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Enhancing the Resilience of the Nations Electricity System

With growing risks to the nation’s electrical grid from natural disasters and as a potential target for malicious attacks, the U.S. Department of Energy (DOE) and the U.S. Department of Homeland Security (DHS) should work closely with utility operators and other stakeholders to improve cyber and physical security and resilience, says a new congressionally mandated report by the National Academies of Sciences, Engineering, and Medicine.




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Up to 8 Million Deaths Occur in Low- and Middle-Income Countries Yearly Due to Poor-Quality Health Care, Says New Report

Recent gains against the burden of illness, injury, and disability and commitment to universal health coverage (UHC) are insufficient to close the enormous gaps that remain between what is achievable in human health and where global health stands today, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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U.S. Department of Transportation Should Revisit Federal Safety Regulations for Liquid Petroleum Gas Distribution Systems, Says New Report

Current federal safety regulations for small distribution systems used for propane and other liquefied petroleum gases (LPGs) should be improved for clarity, efficiency, enforceability, and applicability to risk, says a new reportfrom the National Academies of Sciences, Engineering, and Medicine.




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New Investments Are Needed to Sustain NASA’s Instrumentation and Facilities for Future Extraterrestrial Sample Analyses, Says New Report

NASA’s investment in new instruments to analyze extraterrestrial samples is insufficient to provide for replacement of existing instruments, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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Metrics for Successful Supercritical Water Oxidation System Operation at the Blue Grass Plant

The supercritical water oxidation (SCWO) system is a secondary waste processing reactor of the Blue Grass Chemical Agent Destruction Pilot Plant (BGCAPP). It is perhaps second in importance behind the agent neutralization reactors, which perform base hydrolysis of chemical warfare agents stored at the Blue Grass Army Depot.




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Virtual Clinical Trials - A New Model for Patient Engagement

For some patients, the ability to participate in a clinical trial from the comfort of one’s home is becoming a reality.




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National Academies Report Helps Inform Metrics for Healthy People 2030

The National Academies today released Criteria for Selecting the Leading Health Indicators for Healthy People 2030, the first of two reports that will help inform the development of Healthy People 2030 (HP2030).




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Patricia Gabow Receives Lienhard Award From National Academy of Medicine for Transforming Safety Net Hospital Into Nationally Recognized Health System

For her role in transforming a safety net hospital into a national model for high-quality, cost-efficient health care, the National Academy of Medicine today announced Patricia Gabow is the recipient of the 2019 Gustav O. Lienhard Award for Advancement of Health Care.




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Food and Nutrition Board Marks 80 Years of Advising the Nation

Symposium participants examine what climate change, obesity, and personalized medicine mean for nutrition in the future




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Mal/EncPK-NS being distributed from right-wing political site




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Trump Returns To The Road With Arizona Trip To Mask-Maker

President Trump walks to the White House on Sunday, after returning from Camp David in Maryland.; Credit: Andrew Caballero-Reynolds/AFP via Getty Images

Tamara Keith and Don Gonyea | NPR

As President Trump attempts to project an image of America rising out of quarantine and beginning to reopen, he's set to travel to an Arizona factory that's expanded into production of N95 face masks to respond to the coronavirus pandemic.

And while the trip is in part meant to tell a positive story about the Trump administration's response, it also highlights the challenges of the current moment.

Arizona remains under a modified stay-at-home order until May 15, though Republican Gov. Doug Ducey allowed some retail establishments to begin to open voluntarily Monday. The state hasn't yet notched the two consecutive weeks of reduced COVID-19 cases called for as a first step in the White House guidelines for reopening. In fact, the number of confirmed cases in the state is on the rise.

And Trump's trip itself will be anything but normal. Those traveling with the president or coming in close proximity to him in Arizona are being tested for the coronavirus. Social distancing measures are expected.

"The President takes the health and safety of everyone traveling in support of himself and all White House operations very seriously," White House spokesman Judd Deere said in a statement provided to NPR. "When preparing for and carrying out any travel, the White House's operational teams work together to ensure plans to incorporate current CDC guidance and best practices for limiting COVID-19 exposure are followed to the greatest extent possible."

Asked last week if he would wear a mask on the trip, Trump was noncommittal.

"I'm going to have to look at the climate. I'd have no problem wearing a mask. I don't know," Trump said at the White House. "I'm supposed to make a speech. I just don't know: Should I speak in a mask? You're going to have to tell me if that's politically correct. I don't know. If it is, I'll speak in a mask."

