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AI-Driven Liquid Biopsy Enhances Early Detection of Ovarian Cancer

Highlights: AI-powered liquid biopsy detects ovarian cancer early Combines DNA fragment analysis and biomarkers




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Transcutaneous Spinal Cord Stimulation for Children With Acute Flaccid Myelitis

Acute Flaccid Myelitis (AFM) is an uncommon but severe neurological disorder that causes bsudden paralysis in children/b. Researchers at the International




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Growing Threat of Nitrous Oxide to Public Health and Climate

Rising Nitrous Oxide emissions pose serious risks to public health and climate, contributing to respiratory issues and global warming. Immediate action is crucial.




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AI-Driven Liquid Biopsy Enhances Early Detection of Ovarian Cancer

A breakthrough AI-powered liquid biopsy combining cell-free DNA and protein biomarkers improves early detection of ovarian cancer, aiding in accurate screening.




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Transcutaneous Spinal Cord Stimulation for Children With Acute Flaccid Myelitis

Learn how Transcutaneous Spinal Cord Stimulation is revolutionizing treatment for children with Acute Flaccid Myelitis, offering improved mobility and hope.




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Eosinophils: A Hidden Threat to Heart Disease

Discover the impact of hypereosinophilia on heart health, focusing on eosinophilic heart disease (EHD) and its mechanisms.




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Valor Hospitality Partners And Campbell Gray Hotels Announce Strategic Initiative In The Middle East

Valor Hospitality Partners, a leading full-service global hospitality management company is launching a strategic partnership with Campbell Gray Hotels & Resorts. This collaboration marks a key milestone for both companies, focused on elevating Valor Hospitality’s management portfolio of luxury properties across the Middle East. The partnership aims to enhance operational efficiency, improve guest experiences and drive commercial success for Valor properties alongside Campbell Gray.




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Lopesan Hotel Group and Stoneweg Hospitality join forces to acquire Hotel Miguel Angel in Madrid

Lopesan Hotel Group, the leading hotel company from the Canary Islands, in partnership with the investment firm Stoneweg Hospitality, has acquired the Hotel Miguel Angel, previously owned by General Mediterranean Holding S.A SPF, an iconic luxury hotel in the heart of Madrid’s Paseo de la Castellana.




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Upscale and Upper Midscale Hotel Projects Dominate China’s Pipeline at Q3 2024, Commanding 59% of Total Construction Pipeline

In the Q3 2024 China Hotel Construction Pipeline Trend Report by Lodging Econometrics (LE), at the end of the quarter, China’s total hotel construction pipeline reached a record high project count of 3,853 projects with 703,312 rooms, up 4% by projects and 3% by rooms year-over-year (YOY).




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ONYX Hospitality Group Transforms Thailand’s The Tide Resort

ONYX Hospitality Group, a leading management company for hotels, resorts, serviced apartments, and luxury residences in Southeast Asia, has signed an agreement to manage Amari The Tide Bangsaen. This property, which is a significant transformation of The Tide Resort, and has been reimagined as Amari The Tide Bangsaen, is set to reveal its new look in the second quarter of 2025. Located in Thailand in the Chonburi Province, a region poised for significant economic growth, especially in tourism, this property reflects Amari’s commitment to delivering exceptional experiences in Thailand’s most promising destinations. With a focus on enhancing the guest experience to create memorable moments for Thai and international tourists, it is set to cater to a wide range of traveller needs and preferences across leisure and business segments On 7 November 2024, a signing ceremony for a business partnership agreement to manage Amari The Tide Bangsaen was held between Five Leader Group Co., Ltd. and...




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Indian stock market opens in red as consolidation phase continues

Sensex was trading at 78,260 after slipping 414 points and Nifty was trading at 23,706 after dropping 167 points.




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Shaheen Afridi reclaims top spot in ODI bowlers rankings

Pakistan's premier fast bowler Shaheen Afridi has reclaimed the No.1 position in the ICC Men's ODI Bowler Rankings, a spot he initially held during last year's Cricket World Cup in India.




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Swiggy-backed Rapido sees net loss at Rs 371 crore in FY24

Homegrown ride-sharing platform Rapido registered a net loss of Rs 371 crore last fiscal (FY24) from Rs 675 crore in FY23.




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Providing better healthcare biggest priority: PM Modi ahead of Darbhanga AIIMS inauguration

Prime Minister Narendra Modi on Wednesday reaffirmed the Centre's commitment to providing better healthcare and improving the living conditions of the countrymen.




