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HARMAN Unveils the HARMAN ExP Integrated Solution Suite at CES 2020 – Elevating Automotive Tech into Meaningful Consumer Driving Experiences

CES 2020 - LAS VEGAS, NV - JANUARY 6, 2020 – HARMAN, a wholly-owned subsidiary of Samsung Electronics Co., Ltd., focused on connected technologies for automotive, consumer and enterprise markets, today launched the HARMAN ExP Integrated Solution Suite,...




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The Future In-Car Experience and What It Means for Marketers




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Why dark matter's no-show could mean a big bang rethink

We can't find any trace of cosmic dark matter – perhaps because our models of the early universe are missing a crucial piece, says astrophysicist Dan Hooper




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Until the End of Time tries to use physics to find the meaning of life

Brian Greene's new book argues that life is rare and extraordinary, probably transient, and that in the search for purpose, the only significant answers are ones we create  




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Global warming is melting glaciers and that means more tsunamis

Mountainsides are becoming less stable as glaciers retreat, leading to more landslides that can trigger massive - but localised - tsunamis




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Climate change means nearly all glaciers in the Alps may disappear

A study of what will happen to glaciers in the Alps under various climate scenarios suggests they will almost completely disappear if we keep pumping out carbon dioxide




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When a smile is not a smile – what our facial expressions really mean

Smiling and other facial expressions aren't displays of feelings that transcend cultures but turn out to be full of hidden meaning




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We constantly eat microplastics. What does that mean for our health?

Tiny particles of plastic are in our food, water and even the air we breathe. We investigate the impact they have inside our bodies




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When a smile is not a smile – what our facial expressions really mean

Smiling and other facial expressions aren't displays of feelings that transcend cultures but turn out to be full of hidden meaning




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The sun is too quiet, which may mean dangerous solar storms in future

Stars that are similar to the sun in every way we can measure are mostly more active than the sun, which hints that the sun’s activity may ramp up someday, risking solar eruptions




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Less Money Means More Hurting

Title: Less Money Means More Hurting
Category: Health News
Created: 5/2/2008 2:00:00 AM
Last Editorial Review: 5/2/2008 12:00:00 AM




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Cat Allergy Doesn't Have to Mean Giving Up Kitty

Title: Cat Allergy Doesn't Have to Mean Giving Up Kitty
Category: Health News
Created: 4/23/2010 2:10:00 PM
Last Editorial Review: 4/26/2010 12:00:00 AM




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More Chocolate Means More Depression, or Vice Versa

Title: More Chocolate Means More Depression, or Vice Versa
Category: Health News
Created: 4/27/2010 11:41:00 AM
Last Editorial Review: 4/27/2010 11:41:12 AM




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Top 10 Food Trends: Hip May Not Mean Healthy

Title: Top 10 Food Trends: Hip May Not Mean Healthy
Category: Health News
Created: 4/26/2011 1:54:00 PM
Last Editorial Review: 4/26/2011 12:00:00 AM




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Cooking at Home Means Eating Better, Spending Less

Title: Cooking at Home Means Eating Better, Spending Less
Category: Health News
Created: 4/30/2017 12:00:00 AM
Last Editorial Review: 5/1/2017 12:00:00 AM




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Happy Mom Means Less Colicky Baby

Title: Happy Mom Means Less Colicky Baby
Category: Health News
Created: 4/28/2017 12:00:00 AM
Last Editorial Review: 5/1/2017 12:00:00 AM




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Mom's Money Worries May Mean Smaller Baby

Title: Mom's Money Worries May Mean Smaller Baby
Category: Health News
Created: 5/3/2017 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM




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Opioid Crisis Means More Newborns With Hepatitis C, But Few Get Tested

Title: Opioid Crisis Means More Newborns With Hepatitis C, But Few Get Tested
Category: Health News
Created: 5/2/2018 12:00:00 AM
Last Editorial Review: 5/2/2018 12:00:00 AM




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Earlier Mammograms May Mean Less Need for Aggressive Treatments

Title: Earlier Mammograms May Mean Less Need for Aggressive Treatments
Category: Health News
Created: 5/3/2018 12:00:00 AM
Last Editorial Review: 5/4/2018 12:00:00 AM




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High Measles Rates Mean Kids, Adults Need Proper Vaccination: CDC

Title: High Measles Rates Mean Kids, Adults Need Proper Vaccination: CDC
Category: Health News
Created: 4/29/2019 12:00:00 AM
Last Editorial Review: 4/30/2019 12:00:00 AM




