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OM EAST and local partners raise a banner in Roma villages

This summer nearly 1,000 Roma children in Roma villages throughout Central and Eastern Europe heard the Gospel.




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Finland's grassroots paradise

We visit the winners of the Best Club category in the 2011 UEFA Grassroots Day Awards.




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Shareholders support FBB and recognise business plan / Application for temporary closure of Tegel is postponed until after Easter

Following yesterday´s Supervisory Board meeting and the meeting on 19 March 2020, yesterday´s FBB shareholders’ meeting dealt with the results of the meeting and confirmed its main decisions. The shareholders recognised the business plan approved by th...




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Fire safety and evacuation exercise at BER postponed until summer / No effect on commissioning

In light of the regulations on hygiene and gatherings in connection with the global corona pandemic, a fire safety and evacuation exercise, which was scheduled to take place on 29 April in Terminal T1 and the BER railway station, has been postponed yest...




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Coronavirus: Professor raises 'big problem' with Nicola Sturgeon's test, trace, isolate strategy

A PUBLIC health professor has warned that the Scottish Government’s strategy to escape the lockdown will encounter “a big problem” unless test results can be provided quicker.




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Italy’s coronavirus death toll rises above 30,000

Italy has become the first European Union country to record more than 30,000 coronavirus deaths.




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Fair Isle Bird Observatory to rise from the ashes

IT is one of he most important seabird observatories in the world, but its very future was called into question when fire ravaged through it and left it no more than a pile of rubble.




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David Torrance: The rise of political tribalism has little to do with policy and everything to do with identity

A couple of weeks ago, I attended an “in conversation” event with the American sociologist Arlie Russell Hochschild at Harvard University.




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Gerard Richardson: South African surprise led to discovery

ONE of the trying things about being a drinks columnist is the number of wines I have to taste in order to write this Shakespearian text for you guys. Products have to be really special to stand out from the crowd and, thankfully, they occasionally still do.




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SNP MP Steven Bonnar apologises over altercation with neighbour

SNP MP Steven Bonnar has apologised after a heated altercation with a neighbour.




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Music reviews: Drake flounders on a surprise mixtape of leaks and demos

DRAKE - DARK LANE DEMO TAPES




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Are Teachers' Unions on the Brink of Demise?

With the Janus case looming before the Supreme Court, teachers' unions are knocking on doors to try to boost membership and mitigate financial loss.




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Nicola Sturgeon "considering" relaxation of lockdown exercise restrictions

NICOLA Sturgeon could issue a change to the Scottish Government's policy on allowing outdoor exercise over the weekend - after Wales indicated the guidance will be relaxed from Monday.




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Praise Seen as Effective Classroom-Management Tool

When teachers use more praise and fewer reprimands in the classroom, it seems to help students stay on-task and behave better, according to a new study.




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Ed-Tech Supporters Promise Innovations That Can Transform Schools. Teachers Not Seeing Impact

Fewer than one-third of America's teachers say ed-tech innovations have changed their beliefs about what school should look like, according to a new Education Week survey.




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Cyberbullying Is on the Rise Among Teenagers, National Survey Finds

A growing number of students—especially girls—are experiencing bullying online, according to the latest federal data on bullying and crime in schools.




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Allowing people to be who and what they are, without fear of prejudice, is the hallmark of a civilised society

If you have never given your gender much thought, count yourself lucky. If that tick in the box on almost every form requires no more effort than a flick of the wrist, be aware that for many people gender is not so straightforward.




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How can we call ourselves civilised if we leave these poor refugee children to starve?

How desperate would you have to be to put your child onto a rubber dinghy and wave them off to the mercy of the world? It beggars belief that people are doing it but they are. Some are parents who can afford only one fare so they buy a way out for their child.




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How Coronavirus Is Jeopardizing Teacher Pay Raises

The momentum to raise teacher salaries in several states has ground to a halt amid fears of coronavirus’ massive economic blow.




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Herald View: We are all to blame for demise of high street

THE primary and ultimate responsibility for the parlous state of the high street lies with its customers, or former customers, since we are increasingly giving our custom to online retailers instead.




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The Promise of Interactive TV Ruined Online Advertising

It's resulted in a creepy Orwellian environment where Google, Facebook, Amazon, and others have replaced Big Brother.




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Cyberbullying On the Rise in U.S. Schools, Federal Report Finds

The report found that roughly a third of middle and high schools reported disciplinary problems stemming from cyberbullying at least once a week or daily.