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Jharkhand: Residents of Chuglu village in Gumla boycott voting over poor roads, civic amenities

The residents of Chuglu village in Gumla Assembly constituency boycotted the polling on Wednesday to protest against poor roads, streets and other civic amenities. They are frustrated over lack of basic and essential infrastructure in their villages.




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US President-elect Trump announces Kristi Noem as Homeland Security Secretary

US President-elect Donald Trump has selected South Dakota Governor Kristi Noem as his next Secretary of the Department of Homeland Security.




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Karnataka by-polls: Congress will win all three seats, claims CM Siddaramaiah

Karnataka Chief Minister Siddaramaiah on Wednesday expressed confidence that Congress party would win by-elections in all three constituencies of the state.




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No decision taken on Muslim reservation in awarding contracts: Siddaramaiah

Karnataka Chief Minister Siddaramaiah clarified that no decision has been taken on giving reservations to Muslims.




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Samastipur residents praise PM Modi for Jan Aushadhi Kendra

Prime Minister Narendra Modi visited Bihar on Wednesday, where he inaugurated, laid the foundation for, and dedicated several major development projects worth approximately Rs 12,100 crore.




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Navjot Singh Sidhu is back on Kapil Sharma's new show; netizens demand 'Justice for Archana Puran Singh'

Navjot Singh Sidhu's return on The Great Indian Kapil Show is expected to ruffle some feathers.




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Laapataa Ladies renamed as Lost Ladies: Aamir Khan, Kiran Rao host special screening amid Oscars campaign in NY

On November 12, a new poster for the film was revealed, accompanied by a caption that read, "Official entry: India. Best International Feature Film - 97th Academy Awards."




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Khushi Kapoor on dating amid relationship rumours with Vedang Raina; says 'keep personal life private'

The rumours of Khushi Kapoor and Vedang Raina dating have been going strong for a while now but the Archies co-stars have never publicly admitted to the same




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Did Kartik Aaryan ignore Tripti Dimri at Bhool Bhulaiyaa 3 success bash; netizens think so [Watch]

Speaking about the box-office clash, Bhushan Kumar said, "I am extremely happy for the love our film 'Bhool Bhulaiyaa 3' is receiving from the audience. It's been only a few days since the film hit the theatres and it has already done great business...Ya, I do feel the clash between (Bhool Bhulaiyaa 3 and Singham Again)"





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Businesses Are Reviving This 1800s Holiday Tradition With a 'Surprise and Delight' Factor That Drives Sales — Here's How One Buzzy Brand Is Making It Work

Brands like Straightaway Cocktails are putting their own spin on a practice you might remember from childhood.




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Spotify teases a ‘super premium’ tier for superfans and upcoming video expansion in Q3 earnings call

Spotify CEO Daniel Ek has once again teased the company’s long-delayed HiFi or “super premium” tier, a higher-qualify subscription offering the streaming service first announced in 2021 and then failed to roll out. In the company’s third-quarter earnings call with investors on Wednesday, the exec suggested that such a product was still on the way, […]

© 2024 TechCrunch. All rights reserved. For personal use only.




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Jawed Imam Siddiqui vs Directorate Of Enforcement on 13 November, 2024

1. By way of present bail application, the petitioner/applicant seeks regular bail in the proceedings emanating out of ECIR/35/DLZO/I/2022 dated 16.09.2022 which was registered on the basis of the FIR bearing No. 9A dated 23.11.2016 registered by the Central Bureau of Investigation (hereafter, the CBI), AC-III, New Delhi under Sections 120-B of IPC & 13(1)(d) r/w 13(2) of PC Act, 1988.

2. The allegations made in the aforesaid FIR, in nutshell, are that Mr. Amanatullah Khan, i.e. the main accused, in his tenure as chairman of the Delhi Waqf Board (hereafter, the „DWB‟), misused his position from March 2016 - October 2016 to appoint and engage relatives and other known persons to various posts in the DWB, from which they derived pecuniary benefits. It was further alleged that the tenancies of DWF properties were allotted without inviting bids and leased out only on reserve price. There were also allegations of misuse of DWB funds.




