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Characterization of the Fe metalloproteome of a ubiquitous marine heterotroph, Pseudoalteromonas (BB2-AT2): multiple bacterioferritin copies enable significant Fe storage

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00034E, Paper
Open Access
Michael G. Mazzotta, Matthew R. McIlvin, Mak A. Saito
Despite the extreme scarcity of Fe in seawater, the marine heterotroph Pseudoalteromonas has expansive Fe storage capacity and utilization strategies.
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Proteomic analysis of the S. cerevisiae response to the anticancer ruthenium complex KP1019

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00008F, Paper
Open Access
Laura K. Stultz, Alexandra Hunsucker, Sydney Middleton, Evan Grovenstein, Jacob O’Leary, Eliot Blatt, Mary Miller, James Mobley, Pamela K. Hanson
Proteomic analysis reveals that the anticancer ruthenium KP1019 induces proteotoxic, genotoxic, and oxidative stress responses in Saccharomyces cerevisiae.
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The first copper(II) complex with 1,10-phenanthroline and salubrinal with interesting biochemical properties

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00006J, Paper
Sebastiano Masuri, Enzo Cadoni, Maria Grazia Cabiddu, Francesco Isaia, Maria Giovanna Demuru, Lukáš Moráň, David Buček, Petr Vaňhara, Josef Havel, Tiziana Pivetta
The novel complex Cu(phen)2(salubrinal)(ClO4)2 shows high free radical scavenging activity and good cytotoxic activity and induces cell death through ER-stress.
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Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00064G, Paper
Diana Fontinha, Silvia Andreia Sousa, Tânia S. Morais, Miguel Prudêncio, Jorge Leitão, Yann Le Gal, Dominique Lorcy, Rafaela Silva, Mariana Velho, Dulce Belo, Manuel Almeida, Joana Guerreiro, Teresa Pinheiro, Fernanda M. Marques
The anticancer, antimicrobial and antiplasmodial activities of six gold(III) bis(dithiolene) complexes were studied. Complexes (1-6) showed relevant anticancer properties against A2780/A2780cisR ovarian cancer cells (IC50 values of 0.08-2 µM), also...
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Studies of the labile lead pool using a rhodamine-based fluorescent probe

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00056F, Communication
Jianping Zhu, Jia Hao Yeo, Amy A. Bowyer, Nicholas Proschogo, Elizabeth J. New
A rhodamine-based fluorescent lead probe reports on the labile lead pool within cells.
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Enantiomeric Copper Based Anticancer Agents Promoting Sequence-Selective Cleavage of G-Quadruplex Telomeric DNA and non-random cleavage of plasmid DNA

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00084A, Paper
Sabiha Parveen, J. A. Cowan, Zhen Yu, Farukh Arjmand
Copper-based binuclear enantiomeric complexes 1S and 1R were synthesized as anticancer chemotherapeutic agents to target G-quadruplex rich region of DNA and thoroughly characterized by various spectroscopic and single X-ray crystal...
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Gene expression in mouse muscle over time after nickel pellet implantation

Metallomics, 2020, 12,528-538
DOI: 10.1039/C9MT00289H, Paper
Desmond I. Bannon, Wenjun Bao, Stephen D. Turner, Wilfred C. McCain, William Dennis, Russ Wolfinger, Ed Perkins, Roger Abounader
Implanted nickel becomes toxic when it exceeds homeostasis, initiating a range of global gene effects over time, including oxidative phosphorylation and immune responses, which are impacted in opposite directions.
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Comparative differential cuproproteomes of Rhodobacter capsulatus reveal novel copper homeostasis related proteins

Metallomics, 2020, 12,572-591
DOI: 10.1039/C9MT00314B, Paper
Nur Selamoglu, Özlem Önder, Yavuz Öztürk, Bahia Khalfaoui-Hassani, Crysten E. Blaby-Haas, Benjamin A. Garcia, Hans-Georg Koch, Fevzi Daldal
Cuproproteome of model bacterium Rhodobacter capsulatus reveals 75 Cu-responsive proteins that are strongly influenced (2–300 fold) by Cu availability.
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Peptide bond cleavage in the presence of Ni-containing particles

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00070A, Communication
Nina Ewa Wezynfeld, Tomasz Frączyk, Arkadiusz Bonna, Wojciech Bal
NiO nanoparticles and non-stoichiometric black NiO were shown to be effective sources of Ni2+ ions causing sequence-selective peptide bond hydrolysis. NiO nanoparticles were as effective in this reaction as their...
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Investigation of the impact of magnesium versus titanium implants on protein composition in osteoblast by label free quantification

