cro

[ASAP] Flexible Fitting of Small Molecules into Electron Microscopy Maps Using Molecular Dynamics Simulations with Neural Network Potentials

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01167




cro

[ASAP] Simulation-Based Methods for Model Building and Refinement in Cryoelectron Microscopy

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00087




cro

[ASAP] Propagation of Conformational Coordinates Across Angular Space in Mapping the Continuum of States from Cryo-EM Data by Manifold Embedding

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01115




cro

[ASAP] Cylindrical Similarity Measurement for Helices in Medium-Resolution Cryo-Electron Microscopy Density Maps

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00010




cro

[ASAP] Live Analysis and Reconstruction of Single-Particle Cryo-Electron Microscopy Data with CryoFLARE

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01102




cro

[ASAP] Mechanism-Based Rational Discovery and <italic toggle="yes">In Vitro</italic> Evaluation of Novel Microtubule Stabilizing Agents with Non-Taxol-Competitive Activity

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.9b01133




cro

[ASAP] Understanding the Contributions of Microscopic Heat Transfer to Thermal Conductivities of Liquid Aldehydes and Ketones by Molecular Dynamics Simulation

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00184




cro

[ASAP] Scope of 3D Shape-Based Approaches in Predicting the Macromolecular Targets of Structurally Complex Small Molecules Including Natural Products and Macrocyclic Ligands

Journal of Chemical Information and Modeling
DOI: 10.1021/acs.jcim.0c00161




cro

Harnessing chaos: the Bible in English political discourse since 1968 / James G. Crossley

Online Resource




cro

The cross: history, art, and controversy / Robin M. Jensen

Hayden Library - BV160.J46 2017




cro

Harnessing chaos: the Bible in English political discourse since 1968 / James G. Crossley

Online Resource




cro

Understanding host-microbiome interactions -- an omics approach: omics of host-microbiome association / Ravindra Pal Singh, Ramesh Kothari, Prakash G. Koringa, Satya Prakash Singh, editors

Online Resource




cro

The mammalian auditory pathways: synaptic organization and microcircuits / Douglas L. Oliver, Nell B. Cant, Richard R. Fay, Arthur N. Popper, editors

Online Resource




cro

Cochlear anatomy via microdissection with clinical implications: an atlas / Charles G. Wright, Peter S. Roland

Online Resource




cro

GABA and the basal ganglia: from molecules to systems / edited by James M. Tepper, Elizabeth D. Abercrombie and J. Paul Bolam

Online Resource




cro

Hippocampal microcircuits: a computational modeler's resource book / Vassilis Cutsuridis, Bruce P. Graham, Stuart Cobb, Imre Vida, editors

Online Resource




cro

Mate choice: the evolution of sexual decision making from microbes to humans / Gil G. Rosenthal

Hayden Library - QL761.R574 2017




cro

In search of the Never-Never: Mickey Dewar: champion of history across many genres / Mickey Dewar ; edited by Ann McGrath

Online Resource




cro

Modernist physics: waves, particles, and relativities in the writings of Virginia Woolf and D. H. Lawrence / Rachel Crossland

Hayden Library - PR149.S4 C76 2018




cro

Breasts across motherhood [electronic resource] : lived experiences and critical examinations / edited by Patricia Drew and Rosann Edwards.

Bradford, Ontario : Demeter Press, 2020.




cro

Leaders and Leadership in Serbian Primary Schools [electronic resource]: Perspectives Across Two Worlds

Rakovi, Jelena




cro

Micro-residential Dynamics [electronic resource] : A Case Study of Whitechapel, London / by Shlomit Flint Ashery

Flint Ashery, Shlomit, author




cro

Shojo Across Media [electronic resource]: Exploring "Girl" Practices in Contemporary Japan




cro

Gold(III) bis(dithiolene) complexes: from molecular conductors to prospective anticancer, antimicrobial and antiplasmodial agents