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M.B.K. Enterprises And Ors vs Saidpur Jute Co. Ltd. And Ors on 12 November, 2024

judgment and order dated 12 January 2023 passed by the Appellate Bench of the Small Causes Court dismissing (A-1) Appeal Nos.396/2015 and 95/2016 and confirming the eviction decree dated 25 June 2015 passed by the Small Causes Court in R.A.E. Suit No. 147A/306 of 1996. By decreeing the suit, the Small Causes Court has directed the Revision Applicants (Defendant Nos.1 to 8) to hand over possession of the suit premises to the Plaintiff.

B. FACTS 2) Plaintiff claims to be the owner of Godown No. 63 in

Sitaram Mill, Delisle Road, Mumbai-400 001 are the suit premises. By Agreement dated 2 July 1975 entered into between the Plaintiff- Saidpur Jute Co. Ltd and Defendant No.1-MBK Enterprises, Plaintiff granted lease in respect of portion of the Godown No. 63 admeasuring 8800 sq. ft (suit premises) in favour of Defendant No.1 for a period of 60 years at monthly rent of Rs.4,488/-. Plaintiff found Defendant No.2-Mid-Day Publications Pvt. Ltd. in occupation of the suit premises and accordingly filed R.A.E. Suit No. 147A/306 of 1996 on 9 February 1996 seeking recovery of possession of the suit premises on the grounds of (i) unlawful subletting by Defendant No.1 to Defendant No.2 (ii) commission of acts contrary to the provisions of Section 108 of the Transfer of Property Act and (iii) carrying out structural additions and alterations of permanent nature in the suit premises and erecting structures of permanent nature without 12 November 2024 Neeta Sawant CRA-120-2023-CRA-215-2023-FC obtaining written permission from Plaintiffs. Defendant No.1 appeared in the suit and filed Written Statement contending that under the covenants of lease, it was entitled to grant sublease in respect of the suit premises and that accordingly Defendant No.1 have subleased the premises to M/s. Mangla International Pvt. Ltd and Ors. who are associate companies having Directors from the same family and the said companies in turn had given the premises on license to Defendant No.2-Mid-Day. Defendant No.1 denied the allegations regarding to commission of act contrary to the provisions of section 108(o) of the Transfer of Property Act, as well as, erecting of structure of permanent nature without the consent of the landlord. Defendant No.2-Mid-Day also filed its Written Statement admitting its use and occupation of the suit premises from July 1995 but pleaded that such occupation was under agreement with Defendant No.1. Mid-Day also denied the allegations in the plaint.




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Vinod Mahabiprasad Gupta vs Saidpur Jute Co. Ltd. And Ors on 12 November, 2024

judgment and order dated 12 January 2023 passed by the Appellate Bench of the Small Causes Court dismissing (A-1) Appeal Nos.396/2015 and 95/2016 and confirming the eviction decree dated 25 June 2015 passed by the Small Causes Court in R.A.E. Suit No. 147A/306 of 1996. By decreeing the suit, the Small Causes Court has directed the Revision Applicants (Defendant Nos.1 to 8) to hand over possession of the suit premises to the Plaintiff.

B. FACTS 2) Plaintiff claims to be the owner of Godown No. 63 in

Sitaram Mill, Delisle Road, Mumbai-400 001 are the suit premises. By Agreement dated 2 July 1975 entered into between the Plaintiff- Saidpur Jute Co. Ltd and Defendant No.1-MBK Enterprises, Plaintiff granted lease in respect of portion of the Godown No. 63 admeasuring 8800 sq. ft (suit premises) in favour of Defendant No.1 for a period of 60 years at monthly rent of Rs.4,488/-. Plaintiff found Defendant No.2-Mid-Day Publications Pvt. Ltd. in occupation of the suit premises and accordingly filed R.A.E. Suit No. 147A/306 of 1996 on 9 February 1996 seeking recovery of possession of the suit premises on the grounds of (i) unlawful subletting by Defendant No.1 to Defendant No.2 (ii) commission of acts contrary to the provisions of Section 108 of the Transfer of Property Act and (iii) carrying out structural additions and alterations of permanent nature in the suit premises and erecting structures of permanent nature without 12 November 2024 Neeta Sawant CRA-120-2023-CRA-215-2023-FC obtaining written permission from Plaintiffs. Defendant No.1 appeared in the suit and filed Written Statement contending that under the covenants of lease, it was entitled to grant sublease in respect of the suit premises and that accordingly Defendant No.1 have subleased the premises to M/s. Mangla International Pvt. Ltd and Ors. who are associate companies having Directors from the same family and the said companies in turn had given the premises on license to Defendant No.2-Mid-Day. Defendant No.1 denied the allegations regarding to commission of act contrary to the provisions of section 108(o) of the Transfer of Property Act, as well as, erecting of structure of permanent nature without the consent of the landlord. Defendant No.2-Mid-Day also filed its Written Statement admitting its use and occupation of the suit premises from July 1995 but pleaded that such occupation was under agreement with Defendant No.1. Mid-Day also denied the allegations in the plaint.




