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Coaches, Athletic Director Facing Charges Following Alleged Hazing Incident

Two high school basketball coaches and an assistant principal/athletic director are facing criminal charges stemming from an alleged hazing incident that resulted in the hospitalization of a 15-year-old boy.




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Irish amateurs hold off Russia's South Region to win

Eoin Hayes's first-half strike earned the Group B points for Irish side Region 2 as Russia's South Region failed to convert their possession into a single shot on goal.




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Region 2 reach final with Olomouc win

Eoin Hayes struck either side of half-time as Region 2 accelerated away from Olomouc, a 4-1 victory enough to take them into Sunday's UEFA Regions' Cup final as Group B winners.




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Zagreb back in final after Ingulec win

Losing finalists in 2015, Zagreb have booked their place in Sunday's UEFA Regions' Cup decider, captain Željko Štulec marshalling them to a convincing Group A victory.




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Dolny Śląsk win Regions' Cup final: as it happened

Poland's Dolny Śląsk came from behind to beat hosts Bavaria 3-2 for the amateur title in a final of five penalties.




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Dolny Śląsk win 2019 Regions' Cup: at a glance .

Dolny Śląsk beat hosts Bavaria 3-2 in a thrilling final to become only the second two-time winners.




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Allowing people to be who and what they are, without fear of prejudice, is the hallmark of a civilised society

If you have never given your gender much thought, count yourself lucky. If that tick in the box on almost every form requires no more effort than a flick of the wrist, be aware that for many people gender is not so straightforward.




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Films Of The Week: Barry Jenkins's Oscar winner Moonlight and Greta Gerwig's adaptation of Little Women

Moonlight, Film 4, Wednesday, 9pm




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The Baffling Specter of Windows 7

Why hasn't every PC user on the planet upgraded to Windows 10 by now? Because Microsoft, as usual, can't communicate to anyone why they should.




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A Classroom Strategy: Drawing Arguments From Evidence (Video)

William Leou, a 6th grade science teacher at the Brooklyn School for Collaborative Studies, uses an organizational worksheet to help students draw arguments from evidence.




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Where They Are: The Nation's Small But Growing Population of Black English-Learners

In five northern U.S. states, black students comprise more than a fifth of ELL enrollment.




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Gap Growing in Teacher-Turnover Rates: Research

Teachers coming from alternative programs leave the profession at higher rates than their traditionally certified peers, and that gap is growing, a study finds.




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Brief Motivational Interviewing Intervention for Peer Violence and Alcohol Use in Teens: One-Year Follow-up

Youth violence and alcohol misuse are a preventable public health problem. Previous studies have demonstrated the efficacy of brief interventions in the emergency department (ED) in reducing alcohol misuse and related consequences among older adolescents and adults.

This study supports the efficacy of brief interventions in the ED in reducing peer aggression and victimization 12 months after ED visit. The previous reductions in alcohol consequences noted at 6 months follow-up were not sustained at 12 months. (Read the full article)




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Cobedding and Recovery Time After Heel Lance in Preterm Twins: Results of a Randomized Trial

Skin-to-skin contact with mothers and fathers has been associated with lower pain reactivity and enhanced physiologic recovery after heel lance. The effect of skin-to-skin contact between preterm twins during cobedding on pain response has yet to be studied.

We demonstrate that cobedding significantly diminished time to recovery in preterm twins after heel lance but did not lower pain reactivity. (Read the full article)




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Allowing Adolescents and Young Adults to Plan Their End-of-Life Care

Discussing end-of-life (EoL) care with adolescents and young adults (AYAs) is difficult. Often, such conversations are delayed or avoided, but AYAs contemplate EoL issues and want to make decisions about their care. Few established resources exist to help this process.

Results support the use of a developmentally appropriate document that allows AYAs an opportunity to share their choices about EoL care and how they would like to be remembered in the future. (Read the full article)




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Childhood and Adolescent Television Viewing and Antisocial Behavior in Early Adulthood

Many studies have identified an association between television viewing and antisocial behavior, although very few have been able to demonstrate a cause-and-effect sequence. The issue of whether excessive television viewing contributes to antisocial behavior remains controversial.