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Red Tape Means Many Cancer Patients Get Radiation Treatments Late

Title: Red Tape Means Many Cancer Patients Get Radiation Treatments Late
Category: Health News
Created: 5/2/2019 12:00:00 AM
Last Editorial Review: 5/3/2019 12:00:00 AM




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With Macular Degeneration, 1 Missed Visit to Eye Doc Can Mean Vision Loss

Title: With Macular Degeneration, 1 Missed Visit to Eye Doc Can Mean Vision Loss
Category: Health News
Created: 2/7/2020 12:00:00 AM
Last Editorial Review: 2/10/2020 12:00:00 AM




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More Hot Flashes Could Mean Higher Odds for Heart Trouble

Title: More Hot Flashes Could Mean Higher Odds for Heart Trouble
Category: Health News
Created: 9/24/2019 12:00:00 AM
Last Editorial Review: 9/24/2019 12:00:00 AM




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Less Sex Could Mean Earlier Menopause

Title: Less Sex Could Mean Earlier Menopause
Category: Health News
Created: 1/15/2020 12:00:00 AM
Last Editorial Review: 1/16/2020 12:00:00 AM




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More Trees, Parks May Mean Longer Lives for City Dwellers

Title: More Trees, Parks May Mean Longer Lives for City Dwellers
Category: Health News
Created: 4/28/2020 12:00:00 AM
Last Editorial Review: 4/29/2020 12:00:00 AM




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Too Much Super Bowl Can Mean Too Little Sleep

Title: Too Much Super Bowl Can Mean Too Little Sleep
Category: Health News
Created: 1/31/2020 12:00:00 AM
Last Editorial Review: 1/31/2020 12:00:00 AM




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Family Values Means Covering Families: Parents Need to Focus on Parenting, Not Access to Care




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Targeting the polyamine pathway—“a means” to overcome chemoresistance in triple-negative breast cancer [Cell Biology]

Triple-negative breast cancer (TNBC) is characterized by its aggressive biology, early metastatic spread, and poor survival outcomes. TNBC lacks expression of the targetable receptors found in other breast cancer subtypes, mandating use of cytotoxic chemotherapy. However, resistance to chemotherapy is a significant problem, encountered in about two-thirds of TNBC patients, and new strategies are needed to mitigate resistance. In this issue of the Journal of Biological Chemistry, Geck et al. report that TNBC cells are highly sensitive to inhibition of the de novo polyamine synthesis pathway and that inhibition of this pathway sensitizes cells to TNBC-relevant chemotherapy, uncovering new opportunities for addressing chemoresistance.




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THE DECLARATION OF ASTANA AND WHAT IT MEANS FOR THE GLOBAL ROLE OF NAPCRG AND WONCA [Family Medicine Updates]




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What It Means to Live with Focal Segmental Glomerulosclerosis




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Age at Diagnosis and Patient Preferences for Treatment Outcomes in AML: A Discrete Choice Experiment to Explore Meaningful Benefits

Background:

The recent expansion of treatment options in acute myeloid leukemia (AML) has necessitated a greater understanding of patient preferences for treatment benefits, about which little is known.

Methods:

We sought to quantify and assess heterogeneity of the preferences of AML patients for treatment outcomes. An AML-specific discrete choice experiment (DCE) was developed involving multiple stakeholders. Attributes included in the DCE were event-free survival (EFS), complete remission (CR), time in the hospital, short-term side effects, and long-term side effects. Continuously coded conditional, stratified, and latent-class logistic regressions were used to model preferences of 294 patients with AML.

Results:

Most patients were white (89.4%) and in remission (95.0%). A 10% improvement in the chance of CR was the most meaningful offered benefit (P < 0.001). Patients were willing to trade up to 22 months of EFS or endure 8.7 months in the hospital or a two-step increase in long-term side effects to gain a 10% increase in chance of CR. Patients diagnosed at 60 years or older (21.6%) more strongly preferred to avoid short-term side effects (P = 0.03). Latent class analysis showed significant differences of preferences across gender and insurance status.

Conclusions:

In this national sample of mostly AML survivors, patients preferred treatments that maximized chance at remission; however, significant preference heterogeneity for outcomes was identified. Age and gender may affect patients' preferences.

Impact:

Survivor preferences for outcomes can inform patient-focused drug development and shared decision-making. Further studies are necessary to investigate the use of DCEs to guide treatment for individual patients.