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00028K, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
M. Omidi, N. Ahmad Agha, A. Müller, F. Feyerabend, H. Helmholz, R. Willumeit-Römer, H. Schlüter, B. J. C. Luthringer-Feyerabend
To our knowledge, this is the first report describing and comparing the effects of magnesium and titanium biomaterials on human osteoblast proteome.
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Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00074D, Paper
Fabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. Soares
Huntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...
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A liver-targeting Cu(I) chelator relocates Cu in hepatocytes and promotes Cu excretion in a murine model of Wilson’s disease

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00069H, Paper
Marie Monestier, AnaÏS M. Pujol, Aline Lamboux, Martine Cuillel, Isabelle Pignot-Paintrand, Doris Cassio, Peggy Charbonnier, Khémary Um, Amélie Harel, Sylvain BOHIC, Christelle GATEAU, Vincent Balter, Virginie Brun, Pascale Delangle, Elisabeth Mintz
Copper chelation is the most commonly used therapeutic strategy nowadays to treat Wilson’s disease, a genetic disorder primarily inducing a pathological accumulation of Cu in the liver. The mechanism of...
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Linc-ROR promotes arsenite-transformed keratinocyte proliferation by inhibiting P53 activity

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00076K, Paper
Xinyang Li, Chao Zuo, Mei Wu, Zunzhen Zhang
Linc-ROR modulates the cell proliferation in arsenite-transformed keratinocytes via inhibiting P53 activity through the PI3K/AKT pathway.
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In vitro selenium supplementation suppresses key mediators involved in myometrial activation and rupture of fetal membranes

Metallomics, 2020, Advance Article
DOI: 10.1039/D0MT00063A, Paper
Dineli Matheesha Kalansuriya, Ratana Lim, Martha Lappas
Selenium suppresses key mediators involved in preterm birth in human fetal membranes and myometrium.
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TSE proprietor extends helping hand to widows, differently abled persons

TSE proprietor extends helping hand to widows, differently abled persons




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CLP approaches PM, Railway Minister

CLP approaches PM, Railway Minister




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Dr S Ranjan provides relief material again

Dr S Ranjan provides relief material again




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[ASAP] Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00001




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[ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020

ACS Combinatorial Science
DOI: 10.1021/acscombsci.0c00061




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[ASAP] Experimental and Theoretical Investigation on Phase Formation and Mechanical Properties in Cr–Co–Ni Alloys Processed Using a Novel Thin-Film Quenching Technique

ACS Combinatorial Science
DOI: 10.1021/acscombsci.9b00170




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Immunotherapy drug improves outcomes for some children with relapsed leukemia

For children and young adults with certain relapsed B-cell acute lymphoblastic leukemia (B-ALL), the immunotherapy drug blinatumomab is superior to standard chemotherapy, an NCI-sponsored Children’s Oncology Group trial shows.




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Testing with combined biopsy method improves prostate cancer diagnosis in NCI study

Testing for prostate cancer with a combined biopsy method led to more accurate diagnosis and prediction of the course of the disease in an NCI study. The method is poised to reduce the risk of prostate cancer overtreatment and undertreatment.




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In NIH trial, selumetinib shrinks tumors, provides clinical benefit for children with NF1

An NCI clinical trial finds the drug selumetinib improves outcomes for children with neurofibromatosis type 1 (NF1), shrinking inoperable tumors called plexiform neurofibromas, reducing pain, and improving function and overall quality of life.




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NCI study provides genetic insights into osteosarcoma in children

A new study offers insight into genetic alterations associated with osteosarcoma, the most common bone tumor of children and adolescents, and the findings have implications for genetic testing of children with osteosarcoma and their families.




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The colonial fantasy : why white Australia can't solve black problems / Sarah Maddison

Maddison, Sarah, author




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Report on the impact of inauthentic art and craft in the style of First Nations peoples / House of Representatives Standing Committee on Indigenous Affairs

Australia. Parliament. House of Representatives. Standing Committee on Indigenous Affairs, author, issuing body




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Manyjilyjarra - English pictorial dictionary of landscape terms / [prepared for Kanyirninpa Jukurrpa by Clair Hill and Andrew Turk with assistance from Martu language speakers: Gladys Bidu; Jakayu Biljabu; Nancy Chapman; Mulyatingki Marney; Minyawu Miller




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Zhong jie yu fa zhan de hua ti tu chu lei xing xue yan jiu = Topic prominence in typological interlanguage development of Chinese students' English / Yang Lianrui zhu

Yang, Lianrui, 1963- author




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Zhongguo di fang zheng fu ji xiao guan li yan jiu : yi Shenzhen de shi jian wei li = Research on performance management of local government in China : a case of Shenzhen practice / Zhu Yanqiang zhu