Vice President Mike Pence faced criticism for not wearing a mask while visiting the Mayo Clinic in Minnesota last week, in apparent violation of the center's policy. Sitting next to Trump at a televised town hall Sunday night, Pence said he "should have worn a mask at the Mayo Clinic."

Pence has left Washington, D.C., a few times recently — a series of trips the White House used in part as test runs for Trump to get back on the road.

Different than the big rallies

Tuesday's travel is a far cry from Trump's last trip to Arizona, for a campaign rally on Feb. 19. He didn't mention the coronavirus in his speech that night, and when asked about it in an interview with a local TV reporter, he downplayed the risk.

"I think it's going to work out fine," Trump told Fox 10 Phoenix. "I think when we get into April, in the warmer weather, that has a very negative effect on that and that type of a virus. So let's see what happens, but I think it's going to work out fine."

As of Monday morning, more than 350 deaths had been attributed to COVID-19 in Arizona, according to researchers at Johns Hopkins University, with about 68,000 deaths nationwide.

Trump still yearns for those big rallies of the not-so-distant past, musing about the day when he can pack arenas again and not have to have people spaced 6 feet apart. But for now, he's relishing the idea of escaping the confines of the White House. Aside from a trip to the presidential retreat at Camp David last weekend, this will be Trump's first trip away from the White House since March 28, when he sent off the Navy hospital ship USNS Comfort in Norfolk, Va. While it's been a little more than a month, Trump has described himself as stuck at the White House "for many months."

In Phoenix, Trump will tour a Honeywell aerospace manufacturing facility that freed up space to start making N95 respirator masks. According to a company spokesman, the first masks rolled off the line on April 30, ahead of schedule. Once up to full capacity, it will make 10 million of the masks per month. The company said it would be adding 500 employees to make the masks. Another Honeywell factory in Rhode Island also started making masks last month. Most of them are headed to the federal government, which is distributing the protective equipment. Mask shortages have been a major concern for health care workers treating patients with the highly contagious coronavirus.

Battleground state

Although there isn't officially a political component to the trip, Arizona is a state Trump won in 2016, but that Democrats expect to be competitive in 2020.

Trump's visit clearly underscores how he isn't taking anything for granted in the state in 2020. His goal is to remind voters how the Arizona economy was booming before the pandemic.

"Arizona is a state where President Trump's campaign will be aggressive, where we have had a presence since 2015," said Erin Perrine, principal deputy communications director for the reelection campaign. "We will reach voters where ever they are — sharing the message that only President Trump can bring back the booming Trump economy and highlighting his strong leadership during the coronavirus."

For several election cycles, Democrats have been eyeing Arizona as a state they might put in the presidential win column. Analysts say Democrats challenge will will be to win in the suburbs and get a solid turnout from Hispanics, even as the pandemic's effect on campaigning and on the actual process of voting is yet to be known. No Democratic nominee had carried the state since Bill Clinton in 1996. In 2016, there was talk of a late play for the state by Hillary Clinton's campaign, but that was seen more as overconfidence than her actually have a real shot at winning there. Then, when the votes were counted, Trump won the presidency, including a victory in Arizona, but his margin in the state was only 3.5%.

Four years earlier, GOP nominee Mitt Romney carried the state over President Obama by more than 9 percentage points. Democrats took Trump winning so narrowly in the state as a sign that maybe the future was closer than people realized. Longtime GOP strategist Chuck Coughlin says Democrats kept the story line going two years later by winning four statewide offices, including an open U.S. Senate seat and secretary of state. Now strategist Coughlin says, "There is a trend line going on, Republicans have had to acknowledge that, and the swing voters have become more important — independents and Republican suburban women." He says those are the keys to a Democratic victory in the state.

An average of recent polls shows former Vice President Joe Biden, the presumptive Democratic presidential nominee, leading in head-to-head matchups. Although horse race polling this far out, and especially in the middle of an unprecedented crisis, isn't necessarily predictive, it's one of a few causes for alarm for Republicans.

In 2018, Democrat Kyrsten Sinema won an open U.S. Senate seat in Arizona. Another Senate seat is up in 2020, and the latest campaign finance reports show Democratic challenger Mark Kelly with nearly twice as much cash on hand as incumbent Republican Sen. Martha McSally. Kelly has also led in recent polls.

McSally portrays herself as a strong ally of Trump's, even echoing his style of negative campaigning. Here's how she began her remarks when Trump called her up to speak at that big rally in February, "I just want to say I have a message for the liberal hack media in the back," she told the noisy crowd, "Arizona is going to vote in November to keep America great and send President Trump back to the White House.

In April McSally tweeted that she was able to secure ventilators for her state after talking to Trump.