Excessive television viewing during childhood and adolescence was associated with objective and subjective measures of antisocial behavior in adulthood. These associations were not explained by preexisting antisocial tendencies or other potential confounders. Excessive television appears to have long-term psychosocial consequences. (Read the full article)




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Waning Immunity to Pertussis Following 5 Doses of DTaP

Despite high coverage with acellular pertussis vaccine (DTaP), rates of pertussis have increased substantially in 7- to 10-year-olds in recent years. Duration of protection with 5 doses of DTaP may wane earlier than expected and is currently not well described.

This evaluation reports increasing risk of pertussis in the 6 years after receipt of the fifth DTaP dose, suggesting that waning of vaccine-induced immunity is occurring before the recommended adolescent booster dose at 11 to 12 years of age. (Read the full article)




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The Relationship Between Parents' and Children's Television Viewing

Many children exceed the American Academy of Pediatrics' recommendation to limit non-educational screen media to < 2 hours per day. The household media environment shapes children's television viewing (TVV), and heavy screen time is associated with poor health outcomes.

Parent TVV is a stronger predictor of child TVV than traditional media "access" and "rules" variables regardless of child age. This research highlights an important factor of child TVV that has been underemphasized in most studies and outreach efforts. (Read the full article)




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Pediatrician-led Motivational Interviewing to Treat Overweight Children: An RCT

Obesity and overweight can seriously affect health outcomes. Many obesity prevention interventions have been proposed, but few have been effective. Motivational interviewing in primary care seems promising, but results in BMI control are controversial and require further investigation.

This is the first study to demonstrate the effectiveness of pediatrician-led motivational interviewing for BMI control in overweight children aged 4 to 7 years. Nevertheless, no effect was observed in boys or when the mother’s education level was low. (Read the full article)




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Television Viewing, Bedroom Television, and Sleep Duration From Infancy to Mid-Childhood

Inadequate sleep in childhood is associated with poor mental and physical health. Numerous cross-sectional studies reveal associations between television viewing and the presence of a bedroom TV and inadequate sleep in older children and adolescents, but longitudinal research is limited.

More TV viewing, and, among racial/ethnic minority children, bedroom TV, were associated with shorter sleep from infancy to midchildhood. These results raise the possibility that interventions to reduce TV could improve children’s sleep. (Read the full article)




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Neonatal Outcome Following Cord Clamping After Onset of Spontaneous Respiration

Delaying cord clamping beyond 30 to 60 seconds after birth seems beneficial for all infants due to blood transfusion from placenta. Experimental data have demonstrated that ventilation implemented before cord clamping improved cardiovascular stability by increasing pulmonary blood flow.

Healthy self-breathing neonates in a low-resource setting are more likely to die if cord clamping occurs before or immediately after onset of spontaneous respirations. The risk of death/admission decreases by 20% for every 10-second delay in clamping after breathing. (Read the full article)




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Behavioral Health Services Following Implementation of Screening in Massachusetts Medicaid Children

Behavioral health (BH) screening is known to increase identification of children with BH issues, but in small-scale studies, rates of follow-up after screening have been reported to be low.

This study examines the relationship between BH screening and the receipt of BH services in Massachusetts Medicaid children. Nearly 60% of children identified with BH problems received BH services, but only 30% of newly identified children received BH services. (Read the full article)




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Differential Maternal Feeding Practices, Eating Self-Regulation, and Adiposity in Young Twins

Restrictive feeding by parents is associated with poorer eating self-regulation and increased child weight status. However, this association could be due to confounding home environmental or genetic factors that are challenging to control.

Differential maternal restrictive feeding is associated with differences in twins' caloric compensation and BMI z score. Controlling for the shared home environment and partially for genetics, these findings further support a true (ie, unconfounded) association between restriction and childhood obesity. (Read the full article)




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Postnatal Growth Following Prenatal Lead Exposure and Calcium Intake

Lead is an ubiquitous environmental pollutant, and no safe threshold for blood lead level in children has been discovered yet. Prenatal lead exposure affects growth of children.

