This fall, five South Carolina high schools will offer an aerospace curriculum to develop the next generation of aviation technology talent in a state where officials say the industry is thriving.

The state's supreme court ruled that it is not its role to tell the legislature how to spend its money, ending a 24-year school-funding battle.

Education Secretary Betsy DeVos has finally OK'd Florida's plan to implement the Every Student Succeeds Act. That means that single state, plus Puerto Rico and the District of Columbia, has gotten the go-ahead for its plan.

The U.S. Supreme Court blocked an injunction that had allowed a group backing an Idaho education spending measure to collect electronic signatures because of the coronavirus pandemic.

Charter schools are playing a notable role in remarks about education from candidates like Joe Biden and Bernie Sanders. Yet it's not clear what if any role they'll have in important states like Iowa and New Hampshire.

The justices declined to hear the appeal of the Ferguson-Florissant district over its at-large board elections, which lower courts invalidated as violating the Voting Rights Act.

In three days of rock climbing, orienteering, and other challenging outdoor experiences, principals get to examine their own—and others’—strengths and weaknesses as leaders.

When Scott Gann learned his son Dustin had dyslexia, he was shocked at the school's reaction. No one there wanted to use the word.

Worried that far too many students have weak reading skills, states are passing new laws that require aspiring teachers—and, increasingly, teachers who are already in the classroom—to master reading instruction that’s solidly grounded in research.

The Arkansas Department of Education will now provide on-site help for schools and districts in the state that are experiencing cybersecurity incidents.

Alexandria Area High School was created to accommodate changes in education and technology.

The Montreal Canadiens are not the only team in the midst of a rebuild and it's not easy for anybody, especially not for Craig Conroy who's at the helm of the Calgary Flames and will be down a first-round pick at the next draft.

Knight receives a more traditional start, at home, with days off ahead of the game

The Oilers look to claw themselves up above .500 against the team that started their memorable turnaround last season.

The Pittsburgh Penguins traded Lars Eller to the Washington Capitals for two draft picks after a blowout loss dropped them to 6-9-2 on the season.

Texas Longhorns fans were very happy after the second edition of the College Football Playoff rankings were released Tuesday.

The second College Football Playoff Top 25 rankings were revealed on Tuesday and the now-7-2

The CFP's annual love affair with the SEC appears finished. The latest rankings dropped a hammer on the mighty league where "it just means more."

The GHSA football playoffs kick off Friday night with several area teams competing, while the GIAA playoffs move to the state semifinal round, where two local schools look to secure a spot in the championship game. Friday night’s matchups: Luella (5-5) at No. 6 Westover (9-1) Luella travels to Albany after finishing 4-2 in Region 5, capping their regular season with a 35-25 win over ...

Worried that far too many students have weak reading skills, states are passing new laws that require aspiring teachers—and, increasingly, teachers who are already in the classroom—to master reading instruction that’s solidly grounded in research.

The court revived a lawsuit claiming that Mississippi's lack of a "uniform" education system violates the 1868 federal law that readmitted the state to the Union.

The U.S. Supreme Court took up the question of whether courts must find a juvenile offender permanently incorrigible before a sentence of life without parole.

A union lobbyist who worked just one day as a substitute teacher is entitled to a pension worth potentially tens of thousands of dollars annually, the Illinois supreme court has ruled.

It's Oregon women's basketball vs. Baylor in a marquee nonconference college basketball matchup. Follow for live score updates, game highlights.

Dazzling first with a relentless hawking defense that helped force 22 turnovers, then adding an almost frantic-paced offensive assault, the 2-0 No. 6-ranked Irish overwhelmed Purdue (1-1), 102-58, at Mackey Arena in West Lafayette, Ind. Dynamo guard Hannah Hidalgo was slapping, diving and picking pockets all night, making life miserable for any Boilermaker stuck bringing the ball up the floor. ► Snap Counts: Here's who played for Notre Dame football against Florida St.

Tennessee soccer earned an NCAA Tournament berth for the fourth straight season and will face No. 7 seed Virginia Tech in the first round Friday

On Wednesday at Moody Center, a Lamar team that went 24-7 last season should provide a tougher test for the Longhorns than in their season opener.