"Huge news for Arizona!" McSally tweeted. "I spoke with @realDonaldTrump on Wednesday afternoon to request additional ventilators from the Strategic National Stockpile. Today, POTUS delivers with 100 ventilators headed to AZ. Thank you to President Trump and @VP for hearing our call."

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Restrict What Personal Data Is Shared on the Facebook API Platform




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Palm Springs Film Festival: Patrick Stewart's comedic talent lights up 'Match'

Actors Carla Gugino, Matthew Lillard and Sir Patrick Stewart pose at the "Match" screening during the Palm Springs International Film Festival on January 3, 2015 in Palm Springs, California. ; Credit: Chelsea Lauren/Getty Images for PSIFF

R.H. Greene

Is there a happier star in Hollywood than Patrick Stewart?

Certainly no one seems to be having more fun than the onetime Star Trek captain and current (and seemingly permanent) X-Man. And why shouldn't Sir Patrick be pleased with himself? He really has got it all: a thriving stage profile in both New York and London, the unconditional love of a vast and loyal fan base, and a film career that oscillates freely between franchise blockbusters and the small, character-driven chamber pieces Stewart so clearly relishes.

"Match" is about as small a movie as Stewart has ever appeared in: a well-intentioned three-character film studded with very funny dialogue courtesy of writer/director Stephen Belber, upon whose play "Match" is based.

Stewart plays an aging gay dance instructor named Tobi Powell, who may or may not have sired a child back in the swinging 60s – an era movies now take to have been 10 years of uninterrupted orgy punctuated by Beatles records and gunshots aimed at the Kennedy brothers.

As the saying goes, "If you can remember the '60s, you weren't there." Stewart's Tobi Powell was vibrantly there at the time, so it's perhaps natural that he can't seem to recall whether or not one of his rare couplings with a female partner might have had some unintended consequences.

Mincing slightly and speaking in an accent that sounds Midwestern by way of Wales, Stewart is an absolute blast to watch. His genuine (and usually underutilized) flair for comedy is roguishly on display, allowing "Match" to shift between pathos and farce with an assurance born more of the performer's bravado than the emotional contours of Belber's somewhat overeager text.

Though allegedly a bit of a shut-in, Tobi is a minor masterpiece of a lost and exuberant art form: the exaggerated star turn. It's unsurprising Frank Langella got a Tony nomination for playing him on Broadway a decade ago, and at least a bit unexpected that Stewart has gone completely unnoticed this awards season, even by the nomination-happy Golden Globes.

Belber's best writing is mostly his comedic stuff. One aria comparing cunnilingus to knitting may just be the best scene of its type since Meg Ryan faked an orgasm in "When Harry Met Sally" a quarter century ago.

Solid and believable supporting turns from Carla Gugino and Matthew Lillard add to the fun until Belber's script bogs down in the third act into the kind of paint-by-numbers epiphany shtick even TV has given up on at this point.

WATCH: The official trailer for "Match," starring Patrick Stewart

Everybody cries. Everybody changes. Everybody yawns.  Or I did anyway.

Still, go see this movie — or better yet, watch it on your phone, since it's shot almost entirely in close up — to see a grand and gracefully aging actor strut his stuff with contagious delight. You will definitely laugh, and, God, does this movie hope you'll also cry.

But if you do weep, don't be surprised if, like Tobi himself, you hate yourself in the morning.

Off-Ramp contributor R. H. Greene is covering the 26th Annual Palm Springs International Film Festival, where he recently saw the new comedy "Match" starring Patrick Stewart. "Match" comes to theaters and video-on-demand on Jan. 14.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Triple Play: What An Abbreviated 2020 MLB Season Might Look Like

People sit on a hill overlooking Dodger Stadium on what was supposed to be Major League Baseball's opening day, now postponed due to the coronavirus, on March 26, 2020 in Los Angeles, California. ; Credit: Mario Tama/Getty Images

AirTalk®

Had the 2020 MLB season started at the end of March like it was scheduled to, at this point we’d be starting to see divisions shape up, star pitchers and position players separating themselves from the rest of the league and a first look at who this year’s contenders and pretenders really would be. Sadly, the COVID-19 outbreak forced the league to postpone the start of the season, and now the question has become if there will be a season, not when. 

Not to be dragged down by the idea of no baseball, Wall Street Journal sports writer Jared Diamond took a recent proposal the league floated for an abbreviated 2020 campaign and gamed out how that might look in real life. The league’s idea would do away with the National and American Leagues and divide all 30 MLB teams into three divisions of 10 teams separated by region, and those teams would play in empty stadiums and only against other teams in their geographic division in the interests of reducing travel. But how viable is this, really? And what other considerations would the league and players union have to take with regards to testing and protocol for what happens if someone were to contract COVID-19? Is there a world where baseball still happens this year?