Low level of prenatal lead exposure of <5.0 μg/dL affects postnatal children’s growth, which was further intensified by low calcium intake. (Read the full article)




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Motivational Interviewing With Parents for Obesity: An RCT

Motivational interviewing (MI) has been found to increase the effectiveness of weight loss programs in obese children and adolescents. Although parental involvement seems to be linked to its effectiveness, strong conclusions cannot be drawn.

The present study found that MI with parental involvement is an effective strategy in changing obesity-related outcomes and has additional effects beyond MI with adolescents only. These findings are important when administering MI interventions in school settings. (Read the full article)




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Motivational Interviewing and Dietary Counseling for Obesity in Primary Care: An RCT

Childhood obesity rates in the United States remain at historic highs. The pediatric primary care office represents an important, underutilized source of intervention. There is a need to test the efficacy of motivational interviewing for pediatric obesity in primary care.

This is among the first large-scale randomized trials to show significant reductions in BMI and that motivational interviewing, delivered by trained providers in the primary care setting, can be an important and feasible part of addressing childhood obesity. (Read the full article)




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Cognition and Brain Structure Following Early Childhood Surgery With Anesthesia

Permanent neuronal deletion and neurocognitive impairment after anesthetic exposure in animals raised substantial concern that similar effects occur in children. Human studies were equivocal but have not combined structural and intelligence tests in otherwise healthy children after childhood anesthesia.

Anesthetic exposure for surgery did not lead to measurable neuronal elimination in brain regions previously identified in animals. However, language comprehension and performance IQ were decreased in exposed children and associated with decreased gray matter, primarily in posterior brain regions. (Read the full article)




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Mycophenolate Mofetil Following Rituximab in Children With Steroid-Resistant Nephrotic Syndrome

Treatment of idiopathic steroid-resistant nephrotic syndrome is challenging, and therapeutic options are limited. In spite of good initial response with rituximab, responders always remain prone to further relapse, necessitating either repeat course of rituximab or addition of another steroid-sparing immunosuppressant.

Mycophenolate mofetil may be an effective maintenance therapy to consider as an additive immunosuppressant after induction with rituximab in maintaining remission among children with refractory steroid-resistant nephrotic syndrome. (Read the full article)




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Status update on Abington, Brandywine and Great Valley campuses

With Pennsylvania Gov. Tom Wolf’s March 25 “Stay at Home” order, Penn State is updating the status of its Abington, Brandywine and Great Valley campuses.




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Lion Cage pitch competition winner aiming to reduce rotator cuff re-tear rates

Saif Khalil, founder and CEO of Aevumed, won first place at the REV-UP Center for Entrepreneurship's Lion Cage pitch competition. Aevumed develops medical devices designed to help reduce rotator cuff re-tear rates.




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Netherlands win World Cup play-offs

The Netherlands took Europe's last finals berth after seeing off Denmark and Switzerland in the play-offs.




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Bronze, Hegerberg, Henry: who will win?

We know the 2018/19 UEFA Women's Player of the Year will be from Lyon: but which one?




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Straight Up Conversation: First American to Win WISE Prize for Education Innovation

Rick talks with Larry Rosenstock, education icon, the founder and CEO of High Tech High, and recent recipient of the WISE Prize for Education, about what he's learned after a half century in education.




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Grammy-winning, genre-smashing quartet to visit Williamsport

Groundbreaking, Grammy-winning quartet Béla Fleck & The Flecktones is celebrating its 30th anniversary with an extended tour that will stop by the Community Arts Center on Tuesday, March 24, at 7:30 p.m.




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Enter for Your Chance to Win a OnePlus 2

Is $349 still too pricey for a OnePlus 2? Enter our contest and you could get one for free.




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Wing play drill

We present a practice exercise to improve your team's potency in attack from wide positions.




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Burundi after Six Months of Transition: Continuing the War or Winning Peace?




