President Trump and the U.S. Department of Education are wrong to target the valuable toolkit, argue David E. DeMatthews and Terri N. Watson.

China’s Zhurong rover has discovered formations on Mars that could signal the remnants of a once vast ocean. Landing in the Utopia Planitia region, the rover identified formations commonly linked to past water presence, supporting the theory that Mars was once home to a massive body of water. While the findings do not offer definitive proof, they bring scientists closer to understanding Mars' history and its potential to support life.

With its particles in two places at once, quantum theory strains our common sense notions of how the universe should work. But one group of physicists says we can get reality back if we just redefine its foundations

Nobel prizewinning theoretical physicist Peter Higgs has died aged 94. He proposed the particle that gives other particles mass – now named the Higgs boson and discovered by the Large Hadron Collider at CERN in 2012

Experiments show that effect doesn’t always follow cause in the weird world of subatomic particles, offering fresh clues about the quantum origins of space-time

In the quantum realm, a particle’s properties can be separate from the particle itself, including its angular momentum – which could require a rethinking of fundamental laws

With its particles in two places at once, quantum theory strains our common sense notions of how the universe should work. But one group of physicists says we can get reality back if we just redefine its foundations

A mathematical study finds that three definitions of what it means for entropy to increase, which have previously been considered equivalent, can produce different results in the quantum realm

We are living in a vaccine-hesitant moment, with conspiracy theories thriving on social media. We need to push back, says Simon Williams

Title: Tools Test Debunks 'Dumb Neanderthals' Theory
Category: Health News
Created: 8/27/2008 2:00:00 AM
Last Editorial Review: 8/27/2008 12:00:00 AM

Title: Study Casts Doubt on 'Chemical Imbalance' Theory of Depression
Category: Health News
Created: 8/9/2022 12:00:00 AM
Last Editorial Review: 8/9/2022 12:00:00 AM

High-throughput sequencing (HTS) technologies have been instrumental in investigating biological questions at the bulk and single-cell levels. Comparative analysis of two HTS data sets often relies on testing the statistical significance for the difference of two negative binomial distributions (DOTNB). Although negative binomial distributions are well studied, the theoretical results for DOTNB remain largely unexplored. Here, we derive basic analytical results for DOTNB and examine its asymptotic properties. As a state-of-the-art application of DOTNB, we introduce DEGage, a computational method for detecting differentially expressed genes (DEGs) in scRNA-seq data. DEGage calculates the mean of the sample-wise differences of gene expression levels as the test statistic and determines significant differential expression by computing the P-value with DOTNB. Extensive validation using simulated and real scRNA-seq data sets demonstrates that DEGage outperforms five popular DEG analysis tools: DEGseq2, DEsingle, edgeR, Monocle3, and scDD. DEGage is robust against high dropout levels and exhibits superior sensitivity when applied to balanced and imbalanced data sets, even with small sample sizes. We utilize DEGage to analyze prostate cancer scRNA-seq data sets and identify marker genes for 17 cell types. Furthermore, we apply DEGage to scRNA-seq data sets of mouse neurons with and without fear memory and reveal eight potential memory-related genes overlooked in previous analyses. The theoretical results and supporting software for DOTNB can be widely applied to comparative analyses of dispersed count data in HTS and broad research questions.

The standard model predicted that the NASA/ESA/CSA James Webb Space Telescope would see dim signals from small, primitive galaxies.

The post New Research Questions Standard Theory of How Galaxies Formed in Early Universe appeared first on Sci.News: Breaking Science News.

We are living in a vaccine-hesitant moment, with conspiracy theories thriving on social media. We need to push back, says Simon Williams

In the first quarter of Monday's Dolphins-Rams game, ESPN reported that Tyreek Hill said a torn ligament in his wrist became worst after he was detained by police.

Two congruent angles are simply pairs of angles with equal measures. You can find congruent angles examples in hundreds of everyday objects.

Peytant has announced that the U.S. Food and Drug Administration (FDA) granted marketing authorisation (clearance to market in the United States as a Class II device) for the AMStent Tracheobronchial Covered Stent System, a therapy platform.

A silly speculation: what if you die, go to heaven, and discover that a god had a set of fundamental rules that it didn’t tell anyone about? I was initially sympathetic to the idea that a god would judge you for doing harm to small helpless creatures — I avoid killing insects without cause — […]

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