Metallomics, 2020, Accepted Manuscript
DOI: 10.1039/D0MT00064G, Paper
Diana Fontinha, Silvia Andreia Sousa, Tânia S. Morais, Miguel Prudêncio, Jorge Leitão, Yann Le Gal, Dominique Lorcy, Rafaela Silva, Mariana Velho, Dulce Belo, Manuel Almeida, Joana Guerreiro, Teresa Pinheiro, Fernanda M. Marques
The anticancer, antimicrobial and antiplasmodial activities of six gold(III) bis(dithiolene) complexes were studied. Complexes (1-6) showed relevant anticancer properties against A2780/A2780cisR ovarian cancer cells (IC50 values of 0.08-2 µM), also...
The content of this RSS Feed (c) The Royal Society of Chemistry




cro

Selenium deficiency exacerbates LPS-induced necroptosis by regulating miR-16-5p targeting PI3K in chicken tracheal tissue

Metallomics, 2020, 12,562-571
DOI: 10.1039/C9MT00302A, Paper
Lanqiao Wang, Xu Shi, Shufang Zheng, Shiwen Xu
Se deficiency can induce necroptosis in tracheal tissue. LPS-induced necroptosis can be exacerbated by Se deficiency. The miR-16-5p-PI3K/AKT pathway participates in the occurrence of necroptosis.
The content of this RSS Feed (c) The Royal Society of Chemistry




cro

The role of necroptosis and apoptosis through the oxidative stress pathway in the liver of selenium-deficient swine

Metallomics, 2020, 12,607-616
DOI: 10.1039/C9MT00295B, Paper
Yuan Zhang, Dahai Yu, Jiuli Zhang, Jun Bao, Chaohua Tang, Ziwei Zhang
Necroptosis is regarded as a new paradigm of cell death that plays a key role in the liver damage observed with selenium (Se) deficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry




cro

World Red Cross Day observed

World Red Cross Day observed




cro

IRCS State branch: observes World Red cross Day

IRCS State branch: observes World Red cross Day




cro

[ASAP] Lattice Strain Measurement of Core@Shell Electrocatalysts with 4D Scanning Transmission Electron Microscopy Nanobeam Electron Diffraction

ACS Catalysis
DOI: 10.1021/acscatal.0c00224




cro

[ASAP] Microenvironment of MOF Channel Coordination with Pt NPs for Selective Hydrogenation of Unsaturated Aldehydes

ACS Catalysis
DOI: 10.1021/acscatal.0c00682




cro

[ASAP] Regioselective Cross-Electrophile Coupling of Epoxides and (Hetero)aryl Iodides via Ni/Ti/Photoredox Catalysis

ACS Catalysis
DOI: 10.1021/acscatal.0c01199




cro

Mahindra group pumps Rs 500-crore in two-wheeler business

The Mahindra Group has invested about Rs 450-500 crore into their two-wheeler business to fund a turnaround plan despite some investors being sceptical of the company’s move.




cro

The home microbiome and a news roundup (29 August 2014)

Sharing microbes around the house; roundup of daily news.




cro

Antimicrobial resistance and a news roundup

Stephen Baker discusses the challenges faced by lower-income countries when fighting antimicrobial resistant infections. Emily Conover discusses daily news stories. Hosted by Susanne Bard. [Img: Merton Wilton/flickr/CC BY-NC 2.0]




cro

Child abuse across generations and a news roundup

Cathy Spatz Widom discusses whether child abuse is transmitted across generations. Angela Colmone has a round-up of advances in immunotherapy from Science Translational Medicine, and David Grimm discusses daily news stories. Hosted by Susanne Bard. [Img: Luigi Mengato/flickr/Creative Commons]




cro

Climate change and China's tea crop and a news roundup

Christina Larson discusses the impact of climate change on China's tea and other globally sensitive crops, and Emily Conover discusses daily news stories with Sarah Crespi. Hosted by Susanne Bard. [Img: Yosomono/Creative Commons License BY 2.0, via flickr]




cro

Genes and the human microbiome and a news roundup

Seth Bordenstein discusses how our genes affect the composition of our microbiome, influencing our health, and David Grimm talks with Sarah Crespi about the origins of the Basque language, the benefits of being raised in a barn, and how some flying ants lost their wings. Hosted by Susanne Bard. [Image credit: Decaseconds/CC BY-NC 2.0, via flickr




cro

How our gut microbiota change as we age and a daily news roundup

Paul O'Toole discusses what happens to our gut microbes as we age; David Grimm talks about competent grandmas, our tilted moon, and gender in the brain. Hosted by Susanne Bard. [Img: Dhinakaran Gajavarathan CC BY 2.0, via flickr]




cro

Podcast: Combatting malnutrition with gut microbes, fighting art forgers with science, and killing cancer with gold

