A Mississauga couple is in the midst of a war of words with their townhouse complex's board of directors — which a handful of residents say is imposing unnecessarily strict new rules on the complex's roughly 140 homeowners.

Striking Brampton city workers paused their picket lines on Monday to show respect for war veterans and that means public transit buses in the city ran on their usual schedules without disruption.

One person is dead after a motorcycle and an SUV collided in Mount Albert, Ont., on Monday, Ontario Provincial Police say.

The number of visits to food banks in Toronto hit a new record once again, marking a continuation of a drastic rise in food bank use since the pandemic as Torontonians struggle keeping up with the rising cost of living.

The Ontario Liberal Party is pledging to reduce the income tax rate for middle class families and eliminate provincial sales tax on hydro bills, if they win in the 2026 election.

Statistics Canada data reviewed by CBC Toronto shows a dramatic shift in criminal outcomes in Ontario over the last decade. The majority of criminal cases in the province have ended with charges being withdrawn, stayed, dismissed or discharged before a decision at trial since 2020.

Taylor Swift's Eras Tour, which began March 17, 2023, arrives in Toronto for six shows beginning Thursday and will end in early December after three Vancouver performances. With opening night upon us, here's a look at all the hoopla in Toronto.

The Toronto Police Services Board unanimously approved a new five-year hiring plan for the force on Tuesday.

Macroeconomic risks for grains and oilseeds include China's growth and FX rates.

The high cost of pet care can be an unfair burden to place on your family when you’re gone. Experts say you should set aside cash pet care expenses, and make sure you have a trusted beneficiary in your will.

At 101-years-old, Chase is one of a dwindling number of living veterans in the city who served in the second world war as a member of the Royal Canadian Air Force. 

A new course offered to nursing students at the University of Calgary is shining a light on the impacts of colonization on the health experiences of Indigenous peoples.

Some Ukrainians living in Calgary say they're even more worried for their friends and family back home in light of Donald Trump's election win.

Calgarians who contributed to peacekeeping missions around the world reflected on the country's contributions to this work, highlighting the country's mission in Cyprus, which started 60 years ago.

The provincial government is seeking contractors to restore hundreds of kilometres of land where fireguards were created during the 2023 wildfire season.

The Calgary-based team beat Hamilton Forge FC in a 2-1 nail-biter at home on Saturday, in front of a sold-out crowd of over 7,000 fans at Spruce Meadows.

After curling together for so many years and heading back to yet another Olympics, Jennifer Jones, Kaitlyn Lawes, Jocelyn Peterman and Dawn McEwen are much more than teammates. They're family.

After COVID-19 challenges forced the cancellation of Canada's mixed doubles trials, several top curlers are anxiously waiting to learn whether they will be chosen to represent the country in the discipline at the Beijing Games.

The cancellation of the mixed doubles curling trials has generated a wide variety of emotions among players — illuminating a handful of issues, particularly about scheduling and the selection process as a whole.

Kamloops, B.C., has been selected as the host city of the 2023 Scotties Tournament of Hearts.

It's not a complete surprise that curling and other sports have been cancelled because of the COVID-19 pandemic, but it doesn't make it any easier on teams that had their hopes of representing Northern Ontario at a national curling level dashed.

The OCA's decision Friday to announce that Rachel Homan's team would only represent the province at the national championship if the skip wasn't picked for the Olympic mixed doubles team generated criticism from some corners and confusion from others.

It’s official — Team Galusha will be representing the N.W.T. at the 2022 Scotties Tournament of Hearts in Thunder Bay later this month.

The oft-discussed wild-card setup at the national championships took centre stage again Monday with the release of updated rankings that appeared to determine the play-in game matchup at the Scotties Tournament of Hearts.

Rachel Homan and John Morris join That Curling Show fresh off the news they have been chosen to represent Canada in mixed doubles curling at the Beijing Olympics.

Rachel Homan and John Morris weren't the only ones celebrating after their selection to wear the Maple Leaf in mixed doubles curling competition at the Beijing Olympics. The nomination also cleared the path for Team Hollie Duncan to represent Ontario at the national championship.

Newly announced mixed doubles duo Rachel Homan and John Morris, skips Jennifer Jones and Brad Gushue, and broadcasters Mike Harris, Joanne Courtney and Bruce Rainnie all break down a busy week in curling news.

Curling Canada says the Scotties Tournament of Hearts in Thunder Bay, Ont., will operate under Ontario's current public health measures and an approved framework from the office of the chief medical officer.

CME Group, the world's leading derivatives marketplace, today announced its new CBL Australian Carbon Credit Unit (ACCU) futures have launched and are available for trading. A total of five...

Record revenue of $1.6 billion Record quarterly ADV of 28.3 million contracts - the second consecutive quarter of volume, open interest growth across every asset class CHICAGO, Oct. 23, 2024...

CME Group, the world's leading derivatives marketplace, today announced its new Spodumene CIF China (Fastmarkets) futures have launched and are available for trading. A total of 29 contracts...

CME Group, the world's leading derivatives marketplace, today announced it has received approval from the National Futures Association (NFA) to establish a futures commission merchant (FCM). "We...

CME Group, the world's leading derivatives marketplace, today announced that open interest in its global benchmark Henry Hub futures contract reached a record 1.73 million contracts on October 30,...

