After taking the lead through Scott Malone, the Rams were denied a penalty when Martyn Waghorn appeared to be felled by Joe Bennett only for referee Darren England to wave away appeals.

TALK OF THE TOWN: The Don't Start Now singer says she has come 'completely off' Twitter to take one route of attack away from the keyboard warriors.

She welcomed her first child, a son named Oscar, with husband Peter Stefanovic on February 6.

The actress and the Jonas Brothers singer kept their looks casual as they went out for a walk. Sophie appeared to have Joe's hand tightly clasped in her own the whole time.

Threats of rape, kidnap and stripping have become commonplace against women on the Internet. Is it because of the limits of law itself or the fact that very few women seek legal recourse in such matters? Vaishnavi Vittal explores.

Seventeen years after the Supreme Court ruled that the government cannot restrict content on radio, it remains impossible for independent news to be aired on radio channels. Navya P K reports.

The feature lets users browse through groups divided into 25 categories such as parenting, sports, food, buy & sell and more. Each topic page highlights the top suggested groups, based on popularity and group members that users might already know.

Singers such as Mick Jagger, Paul McCartney, James Brown, Otis Redding, David Bowie and Rod Stewart have cited Little Richard as an influence.

Bade Achhe Lagte Hain fame Chahatt Khanna is a single mother with two beautiful girls, Zohar and Amaira. Recently, the actress lashed out at online trolls criticising her for being a single mother. She shared a few notes on her Instagram

Actress turned politician Nagma has found herself in trouble as she has been accused of being anti-India for siding with journalists from Pakistan. The actress is now getting trolled on Twitter for her tweet supporting the journalists. More than 10,000 tweets

Little Richard, the self-proclaimed "architect of rock 'n' roll" who built his ground-breaking sound with a boiling blend of boogie-woogie, rhythm and blues and gospel, died on Saturday at the age of 87.

Little Richard, the self-proclaimed "architect of rock 'n' roll" who built his ground-breaking sound with a boiling blend of boogie-woogie, rhythm and blues and gospel, died on Saturday at the age of 87.

Little Richard, the self-proclaimed "architect of rock 'n' roll" who built his ground-breaking sound with a boiling blend of boogie-woogie, rhythm and blues and gospel, died on Saturday at the age of 87.

Archives, Room Use Only - TK1.I42 1939

His 1955 song Tutti Frutti helped the genre enter American life

‘I am not sure we even have a choice’

A black chapter in the exploitation of farmers: Surjewala.

The Kozhikode Corporation Council has gone back on its decision to hand over the project for renovation of Muthalakkulam grounds to Salim Group and As

Little Richards died on Saturday at the age of 87

A furnace that covers the temperature range from room temperature up to 2000 K has been designed, built and implemented on the D2AM beamline at the ESRF. The QMAX furnace is devoted to the full exploration of the reciprocal hemispace located above the sample surface. It is well suited for symmetric and asymmetric 3D reciprocal space mapping. Owing to the hemispherical design of the furnace, 3D grazing-incidence small- and wide-angle scattering and diffraction measurements are possible. Inert and reactive experiments can be performed at atmospheric pressure under controlled gas flux. It is demonstrated that the QMAX furnace allows monitoring of structural phase transitions as well as microstructural evolution at the nanoscale, such as self-organization processes, crystal growth and strain relaxation. A time-resolved in situ oxidation experiment illustrates the capability to probe the high-temperature reactivity of materials.

Afamin, which is a human blood plasma glycoprotein, a putative multifunctional transporter of hydrophobic molecules and a marker for metabolic syndrome, poses multiple challenges for crystallographic structure determination, both practically and in analysis of the models. Several hundred crystals were analysed, and an unusual variability in cell volume and difficulty in solving the structure despite an ∼34% sequence identity with nonglycosylated human serum albumin indicated that the molecule exhibits variable and context-sensitive packing, despite the simplified glycosylation in insect cell-expressed recombinant afamin. Controlled dehydration of the crystals was able to stabilize the orthorhombic crystal form, reducing the number of molecules in the asymmetric unit from the monoclinic form and changing the conformational state of the protein. An iterative strategy using fully automatic experiments available on MASSIF-1 was used to quickly determine the optimal protocol to achieve the phase transition, which should be readily applicable to many types of sample. The study also highlights the drawback of using a single crystallographic structure model for computational modelling purposes given that the conformational state of the binding sites and the electron density in the binding site, which is likely to result from PEGs, greatly varies between models. This also holds for the analysis of nonspecific low-affinity ligands, where often a variety of fragments with similar uncertainty can be modelled, inviting interpretative bias. As a promiscuous transporter, afamin also seems to bind gadoteridol, a magnetic resonance imaging contrast compound, in at least two sites. One pair of gadoteridol molecules is located near the human albumin Sudlow site, and a second gadoteridol molecule is located at an intermolecular site in proximity to domain IA. The data from the co-crystals support modern metrics of data quality in the context of the information that can be gleaned from data sets that would be abandoned on classical measures.

