As demand for popular weight-loss drugs like Wegovy and Zepbound skyrockets, patients are taking dosage amounts into their own hands.

Diagnosing 'Stage One Alzheimer's Disease' based solely on biomarkers is potentially dangerous to patients.

In 1991, a young Atlanta Braves pitching sensation by the name of John Smoltz was 2-11 nearing the All Star break, and like with the Nationals' Stephen Strasburg, the baseball world was wondering what was wrong.

Sunday is the single biggest motorsports day in broadcast television history. NBC has the Grand Prix of Monaco at 7 a.m., coverage of the Indianapolis 500 starts at 11 a.m. on ABC and the nightcap at 6 p.m. will be the Coca Cola 600 from Charlotte on Fox. That means over 18 hours of live Formula 1, IndyCar and NASCAR action, making the Memorial Day weekend must-see TV for motorsports fans.

Capitals defenseman Jeff Schultz has requested a trade, according to his agent, Jarrett Bousquet.

That was some glorious return from the All-Star break for the Wizards, now wasn’t it? From the scoreboard that didn’t work, including the time and shot clock normally kept above the backboards, to Wale getting in a feud with the Toronto Raptors broadcasters, who called him a local rapper and said he was ‘no Drake,’ to the random “Jor-dan Craw-ford!” chant that sprang to life late as the Wizards failed to generate any consistent offensive flow and as Crawford himself remained reclined at the end of the bench throughout the game.

*Whatever the trade deadline and All-Star break did to disrupt the flow of the resurgent Wizards, they’re back. The idea of home wins over legitimate Western Conference teams Denver and Houston on back-to-back nights appeared daunting after the Wizards looked lethargic in their loss to Toronto earlier in the week. Instead, they proved they can still dictate how they want to play defensively over the course of 48 minutes against two teams with different kinds of significant offensive punch.

With their 90-84 win at Air Canada Centre on Monday, the Wizards sort of vindicated the notion that who they are now is a team that’s better on the road than their record (5-22) would indicate. I say “sort of” because that was the epitome of ugly. But it was also a game in which the Wizards never trailed by more than three points. As bad as they looked offensively at times (20 turnovers), they still had 23 assists on 34 field goals and made the Raptors, who shot 36.7 percent, look even worse.

There’ll be no more teasing with the standings after the Wizards lost, 96-95, to the Detroit Pistons. I’ll get to that in a sec, but first:

The Commodity Futures Trading Commission denied financial services firm Kalshi's bid to allow betting on control of Congress. Now the company is suing to overturn the decision.

The personal information of more than 200,000 people in Los Angeles County was potentially exposed after a hacker used a phishing email to steal login credentials.

The Gene Roddenberry foundation will award $1 million to an early-stage venture focused on harnessing artificial intelligence in service of humanity.

Along with Google and Facebook, the company has done more than most to undo privacy as we once knew it, creating an economy built on our personal data.

Big Tech titans such as Elon Musk and Reid Hoffman are divided between Kamala Harris and Donald Trump but all too united in their selfish aims. We need a new model.

E-commerce giant Amazon joins Google and other tech companies in investing in nuclear power they plan to use in the race to build new AI-powered products.

Mind-controlling fungi are changing the ways that scientists understand host-parasite relationships.

New 3D blueprints that highlight tumor complexity reveal several new discoveries, some of which challenge existing theories of cancer progression.

Optical density can be affected by sample conditions, the state of the measuring vessel, and instrument configuration.

Cellular oxygen consumption in the brain may shed new light on Alzheimer’s disease onset, progression, and treatment.

In this webinar, Alex Rimmer, Samuel East, and Catriona Jamieson will discuss how they developed low-cost, animal-free culture media for cellular agriculture.

Zymo Research believes that Qiagen’s lawsuit is part of a larger strategy to misuse litigation as a tool to stifle innovation and delay the adoption of groundbreaking technologies that benefit the scientific and medical communities.  

Microfluidic chips that mimic the complex human cervical environment provide a platform to study the reproductive tract and associated infections like bacterial vaginosis.

The steps leading up to the Lincoln Memorial were vandalized with a message that read “Free Gaza” in red paint.

Maybe it's a genuine sentiment. Maybe it's clouded by bitterness stemming from his one (failed) season in Washington. Regardless, former Redskins quarterback Donovan McNabb is not a fan of the zone read option.

The Wizards found out last week they will have the eighth-best odds (3.5 percent) to win next month's draft lottery after losing a tiebreaker with the Detroit Pistons. While they could leapfrog to the first, second or third pick, in an unlikely scenario they could fall as far as 11th.

Gio Gonzalez threw strikes on Thursday night – 78 to be exact, on 112 pitches — keying his one-hit work over eight dominant innings in the Nats’ 8-1 victory over the Reds. Gonzalez (2-1), the Nats’ starter most susceptible to wildness, had walked 11 in 20 innings, lasting no more than six innings in any of his previous four starts. But with the lead from the third inning on, Gonzalez was able to attack.

How rare was Jordan Zimmermann’s complete game shutout in Friday’s 1-0 win over the Reds? It was just the eighth for the Nats since moving to D.C. in 2005 and was the first complete-game one-hit shutout. Here are the Nats pitchers who have pitched complete-game shutouts.

More than a dozen people sustained injuries in an incident involving a Greyhound bus in Georgia, which local authorities said flipped on its side when one of the vehicle's tires blew out.

Jennifer Lopez wants D.C. to know she's still "Jenny From the Block," seeing as the multitasking superstar mentioned growing up in the Bronx within the first three minutes of her interview onstage Wednesday at the Cable Show taking place at the Washington Convention Center.