Today on AirTalk, Jared Diamond joins the Triple Play of Larry Mantle, Nick Roman and A Martinez to talk about what a shortened 2020 MLB season might look like, which teams stand to win and lose the most from the realignment and what other precautions the league would have to take against the spread of COVID-19.

Guests:

Jared Diamond, national baseball writer for the Wall Street Journal; his new book is "Swing Kings: The Inside Story of Baseball's Home Run Revolution” (William Morrow, March 2020); he tweets @jareddiamond

Nick Roman, host of KPCC’s “All Things Considered”; he tweets @RomanOnTheRadio

A. Martinez, host of KPCC’s “Take Two”; he tweets @amartinezLA

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Need to strip HDCP from a USB 3.0 cable - any solutions?




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Supreme Court Guarantees Right To Unanimous Verdict In Serious Criminal Trials

; Credit: J. Scott Applewhite/AP

Nina Totenberg | NPR

What does the right to a unanimous jury verdict have to do with abortion, or school prayer, or federal environmental regulations? Stay tuned.

The U.S. Supreme Court Monday struck down state laws in Louisiana and Oregon that allowed people accused of serious crimes to be convicted by a non-unanimous jury vote. The 6-to-3 decision overturned a longstanding prior ruling from 1972, which had upheld such non-unanimous verdicts in state courts.

And these days, any decision to overturn a longstanding precedent rings the alarm bells in the Supreme Court.

In the short run, Monday's decision was a victory for Evangelisto Ramos, who in 2016 was convicted of second-degree murder by a jury vote of 10-to-2 in Louisiana.

Only two states--Louisiana and Oregon--had provisions allowing non-unanimous verdicts, and Louisiana just recently changed its law to be like those in 48 other states and the federal government.

Justice Neil Gorsuch, writing for the majority, laid out the history behind the laws in both states. Gorsuch noted that the measure was first added to the Louisiana state constitution in 1898, after the Supreme Court ruled that racial minorities could not be barred from juries; that same year, Louisiana added the non-unanimous jury provision to its state constitution as part of a package of amendments that deliberately made it difficult for black citizens to vote or otherwise participate meaningfully in the state's governance. Specifically, Gorsuch said, the non-unanimous jury provision was a way to ensure that even if one or two African Americans made it on to a jury, their participation would be "meaningless."

The adoption of the non-unanimous jury rule in Oregon, Gorsuch wrote, "can similarly be traced to the rise of the Ku Klux Klan and efforts to dilute the influence of racial and ethnic and religious minorities on Oregon juries."

Despite these state provisions, there has never been any dispute that the unanimous jury requirement applies to the federal government. The question in this case was whether that aspect of the Sixth Amendment right to a jury trial applied to the states as well.

Over the last 75 years or so, the court has applied just about every other provision of the Bill of Rights to the states, but in 1972 it deviated from that practice, declining to apply the unanimous jury requirement in a similar fashion.

On Monday, however, the 1972 decision came tumbling down. The six-justice court majority — composed of conservatives and liberals — said the earlier ruling was a mistake.

The decision, written by the conservative Gorsuch, was joined in whole or in part by liberal Justices Ruth Bader Ginsburg, Stephen Breyer, Sonia Sotomayor, and conservative Justice Brett Kavanaugh. Justice Clarence Thomas, another conservative, agreed with the result, but on entirely different grounds.

Writing for the dissenters, Justice Samuel Alito — joined by Chief Justice John Roberts and for the most part, Justice Elena Kagan — maintained that the principle of adhering to precedent should be followed in this case because to do otherwise would require "a potentially crushing" number of new trials for people currently imprisoned under the old rule.

"Where is the justice in that?" replied Justice Gorsuch. "Not a single member of this court" is prepared to say that the 1972 decision was correct, he noted. "Every judge must learn to live with the fact that he or she will make mistakes ... But it is something else entirely to perpetuate" a wrong "only because we fear the consequences of being right."

The consequences of Monday's decision will likely be felt more in Louisiana, which allowed non-unanimous verdicts for more serious crimes than Oregon. The court's decision will require retrials for any prisoner who still has appeals pending.

There are about 100 of those cases in Louisiana, says Jamila Johnson, the managing attorney at the Promise of Justice Initiative, which represented Ramos. But there are also at least 1,700 prisoners in the state who might qualify for a new trial if the court eventually holds that Monday's decision is retroactive.

