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The Short Rate Disconnect in a Monetary Economy [electronic journal].

National Bureau of Economic Research




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The Response to Dynamic Incentives in Insurance Contracts with a Deductible: Evidence from a Differences-in-Regression-Discontinuities Design [electronic journal].




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Price Discrimination in the Information Age: Prices, Poaching, and Privacy with Personalized Targeted Discounts [electronic journal].




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Price-cost tests and loyalty discounts [electronic journal].




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Model-Free International Stochastic Discount Factors [electronic journal].




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Incentives to Discover Talent [electronic journal].




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Historical Econometrics: Instrumental Variables and Regression Discontinuity Designs [electronic journal].




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The geography of EU discontent [electronic journal].




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Gender diversity in corporate boards: Evidence from quota-implied discontinuities [electronic journal].




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Do Lower Minimum Wages for Young Workers Raise their Employment? Evidence from a Danish Discontinuity [electronic journal].




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Discounting the Future: on Climate Change, Ambiguity Aversion and Epstein-Zin Preferences [electronic journal].




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Discovery of excellent ultraviolet nonlinear optical materials in chlorates and bromates with highly stereochemically active lone pairs

Inorg. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QI00462K, Research Article
Chun-Li Hu, Qian-Qian Chen, Fang Kong, Jiang-Gao Mao
The long-neglected stereochemically active lone pair groups ClO3 and BrO3 are demonstrated to be important UV NLO functional motifs based on the fact that AClO3 and ABrO3 possess high SHG effects and short λPM and are promising UV NLO materials.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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‘India is a great discovery’

Acclaimed violinist Elmira Darvarova cherishes her visits to India and speaks of her encounters with Indian classical music.




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A metabologenomics strategy for rapid discovery of polyketides derived from modular polyketide synthases

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04174G, Edge Article
Open Access
Run-Zhou Liu, Zhihan Zhang, Min Li, Lihan Zhang
A metabologenomics workflow using mass defect filtering (MDF) and bioinformatics-based structural prediction was established for rapid screening of modular polyketide natural products, and led to the identification of 22 polyketides.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of penicillic acid as a chemical probe against tau aggregation in Alzheimer’s Disease

Chem. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4SC05469E, Edge Article
Open Access
Jennifer Shyong, Jinliang Wang, Tran Quoc Dung Huynh, Marina Fayzullina, Bo Yuan, Ching-Kuo Lee, Thomas Minehan, Paul M. Seidler, Clay Wang
Alzheimer’s Disease (AD) is a neurodegenerative disorder proven to be caused by the aggregation of protein tau into fibrils, resulting in neuronal death. The irreparable neuronal damage leads to irreversible...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Rediscovering repositories of heritage

Often considered dull and uninviting, Indian museums are storehouses of history and culture, and deserve repeat visits saysShailaja Tripathi




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2024 Land Rover Discovery Sport launched




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Land Rover Discovery Sport: New Discoveries

As a do-it-all SUV, the Land Rover Discovery Sport offers more than its entry-level positioning might suggest




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Meghalaya: A disconcerting disconnect




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The role of silicon in drug discovery: a review

RSC Med. Chem., 2024, 15,3286-3344
DOI: 10.1039/D4MD00169A, Review Article
Open Access
Jenny-Lee Panayides, Darren Lyall Riley, Felix Hasenmaile, Willem A. L. van Otterlo
This review aims to highlight the role of silicon in drug discovery.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of highly potent SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides

RSC Med. Chem., 2024, 15,3469-3476
DOI: 10.1039/D4MD00422A, Research Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Hugo Kocek, Dominika Chalupská, Milan Dejmek, Alexandra Dvořáková, Michala Zgarbová, Michal Šála, Karel Chalupský, Petra Krafčíková, Tomáš Otava, Matúš Drexler, Eliška Procházková, Blanka Klepetářová, Milan Štefek, Ján Kozic, Helena Mertlíková-Kaiserová, Evzen Boura, Jan Weber, Radim Nencka
SARS-CoV-2 nsp14 methyltransferase inhibitors based on adenosine 5'-carboxamides.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery and optimisation of pyrazolo[1,5-a]pyrimidines as aryl hydrocarbon receptor antagonists

