At least four Kentucky school districts were forced to close last Thursday as hundreds of teachers called in sick to continue protesting what they believe to be anti-public education proposals in the state legislature.

Convinced that the show must go on, many high school theater troupes are turning to livestreamed productions, outdoor performances, and radio plays.

State Education Secretary Rebecca Holcombe has been officiating over the state's politically thorny district consolidation process, and many are asking for it to be placed on hold until the state board replaces her.

The Winnipeg Jets will be without defenceman Logan Stanley for the short-term future.

Nov. 12—Jarrett Gronski wasn't expecting to cry the morning before playing Wayne State. Like most athletes, the Bemidji State football team's senior running back has his pregame rituals. But that routine shook out a little differently before the Beavers' game against the Wildcats. John Gronski — Jarrett's father and a prolific running back for BSU back in the late 1980s — was officially ...

In Tuesday night's Republican primary in West Virginia, Robert Karnes, a West Virginia Republican state senator who lashed out at teachers during their nine-day strike, lost to pro-labor candidate Bill Hamilton.

Lady Vols basketball relied on its best 3-point shooting night of the season to close out a win over Middle Tennessee State on Tuesday

Emerging research in nonhuman animals implicates cerebellar projections to the ventral tegmental area (VTA) in appetitive behaviors, but these circuits have not been characterized in humans. Here, we mapped cerebello-VTA white matter connectivity in a cohort of men and women using probabilistic tractography on diffusion imaging data from the Human Connectome Project. We uncovered the topographical organization of these connections by separately tracking from parcels of cerebellar lobule VI, crus I/II, vermis, paravermis, and cerebrocerebellum. Results revealed that connections between the cerebellum and VTA predominantly originate in the right cerebellar hemisphere, interposed nucleus, and paravermal cortex and terminate mostly ipsilaterally. Paravermal crus I sends the most connections to the VTA compared with other lobules. We discovered a mediolateral gradient of connectivity, such that the medial cerebellum has the highest connectivity with the VTA. Individual differences in microstructure were associated with measures of negative affect and social functioning. By splitting the tracts into quarters, we found that the socioaffective effects were driven by the third quarter of the tract, corresponding to the point at which the fibers leave the deep nuclei. Taken together, we produced detailed maps of cerebello-VTA structural connectivity for the first time in humans and established their relevance for trait differences in socioaffective regulation.

We used virus-mediated anterograde and retrograde tracing, optogenetic modulation, immunostaining, in situ hybridization, and patch-clamp recordings in acute brain slices to study the release mechanism and μ-opioid modulation of the dual glutamatergic/GABAergic inputs from the ventral tegmental area and supramammillary nucleus to the granule cells of the dorsal hippocampus of male and female mice. In keeping with previous reports showing that the two transmitters are released by separate active zones within the same terminals, we found that the short-term plasticity and pharmacological modulation of the glutamatergic and GABAergic currents are indistinguishable. We further found that glutamate and GABA release at these synapses are both virtually completely mediated by N- and P/Q-type calcium channels. We then investigated μ-opioid modulation of these synapses and found that activation of μ-opioid receptors (MORs) strongly inhibits the glutamate and GABA release, mostly through inhibition of presynaptic N-type channels. However, the modulation by MORs of these dual synapses is complex, as it likely includes also a disinhibition due to downmodulation of local GABAergic interneurons which make direct axo-axonic contacts with the dual glutamatergic/GABAergic terminals. We discuss how this opioid modulation may enhance LTP at the perforant path inputs, potentially contributing to reinforce memories of drug-associated contexts.

By the 1930s, the black middle class had arrived, with the purchasing power to match. Sensing an opportunity, developers established Idlewild: a summer resort aimed exclusively at African-Americans.

Paul Raffaele explores gorilla tourism, raising gorillas in captivity and the future of the Congo mountain gorillas

The world’s slowest mammal is at risk of extinction by the end of the century due to their low metabolic rate and climate change

The success is a giant leap toward the company's goal to take humans and cargo all the way to Mars on the world's biggest and most powerful launch vehicle

Paramotorists spotted the dog while soaring above one of Giza's pyramids last week

By analyzing an old lidar survey, researchers found evidence of more than 6,500 ancient structures in a previously unexplored area of Campeche

The 4,500-year-old pyramids of Giza are the backdrop for "Forever Is Now," which features sculptures, installations and immersive artworks that explore the relationship between the past and present

Facing soaring food prices and an escalating housing crisis, Quebec student associations are urgently calling on the provincial government to fund internships required for post-secondary training.

Families of Norton Elementary School won’t be seeing their kids return anytime soon. Repairs are going to take longer than expected and students are expected to be back in the school by the start of the next school year.

The Ontario Liberal Party is pledging to reduce the income tax rate for middle class families and eliminate provincial sales tax on hydro bills, if they win in the 2026 election.

Teacher: 'We're growing engineers here'

OM workers in North Africa explain they have peace even during times of political unrest.

MSC Mediterranean Shipping Company SA's Africa logistics unit will invest as much as €40 million in Namibia by 2030 to benefit from growing oil, gas and renewable energy developments.

The miner says Transnet knows full well where its own inefficiencies lie and it needs to start addressing these.

Despite criticism of electioneering, the Government Communication and Information System (GCIS) has defended its R7 million social-reality television show.

The rand slumped more than 2% on Monday as renewed concerns about China’s prospects hit metal prices and investors fretted about a possible trade war under US President-elect Donald Trump.