Record October ADV for interest rate, energy, metals and agricultural products Record October ADV across U.S. Treasury and SOFR complexes All-time record monthly ADV in U.S. Treasury options and...

Farmer sentiment saw an unexpected surge in October ahead of the upcoming U.S. election, according to the latest Purdue University/CME Group Ag Economy Barometer. The index rose to 115, marking a...

Indiana University took first place, with the rest of the top five from outside the United States Record participation from nearly 570 teams across 24 countries CHICAGO, Nov. 7, 2024 /PRNewswire/...

Chief Financial Officer Lynne Fitzpatrick Appointed to President and CFO Chief Operating Officer Julie Holzrichter to Step Down and Assume Advisory Role Suzanne Sprague to Succeed Holzrichter CHICAGO,

A researcher may have many reasons for wanting to establish new laboratory colonies from field-collected mosquitoes. In particular, the ability to study the diversity found within and among natural populations in a controlled laboratory environment opens up a wide range of possibilities for understanding how and why burdens of vector-borne disease vary over space and time. However, field-collected mosquitoes are often more difficult to work with than established laboratory strains, and considerable logistical challenges are involved in safely transporting field-collected mosquitoes into the laboratory. Here, we provide advice for researchers working with Aedes aegypti, Anopheles gambiae, and Culex pipiens, as well as notes on other closely related species. We provide guidance on each stage of the life cycle and highlight the life stages for which it is easiest to initiate new laboratory colonies for each species. In accompanying protocols, we provide methods detailing Ae. aegypti egg collection and hatching as well as how to transport larvae and pupae from the field.

The establishment of neural connectivity is a major part of neural development. The central nervous system (CNS) midline is the most characterized axon guidance choice point, and work in Drosophila has played a pivotal role in understanding the molecular mechanisms responsible. Axons respond to attractive cues such as Netrin via the Frazzled receptor, and repulsive cues such as Slit via Robo receptors. Both signals are expressed at the CNS midline, affect pioneer axons, and have dramatic effects on the axon scaffold as a whole. Here, we focus on previous research analyzing classic mutants in the Slit/Robo pathway, which can readily be detected with a dissecting microscope. We also discuss analyzing these mutants in a teaching lab situation. The combination of sophisticated genetics and reliable axonal markers in Drosophila allows phenotypic analysis to be performed at the single-cell level. The elaborate architecture of neurons is very sensitive to disruption by genetic mutations, allowing the effects of novel mutations to be easily detected and assessed.

CRISPR–Cas9 has revolutionized gene editing for traditional and nontraditional model organisms alike. This tool has opened the door to new mechanistic studies of basic mosquito biology as well as the development of novel vector control strategies based on CRISPR–Cas9, including gene drives that spread genetic elements in the population. Although the promise of the specificity, flexibility, and ease of deployment CRISPR is real, its implementation still requires empirical optimization for each new species of interest, as well as to each genomic target within a given species. Here, we provide an overview of designing and testing single-guide RNAs for the use of CRISPR-based gene editing tools.

Anautogenous female mosquitoes, which ingest a blood meal from warm-blooded vertebrates to produce eggs, have become a valuable model organism for investigating signaling pathways and physiological processes that occur during egg development. Different molecular pathways tightly regulate the initiation of egg development and are governed by a balance among different insect hormones. Gravid (mature egg-carrying) females deposit fully developed eggs at the end of each gonotrophic cycle, which is defined as the time interval between the ingestion of a blood meal to oviposition. An intact eggshell protects the oocyte and embryo inside from external factors such as desiccation, physical damage, etc., and the various eggshell proteins are spatially and temporary deposited during oogenesis. Additionally, follicle resorption (oosorption) during blood meal–induced mosquito ovarian follicle development is an adapted physiological process that optimizes reproductive fitness. Mosquito oocytes grow and mature synchronously throughout oogenesis; however, during the later stages of oogenesis, some oocytes may undergo oosorption if sufficient nutrients are unavailable. This introduction highlights how mosquito egg development can be used to investigate follicular resorption and identify proteins involved in eggshell formation in Aedes aegypti mosquitoes.

Volker (OM Montenegro) describes how their outdoor lessons for Roma kids were threatened by bad weather. Then God provided not only the solution - building a carport as a shelter - but also the funds and manpower needed to build it.

Anna (Germany) and Christina (Canada) are the youngest members of OM Montenegro. They describe how God called them into missions, and led them unexpectedly to Montenegro, a Balkan country neither had heard much about before. Here God is changing them as they prepare for further service...

At 33, Igor, from Serbia, was sick, jobless and homeless. But one winter night he met Jesus. Now he serves God with OM in Montenegro.

Four OM guys in Bar, Montenegro, and four guys from a nearby Roma camp take a hiking/camping trip together.

No public playground exists in Bar, Montenegro. This year, OM Montenegro plans to build one with the help of an outreach team.

Four volunteers from Switzerland. One empty park. Ten days to build a playground. Could it be done?

Social workers in Bar, Montenegro, introduce OM workers to “hidden” people, enabling them to give holistic help, which the social workers alone could not provide.

OM worker Jelena desires to help the broken hearted and see local believers grow. Read what God has done in her life.