RSC Med. Chem., 2024, 15,3477-3484
DOI: 10.1039/D4MD00266K, Research Article
Raitis Bobrovs, Svetlana Terentjeva, Ninni Elise Olafsen, Zilvinas Dambrauskas, Antanas Gulbinas, Toivo Maimets, Indrek Teino, Aigars Jirgensons, Jason Matthews, Kristaps Jaudzems
The aryl hydrocarbon receptor (AHR) is a versatile ligand-dependent transcription factor involved in diverse biological processes, from metabolic adaptations to immune system regulation.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Medicinal chemistry-based perspective on thiophene and its derivatives: Exploring the structural insights to discover plausible druggable leads

RSC Med. Chem., 2024, Accepted Manuscript
DOI: 10.1039/D4MD00450G, Review Article
Shikha Thakur, Devendra Kumar, shivani jaiswal, Kapil Kumar Goel, Pramod Rawat, Vivek Srivastava, Sonia Dhiman, Hemant R Jadhav, Ashish Ranjan Dwivedi
Thiophene is a privileged pharmacophore in medicinal chemistry owing to its diversified biological attributes. The thiophene moiety has been ranked 4th in US FDA drug approval of small drug molecules,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 Mpro inhibitors with improved metabolic stability

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00555D, Research Article
Shenghua Gao, Letian Song, Bing Ye, Mianling Yang, Junyi Li, Manyu Gu, Ann E. Tollefson, Karoly Toth, Peng Zhan, Xinyong Liu
The continuous mutational nature of SARS-CoV-2 and its inter-species' similarities emphasize the urgent need to design and develop more direct-acting antiviral agents against highly infectious variants.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of N-substituted-2-oxoindolin benzoylhydrazines as c-MET/SMO modulators in EGFRi-resistant non-small cell lung cancer

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00553H, Research Article
Stefano Tomassi, Benito Natale, Michele Roggia, Luisa Amato, Caterina De Rosa, Carminia Maria Della Corte, Emma Baglini, Giorgio Amendola, Anna Messere, Salvatore Di Maro, Elisabetta Barresi, Federico Da Settimo, Maria Letizia Trincavelli, Fortunato Ciardiello, Sabrina Taliani, Floriana Morgillo, Sandro Cosconati
Non-small cell lung cancer (NSCLC), the leading cause of cancer-related mortality worldwide, poses a formidable challenge due to its heterogeneity and the emergence of resistance to targeted therapies.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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Campaign to discourage open burning from Nov 6, 588 teams to be deployed: Delhi Minister Rai

Mr. Rai said 588 teams from different civic agencies, including the Municipal Corporation of Delhi (MCD), will be deployed to report open burning incidents across the national capital




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Data and its discontents

The quality of the statistics of a country is a measure of its goodness, say the authors




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Hyundai Motor India debuts at BSE at a discount of 1.48%, falls nearly 6% post listing

This is the biggest ever IPO to have ever hit in the Indian capital markets




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Discover the punch in power yoga

We tried out Power Yoga and found there are many incorrect assumptions the mind makes about the body




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Ageing Kohli, Rohit must rekindle youthful mindset to rediscover lost glory: Greg Chappell

According to Chappell, the ageing Sharma and Kohli must summon the same drive and focus that once marked their prime years if India hopes to reclaim its form on foreign soil




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A journey of discovery

How you can make the best use of a management education.




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Discover your true calling through psychometric tests

It is a useful tool that offers career clarity and opens up new possibilities.




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Discover your true calling

Psychometric test is a useful tool that offers career clarity and opens up new possibilities.




