lombardi who talks about working on Picard and about...

Although general aviation airports have historically been funded by federal, state, and local entities, the private sector is increasingly playing a larger role. This involvement has ranged on a continuum from service and management contracts to singular projects at airports that involve leasing mechanisms to long-term leases and the whole-scale private development of general aviation airports. In an era of declining resources and increasingly scrutinized public expenditures, private-sector involvement i...

One of the most fascinating things about planet Earth is the way that life shapes the Earth and the Earth shapes life. We only have to look back to the Great Oxygenation Event (GOE) of 2.4 billion years ago to see how lifeforms have shaped the Earth. In that event, phytoplanktons called cyanobacteria pumped the …

Continue reading "New Data Show How Phytoplankton Pumps Carbon Out of the Atmosphere at an Enormous Scale"

The post New Data Show How Phytoplankton Pumps Carbon Out of the Atmosphere at an Enormous Scale appeared first on Universe Today.

Susan Heap, the Director of Operations at Ferrovial Services says that "Transportation is meaningful across all societies, for many different reasons. I chose a career that connected me to things that matter to all of us. I stay in this industry because of the variety of people and projects that I get to work with every day. There is always a new challenge to overcome or skill-set to learn." Thank you Susan for participating in TRB's Centennial Celebration. To read the more than 60 responses to April's q...

Airports — especially in the past two decades—have generally sought to promote and increase collaboration among the members of the airport community, particularly between an airport and its airlines. One metric of this trend has been the increase in the number of U.S. airports with full-time emergency managers, from fewer than 10 in 2007 to more than 120 today. Collaboration and increased professionalism in airport emergency management have gone hand in hand. No matter whether the incident is aircraft-re...

Množství politiků po celém světě v posledních dnech trápí zásadní otázka. Jak zabránit druhé vlně koronaviru bez škrcení ekonomiky? Možnou cestu ukázalo hlavní město Litvy. Majitelé menších podniků zde museli stejně jako na jiných místech v Evropě dočasně pozastavit svou živnost. Vedení Vilniusu ve snaze zabránit jejich krachu v rámci uvolňovaní restriktivních opatření rozhodlo o umožnění bezplatného využití veřejných prostor.

Removed From Troubles – Problem Resolved (NOT open for application) Core of Soul Removed From Troubles – Removed From Network (OPEN for application) Finch; Nine Inch Nails

Will Smith, Will Ferrell, Wanda Sykes, Stephen Colbert and Colin Quinn are among the latest additions.

Myappsclub[.]net redirect removal instructions

What is myappsclub[.]net?

Myappsclub.net is the address of a fake search engine. Such illegitimate web searching tools typically cannot generate search results and record information relating to browsing activity. Fake search engines are usually promoted by PUAs (Potentially Unwanted Applications), called browser hijackers. They do so by making modifications to browsers and often monitor users' browsing habits.

Download Apps Now browser hijacker removal instructions

What is Download Apps Now?

Download Apps Now is a rogue application, categorized as a browser hijacker. It is endorsed as an easy access tool to a variety of content. For example, to popular email providers as well as weather, news and video streaming websites. This app operates by modifying browsers in order to promote hdownloadappsnow.app - a fake search engine. Most browser hijackers are able to track browsing-related data, and it is highly likely that Download Apps Now possesses such abilities as well. Since most users download/install it inadvertently, it is also deemed to be a PUA (Potentially Unwanted Application).

UC San Diego Health launches pilot project using drones to move medical samples, supplies and documents between Jacobs Medical Center, Moores Cancer Center and the Center for Advanced Laboratory Medicine, speeding delivery of services and patient care currently managed through ground transport.

You may recall in the early days of the pandemic, that pharma giant Gilead Sciences -- which has been accused of price gouging and (just last year!) charging exorbitant prices on drug breakthroughs developed with US taxpayer funds -- was able to sneak through an orphan works designation for its drug remdesevir for COVID-19 treatment. As we pointed out, everything about this was insane, given that orphan works designations, which give extra monopoly rights to the holders (beyond patent exclusivity), are meant for diseases that don't impact a large population. Gilead used a loophole: since the ceiling for infected people to qualify for orphan drug status is 200,000, Gilead got in its application bright and early, before there were 200,000 confirmed cases (we currently have over 1.3 million). After the story went, er... viral, Gilead agreed to drop the orphan status, realizing the bad publicity it was receiving.