A gas- and vapour-pressure control system synchronized with the continuous data acquisition of millisecond high-resolution powder diffraction measurements was developed to study structural change processes in gas storage and reaction materials such as metal organic framework compounds, zeolite and layered double hydroxide. The apparatus, which can be set up on beamline BL02B2 at SPring-8, mainly comprises a pressure control system of gases and vapour, a gas cell for a capillary sample, and six one-dimensional solid-state (MYTHEN) detectors. The pressure control system can be remotely controlled via developed software connected to a diffraction measurement system and can be operated in the closed gas and vapour line system. By using the temperature-control system on the sample, high-resolution powder diffraction data can be obtained under gas and vapour pressures ranging from 1 Pa to 130 kPa in temperatures ranging from 30 to 1473 K. This system enables one to perform automatic and high-throughput in situ X-ray powder diffraction experiments even at extremely low pressures. Furthermore, this developed system is useful for studying crystal structures during the adsorption/desorption processes, as acquired by millisecond and continuous powder diffraction measurements. The acquisition of diffraction data can be synchronized with the control of the pressure with a high frame rate of up to 100 Hz. In situ and time-resolved powder diffraction measurements are demonstrated for nanoporous Cu coordination polymer in various gas and vapour atmospheres.

The room-temperature experiment has been revisited for macromolecular crystallography. Despite being limited by radiation damage, such experiments reveal structural differences depending on temperature, and it is expected that they will be able to probe structures that are physiologically alive. For such experiments, the humid-air and glue-coating (HAG) method for humidity-controlled experiments is proposed. The HAG method improves the stability of most crystals in capillary-free experiments and is applicable at both cryogenic and ambient temperatures. To expand the thermal versatility of the HAG method, a new humidifier and a protein-crystal-handling workbench have been developed. The devices provide temperatures down to 4°C and successfully maintain growth at that temperature of bovine cytochrome c oxidase crystals, which are highly sensitive to temperature variation. Hence, the humidifier and protein-crystal-handling workbench have proved useful for temperature-sensitive samples and will help reveal temperature-dependent variations in protein structures.

A new temperature-controllable humidifier for X-ray diffraction has been developed. It is shown that the humidifier can successfully maintain protein crystal growth at a temperature lower than room temperature.

The effects of relative humidity on a tetragonal crystal form of hen egg white lysozyme are studied via in situ laboratory X-ray powder diffraction.

This article presents the capability of the QMAX furnace, devoted to reciprocal space mapping through X-ray scattering at high temperature up to 2000 K.

Rock ’n’ roll musicians live forever in the mind’s eye thanks to iconic photos of them in their element, playing live: Chuck Berry and his […]

The post What makes a great rock ’n’ roll photo? appeared first on Smithsonian Insider.

Forget what you thought you knew about geology. Some minerals can roll up like flaky Belgian piroulines. For the last several decades, mining operations in […]

The post Rolled-Up Mystery Mineral may cause Craving for Piroulines appeared first on Smithsonian Insider.

(The Paypers) Fenergo, a provider of digital Client Lifecycle Management (CLM) software solutions for...

Apr 8, 2020; 133:e0702-e0702
RESEARCH HIGHLIGHT

The U.S. Environmental Protection Agency (EPA) carries out experiments in which volunteer participants agree to be intentionally exposed by inhalation to specific pollutants at restricted concentrations over short periods to obtain important information about the effects of outdoor air pollution on human health.

U.S. colleges and universities should respond with urgency to the current surge in undergraduate enrollments in computer science courses and degree programs, which is straining resources at many institutions, says a new report from the National Academies of Sciences, Engineering, and Medicine.

PFAS, or perfluoroalkyl and polyfluoroalkyl substances, are ubiquitous fluorinated organic compounds found widely in manufactured products, from firefighting foam to stain-resistant carpets. These water- and oil-repellent compounds are known to degrade slowly over time, and have been found in humans, drinking water, and even in Arctic ecosystems.

On Broad Beach in Malibu, high tide not only wets sand but also retaining walls and broken down rock revetments. What happens next in homeowners' efforts to get sand trucked in here will go to the State Lands Commission - and the next Controller likely will weigh in on the problem. ; Credit: Molly Peterson/KPCC

The most common question I’ve been asked about the statewide Controller race this election year is the same question I get every four years. “Wait, we have one?”

The inevitable follow-up question: “What does this person do?” Down-ballot races in California’s state election can seem like a tedious part of a the voting process. Most of us just don't take the time to research them. In 2010, the last time we elected statewide executives, 435,308 of those people who voted for Governor just didn’t bother to vote for anybody in the Controller race. 

But in addition to being the chief fiscal officer of the 8th-largest economy in the world, the Controller sits on something like 80 state commissions and boards. And if you’re interested in California’s environment, a biggie there is the State Lands Commission.

The State Lands Commission oversees roughly 4 million acres of submerged land and tidelands, holding them in trust for the public. Right now it's looking at policy alternatives to respond to sea level rise. It manage the state's offshore oil-drilling leases. It even gets authority over historical shipwrecks! 