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Computational discovery of two-dimensional tetragonal group IV–V monolayers

RSC Adv., 2024, 14,36173-36180
DOI: 10.1039/D4RA06623E, Paper
Open Access
Qiubao Lin, Jungang Huang, Yimei Fang, Feng Zheng, Kaixuan Chen, Shunqing Wu, Zi-Zhong Zhu
Structural prediction of a stable tetragonal Td4 phase of 2D group IV–V monolayers.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Scientists discover new antidote to cobra venom

A commonly used blood thinner can be repurposed as an inexpensive antivenom treatment, a study published in Science Translational Medicine has said




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Data-driven discovery of electrode materials for protonic ceramic cells

Energy Environ. Sci., 2024, Advance Article
DOI: 10.1039/D4EE03762F, Paper
Open Access
Xueyu Hu, Yucun Zhou, Zheyu Luo, Haoyu Li, Nai Shi, Zhijun Liu, Weilin Zhang, Weining Wang, Yong Ding, Meilin Liu
A schematic representation of a four-stage data-driven material screening methodology, progressing from uncovering unexplored chemical spaces through high-throughput calculations to validating findings in protonic ceramic cells.
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The content of this RSS Feed (c) The Royal Society of Chemistry




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XRDMatch: a semi-supervised learning framework to efficiently discover room temperature lithium superionic conductors

Energy Environ. Sci., 2024, Advance Article
DOI: 10.1039/D4EE02970D, Paper
Zheng Wan, Zhenying Chen, Hao Chen, Yizhi Jiang, Jinhuan Zhang, Yidong Wang, Jindong Wang, Hao Sun, Zhongjie Zhu, Jinhui Zhu, Linyi Yang, Wei Ye, Shikun Zhang, Xing Xie, Yue Zhang, Xiaodong Zhuang, Xiao He, Jinrong Yang
We propose XRDMatch, a semi-supervised learning framework that integrates consistency regularization and pseudo-labeling. Using X-ray diffraction patterns as descriptors, it effectively addresses data scarcity by leveraging abundant unlabeled data.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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How discoms have spurred renewables

Long term power purchase agreements have de-risked investments by private developers in renewables. But discoms need to invest in storage now




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Delhi BJP leaders meet L-G, seek probe into ‘graft’ by discoms




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New genus of jumping spiders ‘Tenkana’ discovered in south India

Unlike related species that live in forests, Tenkana spiders prefer drier areas and ground habitats and have been found in Tamil Nadu, Puducherry, Karnataka, Telangana and Andhra Pradesh 




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Water On The Moon: Surprising New Discovery Reveals The Moon Has More Water Than Expected!

New research reveals that the Moon contains far more water than previously thought, surprising scientists and reshaping future lunar exploration plans!




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Discover your calling

Uncertain about your career options? Low on self-confidence? This career counselling column may help




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'I was trying to discover myself'

'In 2009, I was trying to discover myself as an actor, and that's when the journey started. I'm 41 years old and have been associated with this film for 16 years.'




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An overseas St. Andrews University Student of the 1950s discovers my Scotland.

[Australia] : Published by tckbrown@netspace.net.au, 2015.




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The nature and evidences of saving faith: : in four discourses. / by Samuel Pike, author of Cases of conscience..

Edinburgh : Printed and sold by D. Schaw & Co. Riddell's Close., 1799.




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Rare discount on iPhone 15 in China as competition intensifies

The price of some iPhones has been cut by 5 per cent in a Lunar New Year promotion that will last from January 18-January 21




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Genentech and Lodo team to discover natural products




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Celsius Therapeutics launches to tap single-cell genomics for drug discovery




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Discovery of new poppy enzyme might help improve yeast-based opiate synthesis

Adding enzyme to engineered yeast boosts production of thebaine, a key morphine intermediate




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Verge Genomics raises $32 million for machine learning-backed neuroscience drug discovery