Online News Editor David Grimm shares stories on how our abilities shape our minds, killing cancer cells with gold nanoparticles, and catching art forgery with cat hair.   Laura Blanton joins host Sarah Crespi to discuss how nourishing our gut microbes may prevent malnutrition. Read the related research in Science.   [Image: D. S. Wagner et al., Biomaterials, 31 (2010)]   Authors: Sarah Crespi; David Grimm




cro

Podcast: An omnipresent antimicrobial, a lichen ménage à trois, and tiny tide-induced tremors

Stories on a lichen threesome, tremors caused by tides, and a theoretical way to inspect nuclear warheads without looking too closely at them, with Catherine Matacic.   Despite concerns about antibiotic resistance, it seems like antimicrobials have crept into everything—from hand soap to toothpaste, and even fabrics. What does the ubiquitous presence of these compounds mean for our microbiomes? Alyson Yee talks with host Sarah Crespi about one antimicrobial in particular—triclosan—which has been partially banned in the European Union.     [Image: T. Wheeler/Music: Jeffrey Cook]




cro

What hunter-gatherer gut microbiomes have that we don’t, and breaking the emoji code

Sarah Crespi talks to Sam Smits about how our microbial passengers differ from one culture to the next—are we losing diversity and the ability to fight chronic disease? For our books segment, Jen Golbeck talks with Vyvyan Evans about his book The Emoji Code: The Linguistics Behind Smiley Faces and Scaredy Cats. Listen to previous podcasts. [Image: Woodlouse/Flickr; Music: Jeffrey Cook]




cro

Mysteriously male crocodiles, the future of negotiating AIs, and atomic bonding between the United States and China

This week we hear stories on involving more AIs in negotiations, tiny algae that might be responsible for killing some (not all) dinosaurs, and a chemical intended to make farm fish grow faster that may be also be causing one area’s crocodile population to skew male—with Online News Editor David Grimm.   Sarah Crespi talks to Rich Stone about being on the scene for a joint U.S.-China mission to remove bomb-grade fuel from a nuclear reactor in Ghana.   Listen to previous podcasts.    [Image:Chad Sparkes; Music: Jeffrey Cook]




cro

Who visits raccoon latrines, and boosting cancer therapy with gut microbes

David Grimm—online news editor for Science—talks with Sarah Crespi about a long-term project monitoring raccoon latrines in California. What influence do these wild bathrooms have on the ecosystem? Sarah also interviews Christian Jobin of the University of Florida in Gainesville about his Perspective on three papers linking the success of cancer immunotherapy with microbes in the gut—it turns out which bacteria live in a cancer patient’s intestines can predict their response to this cutting-edge cancer treatment. Read the related papers: Routy et al., Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors, Science 2018 Gopalakrishnan et al., Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients, Science 2018 Matson et al., The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients, Science 2018 aan4236 Listen to previous podcasts. [Image: cuatrok77/Flickr; Music: Jeffrey Cook]




cro

Children sue the U.S. government over climate change, and how mice inherit their gut microbes

A group of children is suing the U.S. government—claiming their rights to life, liberty, and property are under threat from climate change thanks to government policies that have encouraged the use and extraction of fossil fuels. Host Meagan Cantwell interviews news writer Julia Rosen on the ins and outs of the suit and what it could mean if the kids win the day.    Also this week, host Sarah Crespi talks with Andrew Moeller of Cornell University about his work tracing the gut microbes inherited through 10 generations of mice. It turns out the fidelity is quite high—you can still tell mice lineages apart by their gut microbes after 10 generations. And horizontally transmitted microbes, those that jump from one mouse line to another through exposure to common spaces or handlers, were more likely than inherited bacteria to be pathogenic and were often linked to illnesses in people. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Bob Dass/Flickr; Music: Jeffrey Cook] 




