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Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect




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Gene therapy for cardiovascular diseases in China: basic research




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Advances in genome editing: the technology of choice for precise and efficient β-thalassemia treatment




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Natural polyphenol assisted delivery of single-strand oligonucleotides by cationic polymers




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Homeostasis and regulation of autoreactive B cells




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Albumin fusion with granulocyte-macrophage colony-stimulating factor acts as an immunotherapy against chronic tuberculosis




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Microwave ablation of primary breast cancer inhibits metastatic progression in model mice via activation of natural killer cells




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Genomic profiling of intestinal T-cell receptor repertoires in inflammatory bowel disease




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The lysine methyltransferase SMYD2 is required for normal lymphocyte development and survival of hematopoietic leukemias




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IL12B and IL23R polymorphisms are associated with alopecia areata




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A year-long extended release nanoformulated cabotegravir prodrug




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Evaluation of glucocorticoid-induced TNF receptor (GITR) expression in breast cancer and across multiple tumor types




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Adenomyoepithelial tumors of the breast: molecular underpinnings of a rare entity




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<i>RAF1</i> rearrangements are common in pancreatic acinar cell carcinomas




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Mucinous carcinoma with micropapillary features is morphologically, clinically and genetically distinct from pure mucinous carcinoma of breast




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The impact of 2018 ASCO-CAP HER2 testing guidelines on breast cancer HER2 results. An audit of 2132 consecutive cases evaluated by immunohistochemistry and in situ hybridization




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<i>KRAS</i> amplification in metastatic colon cancer is associated with a history of inflammatory bowel disease and may confer resistance to anti-EGFR therapy




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Identification of gene modules associated with survival of diffuse large B-cell lymphoma treated with CHOP-based chemotherapy




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Combining clinical and candidate gene data into a risk score for azathioprine-associated leukopenia in routine clinical practice




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Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment




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Association of <i>MICA</i>-129Met/Val polymorphism with clinical outcome of anti-TNF therapy and MICA serum levels in patients with rheumatoid arthritis




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Publisher Correction: ASPI: a public–private partnership to develop treatments for autism




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Tumours use NETs as physical shields




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Gasdermin D inhibitor protects against sepsis




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Fibroblasts orchestrate tumour initiation




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Author Correction: From melanocytes to melanomas




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Automating Bias

How algorithms designed to alleviate poverty can perpetuate it instead




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Measure for Measure

Officials will vote to overhaul the standard system of scientific measurements




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Fixing Wasting Muscles

Scientists edited dogs' genes to correct a common form of muscle dystrophy




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Daily briefing: How desperate measures might shorten the coronavirus vaccine timeline — and at what risk




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Daily briefing: Convalescent serum — the antibody-laden blood of survivors — lines up as first-choice treatment for coronavirus




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Coronavirus in charts: historical funding for coronavirus research has been tiny




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Composition-dependent thermodynamics of intracellular phase separation




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Tunable correlated states and spin-polarized phases in twisted bilayer–bilayer graphene




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Laser spectroscopy of pionic helium atoms




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Daily briefing: Closest black hole ever discovered was ‘hiding in plain sight’




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Detection of metastable electronic states by Penning trap mass spectrometry




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Podcast: Galileo and the science deniers, and physicists probe the mysterious pion




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Unmasking the Tully Monster: fossils help to tackle a decades-old mystery




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Statin therapy is associated with lower prevalence of gut microbiota dysbiosis




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Mass spectrometry for future atomic clocks




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Basement membrane remodelling regulates mouse embryogenesis




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China is promoting coronavirus treatments based on unproven traditional medicines




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Identification of type 2 diabetes loci in 433,540 East Asian individuals




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Ancient Andean cities boasted cosmopolitan residents




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YTHDF2 promotes the liver cancer stem cell phenotype and cancer metastasis by regulating OCT4 expression via m6A RNA methylation




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Breaking through the glioblastoma micro-environment via extracellular vesicles




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HSP47 promotes metastasis of breast cancer by interacting with myosin IIA via the unfolded protein response transducer IRE1α




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Leucine-rich repeat containing 4 act as an autophagy inhibitor that restores sensitivity of glioblastoma to temozolomide




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The β-catenin/TCF-4-LINC01278-miR-1258-Smad2/3 axis promotes hepatocellular carcinoma metastasis