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Vinod Mahabiprasad Gupta vs Saidpur Jute Co. Ltd. And Ors on 12 November, 2024

judgment and order dated 12 January 2023 passed by the Appellate Bench of the Small Causes Court dismissing (A-1) Appeal Nos.396/2015 and 95/2016 and confirming the eviction decree dated 25 June 2015 passed by the Small Causes Court in R.A.E. Suit No. 147A/306 of 1996. By decreeing the suit, the Small Causes Court has directed the Revision Applicants (Defendant Nos.1 to 8) to hand over possession of the suit premises to the Plaintiff.

B. FACTS 2) Plaintiff claims to be the owner of Godown No. 63 in

Sitaram Mill, Delisle Road, Mumbai-400 001 are the suit premises. By Agreement dated 2 July 1975 entered into between the Plaintiff- Saidpur Jute Co. Ltd and Defendant No.1-MBK Enterprises, Plaintiff granted lease in respect of portion of the Godown No. 63 admeasuring 8800 sq. ft (suit premises) in favour of Defendant No.1 for a period of 60 years at monthly rent of Rs.4,488/-. Plaintiff found Defendant No.2-Mid-Day Publications Pvt. Ltd. in occupation of the suit premises and accordingly filed R.A.E. Suit No. 147A/306 of 1996 on 9 February 1996 seeking recovery of possession of the suit premises on the grounds of (i) unlawful subletting by Defendant No.1 to Defendant No.2 (ii) commission of acts contrary to the provisions of Section 108 of the Transfer of Property Act and (iii) carrying out structural additions and alterations of permanent nature in the suit premises and erecting structures of permanent nature without 12 November 2024 Neeta Sawant CRA-120-2023-CRA-215-2023-FC obtaining written permission from Plaintiffs. Defendant No.1 appeared in the suit and filed Written Statement contending that under the covenants of lease, it was entitled to grant sublease in respect of the suit premises and that accordingly Defendant No.1 have subleased the premises to M/s. Mangla International Pvt. Ltd and Ors. who are associate companies having Directors from the same family and the said companies in turn had given the premises on license to Defendant No.2-Mid-Day. Defendant No.1 denied the allegations regarding to commission of act contrary to the provisions of section 108(o) of the Transfer of Property Act, as well as, erecting of structure of permanent nature without the consent of the landlord. Defendant No.2-Mid-Day also filed its Written Statement admitting its use and occupation of the suit premises from July 1995 but pleaded that such occupation was under agreement with Defendant No.1. Mid-Day also denied the allegations in the plaint.




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Commerzbank ia în considerare achiziționarea unui rival german pentru a respinge UniCredit

Commerzbank analizează opțiunea de a achiziționa o bancă germană de dimensiuni medii ca parte a strategiei de a evita o posibilă preluare de către UniCredit, potrivit Reuters. Planurile sunt într-o etapă incipientă, iar posibilele ținte ar putea include Hamburg Commercial Bank sau Oldenburgische Landesbank. Potrivit surselor Reuters, Commerzbank încearcă să conceapă un plan de apărare, ...

The post Commerzbank ia în considerare achiziționarea unui rival german pentru a respinge UniCredit appeared first on Forbes Romania.




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Vânzările globale de automobile electrice și hibride, în creștere cu 35% în octombrie

Vânzările globale de automobile complet electrice şi vehicule hibride de tip plug-in au crescut cu 35% în luna octombrie a acestui an comparativ cu aceeaşi lună a anului trecut, graţie în primul rând unui salt de 54% al vânzărilor de pe piaţa chineză, arată cifrele publicate de firma de cercetare de piaţă Rho Motion. Potrivit ...

The post Vânzările globale de automobile electrice și hibride, în creștere cu 35% în octombrie appeared first on Forbes Romania.