Yang Hu
Feb 24, 2021; 41:1699-1715
BehavioralSystemsCognitive

Yasmin L. Hurd
Oct 16, 2019; 39:8250-8258
Symposium and Mini-Symposium

Matthew F. Glasser
Aug 10, 2011; 31:11597-11616
BehavioralSystemsCognitive

The precise regulation of Ca²⁺ signals plays a crucial role in the physiological functions of neurons. Here, we investigated the rapid effect of glucocorticoids on Ca²⁺ signals in cultured hippocampal neurons from both female and male rats. In cultured hippocampal neurons, glucocorticoids inhibited the spontaneous somatic Ca²⁺ spikes generated by Kv2.1-organized Ca²⁺ microdomains. Furthermore, glucocorticoids rapidly reduced the cell surface expressions of Kv2.1 and Ca_V1.2 channels in hippocampal neurons. In HEK293 cells transfected with Kv2.1 alone, glucocorticoids significantly reduced the surface expression of Kv2.1 with little effect on K⁺ currents. In HEK293 cells transfected with Ca_V1.2 alone, glucocorticoids inhibited Ca_V1.2 currents but had no effect on the cell surface expression of Ca_V1.2. Notably, in the presence of wild-type Kv2.1, glucocorticoids caused a decrease in the surface expression of Ca_V1.2 channels in HEK293 cells. However, this effect was not observed in the presence of nonclustering Kv2.1S586A mutant channels. Live-cell imaging showed that glucocorticoids rapidly decreased Kv2.1 clusters on the plasma membrane. Correspondingly, Western blot results indicated a significant increase in the cytoplasmic level of Kv2.1, suggesting the endocytosis of Kv2.1 clusters. Glucocorticoids rapidly decreased the intracellular cAMP concentration and the phosphorylation level of PKA in hippocampal neurons. The PKA inhibitor H89 mimicked the effect of glucocorticoids on Kv2.1, while the PKA agonist forskolin abrogated the effect. In conclusion, glucocorticoids rapidly suppress Ca_V1.2-mediated Ca²⁺ signals in hippocampal neurons by promoting the endocytosis of Kv2.1 channel clusters through reducing PKA activity.

A new exhibition co-presented by the National Portrait Gallery and the Archives of American Art explores the seminal artist’s work

Berlin- FAO Director-General José Graziano da Silva has highlighted some of the most important events on the organization’s 2015 calendar during meetings with agriculture ministers who attended the Global Forum [...]

FAO, IFAD and WFP have launched a brand new Rome-based agencies (RBA) website. The RBAs share a common vision, guiding principles for enhanced collaboration and distinctive strengths that build [...]

To celebrate FAO’s 75^th anniversary, a new publication chronicles the history of the Organization and shares its vision for the future. FAO at 75 – Grow, nourish, sustain. Together provides a snapshot of [...]

To keep up to date on FAO’s most recent publications, sign up to the monthly newsletter produced by the Publications team of the Office of Communications, which provides a [...]

To keep up to date on FAO’s most recent publications, sign up to the monthly newsletter produced by the Publications team of the Office of Communications, which [...]

On the occasion of the fifth anniversary of the Paris Agreement, the event will highlight the key role of the agricultural sectors in supporting the Paris Agreement. The Paris Agreement, [...]

To keep up to date on FAO’s most recent publications, sign up to the monthly newsletter produced by the Publications team of the Office of Communications, which [...]

To keep up to date on FAO’s most recent publications, sign up to the monthly newsletter produced by the Publications team of the Office of [...]

To keep up to date on FAO’s most recent publications, sign up to the monthly newsletter produced by the Publications team of the Office of Communications, [...]

The Food and Agriculture Organization of the United Nations (FAO), in collaboration with the Secretariat of the Convention on Biological Diversity (CBD), will hold a Global Dialogue on the [...]

The FAO monthly publications newsletter produced by the Publications team of the Office of Communications is now also available in French. Sign up to receive updates on publications available in French [...]

The Tripartite organizations (FAO, OIE, WHO) invite partners to join public discussion on the establishment of the AMR Multi-Stakeholder Partnership Platform.

International fertilizer benchmark prices have risen throughout 2021.

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