After a brief dalliance with chloroquine, remdesivir has suddenly been back in demand as the new hotness of possible COVID-19 treatments. Still, a close reading of the research might give one pause. There have been multiple conflicting studies, and Gilead's own messaging has been a mess.

On April 23, 2020, news of the study’s failure began to circulate. It seems that the World Health Organization (WHO) had posted a draft report about the trial on their clinical trials database, which indicated that the scientists terminated the study prematurely due to high levels of adverse side effects.

The WHO withdrew the report, and the researchers published their results in The Lancet on April 29, 2020.

The number of people who experienced adverse side effects was roughly similar between those receiving remdesivir and those receiving a placebo. In 18 participants, the researchers stopped the drug treatment due to adverse reactions.

But then...

However, also on April 29, 2020, the National Institute of Allergy and Infectious Diseases (NIAID) announced that their NIH trial showed that remdesivir treatment led to faster recovery in hospital patients with COVID-19, compared with placebo treatment.

“Preliminary results indicate that patients who received remdesivir had a 31% faster time to recovery than those who received placebo,” according to the press release. “Specifically, the median time to recovery was 11 days for patients treated with remdesivir compared with 15 days for those who received placebo.”

The mortality rate in the remdesivir treatment group was 8%, compared with 11.6% in the placebo group, indicating that the drug could improve a person’s chances of survival. These data were close to achieving statistical significance.

And then...

“In addition, there is another Chinese trial, also stopped because the numbers of new patients with COVID-19 had fallen in China so they were unable to recruit, which has not yet published its data,” Prof. Evans continues. “There are other trials where remdesivir is compared with non-remdesivir treatments currently [being] done and results from some of these should appear soon.”

Gilead also put out its own press release about another clinical trial, which seems more focused on determining the optimal length of remdesivir treatment. Suffice it to say, there's still a lot of conflicting data and no clear information on whether or not remdesevir actually helps.

Still, that hasn't stopped people from trying to figure out just how much Gilead will price gouge going forward:

The Institute for Clinical and Economic Review (ICER), which assesses effectiveness of drugs to determine appropriate prices, suggested a maximum price of $4,500 per 10-day treatment course based on the preliminary evidence of how much patients benefited in a clinical trial. Consumer advocacy group Public Citizen on Monday said remdesivir should be priced at $1 per day of treatment, since “that is more than the cost of manufacturing at scale with a reasonable profit to Gilead.”

Some Wall Street investors expect Gilead to come in at $4,000 per patient or higher to make a profit above remdesivir’s development cost, which Gilead estimates at about $1 billion.

So... we've got a range of $10 to $4,500 on a treatment that we don't yet know works, and which may or may not save lives. But, given that we're in the midst of a giant debate concerning things like "reopening the economy" -- something that can really only be done if the public is not afraid of dying (or at least becoming deathly ill) -- the value to the overall economy seems much greater than whatever amount Gilead wants to charge. It seems the right thing to do -- again, if it's shown that remdesevir actually helps -- is to just hand over a bunch of money to Gilead, say "thank you very much" and get the drug distributed as widely as possible. Though, again, it should be noted that a decent chunk of the research around remdesevir was not done or paid for by Gilead, but (yet again) via public funds to public universities, which did the necessary research. The idea that it's Gilead that should get to reap massive rewards for that seems sketchy at best. But the absolute worst outcome is one in which Gilead sticks to its standard operating procedure and prices the drug in a way that millions of Americans can't afford it, and it leads to a prolonging/expanding of the pandemic.