Three issues coming before to the Lands Commission mean the Controller matters:  

• Coastal Access and Martin’s Beach: At the end of September, Governor Jerry Brown signed a law requiring the State Lands Commission to negotiate with Vinod Khlosa, a private property owner who famously shut down coastal access over his land this year. The commission has all of next year to negotiate with Khlosa. If no deal is reached, it can use eminent domain authority to force public access – something that would represent a big break in historical practice, because that authority hasn’t ever been used in the 76 years that the commission has existed.
• Malibu’s Broad Beach has been rapidly eroding under pressure of waves and storms worsened by climate change, and very rich homeowners there have been seeking to add sand in front of their houses to combat the risk of damage to very expensive properties. Earlier this year, those homeowners successfully completed an application to the State Lands Commission, and the commission was expected to decide on it in October. The decision’s been put over till after the election.
• Fracking: Offshore oil made news late last year and earlier this year when some operators didn’t report that they were using drilling and production techniques collectively referred to as hydraulic fracturing. The news prompted the EPA to require chemical disclosures for drilling operations it oversees.  The state agencies that should be overseeing these issues – the Coastal Commission and the Lands Commission – are considering their next moves too.

Positions on these issues don’t really come up when it comes to the Controller race, though both Betty Yee and Ashley Swearengin have gone on the record to say they’re against fracking. 

This content is from Southern California Public Radio. View the original story at SCPR.org.

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Justin Timberlake and Anna Kendrick in Trolls World Tour.; Credit: Universal Pictures/Trolls World Tour (2020)

Larry Mantle and KPCC film critics Lael Loewenstein, Amy Nicholson and Charles Solomon review this weekend’s new movie releases and share some of their recommendations for movies and TV shows to discover, rediscover and binge-watch while you’re at home.

• "Trolls World Tour" on VOD (Vudu, FandangoNOW, AppleTV, Amazon Prime Video , Microsoft Store & more)

• "The Quarry" on VOD (FandangoNOW, Google Play, DirecTV On Demand)

• "A White, White Day" on The Frida Virtual Cinema

• "Away" on Laemmle's Virtual Cinema and Amazon Prime Video

• "Selah And The Spades" on Amazon Prime Video

• "The Booksellers" on VOD (Google Play) and virtual cinemas, including Laemmle's and The Virutal Frida Cinema

• "Endings, Beginnings" on VOD (iTunes and FandangoNOW)

• "Sergio" on Netflix

Want to see what our critics are watching and recommending you watch during stay at home? Click here to see a full list of our FilmWeek critics' favorite TV shows and films to binge-watch during COVID-19.

Guests:

Amy Nicholson, film critic for KPCC, film writer for The Guardian and host of the podcasts ‘Unspooled’ and the podcast miniseries “Zoom”; she tweets @TheAmyNicholson

Lael Loewenstein, KPCC film critic and film columnist for the Santa Monica Daily Press; she tweets @LAELLO

Charles Solomon, film critic for KPCC, Animation Scoop and Animation Magazine

This content is from Southern California Public Radio. View the original story at SCPR.org.

Assessing the potential of new environmental management tools often brings an ???innovation dilemma???: is it better to stick with what is known to work, or to implement new measures that are potentially more effective, but also more uncertain? Researchers have proposed an approach to deal with these dilemmas, and applied it to the case study of an invasive species programme in the US.

The North American pine wood nematode (PWN), Bursaphelenchus xylophilus, is a pest worm species that causes a disease known as pine wilt. It was discovered for the first time in the EU in Portuguese forests in 1999. Today, the entire territory of Portugal is demarcated for the presence of PWN, with a 20 km buffer zone, free from the pest, established along the Spanish border with the aim of preventing its further spread. The spread and establishment of PWN in the rest of EU territory is very likely if no strict measures are taken, as required by Decision 2012/535/EU of the European Commission, with serious economic and environmental consequences. To date, Spain has experienced five outbreaks of PWN, three of which have been successfully eradicated thanks to the EU measures and the effective work of the Spanish forest administration; and two outbreaks are currently being eradicated.

Assessing the potential of new environmental management tools often brings an ‘innovation dilemma’: is it better to stick with what is known to work, or to implement new measures that are potentially more effective, but also more uncertain? Researchers have proposed an approach to deal with these dilemmas, and applied it to the case study of an invasive species programme in the US.

Controlled fires could help the regeneration capacity of some insects in regions of intensively managed forests, according to a recent study of Finnish forests that are part of an EU LIFE restoration project. Results indicated that fire can be an effective conservation measure but its impact depends on the region???s history and context.

Combining steam with heat-producing chemicals could control pathogenic viruses in soil, finds new research. The study examined how effective different forms of heat sterilisation of soil were at inactivating three plant viruses. While steam alone was enough to eradicate two of the viruses, the highly resilient tobacco mosaic virus required the addition of exothermic chemicals to reduce it by 97%.