The high court left that question open for another day.

Altogether the majority, concurring, and dissenting opinions totaled a whopping 86 pages and reflected an important subtext--divergent views about when the court should follow its usual rule of adhering to precedent and when it should not.

It's important because, the new ultra-conservative court majority has very different views than the courts of the last 75 years on topics as diverse as abortion, voting rights, federal regulation, and the clash between religious views and generally applicable laws.

"The court's views about when it's OK to overrule prior precedent have always been more about the eye of the beholder than they have been about a rule that is easy or straightforward to apply," says Deborah Pearlstein, professor and co-director of the Floersheimer Center for Constitutional Democracy at Cardozo School of Law. Ultimately, she said, "all of these major questions that are coming before the court are going to be fought along these lines."

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Local Donation Centers Process Year-End Rush Of Contributions

Donations fill up the entryway to a Goodwill Southern California Donation Center in Pasadena during the first week of 2020.; Credit: Carla Javier/KPCC

Carla Javier

Now that the holiday season is winding down, thrift shops run by Goodwill, the Salvation Army, and other organizations are tallying up the annual flood of December donations. 

"It's always been a tradition that our donors donate between Christmas and New Year's ... and the last couple days of the year, they donate even more," Goodwill Southern California director of logistics Tinna Bauer explained. "Some do it for tax purposes, and some ... when they if they receive new items for Christmas, they clean out the old."

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Dr.Web quietly decrypting TorrentLocker for paid customers or distributors




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Refinery strike could mean higher gas prices

Tesoro says it’s been planning for a strike and will continue operating two of the effected refineries, including one in Carson.; Credit: Getty Images

Ben Bergman

More than 800 workers walked off the job early Sunday at an oil refinery in Carson because of a labor dispute, joining workers at eight other refineries around the country. 

National strikes have been rare in the refining business. The last one happened in 1980, and it took three months to resolve. If this dispute lasts that long, analysts say gas prices could rise.

“It’s very possible we may have seen the last of two dollar gasoline in the near term,” said Carl Larry director of oil and gas at consulting firm Frost & Sullivan. “Without production from these refineries, we’re going to see tighter supply and higher prices."

Making matters worse, many refineries are switching over to summer blend gas, which is cleaner burning, but also more expensive.

Jim Burkhard, Managing Director at IHS Cambridge Energy Research Associates, cautions that it is too soon to know what the effect of the strike will be, and even though the steelworkers have 64 percent of U.S. oil output in their hands, there’s still a lot of other supply.

 “Remember the oil market overall is very well supplied right now,” said Burkhard. "There's plenty of refining capacity around the world, you would just have some modification of trade flows."

The Carson refinery processes 363,000 barrels per day at peak capacity and employs 1,450 workers. Tesoro Corporation, which operates the plant, says it’s been planning for a strike and will continue operations.

"Tesoro is confident that the Company can continue to safely operate the refineries and meet customer commitments until resolution is reached with the [United Steel Workers]," Tesoro said in a written statement.

The USW represents workers at 65 U.S. refineries. It says the facilities where workers have not walked out will continue operating under a rolling 24-hour contract extension. 

“This work stoppage is about onerous overtime; unsafe staffing levels; dangerous conditions the industry continues to ignore; the daily occurrences of fires, emissions, leaks and explosions that threaten local communities without the industry doing much about it; the industry’s refusal to make opportunities for workers in the trade crafts; the flagrant contracting out that impacts health and safety on the job; and the erosion of our workplace, where qualified and experienced union workers are replaced by contractors when they leave or retire,” USW International Vice President Gary Beevers said in a written statement.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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From Sriracha sauce to jet engine parts, LAEDC tries to keep jobs in LA

The LAEDC helped Huy Fong Foods reach a compromise to keep operating its Sriracha factory in Irwindale ; Credit: Maya Sugarman/KPCC

Brian Watt

Even as California loses manufacturing jobs, a program run by the Los Angeles County Economic Development Corporation has fought to save some. 

When a company is considering relocating to take advantage of lower costs or an easier business climate, the LAEDC’s business assistance program steps in.  

It did so in the well-publicized case of Huy Fung Foods last year.  

When the city of Irwindale filed a lawsuit against the Sriracha sauce-maker because of bad smells, politicians from other states - most notably Texas - began to circle, offering the company a new home.  

Fighting against those suitors is a  familiar dance for the nonprofit Los Angeles County Economic Development Corporation. Many states and municipalities have similar agencies, whose job it is to try to attract and keep employers.