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A Mn(III)-catalyzed arylboronic acid-based cascade reaction via a nonclassical organometallic-radical mechanism

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00244J, Research Article
Hui-Min Qian, Jian-Dong Zhang, Shun-Jun Ji, Xiao-Ping Xu
An efficient Mn(III)-catalyzed cascade reaction of arylboronic acids, o-cyanoaryl isocyanides, and indoles was developed. The mechanism was fully investigated and elucidated.
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DBU-catalyzed substitution-controlled synthesis of oxa[3.3.1] bridged ring and naphthylamine derivatives

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00012A, Research Article
Shiyu Xu, Zhihui Sun, Pengyutian Liu, Yuanlin Wei, Fan Sun, Man Zhao, Ying Wang, Ming Zhang, Guofeng Li, Hong Liang
A switchable cascade cyclization reaction of ortho-alkynyl arylketones with amines has been developed, where the different reaction pathways are controlled by the substituent on the α-carbon of in-situ-generated ortho-alkynyl arylaldimines.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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DNA-compatible functional group transformations via K2RuO4-mediated oxidation

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00203B, Research Article
Pengyang He, Guixian Zhao, Mengping Zhu, Yangfeng Li, Gong Zhang, Yizhou Li
K2RuO4-mediated oxidation offers a DNA-compatible method for functional group transformations, enabling alcohol-to-carboxylic acid and amine-to-nitrile conversions valuable for DNA-encoded library synthesis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Palladium-catalyzed [4 + 4] cycloaddition of 2-pyrones with 2-alkylidenetrimethylene carbonates: access to bridged eight-membered oxygen heterocycles

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00329B, Research Article
Huawei Lin, Biming Mao, Bing Han, Jiayi Luo, Yanqing Ge, Xuerui Zhang, Chang Wang, Hongchao Guo, Chunhao Yuan
A novel palladium-catalyzed [4 + 4] cycloaddition of 2-pyrones with 2-alkylidenetrimethylene carbonates has been developed for the synthesis of bridged eight-membered oxygen heterocycles in good yields and with excellent stereoselectivities.
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Chiral guanidine catalyzed cyclization reactions of 1,3-enynes for lactone synthesis: switchable H-bond catalysis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00374H, Research Article
Yongyan Zhang, Lichao Ning, Tianxin Zhu, Zheng Xie, Shunxi Dong, Xiaoming Feng, Xiaohua Liu
Cyclization and 1,4-conjugate addition/cyclization between 2-activated 1,3-enynes and azlactones were achieved with chiral guanidine-amides for enol-type activation to yield a range of δ-lactone derivatives.
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Regio- and stereo-selective synthesis of β-phenylthio enamides via intramolecular 1,2-thiol migration

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D3QO02078A, Research Article
Yunqing Zhuang, Jin Zhang, Kai Yang, Gehua Bi, Xin Huang, Weimin Zhang
An efficient and novel method for the direct synthesis of β-phenylthio enamides via intramolecular 1,2-thiol migration has been developed.
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Review of application of the I2 and dimethyl sulfoxide combined reagent system to aryl methyl ketones for diverse transformations

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00396A, Review Article
Dong-Sheng Yang, Xiang-Long Chen, An-Xin Wu
The synthesis of small molecules and complex scaffolds is one of the most important topics in organic synthesis.
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Vaska's complex–PMHS combination enabled mild and chemoselective reduction of sulfoxides to sulfides with low catalyst loading

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00312H, Research Article
Fang-Fang Xu, Zhong-Lei Ruan, Pei-Qiang Huang
We report a highly efficient, versatile, and chemoselective method for the catalytic reduction of sulfoxides to sulfides under mild conditions.
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Decarbonylative C(sp2)–C(sp2) reductive cross-coupling of aroyl fluorides with aryl bromides by palladium/cobalt co-catalysis

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00305E, Research Article
Chen He, Zhiyong Song, Wei Yao, Rui Lin, Yuanhong Ma
Herein, we report a decarbonylative C(sp2)–C(sp2) reductive cross-coupling of aroyl fluorides with aryl bromides by palladium and cobalt co-catalysis.
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Electrochemically dehydrogenative C(sp2)–H/S–H cross-coupling: efficient synthesis of ortho-aminophenyl thioglycoside derivatives

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00171K, Research Article
Li-Yan Hu, Li Zhu, Shen-Yuan Zhang, Yu-Xin Guo, Yuan Li, Jie Zhu, Lei Wu
A method has been reported for synthesizing aryl thioglycosides through direct electrocatalytic dehydrogenative C(sp2)–H/S–H cross-coupling.
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Iodine-catalyzed intermolecular 1,2-thio (seleno)amination of alkenes with 1,2,3-triazoles and disulfides (diselenides) in air