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A lazy fix 20 years ago means the Y2K bug is taking down computers now

The millennium bug is back with a vengeance, after programmers in the 1990s simply pushed the problem back by 20 years




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What It Truly Means to ‘Believe Survivors’

Photo Illustration by Lyne Lucien/The Daily Beast/Getty

Two years ago, the voices of survivors of sexual harassment and assault launched an unprecedented movement the world over, using Tarana Burke’s MeToo framework. That one moment was a spark into the unknown, but the movement itself was no happy accident. It was built to fuel a reclamation of power for those who had been silenced for too long, a laborious undertaking by activists, advocates, and organizations including mine—the National Women’s Law Center, which also houses and administers the TIME’S UP Legal Defense Fund.

Since then, the #MeToo movement has enabled considerable progress, including making space for more and more people who have claims of sexual misconduct to come forward. People like Tara Reade.

But despite this dramatic cultural awakening, our institutions and systems are just beginning to stir. The lack of necessary legal and policy changes both in our government and in our workplaces, schools, houses of worship, and otherwise have created a world that very imperfectly serves the needs of survivors. Every domestic worker who is entirely unprotected by our federal and most state civil rights statutes, and every person who is classified as an independent contractor and left out of civil rights protections, have proven that our work must take on the reform and re-envisioning of the very systems that excluded them in the first place. 

Read more at The Daily Beast.




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The sun is too quiet, which may mean dangerous solar storms in future

Stars that are similar to the sun in every way we can measure are mostly more active than the sun, which hints that the sun’s activity may ramp up someday, risking solar eruptions




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RPGCast – Episode 398: “I Think You Mean Seven…?”

Today’s podcast has a feline bend, but we still aren’t the official Cat Fancy podcast. The full crew is here today with tons of games,...




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Estimates of the predicted coronavirus death toll have little meaning

With all the unknowns about covid-19, any numbers you hear about death tolls or how long restrictions will last should be taken not just with a pinch of salt but with a sack of it




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An unequal society means covid-19 is hitting ethnic minorities harder

People from an ethnic minority are disproportionately affected by covid-19. Researchers say the reasons are rooted in existing social and healthcare inequalities




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Keystone XL: police discussed stopping anti-pipeline activists 'by any means'

Revealed: records show law enforcement has called demonstrators possible ‘domestic terrorism’ threats

US law enforcement officials preparing for fresh Keystone XL pipeline protests have privately discussed tactics to stop activists “by any means” and have labeled demonstrators potential “domestic terrorism” threats, records reveal.

Internal government documents seen by the Guardian show that police and local authorities in Montana and the surrounding region have been preparing a coordinated response in the event of a new wave of protests opposing the controversial Keystone XL tar sands pipeline, which would carry crude oil from Canada to Montana, South Dakota and Nebraska.

Continue reading...




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Police hunt for swan killer after &apos;meaningless act of violence&apos;

A swan has died after being attacked in a "meaningless act of violence", police have said.




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America will put astronauts back on Moon by 2024 &apos;by any means necessary&apos;

American astronauts will be back on the Moon within five years "by any means necessary," the US Vice President has announced.




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Social distancing would mean &apos;1km queues at Heathrow for EACH plane&apos; airport boss warns

Social distancing at airports would lead to 1km-long queues for each jumbo jet, Heathrow's chief executive has claimed.




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Testing positive twice for Covid-19 does not mean people have been reinfected, World Health Organisation says

If someone tests positive for coronavirus more than once, it does not necessarily mean they have been reinfected, according to the World Health Organisation (WHO).




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&apos;Calculated&apos; thieves steal 80,000 face masks meant for NHS workers on coronavirus frontline

Heartless thieves have stolen 80,000 face masks from a Manchester warehouse which were meant to be used by NHS and frontline workers fighting coronavirus.




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Deleted tweet might mean a new campaign finance problem for Ilhan Omar




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&apos;Superfast&apos; new manufacturing method could mean breakthrough in battery technology, scientists say

'Reinvention' of ceramics firing process could be used by artificial intelligence to create new materials with wide range of possible applications






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What Would A Sharp Decline In Remittances Mean For Latin America

Immigrants in the U.S. sent an estimated $150 billion to their home countries in 2019 — half to Latin America and the Caribbean. The World Bank is predicting a sharp decline in remittances this year.




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Ben Fogle criticises &apos;mean-spirited&apos; people who mocked call for Britons to sing for the Queen

TV presenter's idea has been compared to Gal Gadot's star-studded coronavirus singalong video, which viewers labelled 'out-of-touch'




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Too Hot to Handle fan worked out what Kori Sampson&apos;s Roman numeral tattoo means

Show has proven to be a hit for Netflix