ML eggheads, devs get more bang for their buck, say OpenAI duo

Machine-learning algorithms are improving in performance at a rate faster than that of the underlying computer chips, we're told.…

John Cena!* Online resources only for free and end users due to the 'unprecedented period'

Video conferencing darling of the hour, Zoom, has tightened up support rules in order to "better serve" users.…

Update used wrong data type, causing Tinder to Spotify to fall over

A change in the Facebook SDK backend managed to crash many popular iOS apps that integrated the code library, used for implementing various Facebook services.…

Problems aside, no one is sure how useful phone-based tracking will be

The NHSX, a technology group within the UK government's National Health Service, has released the source code for its Android and iOS COVID-19 coronavirus contact-tracing apps in an effort to allay privacy concerns and improve the code.…

A review by Medio DeCritici (165). What I Can Remember - 90s Arcade & The Simpsons (Arcade, 1991)

Это детские смарт-часы с защитой от воды, яркими силиконовыми ремешками, камерой и кучей полезных функций.

Thank God it's Thursday because I am already burnt out from the first three days of this week. It has been an inordinately stressful week for multiple reasons, one of which I will talk about today.It's not the lab. Lab work is like heaven for me. I love escaping to the bench, avoiding human contact, and focusing on how to get something puzzling to work.It's not the next looming product launch, ; (read more)

Source: Suzy - Discipline: BioTech

This week I will answer questions sent to me by a LabSpaces reader. I welcome additional input from readers who have their own experiences with industry job hunting and using recruiters. Please do feel free to share your knowledge. Questions: I have really been enjoying your posts on your experience with working in industry. I am coming to decide that I want to jump off the academia boat and try; (read more)

Source: Suzy - Discipline: BioTech

I've previously argued that going to Mars and trying to live there is a dumb idea for the foreseeable future. Notwithstanding assorted recent comments by Elon Musk this is still true. The best treatment of Musk's proposal for a big trip to Mars comes from The Martian science fiction author Andy Weir in his comments to Ars Technica. I think Weir went too easy the obviously ridiculous low cost estimates made by Musk and didn't address many of the problems with a Mars colony. But he makes excellent points. Read the article if you are interested. I like Weir's point that solar panels weigh too much to cart all the way to Mars. Better to take a nuclear reactor. I've...

For large electric power storage projects the cost of batteries has plummeted. 2008, when battery prices were 10 times higher than they are today. This advance is timely as photovoltaic electric power prices have dropped so far that in SoCal PV is causing a growing drop in mid-day demand and therefore a much bigger spike in evening demand. Therefore there's a growing need for a cheaper way to store power generated in mid day and deliver it in the evening. You can see how much solar power output surges each day in California by clicking on some of the Daily Renewables Watch links at the Cal ISO site (the organization that manages California's electric grid). The growing supply of wind...

Alterations in calcium signaling in pancreatic acinar cells can result in pancreatitis. Although pressure changes in the pancreas can elevate cytosolic calcium (Ca2+) levels, it is not known how transient pressure-activated elevations in calcium can cause prolonged calcium changes and consequent pancreatitis. In this issue of the JCI, Swain et al. describe roles for the mechanically activated plasma membrane calcium channels Piezo1 and transient receptor potential vanilloid subfamily 4 (TRPV4) in acinar cells. The authors used genetic deletion models and cell culture systems to investigate calcium signaling. Notably, activation of the Piezo1-dependent TRPV4 pathway was independent of the cholecystokinin (CCK) stimulation pathway. These results elegantly resolve an apparent discrepancy in calcium signaling and the pathogenesis of pancreatitis in pancreatic acinar cells.

Microsoft plans to add trackpad and mouse support to its Word, Excel, and PowerPoint apps for iPad by the fall, according to TechCrunch and The Verge.

iPadOS 13.4 introduced trackpad and mouse support on all iPad models released in the past four to five years. Keyboards with trackpads include Apple's Magic Keyboard and Brydge's Pro+ for the iPad Pro and Logitech's Combo for the 10.2-inch iPad and the 10.5-inch iPad Air.

When using a trackpad, the cursor displays as a circle on the screen, popping up only when you have a finger on the trackpad. The circle then morphs into various other shapes when hovering over app icons, text fields, or other on-screen elements.

This article, "Microsoft to Add Trackpad Support to Word, Excel, and PowerPoint Apps on iPad" first appeared on MacRumors.com

Discuss this article in our forums

Apple in mid-April reopened Apple Garosugil, its lone store in South Korea, located in the Seoul's Gangnam District.