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In praise of Scotland's fish farms. Opinion by Struan Stevenson

THE most recent onslaught on Scotland’s farmed salmon industry has come from The Sustainable Inshore Fisheries Trust, who commissioned a report from Salmon & Trout Conservation Scotland claiming that the value of farmed salmon to the Scottish economy, and the number of people it employs, are both massively overestimated by a staggering 251%. The success of Scotland’s aquaculture industry and its employment of large numbers in remote, rural parts, has always rankled with the industry’s crit




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Schuylkill Speaks: Abbie Kaiser leverages campus success into marketing job

Penn State Schuylkill senior Abigayle Kaiser has embraced leadership roles on campus throughout her undergraduate experience. From Schuylkill Benefitting THON, to the Lion Ambassadors, the Blue & White Society and so much more, Kaiser is a student who did it all. As she nears graduation with a full-time marketing job secured, Kaiser reflects on her time as a Penn Stater.




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Bilingual Education Poised for a Comeback in California Schools

Nearly 20 years after voting to restrict bilingual education in a state with more than 1 million schoolchildren who don't speak English as their first language, California voters appear poised to reverse that ban.




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Association Between Sexually Transmitted Diseases and Young Adults' Self-reported Abstinence

The extent to which young adults' laboratory-confirmed sexually transmitted disease results and self-reported sexual behaviors are consistent has not been assessed in a nationally representative sample.

The primary purpose of this study was to determine whether young adults' reports of recent sexual behavior (presence of penile/vaginal sex in the previous 12 months) correspond with the presence of laboratory-confirmed nonviral STDs assessed by nucleic acid amplification testing. (Read the full article)




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Distribution of and Mortality From Serious Congenital Heart Disease in Very Low Birth Weight Infants

There have been no previous large studies of congenital heart disease in very low birth weight infants.

This study characterized the frequency, mortality rate, and lesion distribution of serious congenital heart disease in very low birth weight infants by using a large international multicenter database. (Read the full article)




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Clustering of Risk Factors: A Simple Method of Detecting Cardiovascular Disease in Youth

Cardiovascular risk factors predict the development of premature atherosclerosis. As the number of risk factors increases, so does the extent of these lesions. Assessment of cardiovascular risk factors is an accepted practice in adults but is not used in pediatrics.

In this study, the authors discuss how the presence of ≥2 cardiovascular risk factors is associated with vascular changes in adolescents. The findings were compared with the Patholobiological Determinants of Atherosclerosis in Youth risk score to demonstrate that a simple method of clustering is a reliable tool to use in clinical practice. (Read the full article)




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Corticosteroid Pulse Combination Therapy for Refractory Kawasaki Disease: A Randomized Trial

The efficacy of intravenous immunoglobulin and corticosteroid pulse combination therapy for refractory Kawasaki disease has been established. The Egami score can be used to predict which patients are likely to have refractory Kawasaki disease.

As a new strategy for primary treatment, intravenous immunoglobulin and corticosteroid pulse combination therapy is safe and effective for patients predicted to have refractory Kawasaki disease based on the Egami score. (Read the full article)




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Clinical Characteristics and Risk Factors for Symptomatic Pediatric Gallbladder Disease

Gallbladder disease in children is an evolving entity and studies suggest an increasing frequency of symptomatic pediatric gallbladder disease and resultant cholecystectomies.

Hispanic ethnicity and obesity are epidemiologically significant risk factors for symptomatic gallbladder disease in the pediatric population. (Read the full article)




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Trivalent Inactivated Influenza Vaccine Is Not Associated With Sickle Cell Crises in Children

Children with sickle cell disease are at high risk of complications from influenza infection and have been recommended to receive annual influenza vaccine since the 1970s. Few safety studies, however, have examined the safety of influenza vaccine in this population.

This large cohort study did not find an association between influenza vaccination and hospitalization for sickle cell crises in children with sickle cell anemia. (Read the full article)




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Human Rhinoviruses in Severe Respiratory Disease in Very Low Birth Weight Infants

Human rhinovirus infections are common in children. Although historically associated with upper respiratory tract illness, rhinoviruses are increasingly recognized for their role in the exacerbation of asthma. Their role in bronchiolitis and severe lung disease in premature infants is unclear.

The authors of this study prospectively explore the role of rhinoviruses in premature infants using molecular techniques and identify these agents as the most frequent cause of hospitalization in this population. (Read the full article)




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Aerobic Capacity and Exercise Performance in Young People Born Extremely Preterm

Extreme preterm birth is associated with developmental shortcomings that may reduce exercise capacity and participation in physical activities in later life. The number of studies addressing these issues in adolescent populations is limited, test methods differ, and results are diverging.