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00246F, Research Article
Jian Ji, Xuwen Chen, Zongjing Hu, Cong Guan, Jinhua Liu, Yaqi Deng, Shunying Liu
Iodine-catalyzed 1,2-thio (seleno)amination of alkenes via direct N- and C-centered radical cross-coupling was established to elicit highly regioselective β-triazolized thioalkyl compounds.
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Spiro-centre substitution effects in the intramolecular spin–spin interactions of spirobiacridine diradicals

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00419A, Research Article
Open Access
Shinichi Ogawa, Takuya Kanetomo, Masaya Enomoto
Spirodiradicals with the Si and Ge spiro atoms exhibit a S = 1 state. The magnetic interaction in the Si derivative was found to be lower than that in the Ge derivative, implying a negative effect on σ*(Si–Cα)–π* hyperconjugation.
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Three-component Friedel–Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(III) electrophile

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00489B, Research Article
Open Access
Jun Kikuchi, Toya Nagata, Shingo Ito, Naohiko Yoshikai
A three-component Friedel–Crafts type difunctionalization of ynamides with an iodine(III) electrophile and electron-rich (hetero)arenes has been developed, enabling regio- and stereoselective synthesis of densely functionalized enamides.
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Metal-Free Cascade O-H Double Insertion Between I(III)/S(VI)-Ylides, Carboxylic Acids, and Alcohols: Modular Access to Unsymmetrical α,α-O,O-Substituted Ketones

Org. Chem. Front., 2024, Accepted Manuscript
DOI: 10.1039/D4QO00453A, Research Article
Shang-Shi Zhang, Jiaohang Wei, Wen-Xuan Zou, Qiong Hu, Mei-Zhu Bao, Dan-Ting Shen, Lin Xiao, Jia-Lin Song, Xiang Liu
The synthesis of unsymmetrical α,α-O,O-substituted ketones via O-H double insertion is appealing but remains constrained due to the lack of compatible coupling partners or uncontrollable selectivity. Herein, we present a...
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Visible-light-mediated catalyst-free synthesis of trifluoromethyl(spiro)-epoxides bearing contiguous quaternary centers

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO00184B, Research Article
Jingchuan Lin, Yu Zhang, Jinxin Wang, Xinyu Han, Shenglan Zhu, Tong Li, Yanping Zhu, Wei-Dong Zhang
Herein, we describe a non-covalent complex-mediated epoxidation strategy that can yield highly selective central spiro-epoxides by irradiation with visible light without the need for catalyst addition.
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Sulfamide instead of urea in Biginelli reaction: from black box to reality

Org. Chem. Front., 2024, 11,2155-2160
DOI: 10.1039/D3QO01926H, Research Article
Alexander Yu. Lyapunov, Andriy V. Tarnovskiy, Sergey Yu. Boron, Eduard B. Rusanov, Galyna P. Grabchuk, Dmytro M. Volochnyuk, Serhiy V. Ryabukhin
The scope and limitations of the classical Biginelli reaction have been expanded to principally novel substrates: sulfamide and its monosubstituted analogues.
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Unprecedented single-electron-transfer reduction-based N → C acyl migration reactions of imides enabled by redox-neutral photocatalysis

Org. Chem. Front., 2024, 11,2344-2350
DOI: 10.1039/D3QO01955A, Research Article
Linge Huai, Li Zhang, Zhentao Wang, Yewen Fang
N → C acyl migration: in the absence of a base, redox-neutral photocatalyzed acyl migration reactions have been realized via the reaction of N-vinylimides with alkyl radicals derived from alkyl silicates.
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Stereoselective skeletal modification of tryptanthrins to install chiral piperidine-2-ones enabled by Brønsted acid catalysis

Org. Chem. Front., 2024, 11,2171-2177
DOI: 10.1039/D3QO02029K, Research Article
Rong Zeng, Xiang Zhang, Yuan-Yuan Lei, Zhuo-Zhuo Zhang, Min Jiang, Qing-Zhu Li, Jun-Long Li, Bo Han
An asymmetric formal [4 + 2] cyclisation between azlactones and aza-dienes derived from simple tryptanthrins has been developed. With this established protocol, yielding a series of novel piperidine-2-one-fused tryptanthrins with up to >99 : 1 er under mild conditions.
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