In the Sriracha case, the LAEDC prepared an economic impact analysis, met with the company and the South Coast Air Quality Management District and negotiated a compromise that kept the hot sauce manufacturer here, according to Carrie Rogers, Vice President of Business Assistance and Development with LAEDC.

"We all love Sriracha," she said, adding that she was happy to keep the "180 jobs and really to thwart the efforts of Governor Perry from Texas to try to lure our company away to their state."

The LAEDC estimates its business assistance program has played a role in keeping or luring 200,000 jobs since 1996, when it was formed. It's being recognized by the County Board of Supervisors for those efforts today.

But plenty of jobs still leave.

In a study published in July, the LAEDC said between 1990 and 2012, California lost about 40 percent of its manufacturing jobs – 842,180. 

"We compete internationally so a lot of our competitors have gone to Mexico," said Jeff Hynes, CEO of Covina-based Composites Horizons Incorporated, which makes ceramic structures for jet engines. "A week doesn’t go by that I don’t get a call from an economic development corp out of Texas or the South."

He scored a big contract recently and needed to expand fast to begin fulfilling orders. 

"Los Angeles  - in our particular industry - has a very good supplier base with materials and equipment," he said "but certainly facility costs are lower in other areas of the state and country."  

He said the LAEDC helped him get the permits quickly to buy and modify another building on its street and they decided to stay put. 

Composites Horizons currently employs 200 people but plans to add 50 employees this year and another 50 next year, he said. 

Rogers, of the LAEDC, said that may not seem like much, but it's important to support businesses like this one.

"When you take a step back and think about it, here’s a company that’s growing when many businesses aren’t," she said. "We know there are suppliers that feed into Composites Horizons. So when they get millions of dollars worth of contracts, we know that many more companies and employees around the county will be employed doing work directly for this company."

This content is from Southern California Public Radio. View the original story at SCPR.org.




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Seattle Genetics Shares Trade Higher on Q1/20 Earnings and 22% Growth in ADCETRIS Sales

Source: Streetwise Reports   05/01/2020

Seattle Genetics shares traded 8% higher, reaching a new 52-week high, after the company reported Q1/20 financial results which included a 10% y-o-y increase in net revenues fueled by a 22% increase in sales of ADCETRIS® and a strong debut for PADCEV™ in its first full quarter of sales.

Seattle Genetics Inc. (SGEN:NASDAQ) yesterday announced financial results for the first quarter ended March 31, 2020.

The company also provided an update on commercial results achieved in the quarter for its lead medicines including ADCETRIS® (brentuximab vedotin) and PADCEV™ (enfortumab vedotin-ejfv) and the U.S. Food and Drug Administration's (FDA) approval and launch of TUKYSA™ (tucatinib).

The company's President and CEO Clay Siegall, Ph.D., commented, "We have had a remarkable start to 2020, delivering record product sales in the first quarter that are now coming from both ADCETRIS and PADCEV. Notably, strong PADCEV sales in the first full quarter of launch reflect the unmet need among patients with metastatic bladder cancer...With the recent approval of TUKYSA for patients with metastatic HER2-positive breast cancer, we have now launched our third product just four months after our second...We are also preparing for European commercial operations and have hired general managers in major European markets ahead of potential ex-U.S. approvals of TUKYSA. With two new products, growing revenues, and an advancing pipeline of novel cancer programs, we have exciting prospects for future growth."

The company highlighted that ADCETRIS net sales in the U.S. and Canada increased by 22% to $164.1 million in Q1/20, compared to $135 million in Q1/19. The firm indicated that PADCEV net sales in the U.S. reached $34.5 million in Q1/20, which was its first full quarter of commercialization. The company added that royalty revenues in Q1/20 were $20.4 million and collaboration and license agreement revenues in Q1/20 totaled $15.6 million.

The firm reported a net loss for Q1/20 of $168.4 million, or $0.98 per diluted share, compared to net loss of $13.3 million, or $0.08 per diluted share for Q1/19. The company explained that "the net loss in Q1/20 included a net investment loss of $59.1 million primarily associated with its common stock holdings in Immunomedics, which are marked-to-market, compared to a net investment gain of $38.1 million in Q1/19."

The company advised that its TUKYSA was approved by the FDA for patients with HER2-positive metastatic breast cancer who have received one or more prior anti-HER2 regimens in the metastatic setting. The firm mentioned that it also expects to be able to report topline data in late Q2/20 or Q3/20 for the innovaTV 204 pivotal trial of tisotumab vedotin in patients with recurrent and/or metastatic cervical cancer who have relapsed or progressed after standard of care treatment.