Exercise capacity after preterm birth was in the same range as in term-born control subjects. Participation in physical activity was lower in preterm subjects compared with control subjects; however, the response to exercise in terms of increased aerobic capacity was similar. (Read the full article)




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Late Intravenous Immunoglobulin Treatment in Patients With Kawasaki Disease

The effectiveness of intravenous immunoglobulin treatment of patients with Kawasaki disease within 9 days of illness has been established. However, the effectiveness of such treatment ≥10 days after illness onset has not yet been clarified.

Intravenous immunoglobulin treatment ≥10 days after illness onset was observed to be effective for achieving inflammation resolution. Patients who are strongly suspected to have Kawasaki disease and demonstrate ongoing inflammation should therefore be treated as soon as possible. (Read the full article)




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What the Orphan Drug Act Has Done Lately for Children With Rare Diseases: A 10-Year Analysis

Rare diseases in childhood can be debilitating and require lifelong care. Since 1983, the Orphan Drug Act incentives have stimulated the development and significantly improved the availability of treatment products for patients with rare diseases.

We report an increasing pediatric orphan product designations and approvals from 2000 to 2009. The trend indicates that the Orphan Drug Act has continued to address this important unmet need. (Read the full article)




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Impact of Rotavirus Vaccine on Diarrhea-Associated Disease Burden Among American Indian and Alaska Native Children

In the prerotavirus vaccine era, diarrhea-associated hospitalization and outpatient rates among American Indian and Alaska Native children were higher than those among the general US population. Routine rotavirus vaccination has dramatically decreased rotavirus diarrhea burden in the general US population.

Decreases in diarrhea-associated hospitalization and outpatient rates among American Indian and Alaska Native children in postvaccine years were observed in all Indian Health Service regions, with declines greater in each subsequent year after vaccine introduction. (Read the full article)




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Intakes of Alcohol and Folate During Adolescence and Risk of Proliferative Benign Breast Disease

Alcohol consumption during adolescence and early adulthood has been associated with an increased risk of biopsy-confirmed benign breast disease (BBD), an established risk factor of breast cancer.

This is the first study to analyze the association between adolescent alcohol consumption and risk of biopsy-confirmed proliferative BBD by adolescent folate intake. The result provides no evidence for protective effects of adolescent folate intake on risk of alcohol-associated BBD. (Read the full article)




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Effect of Acculturation and Distance From Cardiac Center on Congenital Heart Disease Mortality

Disparities in outcomes of ethnic minority children have been reported, and have been ascribed to having barriers to access to health care. Minority parents have indicated that difficulties in access are because of problems with transportation and being non-English speaking.

This population-based study of Texas infants with severe congenital heart disease reports that neither home distance from a cardiac center nor Hispanic children having a Latin American–born parent were risk factors for first-year mortality. (Read the full article)




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Prevalence of Cardiovascular Disease Risk Factors Among US Adolescents, 1999-2008

Overweight and obese children have a higher prevalence of several cardiovascular disease (CVD) risk factors. There is growing evidence demonstrating that CVD risk factors present during childhood persist into adulthood.

US adolescents had no significant change in prehypertension/hypertension and borderline-high/ high low-density lipoprotein cholesterol prevalence from 1999–2000 to 2007–2008; however, prediabetes/diabetes increased by 14%. (Read the full article)




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A 4-Year Exercise Program in Children Increases Bone Mass Without Increasing Fracture Risk

Observation studies and short-term prospective intervention studies have shown that physical activity positively affects the accrual of bone mass and size during growth; however, fracture risk has not been evaluated.

This study reports the long-term results of a prospective intervention with increased physical activity at a population-based level and for the first time evaluated the clinical relevant end point, fracture risk. (Read the full article)




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Abnormalities of Vascular Structure and Function in Children With Perthes Disease

The causes of Perthes disease are unknown. There is considerable evidence that the disease has a vascular mechanism, although the nature of this is unknown. There is some suggestion that affected individuals may have a heightened cardiovascular risk in adulthood.

Children with Perthes disease have reduced vascular caliber, which is independent of body height, and abnormal functional vascular measures. These findings may be important in the mechanism of disease and may have implications on long-term vascular morbidity. (Read the full article)




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Early Vaccinations Are Not Risk Factors for Celiac Disease

Celiac disease is an immunologic disorder with autoimmune features. Sweden experienced an epidemic of celiac disease in infants (1984–1996). Early vaccinations might influence the risk for autoimmune diseases, and could potentially have contributed to celiac disease risk and the epidemic.