Zhu, Yanqiang




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Zhongguo Cheng Zhen zhi gong shi ye bao xian wen ti yan jiu = The research for the problem of Chinese city officers and workers unemployment insurance / Shen Shuigen zhu

Shen, Shuigen




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China under the Empress Dowager. Chinese

Bland, J. O. P. (John Otway Percy), 1863-1945




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Price of inequality : how today's divided society endangers our future. Chinese

Stiglitz, Joseph E




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[ASAP] Expanding Ligand Space: Preparation, Characterization, and Synthetic Applications of Air-Stable, Odorless Di-<italic toggle="yes">tert</italic>-alkylphosphine Surrogates

ACS Catalysis
DOI: 10.1021/acscatal.0c01414




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[ASAP] 4-Nitrophenol Reduction: Probing the Putative Mechanism of the Model Reaction

ACS Catalysis
DOI: 10.1021/acscatal.0c00725




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[ASAP] Correction to “Promoter Rather Than Inhibitor: Phosphorous Incorporation Accelerates the Activity of V<sub>2</sub>O<sub>5</sub>–WO<sub>3</sub>/TiO<sub>2</sub> Catalyst for Selective Catalytic Reductio

ACS Catalysis
DOI: 10.1021/acscatal.0c01661




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[ASAP] Removal of Hydrogen Poisoning by Electrostatically Polar MgO Support for Low-Pressure NH<sub>3</sub> Synthesis at a High Rate over the Ru Catalyst

ACS Catalysis
DOI: 10.1021/acscatal.0c00954




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[ASAP] A Mechanistic Rationale Approach Revealed the Unexpected Chemoselectivity of an Artificial Ru-Dependent Oxidase: A Dual Experimental/Theoretical Approach

ACS Catalysis
DOI: 10.1021/acscatal.9b04904




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[ASAP] Deciphering a Reaction Network for the Switchable Production of Tetrahydroquinoline or Quinoline with MOF-Supported Pd Tandem Catalysts

ACS Catalysis
DOI: 10.1021/acscatal.0c00899




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[ASAP] Methanol Synthesis from CO<sub>2</sub> Hydrogenation over a Potassium-Promoted Cu<italic toggle="yes"><sub>x</sub></italic>O/Cu(111) (<italic toggle="yes">x</italic> = 2) Model Sur

ACS Catalysis
DOI: 10.1021/acscatal.9b05226




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[ASAP] Photocatalytic CO<sub>2</sub> Reduction to C2+ Products

ACS Catalysis
DOI: 10.1021/acscatal.0c00478




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[ASAP] Comprehensive Insights into the Catalytic Mechanism of Middle East Respiratory Syndrome 3C-Like Protease and Severe Acute Respiratory Syndrome 3C-Like Protease

ACS Catalysis
DOI: 10.1021/acscatal.0c00110




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[ASAP] Photoredox Catalysis: The Reaction Mechanism Can Adjust to Electronic Properties of a Catalyst

ACS Catalysis
DOI: 10.1021/acscatal.0c00200




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[ASAP] Development of Ketone-Based Brominating Agents (KBA) for the Practical Asymmetric a-Bromination of Aldehydes Catalyzed by Tritylpyrrolidine

ACS Catalysis
DOI: 10.1021/acscatal.0c01596




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FDA approves first in-home test for coronavirus

Patients will swab their own nose using a testing kit sent by the company and will mail it in an insulated package back to the company.




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Project CARD to push local production of testing kits

Niti Aayog and the Department of Biotechnology have launched the Consortium for Affordable & Rapid Diagnostics (CARD) to scale up India’s capacity to make coronavirus testing kits. The move comes after India faced quality issues with Chinese-made antibody testing kits.




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Bharat Bio leads CSIR project to develop human antibodies

This programme brings together academia — National Centre for Cell Science, Indian Institute of Technology, Indore, and industry – PredOmix Technologies and Bharat Biotech, in a collaborative mode for a public health emergency.




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Forest Dept. steps up vigil to prevent poaching

Base camps, check-posts set up as part of the drive




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Coronavirus | U.S. unemployment rate spikes to 14.7%, highest since Great Depression

As companies have laid off tens of millions, lives have been upended across the country.




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Pakistan court orders auction of ex-Taliban chief’s property

Mullah Akhtar Mansour was killed in a drone strike in 2016




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Trump utterly failed to prepare for COVID-19: Joe Biden

The President’s entire economic strategy is focussed on helping the wealthy, alleges the Democratic Party’s presidential nominee