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Transferable Resistance Gene optrA in Enterococcus faecalis from Swine in Brazil [Mechanisms of Resistance]

OptrA is an ATP-binding cassette (ABC)-F protein that confers resistance to oxazolidinones and phenicols, and can be either plasmid or chromosomally encoded. We isolated 13 Enterococcus faecalis strains possessing linezolid MIC ≥ 4 mg/L from nursery pigs in swine herds located across Brazil. Genome sequence comparison showed that these strains possess optrA in different genetic contexts occurring in 5 different E. faecalis sequence type backgrounds. The optrA gene invariably occurred in association with an araC regulator and a gene encoding a hypothetical protein. In some contexts, this genetic island was able to excise and form a covalently closed circle within the cell which appeared to occur in high abundance, and to be transmissible by co-resident plasmids.




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Population pharmacokinetics of piperacillin following continuous infusion in critically ill patients: Impact of renal function on target attainment [Clinical Therapeutics]

Pharmacokinetic changes are often seen in patients with severe infections. Administration by continuous infusion has been suggested to optimize antibiotic exposure and pharmacokinetic/pharmacodynamic (PK/PD) target attainment for β-lactams. In an observational study, unbound piperacillin concentrations (n=196) were assessed in 78 critically ill patients following continuous infusion of piperacillin/tazobactam (ratio 8:1). The initial dose of 8, 12 or 16 g (piperacillin component) was determined by individual creatinine clearance (CRCL). Piperacillin concentrations were compared to the EUCAST clinical breakpoint MIC for Pseudomonas aeruginosa (16 mg/L), and the following PK/PD targets were evaluated: 100% fT>1xMIC and 100% fT>4xMIC. A population pharmacokinetic model was developed using NONMEM 7.4.3 consisting of a one-compartment disposition model with linear elimination separated into non-renal and renal (linearly increasing with patient CRCL) clearances. Target attainment was predicted and visualized for all individuals based on the utilized CRCL dosing algorithm. The target of 100% fT>1xMIC was achieved for all patients based on the administered dose, but few patients achieved the target of 100% fT>4xMIC. Probability of target attainment for a simulated cohort of patients showed, that increasing the daily dose by 4 g increments (piperacillin component) did not result in substantially improved target attainment for the 100% fT>4xMIC target. To conclude, in patients with high CRCL combined with high-MIC bacterial infections, even a CI regimen with a daily dose of 24 g may be insufficient to achieve therapeutic concentrations.




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Bad Flaw in Windows 10 Also Affects Chrome Browser

Security researchers are demonstrating how you can use the Windows 10 flaw, CVE-2020-0601, to spoof the trusted digital certificates for official website domains on Google's Chrome browser. These same certificates can warn you about hacking attempts.




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Tech Company Wins Ed. Dept Award to Create Accessible Books

Benetech, a Palo Alto, Calif. based software company, is embarking on is third 5-year award with the U.S. Department of Education to create books for students with print disabilities.




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Penn State Lehigh Valley announces 2020 student life and athletics award winners

Students celebrated for athletic and student life achievements during the Finally Finished Fest




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Spain win #WU17EURO: at a glance

Spain ended Germany's two-year reign as champions to claim their fourth title.




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Cristiano Ronaldo wins UEFA.com Goal of the Season vote

Cristiano Ronaldo's overhead kick for Real Madrid against his current club Juventus has been voted UEFA.com Goal of the Season.




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Germany win #WU17EURO: at a glance

Germany pipped the Netherlands on penalties to make it seven titles in the 12 #WU17EURO seasons.




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Portugal win Futsal EURO, Ricardinho top scorer: at a glance

Portugal are UEFA Futsal EURO winners for the first time while Ricardinho dominated the individual honours in a record-breaking personal tournament: the full story.




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Fish, wine, and social media: Hazleton virtual research fair winners announced

Wine, fish, and excessive use of social media were a few of the topics that earned students top honors in Penn State Hazleton's first-ever virtual Undergraduate Research Fair.




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How to Tune Up Your Windows 10 PC for Free

It's only a matter of time before your Windows 10 PC begins to run slowly. You can kick the operating system back into high gear with these useful tips. And they won't cost you a penny.




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How to Run Windows 10 From a USB Drive

Loading and running Windows 10 from a USB drive is a handy option when you're using a computer saddled with an older version of Windows.




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How to Search in Windows 10

The Windows 10 search feature seems pretty simple, but it can be even more effective. Here are some ways to control your searches and find things faster.