Early vaccinations within the national Swedish program are not risk factors for celiac disease, nor do changes over time contribute to explaining the Swedish epidemic. A protective effect by vaccination against tuberculosis (bacillus Calmette-Guérin) is suggested. (Read the full article)




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Pediatric Versus Adult Drug Trials for Conditions With High Pediatric Disease Burden

Many drugs are not approved for use in pediatric patients and there is limited evidence on their safety and efficacy in children. Furthermore, there is concern that the quality of pediatric trials is inferior compared with adult trials.

For conditions with a high disease burden in children, only a small proportion of clinical drug trials study pediatric patients. Most pediatric trials are not funded by industry, and the deficiency of evidence is largest in developing countries. (Read the full article)




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Haemophilus influenzae Type b Disease and Vaccine Booster Dose Deferral, United States, 1998-2009

Since the introduction of effective vaccines in the United States, the incidence of invasive Haemophilus influenzae type b (Hib) disease in children aged <5 years has decreased by 99%. In 2007, in response to limited vaccine supply, Hib booster doses were deferred for 18 months.

This review found no significant change in the incidence of invasive Hib disease in the United States during the booster dose deferral period, suggesting that booster dose deferral is a reasonable approach to Hib vaccine shortages in the short-term. (Read the full article)




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Unprovoked Status Epilepticus: The Prognosis for Otherwise Normal Children With Focal Epilepsy

The outcome of status epilepticus in children depends on the etiology. In otherwise normal children who have ≥1 episodes of unprovoked status epilepticus as part of the evolution of their epilepsy, the seizure and intellectual outcome is unclear.

Based on population-based data and 20 to 30 years’ follow-up of normal children with focal epilepsy, one-third with status epilepticus had recurrence of status. Reassuringly, intelligence, seizure control, and rate of remission were not altered compared with those without status epilepticus. (Read the full article)




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Status of the Pediatric Clinical Trials Enterprise: An Analysis of the US ClinicalTrials.gov Registry

There are limited data regarding the current status of the pediatric clinical trial enterprise.

Evaluation of the ClinicalTrials.gov data set allows description of the overall portfolio of clinical trials relevant to US children, which was previously not possible. (Read the full article)




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Factors Influencing Participation in a Population-based Biorepository for Childhood Heart Disease

Understanding human disease genomics requires large population-based studies. There is lack of standardization, as well as social and ethical concerns surrounding the consent process for pediatric participation in a biorepository.

The study identifies specific barriers to pediatric participation in biorepositories relative to adults, and proposes strategies to improve ethical and responsible participation of pediatric-aged patients in large-scale genomics and biorepository-driven research without significantly increasing research burden for affected families. (Read the full article)




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Cord Blood 25-Hydroxyvitamin D3 and Allergic Disease During Infancy

The rising burden of allergy is most evident in infancy, indicating the importance of early exposures. Reduced vitamin D status in pregnancy has been associated with atopy and respiratory outcomes, but there is less information on other early allergic outcomes.

Cord blood 25-hydroxyvitamin D3 concentrations <50 nmol/L were highly prevalent in an Australian population. Lower vitamin D levels were associated with increased risk of eczema at 12 months of age, whereas there was no association with sensitization or food allergy. (Read the full article)




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Growth in Children With Congenital Heart Disease

Children with congenital heart disease (CHD) are at increased risk for poor growth. Several factors may play a role in poor growth, including feeding difficulties, increased caloric requirements, and the effects of cardiac lesions on growth regulation.

In children with CHD, impaired growth as measured by weight, length, and head circumference occurs simultaneously rather than sequentially, supporting the theory that altered growth regulation likely plays an important role in the poor growth of children with CHD. (Read the full article)




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Exercise-Induced Wheeze, Urgent Medical Visits, and Neighborhood Asthma Prevalence

The prevalence of asthma and associated urgent medical visits vary dramatically across neighborhoods in New York City. Some, but not all, children with asthma wheeze when they exercise.

Exercise-induced wheeze was more common for asthmatic children living in neighborhoods with higher versus lower asthma prevalence. Because exercise-induced symptoms indicate a propensity for rapid-onset symptoms, this increased prevalence may contribute to the observed increase in urgent medical visits. (Read the full article)