cro

Treating the microbiome, and a gene that induces sleep

Orla Smith, editor of Science Translational Medicine joins host Sarah Crespi to talk about what has changed in the past 10 years of microbiome research, what’s getting close to being useful in treatment, and how strong, exactly, the research is behind those probiotic yogurts. When you’re sick, sleeping is restorative—it helps your body recover from nasty infections. Meagan Cantwell speaks with Amita Sehgal, professor of neuroscience at the University of Pennsylvania and an investigator at Howard Hughes Medical Institute in Chevy Chase, Maryland, about the process of discovering a gene in fruit flies that links sleep and immune function. This week’s episode was edited by Podigy. Download the transcript (PDF) Listen to previous podcasts. About the Science Podcast [Music: Jeffrey Cook]




cro

Where our microbiome came from, and how our farming and hunting ancestors transformed the world

Micro-organisms live inside everything from the human gut to coral—but where do they come from? Host Meagan Cantwell talks to Staff Writer Elizabeth Pennisi about the first comprehensive survey of microbes in Hawaii’s Waimea Valley, which revealed that plants and animals get their unique microbiomes from organisms below them in the food chain or the wider environment. Going global, Meagan then speaks with Erle Ellis, professor of geography and environmental science at the University of Maryland, Baltimore County, about a project that aggregated the expertise of more than 250 archaeologists to map human land use over the past 10,000 years. This detailed map will help fine-tune climate models. This week’s episode was edited by Podigy. Ads on this show: Science Sessions Podcast; Kroger Download a transcript (PDF)  Listen to previous podcasts. About the Science Podcast [Image: Chris Couderc/Flickr; Music: Jeffrey Cook]




cro

Researchers flouting clinical reporting rules, and linking gut microbes to heart disease and diabetes

Though a law requiring clinical trial results reporting has been on the books for decades, many researchers have been slow to comply. Now, 2 years after the law was sharpened with higher penalties for noncompliance, investigative correspondent Charles Piller took a look at the results. He talks with host Sarah Crespi about the investigation and a surprising lack of compliance and enforcement. Also this week, Sarah talks with Brett Finlay, a microbiologist at the University Of British Columbia, Vancouver, about an Insight in this week’s issue that aims to connect the dots between noncommunicable diseases like heart disease, diabetes, and cancer and the microbes that live in our guts. Could these diseases actually spread through our microbiomes? This week’s episode was edited by Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF). [Image: stu_spivack/Flickr; Music: Jeffrey Cook]




cro

A cryo–electron microscope accessible to the masses, and tracing the genetics of schizophrenia

Structural biologists rejoiced when cryo–electron microscopy, a technique to generate highly detailed models of biomolecules, emerged. But years after its release, researchers still face long queues to access these machines. Science’s European News Editor Eric Hand walks host Meagan Cantwell through the journey of a group of researchers to create a cheaper, more accessible alternative. Also this week, host Joel Goldberg speaks with psychiatrist and researcher Goodman Sibeko, who worked with the Xhosa people of South Africa to help illuminate genetic details of schizophrenia. Though scientists have examined this subject among Western populations, much less is known about the underlying genetics of people native to Africa. This week’s episode was edited by Podigy. Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast




cro

From nose to toes—how coronavirus affects the body, and a quantum microscope that unlocks the magnetic secrets of very old rocks

Coronavirus affects far more than just the lungs, and doctors and researchers in the midst of the pandemic are trying to catalog—and understand—the virus’ impact on our bodies. Staff Writer Meredith Wadman joins host Sarah Crespi to discuss what we know about how COVID-19 kills. See all of our News coverage of the pandemic here, and all of our Research and Editorials here. Also this week, Staff Writer Paul Voosen talks with Sarah about quantum diamond microscopes. These new devices are able to detect minute traces of magnetism, giving insight into the earliest movements of Earth’s tectonic plates and even ancient paleomagnetic events in space. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF).




cro

Nanotechnology for Microfluidics


 
The book focuses on microfluidics with applications in nanotechnology. The first part summarizes the recent advances and achievements in the field of microfluidic technology, with emphasize on the the influence of nanotechnology. The second part introduces various applications of microfluidics in nanotechnology, such as drug delivery, tissue engineering and biomedical diagnosis.

Read More...