The company noted that it is regularly monitoring the effects of the COVID-19 situation and is maintaining its business outlook estimates for FY/20 that it provided previously on February 6, 2020. For FY/20 it expects ADCETRIS net product sales of $675–700 million, royalty revenues of $105–115 million and collaboration and license agreement revenues of $30–50 million. The firm advised that for FY/20 it expects that R&D expenses will range from $860–950 million with SG&A expenses of $475–525 million.

Seattle Genetics is headquartered in Bothell, Wash., and is a global biotechnology company focused on discovering and commercializing cancer medicines.

Seattle Genetics has a market capitalization of around $23.7 billion with approximately 172.5 million shares outstanding. SGEN shares opened 2.75% higher today at $141.00 (+$3.77, +2.75%) over yesterday's $137.23 closing price and reached a new 52-week high price this morning of $157.00. The stock has traded today between $140.05 and $157.00 per share and is currently trading at $148.51 (+$11.28, +8.22%).

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Disclosure:
1) Stephen Hytha compiled this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. He or members of his household own securities of the following companies mentioned in the article: None. He or members of his household are paid by the following companies mentioned in this article: None.
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( Companies Mentioned: SGEN:NASDAQ, )




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IDEX Biometrics receives certification by an additional global payment network

IDEX Biometrics has announced that its dual interface...




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IDEX Biometrics to provide fingerprint sensors for Zwipe

IDEX Biometrics has announced it will provide its...




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Zwipe, Toppan join forces to bring biometric payment cards to Hong Kong and Macau

Zwipe has revealed it is teaming up with


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Stripe introduces global card support, card self-issuing, and revenue engine improvements

US-based payment technology company Stripe has introduced global...




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ACC payment card manufacturer to integrate Zwipe's biometric technology

Asia Credit Card Production (ACC) has selected 



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Thumbzup, First Distribution partner to process card transactions in Azure

South-Africa based PSP Thumbzup and cloud service distributor



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Impact of landfill caps on leachate emissions ??? an Austrian case study

Municipal solid waste (MSW) landfills, which consist of everyday consumer items, are potential long-term sources of emissions that could threaten the environment and human health if they are not managed carefully after closure. New research has presented a methodology to estimate future emission levels for closed MSW landfills and the impact of different aftercare strategies.




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Environmental impacts of electric vehicle batteries weighed up

A recent study has assessed the lifecycle environmental impact during the production and use phase of three battery types for plug-in hybrid (PHEV) and full performance battery electric vehicles (BEV). The study indicates that newer lithium-ion (Li-ion) technologies outperform current nickel-metal hydride (NiMH) batteries and identifies processes contributing to 13 environmental impacts




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Regulatory barriers to industrial symbiosis in metal sector

A new study has investigated the possibility of a regional industrial symbiosis of metal industries across the Sweden-Finland border. The analysis suggests that it is technologically feasible, but that regulatory support may be inefficient, particularly with respect to changing the status of a waste product to a by-product.




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World’s glaciers melting fast: 9.6 trillion tonnes of ice lost in last 50 years

The most comprehensive glacier assessment yet reveals that glacier melt was responsible for 27mm of sea level rise between 1961 and 2016. Ice loss from glaciers is now the second biggest contributor to rising sea levels after warming water. If glaciers continue to melt at current rates, most — including many in central Asia, central Europe, western Canada and the USA — will vanish during the second half of this century.




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Regulatory barriers to industrial symbiosis in metal sector

A new study has investigated the possibility of a regional industrial symbiosis of metal industries across the Sweden-Finland border. The analysis suggests that it is technologically feasible, but that regulatory support may be inefficient, particularly with respect to changing the status of a waste product to a by-product.




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Economic benefits drive industrial ecology

New research suggests that the main driver for industrial ecology initiatives is financial gain, whilst regulation plays a smaller role. Policy does influence their development but this tends to be indirectly through initiatives such as pollution control and waste reduction targets, rather than through direct regulation to enforce or encourage industrial ecology.




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Seafood labelling needs stricter enforcement

A new study finds that a quarter of fish products labelled as ‘cod’ or ‘haddock’ in Dublin, Ireland, are in fact completely different species of fish. This indicates that fish consumers are being misled by inaccurate labels, which could compromise sustainable fishing and consumption efforts.