Apple's South Korea reopening has served as a test ground for further store reopenings, and Apple created an instructional video on reopening practices that's now being shared with other retail employees around the world as they prepare to reopen stores. We're not able to share the video, but it provides a good overview of the measures Apple is putting in place to safely operate retail locations.

Retail employees are following a strict set of guidelines that very heavily emphasize social distancing of two meters (or six feet in the United States). Apple is taking the following measures:

• Prior to when work starts, all employees undergo a health screening complete with a temperature check, with the results logged in a daily spreadsheet.


• Daily briefings are done in the mornings in the Forum area at Apple Stores, with employees making sure to sit at least two meters apart.


• Prior to being allowed in the store, customers are also given a temperature check.


• All ‌Apple Stores‌ are providing hand sanitizer, which customers are encouraged to use.


• Stores are limiting the number of people inside, forming lines with customers waiting at least two meters apart.


• Products purchased by customers or returned after repair are delivered from the back in a relay system, being handed off from employee to employee to allow each person to stay in a separated zone without back and forth.


• Product specialists and Genius Bar staff are positioning themselves across tables away from customers in order to maintain distance.


• In the forum area, employees sit one cube away from customers they're interacting with.


• Employees are encouraged to communicate with one another through the Talk app to cut down on unnecessary movement within the store.


• Half of the workstations in the back are empty, with employees working at alternating workstations to keep more distance between them.


• Tables have been rearranged to put products on corners to prevent customers from being near one another.


• Products on tables have been reduced.


• Communal tables and couches have been removed from employee break rooms and have been replaced with individual chairs evenly spaced about the room.


• Operating hours are reduced.


• Employees are all wearing face masks.

After opening its South Korea store on April 16, Apple has reopened its sole store in Vienna, Austria, and 21 stores located in Australia. Stores in Germany will begin reopening on May 11, and all of the newly opened locations are following many of the same guidelines listed above to keep both customers and employees safe.

There's no word yet on when Apple retail stores in the United States will start to reopen, but Apple CEO Tim Cook last week said that stores in North America will begin reopening starting in the month of May.

Apple plans to evaluate data and make reopening decisions on a city by city, county by county basis, following local guidelines and recommendations before opening up a store.
This article, "Apple Preparing Retail Employees to Return to Work With Tips From South Korea Reopening" first appeared on MacRumors.com

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— seeya soon, boring details about today’s comic: made with:

THE AMERICAN PEOPLE IN THIS PARTICULAR MOMENT IN OUR HISTORY MUST MAKE A VERY FUNDAMENTAL DECISION, AND THAT DECISION IS DO WE CONTINUE THE STATUS QUO WHICH INCLUDES A 40-YEAR DECLINE OF OUR MIDDLE CLASS AND A HUGE AND GROWING GAP BETWEEN THE VERY, VERY RICH AND EVERYONE ELSE, OR DO WE FIGHT FOR A BOLD AND MEANINGFUL ECONOMIC AGENDA THAT CREATES JOBS, RAISES WAGES, PROTECTS OUR ENVIRONMENT AND PROVIDES HEALTH CARE FOR EVERY AMERICAN Continue reading →

"Trump didn’t hijack the populism, the Democratic Party made a gift of it to him. And he simply accepted it. … that elite … made a decision that in the midst of a global insurrection against political corruption and economic oligarchy that Hillary Clinton’s 'pay to play' politics in global finance capitalism would somehow play better than Bernie Sanders Democratic Socialism. … they ignored every poll they had, all the data they had, and even all the anecdotes they could possibly have accumulated in order to reach the conclusion that Hillary was a stronger candidate than Bernie. … And I remain certain that if anyone other than Clinton - and certainly if you accept for just one moment that when all the polls said the right things by such wide margins for so long they might be right - Bernie Sanders could have won this had he been the nominee, like Roosevelt took out Landon." Continue reading →

NCIS and NCIS: New Orleans will air the first new episodes of 2017 tonight. You can find sneak peeks, tweets and photos...

NCIS: Los Angeles will air the first new episode of 2017 tonight. “Kulinda” is scheduled to start at 8:00pm ET/PT. (If anything...