Left-wing activists may have fueled the movement to change the name of Washington’s NFL franchise. However, an indigenous organization known as the Native American Guardian’s Association is trying to resurrect its former moniker and make Washington’s football team the “Redskins” again. Now known as the Commanders, the team changed its name in 2020 to appease a fanatical mob of social justice warriors and white guilt apologists who claimed the name and logo were racist.

Steve Wozniak, co-founder of Apple, experienced a stroke during his trip to Mexico on Wednesday.

Small settlements scattered throughout the region show signs of trade, fortification.

Defenseman requests a fresh start elsewhere

WASHINGTON (AP) — Fool's errand or heroic stand?

Facebook and Instagram users in the EU users are getting a new option to use these platforms for free with less personalized ads, and Meta is also slashing the price of its ad-free subscription by 40%.

The post Facebook and Instagram to Display Less Personalized Ads in the EU to Appease Regulators appeared first on Thurrott.com.

I was excited to see Microsoft bring the Windows Presentation Foundation (WPF) back from the dead this past year: At Build 2024 back in May, it announced that it would continue investing in this 20-year-old technology, starting with support for Windows 11 theming that would arrive as part of .NET 9. In fact, I was so excited about this that I brought my .NETpad project back from the dead as well, and I spent much of the summer modernizing my Notepad clone with the new features. I wrote 24 articles documenting this work, but I was stymied by the half-assed nature of the improvements.

Microsoft released exactly one WPF update during the several months of .NET 9 development, and it never added any of the features I discovered were missing. And so as we headed into today's release of .NET 9, my excitement was somewhat diminished. My assumption was that we wouldn't see those missing features implemented until .NET 10, if ever.

Well, Microsoft just released .NET 9. As part of that release, it published updated documentation for WPF (and all the other .NET technologies). And to my surprise, there are some updates to WPF that address at least one of those missing features.

So let's take a look.

To add support for Windows 11 theming to a WPF project, you need to add a reference to the new Fluent theme resource dictionary in its App.xml file. It looks like so:

<Application.Resources>
    <ResourceDictionary>
      <ResourceDictionary.MergedDictionaries>
        <ResourceDictionary Source="pack://application:,,,/PresentationFramework.Fluent;component/Themes/Fluent.xaml" />
      </ResourceDictionary.MergedDictionaries>
    </ResourceDictionary>
</Application.Resources>

But with the shipping version of .NET 9, there's a second, more elegant way to add Windows 11 theming support. Now, you can access a new Application.ThemeMode property of a new styling API to toggle the app's theme mode between Light, Dark, System, and None. And that's fantastic, because it addresses one of those missing features: To date, .NETpad has adapted itself to the system theme (Light or Dark), but there was no way to let the user pick a theme mode. (For example, if the system was set to Dark and the user wanted the app to use Light mode.) With this change, I can implement that feature.

Fortunately, .NETpad is ready for this change, too: If you followed along with my work this past summer, you may remember that I implemented the user interface for switching the app theme into its settings interface, but left the UI hidden because it didn't do anything. But I always felt that Microsoft would need to implement this features, so I left the code in there. Granted, I didn't think it would happen this quickly.

The shipping version of .NET 9 also adds explicit support for the Windows 11 accent color (as configured by the user in the Settings app in Personalization > Accent color). As it is, .NETpa...

The post Modernizing .NETpad: .NET 9 Arrives with a Few (More) Small Improvements for WPF (Premium) appeared first on Thurrott.com.

Our news quiz is back and ready to roll, just in time for... well, a week that feels like it might be kind of important! by Sally Neumann & Leah Caglio

Well, something sure has happened. And frankly, if we have to read one more fact about that man and his sycophantic oligarchical cabal, we will lose our shit. So we’re going to do some radical self-care by cooking a cauldron of Strega Nona-style pasta and writing about all the joyful things, and scraps of progress we can find. Here are some (relatively! Low bar, but it’s what we have!) GOOD things to have come out of this election. Let’s start off with Washington: our very own Big Blue House. by Sally Neumann & Leah Caglio

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This week's rounds are Music (Intros), Cetaceans, Football Club Nicknames (Quickfire), Places and an extra Prize Round!
There is no music this week because of the prize round.
Prize Round Picture Question:

Which country?

This week's rounds are Music (Connections), Aviation, Famous Voices, and Music Too.
The music is Lady of My Dreams by Jay Tobin.

This week's rounds are Music (Themes), Julius Caesar, International Border Rivers (Quickfire), and the Natural World.
The music is Star Caesar from Possimiste.

This week's rounds are Music (Annual Anthems), Famous Roads, Languages, and Art.
The music is from Punk Rock Opera with a song called The Road.

This week's rounds are Music (Classical), Dragons, Cartoon Families (Quickfire), and Who Am I?
The music is Gone in the Wind by Dragon.

This week's rounds are Music (Connections), Atlanta, Movies and History.
The music is Peach Tree by Matteah Baim.

This week's rounds are Music (Mashup Madness), Trees in Literature, Animated Disney Movies (Quickfire), and Sport.
The music is from Springtide with the Teahouse and Bamboo Trees.

This week's rounds are Music (Annual Anthems), Microstates, Television, and Geography.
The music is Liechtenstein with Roses in the Park.

This week's rounds are Music (Christmas Songs), The Nativity, Food Origins (Quickfire), and Science and Technology.
The music is Greg Atkinson with Pantomime Cow.

This week's rounds are Music (Connection), 2019, Musical Instruments, and Literature.
The music is New Year A by Lobo Loco.

This week's rounds are Music (Intros), Dictionaries, Dog Idioms (Quickfire), Transport and an extra Prize Round!
There is no music this week because of the prize round.
Prize Round Picture Question:

Which letter of the Greek alphabet?

This week's rounds are Music (Annual Anthems), Copper, Famous Voices, and Television.
The music is Copper Kettle by Kathleen Martin.