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How To Log On To Bleeping Computer Chat With Trillian Basic




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With the land goes the water: ‘land grabbing’ redistributes global water resources

Under pressure from rising food prices, many nations have begun to acquire large tracts of agricultural land in foreign countries, a practice known as ‘land grabbing’. New research has now quantified current levels of land grabbing and demonstrated that it is accompanied by concerning levels of ‘water grabbing’ which could affect water supply in the ‘grabbed’ countries.




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Countries across Africa, Asia-Pacific vulnerable to Zika virus, new study finds

Parts of Africa and the Asia-Pacific region may be vulnerable to outbreaks of the Zika virus, including some of the world's most populous countries and many with limited resources to identify and respond to the mosquito-borne disease, a new study says.

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  • Health & Medicine

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Electric fans may exacerbate heat issues for seniors, study finds

Using electric fans to relieve high levels of heat and humidity may, surprisingly, have the opposite effect for seniors, a study by UT Southwestern Medical Center heart specialists suggests.

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  • Health & Medicine

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Climate change to reduce crop yields and increase child malnutrition

Adverse effects of climate change on agriculture will counteract any improvements in reducing levels of child malnutrition in the developing world, according to a new report, which calculates that twenty-five million more children will face malnutrition by 2050.




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Global pollinator decline may lead to human malnutrition

The worldwide decline of pollinators could increase cases of vitamin and micronutrient deficiencies in humans, new research suggests. For instance, pollination is needed for the crops that produce half of all plant-derived vitamin A across much of south-east Asia. Furthermore, areas which depend most on pollination for micronutrient supply tend to be poorer and already at higher risk of deficiencies.




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Assessment of total annoyance caused by combined industrial noises

A new study has assessed the annoyance caused by a combination of noises typically found on an industrial site. The results could help improve total noise annoyance prediction models. For example, it was found that ‘broadband’ noises, which consist of a wide range of frequencies, lead to more annoyance if they are combined with a specific additional set of low frequency noises, which can lead to an overall identical noise level.




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Ransomware with extension .trix and .xraw




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Eco-design should consider how users maintain non-electrical products

The lifetime environmental impacts of non-electrical consumer products, such as clothes, could be cut by over 40% if consumers maintained them in a more environmentally friendly manner, new research suggests. The study found the impacts of eco-designed products fell significantly when user guidelines were included in the eco-design.




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Chinese supply of critical raw materials could pose long-term risks to European wind- and solar-energy industries

A recent study has analysed risks to European renewable industries from the Chinese supply of critical raw materials. The offshore wind sector was found to be the most vulnerable of the renewable industries to supply risks. EU and industry strategies should be able to deal with these supply risks in the short term, but there are potential long-term risks to solar and wind sectors. The development of alternative technologies less reliant on these raw materials, and methods to recycle these materials is, therefore, a priority.




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The impact of climate change on Europe's electricity demand

The impact of climate change on electricity consumption is important to both adaptation and mitigation policies. New research has estimated that over the next 100 years climate change could cause up to a 20 per cent decrease in demand for electricity for heating in Northern Europe and up to a 20 per cent increase in demand for electricity for cooling in Southern Europe.




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GHG policy should cover 'upstream' electric vehicle emissions

Regulators should establish a process to consider the full lifecycle greenhouse gas (GHG) emissions of electric vehicles, according to a new US study. This would help ensure that vehicle emissions regulations are placed on a sound scientific basis, manufacturers continue to improve the efficiency of electric vehicles, and the full benefit of regulations to limit GHG emissions from vehicles are realised, say the researchers.




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Electricity grid adaptation to climate change in Norway and Sweden

A recent study has explored how national regulations and culture, company size and experience with weather incidents have influenced adaptation to climate change in electricity distribution companies in Norway and Sweden. Smaller companies in a strongly regulated environment, with less experience of extreme weather events, find it more difficult to pursue climate change adaption results,




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Energy efficiency of local food distribution can match globalised systems

Some scientists have suggested that, when all potential inefficiencies are accounted for, local food distribution systems may be less sustainable than globalised systems. However, new research examining the behaviour of participants in local food networks in France suggests that they can be as energy efficient as globalised systems.




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Potential of zero energy buildings for district heating systems assessed

Denmark aims to develop an energy system based only on renewable energy sources by 2050. Energy saving buildings are an essential part of this plan, according to new research, which investigates how excess heat production from net zero energy buildings (NZEBs) can benefit district heating systems and reduce reliance on combustible fuels.




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E-waste in developing countries needs careful management

Rapidly rising sales of electronic goods could cause huge amounts of hazardous electronic waste (e-waste) to build up in developing countries over the next 10 years, a new study has concluded. Prompt action is needed to ensure e-waste is properly managed in emerging economies to protect the environment and human health.